Tretinoin (NSC 122758)

For research use only.

Catalog No.S1653 Synonyms: Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A

16 publications

Tretinoin (NSC 122758) Chemical Structure

CAS No. 302-79-4

Tretinoin (NSC 122758, Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

Selleck's Tretinoin (NSC 122758) has been cited by 16 publications

1 Customer Review

  • HL60 differentiation measured by expression of CD11b (flow cytometry) after a single dose exposure to HH1 or MC180295 for 4 days. 1 mM ATRA and high concentrations of DMSO (1.25%) were used as positive controls.

    Cell, 2018, 175(5):1244-1258. Tretinoin (NSC 122758) purchased from Selleck.

Purity & Quality Control

Choose Selective Retinoid Receptor Inhibitors

Biological Activity

Description Tretinoin (NSC 122758, Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.
Targets
RAR [1] RXR [1]
In vitro

Tretinoin prevents the cytotoxicity of H2O2 in cultured human mesangial cells by increasing both the catalase activity and the reduced glutathione content, which are dose- and time-dependent changes. Tretinoin-incubated mesangial cells leads to increased levels of catalase mRNA and gamma-glutamyl-cysteine synthetase (catalytic subunit) mRNA, the latter being the rate-limiting step in de novo reduced glutathione synthesis. [1] Tretinoin upregulates matrix metalloproteinase-13 and matrix metalloproteinase-8 in human keloid-derived fibroblasts. [2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human breast cancer cell SK-BR-3 MVjQdo9tcW[ncnH0bY9vKGG|c3H5 NW[0XoNuUW6qaXLpeIlwdiCxZjDFVk1v\WejdHn2[UBpfW2jbjDidoVie3RiY3HuZ4VzKGOnbHygV2suSlJvMzDwdo9tcW[ncnH0bY9vNCCLQ{WwQVAvODBzNzFOwG0> NHHpVmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkO3NlUzOCd-MUKzO|I2OjB:L3G+
T-47D cells M1\WbnBzd2yrZnXyZZRqd25iYYPzZZk> MVvJcohq[mm2aX;uJI9nKEWUIIDvd4l1cX[nIHj1cYFvKGK{ZXHzeEBk[W6lZYKgZ4VtdCCWLUS3SEBxem:uaX\ldoF1cW:wLDDJR|UxRTBwMjFOwG0> Ml;RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ|N{K1NlAoRjF{M{eyOVIxRC:jPh?=
F9 NEnMbIFHfW6ldHnvckBie3OjeR?= Mm\ORYJqdGm2eTD0c{BlcXOybHHj[UA{KHWPIILleIlvd2mmIHHu[EBcO0ifYXzsMZRz[W6|LYLleIlvd2mlIHHjbYQhcW5iRkmg[Y1jenmxbnHsJINiemOrbn;tZUBk\WyuczD1d4lv\yCIOTDQcIF{dWmwb3flckBC[3SrdnH0c5IhemWuZXHzbY5oKGG|c3H5MEBGTDVyPUCuNFAxOc7:TR?= M{jvclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5M{i4PFUoRjJ5M{i4PFU9N2F-
F9 NIHwZo5HfW6ldHnvckBie3OjeR?= M37lZ2FjcWyrdImgeI8h\Gm|cHzhZ4UhYzOKXXHscE11emGwcz3y[ZRqdm:rYzDhZ4llKG[{b32gSlkh\W2kconvcoFtKGOjcnPpco9u[SClZXzsd{whf2G|IHHzd4V{e2WmIHnuJIEhTjlibHHtbY5qdiC{ZXzlZZNmKGG|c3H5MEBGTDVyPUCuNFAyPc7:TR?= NYLjXpBIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezPFg5PSd-MkezPFg5PTxxYU6=
ASK MUfGeY5kfGmxbjDhd5NigQ>? M2Lrb|EhcHJ? MVjJcoR2[3Srb36gc4YhdW:{cHjvcI9ocWOjbDD0doFve2[xcn3heIlwdiCxZjDyZZQhSVONIHPlcIx{KGmwdH:gZZN1em:leYTld{Bi\nSncjCxJIhzKGK7IHzp[4h1KG2rY4Lvd4NweHluIFXEOVA:OTEQvF2= NGHIS4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OES5OlQyLz5{OES5OlQyRC:jPh?=
CV-1 M4HaRWZ2dmO2aX;uJIF{e2G7 NFnnVoNVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVoV1cW6xaXOgZYNq\CC{ZXPldJRweiCUQWKg[4FudWFuIFXDOVA:OC5yMEC3{txO Ml;HQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzR7MEeyOUc,PzR7MEeyOVww[T5?
CV-1 MWrGeY5kfGmxbjDhd5NigQ>? M37mV3Rz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDS[ZRqdm:rYzDhZ4llKHKnY3XweI9zKFKDUjDi[ZRiNCCHQ{WwQVAvODBzzszN Mk[5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzR7MEeyOUc,PzR7MEeyOVww[T5?
CV-1 MV3GeY5kfGmxbjDhd5NigQ>? Mn\4WJJidnOlcnnweIlwdmGuIHHjeIl3[XSrb36gbY4hS1ZvMTDj[YxteyCneIDy[ZN{cW6pIGLleIlvd2mlIHHjbYQhemWlZYD0c5IhWkGUIHHsdIhiNCCHQ{WwQVAvODB5zszN MmHxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzR7MEeyOUc,PzR7MEeyOVww[T5?
HL-60 cdm-1 MVfGeY5kfGmxbjDhd5NigQ>? NXz5OlhnXHKjboPncJV1[W2rbnHz[UBi[3Srdnn0fUBqdiCKTD22NEBk\G1vMTDj[YxteyxiRVO1NF0xNjByNd88US=> NGfOSVY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95NkO2PFQ{Lz55NkO2PFQ{RC:jPh?=
mouse embryo limb bud cells NUHyZVJRTnWwY4Tpc44h[XO|YYm= M4TkS2lvKH[rdILvJIlvcGmkaYTpc44hd2ZiY3jvcoRzd2enbnXzbZMhcW5ibX;1d4Uh\W2kconvJIxqdWJiYoXkJINmdGy|LDDJR|UxRTBwMEOx{txO NYHuTHZTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{[zOlg1Oyd-N{[zOlg1OzxxYU6=
