Thrombin

Inhibitory Selectivity

Thrombin Products

Catalog No. Information Product Use Citations Product Validations
S2196

Dabigatran (BIBR 953)

Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay.

S2154

Dabigatran Etexilate

Dabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.

S2069

Argatroban

Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.

S3200

Triflusal

Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.

S5252

Ozagrel sodium

Sodium ozagrel (ozagrel) is a thromboxane A2 synthase inhibitor with neuroprotective properties.

S4740

Sodium ferulate

Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.

S5074

Argatroban Monohydrate

Argatroban is a direct, selective thrombin inhibitor with anticoagulant effects.

S4502

Eltrombopag

Eltrombopag, a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).

S5286

Ramatroban

Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.

S2229

Eltrombopag Olamine

Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).

S1346

Heparin sodium

Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant.

Catalog No. Information Product Use Citations Product Validations
S2196

Dabigatran (BIBR 953)

Dabigatran (BIBR 953) is a potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM in a cell-free assay.

S2154

Dabigatran Etexilate

Dabigatran Etexilate is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.

S2069

Argatroban

Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.

S3200

Triflusal

Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.

S5252

Ozagrel sodium

Sodium ozagrel (ozagrel) is a thromboxane A2 synthase inhibitor with neuroprotective properties.

S4740

Sodium ferulate

Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.

S5074

Argatroban Monohydrate

Argatroban is a direct, selective thrombin inhibitor with anticoagulant effects.

Catalog No. Information Product Use Citations Product Validations
S4502

Eltrombopag

Eltrombopag, a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).

Catalog No. Information Product Use Citations Product Validations
S5286

Ramatroban

Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.

Catalog No. Information Product Use Citations Product Validations
S2229

Eltrombopag Olamine

Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).

Catalog No. Information Product Use Citations Product Validations
S1346

Heparin sodium

Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins, used as an anticoagulant.