New Bcl-2 Inhibitors

Catalog No. Product Name Information
F0129 Bcl-xL Antibody [D4A3]
E5962 BRD-810 BRD-810 is a potent and highly selective inhibitor of MCL1. BRD-810 targets the BH3-binding pocket of MCL1 and blocks the capturing of pro-apoptotic proteins, thereby rapidly triggering caspase activation in MCL1-dependent cells. It demonstrates potent anti-tumor effects in both hematologic malignancies and solid tumor models.
E8278 WH244 WH244 is a second-generation PROTAC that selectively degrades the anti-apoptotic proteins BCL-xL and BCL-2 with a DC50 of 0.6 nM for BCL-xL and 7.4 nM for BCL-2.
F2528 Bcl-XL Antibody [D5E6]
All Bcl-2 Inhibitors