leukemia cells M4eyR2Z2dmO2aX;uJIF{e2G7 NX\ncnR3XGinIHPvcoNmdnS{YYTpc44hemWzdXny[YQhfG9iaX7obYJqfCC2aHWgZolv\GmwZzDv[kBcO0ifQWTSRUB1dyC{ZYTpco9q[yCjY3nkJJJm[2WydH;yJIlvKGi3bXHuJJBzd227ZXzvZ5l1cWNibHX1b4VucWFiY3XscJMtKEmFNUC9NE4xODB4M988US=> M4LXelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd4M{[4O|koRjd4M{[4O|k9N2F-
CV-1 NFjHUWZHfW6ldHnvckBie3OjeR?= NVK2SVR7SmmwZHnu[{Bi\m[rbnn0fUBi\2GrboP0JJJmfGmwb3njJGFkcWRiZ3HtcYEhemWlZYD0c5J{KGOxLYTyZY5{\mWldHXkJIlvfG9iQ2[tNUBk\WyuczygSWM2OD1yLkCx{txO MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85OzB6OE[3K|45OzB6OE[3QE9iRg>?
CV-1 MVHGeY5kfGmxbjDhd5NigQ>? MlP6Rolv\GmwZzDh[oZqdmm2eTDh[4FqdnO2IILleIlvd2mlIFHjbYQh[mW2YTDy[YNmeHSxcoOgZ48ufHKjboPm[YN1\WRiaX70c{BEXi1zIHPlcIx{NCCHQ{WwQVAvODkQvF2= NEPkTHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96M{C4PFY4Lz56M{C4PFY4RC:jPh?=
CV-1 M4\3VmZ2dmO2aX;uJIF{e2G7 MV7CbY5lcW6pIHHm[olvcXS7IHHnZYlve3RicnX0bY5wcWNiQXPp[EBidHCqYTDy[YNmeHSxcoOgZ48ufHKjboPm[YN1\WRiaX70c{BEXi1zIHPlcIx{NCCHQ{WwQVAvOzYQvF2= MlnPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDNyOEi2O{c,QDNyOEi2O|ww[T5?
CV-1 M{HUemZ2dmO2aX;uJIF{e2G7 M4jlTGJqdmSrbnegZYZncW6rdImgZYdicW6|dDDy[ZRqdm:rYzDBZ4llKFhiYXzwbIEhemWlZYD0c5J{KGOxLYTyZY5{\mWldHXkJIlvfG9iQ2[tNUBk\WyuczygSWM2OD1yLkpOwG0> NVXnSGFCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEOwPFg3Pyd-OEOwPFg3PzxxYU6=
CV-1 Ml;DSpVv[3Srb36gZZN{[Xl? M1PjSWJqdmSrbnegZYZncW6rdImgZYdicW6|dDDy[ZRqdm:rYzDBZ4llKFhiZ3HtcYEhemWlZYD0c5J{KGOxLYTyZY5{\mWldHXkJIlvfG9iQ2[tNUBk\WyuczygSWM2OD1zLkJOwG0> Mnz4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDNyOEi2O{c,QDNyOEi2O|ww[T5?
CV-1 MVLGeY5kfGmxbjDhd5NigQ>? MVvCbY5lcW6pIHHm[olvcXS7IHHnZYlve3RicnX0bY5wcWNiQXPp[EBZKGKndHGgdoVk\XC2b4LzJINwNXS{YX7z[oVkfGWmIHnueI8hS1ZvMTDj[YxteyxiRVO1NF0yNjUQvF2= NV3GdGpMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEOwPFg3Pyd-OEOwPFg3PzxxYU6=
F9 NVvmVmF6TnWwY4Tpc44h[XO|YYm= NX\veVhYUW5idnn0do8heHKxbX;0bY9vKG:oIIDsZZNucW6xZ3XuJIFkfGm4YYTvdkB{\WO{ZYTpc44h\nKxbTDGPUApdXW{aX7lJJRmemG2b3PhdoNqdm:vYTmgZ4VtdHNuIFHDOVA:OC5{zszN NYLPc3kyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEW0OFE4PSd-OEW0OFE4PTxxYU6=
CV-1 M3fmcGZ2dmO2aX;uJIF{e2G7 MUPUdoFve2O{aYD0bY9v[WxiYXP0bZZifGmxbjDpckBEXi1zIHPlcIx{KGW6cILld5NqdmdiUnX0bY5wcWNiYXPp[EBz\WOncITvdkBTSVJiZ3HtcYEtKEWFNUC9NE4xOzQQvF2= NXfKWpBMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEewPVA6PCd-OEewPVA6PDxxYU6=
CV-1 NHjaOpdHfW6ldHnvckBie3OjeR?= M3fBc3Rz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDS[ZRqdm:rYzDhZ4llKHKnY3XweI9zKFKDUjDi[ZRiNCCHQ{WwQVAvOTB3zszN NIOz[Wk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96N{C5NFk1Lz56N{C5NFk1RC:jPh?=
CV-1 NWXmcpdSTnWwY4Tpc44h[XO|YYm= MlPGWJJidnOlcnnweIlwdmGuIHHjeIl3[XSrb36gbY4hS1ZvMTDj[YxteyCneIDy[ZN{cW6pIGLleIlvd2mlIHHjbYQhemWlZYD0c5IhWkGUIHHsdIhiNCCHQ{WwQVAvPTZ|zszN M3fnZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzh5MEmwPVQoRjh5MEmwPVQ9N2F-
CV-1 MkmxSpVv[3Srb36gZZN{[Xl? NIO3e4RVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVoV1cW6xaXSgXEBz\WOncITvdkBTYFJiYXzwbIEtKEWFNUC9NU4xQDUQvF2= NFfHNFU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96N{C5NFk1Lz56N{C5NFk1RC:jPh?=
CV-1 MlXTSpVv[3Srb36gZZN{[Xl? M4TMeXRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDS[ZRqdm:rZDDYJJJm[2WydH;yJHJZWiCpYX3tZUwhTUN3ME2xMlIzPc7:TR?= NGPWVZQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96N{C5NFk1Lz56N{C5NFk1RC:jPh?=
CV-1 NG\vfmZHfW6ldHnvckBie3OjeR?= NFfvW3BVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVoV1cW6xaXSgXEBz\WOncITvdkBTYFJiYnX0ZUwhTUN3ME2xMlM6PM7:TR?= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85PzB7MEm0K|45PzB7MEm0QE9iRg>?
HL-60 MVvGeY5kfGmxbjDhd5NigQ>? M2LDUmlv\HWldHnvckBw\iC2cnHud4dtfXSjbXnuZZNmKCiWR3Hz[Ukh[WO2aY\peJkhcW5iSFytOlAh[2WubIOsJGVEPTB;MD6wNFXPxE1? MkfRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDd6NES1OEc,QDd6NES1OFww[T5?
embryonic limb bud cells NIDLUndHfW6ldHnvckBie3OjeR?= M2O0RmlvcGmkaYTpc44hd2ZiQ3jvcoRzd2enbnXzbZMhcW5iZHH5JFEyKGWvYoL5c45q[yCuaX3iJIJ2\CClZXzsd{whUUN3ME2wMlA{Oc7:TR?= MkXTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDd6NES1OEc,QDd6NES1OFww[T5?
