RAR Selective Agonists

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S4699	Etretinate	Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.	Selective
S1569	Tazarotene	Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.	Selective
S4627	TTNPB	TTNPB is a potent RAR agonist, and inhibits binding of [³H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Selective	RARα, IC50: 5.1 nM; RARβ , IC50: 4.5 nM; RARγ, IC50: 9.3 nM
S4260	Tamibarotene	Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.	Selective
S1276	Adapalene	Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.	Pan
S1653	Retinoic acid (Tretinoin)	Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.	Pan