HomeNew DNA Methyltransferase Inhibitors

New DNA Methyltransferase Inhibitors

Catalog No. Product Name Information
F2976 SF3B1 Rabbit mAb
E4795 Bobcat339 Bobcat339 is a cytosine-based small molecule inhibitor of TET enzyme with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively, reducing DNA 5hmC levels in hippocampal neurons. It is useful in epigenetics research and a potential starting point for therapeutics targeting DNA methylation and gene transcription.
E1556 GSK-3484862 GSK-3484862 is a non-covalent, potent and selective inhibitor of DNMT1 with an IC50 of 0.23 μM. It demonstrates efficacy in acute myeloid leukemia.
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