CV-1 Moe5SpVv[3Srb36gZZN{[Xl? NUT0dGJzXHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJHJmfGmwb3njJIFkcWRicnXj[ZB1d3JiUlHSJIdidW2jLDDFR|UxRTBwMENOwG0> MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek85QTd6OEOyK|45QTd6OEOyQE9iRg>?
CV-1 NUf2fIc3TnWwY4Tpc44h[XO|YYm= M4rTPXRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDS[ZRqdm:rYzDhZ4llKHKnY3XweI9zKFKDUjDi[ZRiNCCHQ{WwQVAvODh5zszN M2naSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzh7N{i4N|IoRjh7N{i4N|I9N2F-
CV-1 NEPiVYxHfW6ldHnvckBie3OjeR?= NUnKWJZjXHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJHJmfGmwb3njJIFkcWRicnXj[ZB1d3JiUlHSJIFteGijLDDFR|UxRTBwNEW5{txO MnLxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDl5OEizNkc,QDl5OEizNlww[T5?
CV-1 MX;GeY5kfGmxbjDhd5NigQ>? NGLNT4RVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegdoV1cW6xaXSgRUBz\WOncITvdkBTSVJiYnX0ZUwhTUN3ME2wMlAxOs7:TR?= NGfuXYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi97NUeyPFk{Lz57NUeyPFk{RC:jPh?=
CV-1 Mk\ySpVv[3Srb36gZZN{[Xl? NX\lTVA1XHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJJJmfGmwb3nkJHghemWlZYD0c5IhWliUIHfhcY1iNCCHQ{WwQVAvODB4zszN Ml3mQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQTV5Mki5N{c,QTV5Mki5N|ww[T5?
CV-1 NUDsbVJSTnWwY4Tpc44h[XO|YYm= M1GyWnRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDy[ZRqdm:rZDDBJJJm[2WydH;yJHJCWiCjbIDoZUwhTUN3ME2wMlAzOs7:TR?= Mo[zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQTV5Mki5N{c,QTV5Mki5N|ww[T5?
HL-60 NUO0WG1CTnWwY4Tpc44h[XO|YYm= NULYfYIyUW6mdXP0bY9vKG:oIFjMMVYxKGOnbHzzJIRq\m[ncnXueIlifGmxbjDveoVzKDRiZHH5d{whTUR3ME2wMlEz|ryP MlX6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQTV5Mki5N{c,QTV5Mki5N|ww[T5?
HL-60 MXXDfZRwe3SjdHnjJIF{e2G7 MVfDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgTGwuPjBiY3XscJMtKEmFNUC9NVHPxE1? M{j4SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyNUi1NlA3Lz5zMEW4OVIxPjxxYU6=
CV-1 NFTqdpdHfW6ldHnvckBie3OjeR?= MXHUdoFve2O{aYD0bY9v[WxiYXP0bZZifGmxbjDpckBEXi1zIHPlcIx{KGW6cILld5NqdmdiUlHSJIdidW2jIILlZ4VxfG:{LDDFR|MxRTBwMECwNlLPxE1? MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODd4MkCzPEc,OTB5NkKwN|g9N2F-
CV-1 M2i3V2Z2dmO2aX;uJIF{e2G7 MkG1WJJidnOlcnnweIlwdmGuIHHjeIl3[XSrb36gbY4hS1ZvMTDj[YxteyCneIDy[ZN{cW6pIGLBVkBj\XSjIILlZ4VxfG:{LDDFR|MxRTBwMECwPVPPxE1? MoDhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB5NkKwN|goRjFyN{[yNFM5RC:jPh?=
CV-1 M4juSmZ2dmO2aX;uJIF{e2G7 MVzUdoFve2O{aYD0bY9v[WxiYXP0bZZifGmxbjDpckBEXi1zIHPlcIx{KGW6cILld5NqdmdiUlHSJIFteGijIILlZ4VxfG:{LDDFR|MxRTBwMECwPVnPxE1? MkDzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB5NkKwN|goRjFyN{[yNFM5RC:jPh?=
CV-1 MmTSSpVv[3Srb36gZZN{[Xl? M3L1XnJmdGG2aY\lJJRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDSRXIh[WyyaHGgdoVk\XC2b4KgZ49ueGG{ZXSgeI8hSVSUQTygVoVt[XSrdnWgSWM{OD1yLkCwNe69VQ>? NYjJVmxxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUC3OlIxOzhpPkGwO|YzODN6PD;hQi=>
CV-1 MUDGeY5kfGmxbjDhd5NigQ>? NGTJOIZT\WyjdHn2[UB1emGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVmFTKGKndHGgdoVk\XC2b4KgZ49ueGG{ZXSgeI8hSVSUQTygVoVt[XSrdnWgSWM{OD1yLkCwNe69VQ>? MoC4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB5NkKwN|goRjFyN{[yNFM5RC:jPh?=
CV-1 NY\YToZrTnWwY4Tpc44h[XO|YYm= M1K5XnJmdGG2aY\lJJRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDSRXIh\2GvbXGgdoVk\XC2b4KgZ49ueGG{ZXSgeI8hSVSUQTygVoVt[XSrdnWgSWM{OD1yLkCwNe69VQ>? NHrSOlk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEe2NlA{QCd-MUC3OlIxOzh:L3G+
CV-1 NHO1bppHfW6ldHnvckBie3OjeR?= NYjLcnJnXHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJHJCWiCpYX3tZUBz\WOncITvdkwhTUN|ME2wMlAxODF6zszN MlrOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB5NkKwN|koRjFyN{[yNFM6RC:jPh?=
CV-1 Mn3zSpVv[3Srb36gZZN{[Xl? NF\OTmpVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVmFTKGKndHGgdoVk\XC2b4KsJGVEOzB;MD6wNFA3Qc7:TR?= Mn74QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB5NkKwN|koRjFyN{[yNFM6RC:jPh?=
CV-1 MnHtSpVv[3Srb36gZZN{[Xl? NGPFfItVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegVmFTKGGucHjhJJJm[2WydH;yMEBGSzNyPUCuNFAyOc7:TR?= NH3uXJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEe2NlA{QSd-MUC3OlIxOzl:L3G+
