RAR Selective Agonists
|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
|S4627||TTNPB (Arotinoid Acid)||
TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.
|Selective||RARγ, IC50: 9.3 nM; RARγ, IC50: 9.3 nM; RARβ , IC50: 4.5 nM; RARα, IC50: 5.1 nM|
Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.
Adapalene is a dual RAR and RXR agonist, used in the treatment of acne.
Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.
There are no products matching the selection yet, if you have any question please do not hesitate to contact us.