COS NIXie4xHfW6ldHnvckBie3OjeR?= MnPlWJJidnOlcnnweIlwdmGuIHHjeIl3[XSrb36gbY4hS0:VIHPlcIx{KGW6cILld5NqdmdiUlHSMYdidW2jLDDS[YxifGm4ZTDFR|MxRTBwMECwNlbPxE1? NYHIXW5URGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUC5OVYzODFpPkGwPVU3OjBzPD;hQi=>
COS M4[w[2Z2dmO2aX;uJIF{e2G7 NETkVItVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFT2OgZ4VtdHNiZYjwdoV{e2mwZzDSRXIu[mW2YTygVoVt[XSrdnWgSWM{OD1yLkCwNlLPxE1? NFnkemk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMEm1OlIxOSd-MUC5OVYzODF:L3G+
COS MXHGeY5kfGmxbjDhd5NigQ>? M{HCPXRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEORUzDj[YxteyCneIDy[ZN{cW6pIGLBVk1idHCqYTygVoVt[XSrdnWgSWM{OD1yLkCwN|TPxE1? NUTvUnVlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUC5OVYzODFpPkGwPVU3OjBzPD;hQi=>
HL60 NIrpU25HfW6ldHnvckBie3OjeR?= NHjpU3JKdiC4aYTyc{BkgXSxdH;4bYNqfHliYXfhbY5{fCCKTE[wJINmdGy|LDDJR|UxRTFzzszN M3\POFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzMUK4OlQ5Lz5zMUGyPFY1QDxxYU6=
CV-1 NWPa[XRuTnWwY4Tpc44h[XO|YYm= MonVWJJidnOlcnnweIlwdmGuIHHjeIl3[XSrb36gbY4hS1ZvMTDj[YxteyCneIDy[ZN{cW6pIHj1cYFvKFKndHnuc4lkKGGlaXSgdoVk\XC2b4KgVmFTKGejbX3hMEBGSzVyPUCuNFE6|ryP MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjR6MkSzOUc,OTJ2OEK0N|U9N2F-
CV-1 MnjqSpVv[3Srb36gZZN{[Xl? NUftR5ZHXHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJIh2dWGwIGLleIlvd2mlIHHjbYQhemWlZYD0c5IhWkGUIHLleIEtKEWFNUC9NE4xPzkQvF2= NVq5[FRuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK0PFI1OzVpPkGyOFgzPDN3PD;hQi=>
CV-1 NIjoRZhHfW6ldHnvckBie3OjeR?= M4jLOXRz[W6|Y4LpdJRqd26jbDDhZ5RqfmG2aX;uJIlvKEOYLUGgZ4VtdHNiZYjwdoV{e2mwZzDoeY1idiCUZYTpco9q[yCjY3nkJJJm[2WydH;yJHJCWiCjbIDoZUwhTUN3ME2wMlQ{Ps7:TR?= NXfMVHZCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUK0PFI1OzVpPkGyOFgzPDN3PD;hQi=>
CV-1 MVjGeY5kfGmxbjDhd5NigQ>? MU\UdoFve2O{aYD0bY9v[WxiYXP0bZZifGmxbjDpckBEXi1zIHPlcIx{KGW6cILld5NqdmdibX;1d4UhWmW2aX7vbYQhYCC{ZXPldJRweiCUWGKg[4FudWFuIFXDOVA:OC57NkJOwG0> M3nabVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{NEiyOFM2Lz5zMkS4NlQ{PTxxYU6=
CV-1 NEfJXppHfW6ldHnvckBie3OjeR?= NV7FUppUXHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hcW5iQ2[tNUBk\WyuczDlfJBz\XO|aX7nJIh2dWGwIGLleIlvd2mmIGigdoVk\XC2b4KgVnhTNWGucHjhMEBGSzVyPUGuNFE2|ryP Mnv4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2OEK0N|UoRjF{NEiyOFM2RC:jPh?=
CV-1 NFvBZ|dHfW6ldHnvckBie3OjeR?= NFfIUotVemGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBqdiCFVj2xJINmdGy|IHX4dJJme3OrbnegcY92e2ViUnX0bY5wcWRiWDDy[YNmeHSxcjDSXHIh[mW2YTygSWM2OD1zLkKxNe69VQ>? Mm\yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2OEK0N|UoRjF{NEiyOFM2RC:jPh?=
T47D NX;YUZJpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV22JIRigXN? MmPxS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gWFQ4TCClZXzsd{Bi\nSncjC2JIRigXNiYomgUXRVKGG|c3H5MEBKSzVyPUCuNFA3|ryP M4f4dVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NkG1OVIyLz5zNU[xOVUzOTxxYU6=
MCF7 NV\KVlNuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7hOpM3KGSjeYO= NIL0R3pIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFYh\GG7czDifUBOXFRiYYPzZZktKEmFNUC9NE42QM7:TR?= NHPCS|E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNU[xOVUzOSd-MUW2NVU2OjF:L3G+
MCF7 NGXHUmJCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MkTaRY51cXC{b3zp[oVz[XSrdnWg[YZn\WO2IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyxiSVO1NF0xNjV6NEZOwG0> MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTZzNUWyNUc,OTV4MUW1NlE9N2F-
PC3 M1LKfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{noO|Yh\GG7cx?= NGTVXlZIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOkBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3ME2y{txO MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTZzNUWyNUc,OTV4MUW1NlE9N2F-
LNCaP NUnhc|ZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV3VS2x1PiCmYYnz NXfFenNvT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVE6FYWCgZ4VtdHNiYX\0[ZIhPiCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NF0yOM7:TR?= NYjDW2VoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW2NVU2OjFpPkG1OlE2PTJzPD;hQi=>
F9 MXzGeY5kfGmxbjDhd5NigQ>? MWSzJIRigXN? NF3KfGRKdmS3Y4Tpc44hd2ZidHXycYlv[WxiZHnm[oVz\W62aXH0bY9vKGmwIH3veZNmKEZ7IHPlcIx{KGG|c3Xzd4VlKGK7IH3lZZN2emmwZzDz[YNz\XSnZDDwcIF{dWmwb3flckBi[3SrdnH0c5Ih[WO2aY\peJkh[W[2ZYKgN{Bl[Xm|LDDJR|UxRTBwMECwNe69VQ>? NV3nO5ZYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PFk2PzlpPkG3OFg6PTd7PD;hQi=>
Raji NUHmWZNyTnWwY4Tpc44h[XO|YYm= M1fFblQ5KGi{cx?= MV7Jcohq[mm2aX;uJI9nKFSSQT3pcoR2[2WmIFXwd5RmcW5vQnHydkB3cXK3czDlZZJtgSCjboTp[4VvKGGldHn2ZZRqd25iaX6gVoFrcSClZXzsd{Bi\nSncjC0PEBpenNuIFnDOVA:OC5yMUW0{txO M{n0ZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUCzPFUxLz5zN{WwN|g2ODxxYU6=
HaCaT Ml60SpVv[3Srb36gZZN{[Xl? NEn0TJhKdmO{ZXHz[UBqdiC2cnHud4NzcXC2aX;uZYwh[WO2aY\peJkhd2ZiUlHSZYxxcGFicnXj[ZB1d3JiZYDy[ZN{\WRiaX6gbJVu[W5iSHHDZXQh[2WubIOgZ48ufHKjboPm[YN1\WRid3n0bEBFWjVvdHutR2FVKHKncH;yeIVzKHCuYYPtbYQh[XO|ZYPz[YQh[XNiYnX0ZU1o[WyjY4Tvd4ll[XOnIHHjeIl3cXS7IHL5JGNCXC2HTFnTRS=> NVH5fYJWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NVEzQDNpPkG4OVEyOjh|PD;hQi=>
PC3 MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnfFOUBl[Xm| NEPldIFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[W[2ZYKgOUBl[Xm|IHL5JG1VXCCjc4PhfUwhT0l3ME23MlbPxE1? NHHIOnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW0N|kxOid-MUi1OFM6ODJ:L3G+
MDA-MB-231 M33HR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGnUZoE2KGSjeYO= NF32b4JIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIFnfGW{IEWg[IF6eyCkeTDNWHQh[XO|YYmsJGdKPTB;MUCuPFXPxE1? NWC2dI1MRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1OFM6ODJpPkG4OVQ{QTB{PD;hQi=>
COS7 M1\Ce2Z2dmO2aX;uJIF{e2G7 NEW4XoEyPiCqcoO= Mme3RYN1cX[rdImgZZQhcHWvYX6gVmFT\2GvbXGgcIlo[W6mIHLpcoRqdmdiZH;tZYlvKGW6cILld5Nm\CCrbjDDU3M4KGOnbHzzJINwNXS{YX7z[oVkfGWmIIfpeIghT2GuND3ERmQh[XO|ZYPz[YQh[XNidILhcpNkemmydHnvcoFtKGGldHn2ZZRqd25iYX\0[ZIhOTZiaILzJIJ6KEejbESgdoV{eG:wc3Wg[YxmdWWwdD3kdol3\W5ibIXjbYZmemG|ZTDy[ZBwenSncjDn[Y5mKGG|c3H5MEBGSzVyPUCuNFAxOs7:TR?= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3OEm2OUc,OTlyNUi5OlU9N2F-
COS7 MVvGeY5kfGmxbjDhd5NigQ>? MXqxOkBpenN? MkjsRYN1cX[rdImgZZQhcHWvYX6gVmFT[mW2YTDsbYdidmRiYnnu[Ilv\yCmb33hbY4h\XiycnXzd4VlKGmwIFPPV|ch[2WubIOgZ48ufHKjboPm[YN1\WRid3n0bEBI[Wx2LVTCSEBie3Onc4Pl[EBieyC2cnHud4NzcXC2aX;uZYwh[WO2aY\heIlwdiCjZoTldkAyPiCqcoOgZpkhT2GuNDDy[ZNxd26|ZTDlcIVu\W62LXTybZZmdiCudXPp[oVz[XOnIILldI9zfGW{IHflcoUh[XO|YYmsJGVEPTB;MD6wNVLPxE1? NFS3So09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1PFk3PSd-MUmwOVg6PjV:L3G+
COS7 M2ThcGZ2dmO2aX;uJIF{e2G7 NUXXVJJGOTZiaILz MYrBZ5Rqfmm2eTDheEBpfW2jbjDSRXJidHCqYTDsbYdidmRiYnnu[Ilv\yCmb33hbY4h\XiycnXzd4VlKGmwIFPPV|ch[2WubIOgZ48ufHKjboPm[YN1\WRid3n0bEBI[Wx2LVTCSEBie3Onc4Pl[EBieyC2cnHud4NzcXC2aX;uZYwh[WO2aY\heIlwdiCjZoTldkAyPiCqcoOgZpkhT2GuNDDy[ZNxd26|ZTDlcIVu\W62LXTybZZmdiCudXPp[oVz[XOnIILldI9zfGW{IHflcoUh[XO|YYmsJGVEPTB;MD6wNVfPxE1? NH3icIU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1PFk3PSd-MUmwOVg6PjV:L3G+
NIH3T3 MonwSpVv[3Srb36gZZN{[Xl? NHPpbJFC\2:waYP0JIFkfGm4aYT5JIF1KFKDUnLleIEzKGW6cILld5Nm\CCrbjDtc5V{\SCQSVizWFMh[2WubIOgZpkhWi2VQWSgZZN{[XluIFXDOVA:OC5yME[zNe69VQ>? M3PtcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlMxLz5zOUKzPVI{ODxxYU6=
NIH3T3 M3q0W2Z2dmO2aX;uJIF{e2G7 M2PvS2FkfGm4aYT5JIF1KFKDUnHsdIhiKGW6cILld5Nm\CCrbjDtc5V{\SCQSVizWFMh[2WubIOgZpkhWi2VQWSgZZN{[XluIFXDOVA:OC5yME[zNe69VQ>? MmT6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myN|AoRjF7MkO5NlMxRC:jPh?=
NIH3T3 M{HXVGZ2dmO2aX;uJIF{e2G7 MX7BZ5Rqfmm2eTDheEBTSVKkZYThNUBmgHC{ZYPz[YQhcW5ibX;1d4UhVkmKM2SzJINmdGy|IHL5JHIuW0GWIHHzd4F6NCCHQ{WwQVAvODJ3MUNOwG0> NEnYcGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI{OCd-MUmyN|kzOzB:L3G+
NIH3T3 MXfGeY5kfGmxbjDhd5NigQ>? MkPqRYN1cX[rdImgZZQhWkGUZ3HtcYEh\XiycnXzd4VlKGmwIH3veZNmKE6LSEPUN{Bk\WyuczDifUBTNVODVDDhd5NigSxiRVO1NF0xNjB3MEGy{txO MoG4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myN|AoRjF7MkO5NlMxRC:jPh?=
LNCAP MVXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NEHCfJY1QCCqcoO= NWjVT25JSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMUmNCWCClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyPUCuOe69VQ>? MmDZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|N{W4NlUoRjF7M{e1PFI2RC:jPh?=
LNCAP MkLSRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MnHpNVAhfU1? MmCxOFghcHK| NVvwTmZiSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMUmNCWCClZXzsd{Bie3Onc4Pl[EBieyCvYYjpcYFtKGWoZnXjeEBifCBzMDD1UUBi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5 MoTNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|N{W4NlUoRjF7M{e1PFI2RC:jPh?=
SK-N-SH MlT1SpVv[3Srb36gZZN{[Xl? M1TCdVIhfG9iNTD1US=> NGnvSlA1QCCqcoO= M{LXfWlv\HWldHnvckBw\iCwZYXybZRmKG:3dHfyc5d1cCCrbjDoeY1idiCVSz3OMXNJKGOnbHzzJIF1KDJidH:gOUB2VSCjZoTldkA1QCCqcoOgZpkh[3K7c4ThcEB3cW:uZYSgd5RicW6rbne= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTh{MU[xNEc,OTl6MkG2NVA9N2F-
SH-SY5Y NFq1TnlHfW6ldHnvckBie3OjeR?= MUGyJJRwKDVidV2= MVq0PEBpenN? MlvxTY5lfWO2aX;uJI9nKG6ndYLpeIUhd3W2Z4Lve5RpKGmwIHj1cYFvKFOKLWPZOXkh[2WubIOgZZQhOiC2bzC1JJVOKGGodHXyJFQ5KGi{czDifUBkenm|dHHsJJZqd2yndDDzeIFqdmmwZx?= MlriQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl6MkG2NVAoRjF7OEKxOlExRC:jPh?=
Neuro2a MXrGeY5kfGmxbjDhd5NigQ>? M4DYbFIhfG9iNTD1US=> M4TBd|Q5KGi{cx?= NXnXcpBMUW6mdXP0bY9vKG:oIH7leZJqfGVib4X0[5Jwf3SqIHnuJI1wfXOnIF7leZJwOmFiY3XscJMh[XRiMjD0c{A2KHWPIHHmeIVzKDR6IHjyd{BjgSClconzeIFtKH[rb3zleEB{fGGrbnnu[y=> Moj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl6MkG2NVAoRjF7OEKxOlExRC:jPh?=
U87 M1vhUWZ2dmO2aX;uJIF{e2G7 MknnNkB1dyB3IIXN M1nGR|Q5KGi{cx?= M4jaVGlv\HWldHnvckBw\iCwZYXybZRmKG:3dHfyc5d1cCCrbjDoeY1idiCXOEegZ4VtdHNiYYSgNkB1dyB3IIXNJIFnfGW{IES4JIhzeyCkeTDjdpl{fGGuII\pc4xmfCC|dHHpcolv\w>? MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTh{MU[xNEc,OTl6MkG2NVA9N2F-
P19 M2XhWmZ2dmO2aX;uJIF{e2G7 MYCyJJRwKDVidV2= NGTRXFE1QCCqcoO= NW\MWooxUW6mdXP0bY9vKG:oIH7leZJqfGVib4X0[5Jwf3SqIHnuJI1wfXOnIGCxPUBk\WyuczDheEAzKHSxIEWgeW0h[W[2ZYKgOFghcHK|IHL5JINzgXO2YXygeolwdGW2IIP0ZYlvcW6p NInBTmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUiyNVYyOCd-MUm4NlE3OTB:L3G+
HT-29 M3fDT2N6fG:2b4jpZ4l1gSCjc4PhfS=> MofUOFghcHK| M2ixNmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUC9OE4{|ryP M2O3blxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNEC1PFQ6Lz5{MESwOVg1QTxxYU6=
MT3 M1vJTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NF\ze5M1QCCqcoO= NGTrS3BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOXDNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2xOO69VQ>? Mk[5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB2MEW4OFkoRjJyNEC1PFQ6RC:jPh?=
COLO205 NEHiNpdEgXSxdH;4bYNqfHliYYPzZZk> M3zDd|Q5KGi{cx?= NUHoPFZ4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0:OT{KwOUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxRTN5zszN NFHrPVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MESwOVg1QSd-MkC0NFU5PDl:L3G+
NB4 Mo[0R4VtdCCleXPs[UBie3OjeR?= MXexJJVO NVTHdm1JOjRiaILz M3jrdGNmdGxiY4njcIUh[XK{ZYP0JIlvKGi3bXHuJG5DPCClZXzsd{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDhZ4N2dXWuYYTpc44h[XRicILlMWcyKHCqYYPlJIF1KDFidV2gZYZ1\XJiMkSgbJJ{KGK7IF\BR3Mh[W6jbInzbZM> MoHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB2OUG0OFAoRjJyNEmxOFQxRC:jPh?=
HEK293T MoDLSpVv[3Srb36gZZN{[Xl? MUW0OUBucW6| MWfJcohq[mm2aX;uJI9nKG2xdYPlJGlldzJidILhcpNn\WO2ZXSgbY4hUEWNMkmzWEBk\WyuczD1d4lv\yCOLYTyfZB1d3CqYX6gZZMhe3Wkc4TyZZRmKGG|c3Xzd4VlKGG|IHv5cpVz\W6rbnWg[o9zdWG2aX;uJIFnfGW{IES1JI1qdnNiYomgd5Bm[3S{b4Doc5RwdWW2cnnjJIFv[Wy7c3nzMEBKSzVyPUK4MlfPxE1? MmL1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzMkK4OlUoRjJ|MUKyPFY2RC:jPh?=
SH-SY5Y M3HOO2Z2dmO2aX;uJIF{e2G7 M4i0XVExKHWP MV22JIRigXN? MYLJcoR2[3Srb36gc4Yh[2WubDDkbYZn\XKnboTpZZRqd25iaX6gbJVu[W5iU1itV3k2YSClZXzsd{Bie3Onc4Pl[EBieyCwZYXyZYwudGmtZTDkbYZn\XKnboTpZZRqd25iYYSgNVAhfU1iYX\0[ZIhPiCmYYnzJJV{cW6pIHLleIE{NXS3YoXsbY4h[W6mIF7GNlAxKHO2YXnubY5oKGK7IH3pZ5Jwe2OxcHnjJIFv[Wy7c3nz NEKzXG09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK2NlM4QCd-MkSyOlI{Pzh:L3G+
BL-21 (BL3) NXLVeWU5TnWwY4Tpc44h[XO|YYm= NV;0eGI{UW64ZYLz[UBi\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHJwWmNvTFLEJIZ2e2mxbjDwdo91\WmwIIfpeIghT1OWIHX4dJJme3OnZDDpckBDVC1{MTCoRmw{MSClZXzsd{Bie3Onc4Pl[EBieyCVUlOxJINw[WO2aY\heI9zKHCncITp[IUhemWlcoXpeI1mdnRuIFXDOVA:OTkQvF2= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVyMkOzOEc,OjR3MEKzN|Q9N2F-
F9 NIPlZpFHfW6ldHnvckBie3OjeR?= NIHsbHMxNjBzIIXN M2jQTVQ5KGi{cx?= NY\LNHJwSWO2aY\heIlwdiCxZjDSRXIhcW5ibX;1d4UhTjliY3XscJMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gR3lROj[DMTDtVm5CKGyndnXsJIF1KDBwMEGgeW0h[W[2ZYKgOFghcHK|IHL5JHJVNVCFUjDhcoFtgXOrcx?= MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd7OUK1O{c,OjR5OUmyOVc9N2F-
HL60 MWjGeY5kfGmxbjDhd5NigQ>? MkHKNUB2VQ>? Mn7JOEBl[Xm| M2TieGlv\HWldHnvckBw\iCUQWKtcYVlcWG2ZXSg[Iln\mW{ZX70bYF1cW:wIH;mJIh2dWGwIFjMOlAh[2WubIOgZZQhOSC3TTDh[pRmeiB2IHThfZMh[nliTlLUJIF{e2G7 NW\XcVJCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3PVkzPTdpPkK0O|k6OjV5PD;hQi=>
MDA-MB-231 M33Gcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnHOS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDifUBOXFRiYYPzZZktKEeLNUC9NVQvOTMQvF2= M1zx[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3NkO0NVMxLz5{NU[zOFE{ODxxYU6=
MDA-MB-468 NWHxfIxYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFHRUGdIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOTEFvTVKtOFY5KGOnbHzzJIJ6KE2WVDDhd5NigSxiR1m1NF0yPC5zMt88US=> MnTuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4M{SxN|AoRjJ3NkO0NVMxRC:jPh?=
SKBR3 NHe3R5FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\zO|BTT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hW0uEUkOgZ4VtdHNiYomgUXRVKGG|c3H5MEBIUTVyPUKyMlnPxE1? Ml7PQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4M{SxN|AoRjJ3NkO0NVMxRC:jPh?=
CWR22Rv1 M1q0XGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4jvSmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNYWjJ{Uo[xJINmdGy|IHL5JG1VXCCjc4PhfUwhT0l3ME2yOU4yOc7:TR?= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ|NEGzNEc,OjV4M{SxN|A9N2F-
PC3 MljCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH\uZm1Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBRSzNiY3XscJMh[nliTWTUJIF{e2G7LDDHTVUxRTN4LkROwG0> MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ|NEGzNEc,OjV4M{SxN|A9N2F-
LNCAP MnjyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFLZbIFIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBNVkODUDDj[YxteyCkeTDNWHQh[XO|YYmsJGdKPTB;NEeuPFbPxE1? MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ|NEGzNEc,OjV4M{SxN|A9N2F-
HL60 MkXDSpVv[3Srb36gZZN{[Xl? NFOzZ3oxNjFidV2= NIjJdJk4OiCqcoO= Mn\MTY5lfWO2aX;uJI9nKEO\UEK2RVEh\XiycnXzd4lwdiCrbjDoeY1idiCKTE[wJINmdGy|IHH0JFAvOSC3TTDh[pRmeiB5MjDodpM> Mon5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4OES0NlQoRjJ3Nki0OFI1RC:jPh?=
T47D NEnBVmdEgXSxdH;4bYNqfHliYYPzZZk> NIXLTGs1QCCqcoO= NWX4Znh1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXDR5RDDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OD1yLkiy{txO MnvwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV5MEGyOVEoRjJ3N{CxNlUyRC:jPh?=
MDA-MB-453 Ml;oR5l1d3SxeHnjbZR6KGG|c3H5 NWnOU2E5PDhiaILz MmPvR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUS1N{Bk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhT0l3ME25MlUy|ryP NIn4[|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUewNVI2OSd-MkW3NFEzPTF:L3G+
LNCAP MoTpR5l1d3SxeHnjbZR6KGG|c3H5 M1rPZ|Q5KGi{cx?= M13w[GN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGxPS0GSIHPlcIx{KGG|c3Xzd4VlKGG|IILl[JVkfGmxbjDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDHTVUxRTFyLkOz{txO MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyMUK1NUc,OjV5MEGyOVE9N2F-
DU145 M4ezdmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1;FXlQ5KGi{cx?= Mn7KR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVA:OTFwNkVOwG0> MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyMUK1NUc,OjV5MEGyOVE9N2F-
MCF7 NGKw[4VEgXSxdH;4bYNqfHliYYPzZZk> MXe0PEBpenN? M{LEN2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVA:OTJwM{pOwG0> NYLs[JNuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3NFEzPTFpPkK1O|AyOjVzPD;hQi=>
PC3 NHXZVFhEgXSxdH;4bYNqfHliYYPzZZk> NHH3Znc1QCCqcoO= NIrj[lREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[XO|ZYPz[YQh[XNicnXkeYN1cW:wIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVA:OTJwNkVOwG0> MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTdyMUK1NUc,OjV5MEGyOVE9N2F-
HEK293 MVPGeY5kfGmxbjDhd5NigQ>? M{\kRVAvODFidH:gNE4yKHWP NXn5doQ1PDhiaILz NHi1NWxC\2:waYP0JIFkfGm4aYT5JIF1KFKDUnHsdIhiKCi3bnvuc5dvKG:{aXfpckkh\XiycnXzd4VlKGmwIFjFT|I6OyClZXzsd{Bie3Onc4Pl[EBieyC2cnHud4NzcXC2aX;uZYwh[WO2aY\heIlwdiCjdDCwMlAyKHSxIECuNUB2VSCjZoTldkA1QCCqcoOgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7 NYX3dVR[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4N|gyPDFpPkK1PFM5OTRzPD;hQi=>
NB4 NIe1dmNCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= M2K2dlEhfU1? MVi5OkBpenN? NGDiVZBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7COEBk\WyuczDhd5Nme3OnZDDhd{Bl\WO{ZXHz[UBqdiClZXzsJJZq[WKrbHn0fUBifCBzIIXNJIFnfGW{IEm2JIhzeyCkeTD0dplx[W5iYnz1[UBmgGOudYPpc44hfGW|dB?= MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjByNUCyNkc,OjZyMEWwNlI9N2F-
HL60 NXPCXINUTnWwY4Tpc44h[XO|YYm= MUmwMlEhfG9iMUCgeW0> MUizJIRigXN? NInGVHdKdmS3Y4Tpc44hd2ZiY3XscEBlcW[oZYLlcpRq[XSrb36gbY4hcHWvYX6gTGw3OCClZXzsd{BifCByLkGgeI8hOTBidV2gcYVie3W{ZXSgZYZ1\XJiMzDkZZl{KGK7IF7CWE9OXFRiYYPzZZk> M3zaVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OEOyNlE2Lz5{NkizNlIyPTxxYU6=
HL60 MlTBSpVv[3Srb36gZZN{[Xl? NWr3fmhzOC5zIITvJFExKHWP MoPGOUBl[Xm| M{Ppfmlv\HWldHnvckBw\iClZXzsJIRq\m[ncnXueIlifGmxbjDpckBpfW2jbjDIUFYxKGOnbHzzJIF1KDBwMTD0c{AyOCC3TTDt[YF{fXKnZDDh[pRmeiB3IHThfZMh[nliTlLUM21VXCCjc4PhfS=> NYDQbXRbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[4N|IzOTVpPkK2PFMzOjF3PD;hQi=>
SH-SY5Y NULzepZLTnWwY4Tpc44h[XO|YYm= M2TMWlExKHWP MXKxNEBl[Xm| NYfMeoN5UW6mdXP0bY9vKG:oIH7leZJwdmGuIHTp[oZmemWwdHnheIlwdiCrbjDoeY1idiCVSD3TXVV[KGOnbHzzJIF{e2W|c3XkJIF{KGW6dHXud4l3\SCwZYXybZRmeyCob4LtZZRqd25iYYSgNVAhfU1iZn;scI94\WRiYomgZ5VtfHW{ZTDt[YRqfW1icnXwcIFk\W2nboSg[o9zKGW4ZYL5JJRpemWnIHThfZMh\m:{IEGwJIRigXNiYomgbY53\XK2ZXStdIhie2VibXnjdo9{[2:yaXOgZY5idHm|aYO= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDh4M{O1PEc,Ojh6NkOzOVg9N2F-
SH-SY5Y Mm[2SpVv[3Srb36gZZN{[Xl? MVmxNEB2VQ>? MYLJcoR2[3Srb36gc4YhdmW3cn;uZYwh\GmoZnXy[Y51cWG2aX;uJIlvKGi3bXHuJHNJNVO\NWmgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDDwdo9tcW[ncnH0bY9vKGG2IEGwJJVOKG[xbHzve4VlKGK7IHP1cJR2emVibXXkbZVuKHKncHzhZ4Vu\W62IH\vdkBmfmW{eTD0bJJm\SCmYYnzJIZweiBzMDDkZZl{KGK7IHnueoVzfGWmLYDoZZNmKG2rY4Lvd4NweGmlIHHuZYx6e2m| NIThTVk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEi2N|M2QCd-Mki4OlM{PTh:L3G+
SK-N-AS NGfG[phE\WyuIHP5Z4xmKGG|c3H5 NIPlXW41KHWP NVnPV2ZWfXBidH:gO|IhcHK| MV3D[YxtKGO7Y3zlJIFzemW|dDDpckBpfW2jbjDTT{1PNUGVIHPlcIx{KGG2IESgeW0hfXBidH:gO|IhcHK|IHL5JJBzd3CrZHn1cUBqd2SrZHWgd5RicW6rbnegZoF{\WRiZnzve{BkgXSxbXX0dpk> NWr2UGJ1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5Nlc4QDlpPkK4PVI4Pzh7PD;hQi=>
SK-N-AS M13pS2NmdGxiY4njcIUh[XO|YYm= M{LYTlQhfU1? M3G0WFI1KGi{cx?= MlnLR4VtdCCleXPs[UBienKnc4SgbY4hcHWvYX6gV2suVi2DUzDj[YxteyCjc4Pld5Nm\CCjczDhZ4N2dXWuYYTpc44h[XRic4XiMWcyKHCqYYPlJIF1KDRidV2gZYZ1\XJiMkSgbJJ{KGK7IIDyc5Bq\Gm3bTDpc4Rq\GVic4ThbY5qdmdiYnHz[YQh\myxdzDjfZRwdWW2com= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl{N{e4PUc,Ojh7Mke3PFk9N2F-
COS-7 MnnxSpVv[3Srb36gZZN{[Xl? MXKxJIRigQ>? MU\UdoFve2GldHn2ZZRqd25ib3[gcY92e2ViR3HsOE1nfXOnZDDSRXJo[W2vYT3MRmQh\XiycnXzd4VlKGmwIFPPV{04KGOnbHzzJIFnfGW{IEGg[IF6KGK7IHLybYdpfC2JbH:gdoVi\2WwdDDiZZNm\CCjc4PhfUwhTUN3ME2wMlAxODJ{zszN Mn:xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{OEiwO|EoRjJ7Mki4NFcyRC:jPh?=
COS-7 MXrGeY5kfGmxbjDhd5NigQ>? MmDRNUBl[Xl? M1\GR3Rz[W6|YXP0bZZifGmxbjDv[kBud3W|ZTDHZYw1NW[3c3XkJHJCWmKndHGtUGJFKGW6cILld5Nm\CCrbjDDU3MuPyClZXzsd{Bi\nSncjCxJIRigSCkeTDidolocHRvR3zvJJJm[WenboSgZoF{\WRiYYPzZZktKEWFNUC9NE4xODB3Mt88US=> NHTiRY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUK4PFA4OSd-MkmyPFgxPzF:L3G+
HEK293T MYrGeY5kfGmxbjDhd5NigQ>? MVOxOkB1dyB{NDDodpM> NUHwTWdtXHKjboPhZ5RqfmG2aX;uJI9nKGi3bXHuJGdidDRvRFLEMYZ2e2WmIGLBVoFteGijLVzCSEBmgHC{ZYPz[YQhcW5iSFXLNlk{XCClZXzsd{Bi\nSncjCxOkB1dyB{NDDodpMh[nliRmLFWEBj[XOnZDDi[ZRiNWyjY4ThcYF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7LDDFR|UxRTBwMECxNFHPxE1? M3fPU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7Mki4NFcyLz5{OUK4PFA4OTxxYU6=
COS-7 NV;6XmJVTnWwY4Tpc44h[XO|YYm= NVXkT4x2OSCmYYm= M{nyR3Rz[W6|YXP0bZZifGmxbjDv[kBud3W|ZTDHZYw1NW[3c3XkJHJCWmGucHjhMWxDTCCneIDy[ZN{\WRiaX6gR29UNTdiY3XscJMh[W[2ZYKgNUBl[XliYomgZpJq\2i2LVfsc{Bz\WGpZX70JIJie2WmIHHzd4F6NCCHQ{WwQVAvODBzNUJOwG0> NEXH[3Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUK4PFA4OSd-MkmyPFgxPzF:L3G+
OHS-50 M3v6XJFJXFNiYYPzZZk> M32yfJFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCRSGOtOVAh[2WubIO= NV\aUIh1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
TERA2.cl.SP12 MnzvSpVv[3Srb36gZZN{[Xl? MX[xNEB2VQ>? NGjLNHE4KGSjeYO= NGf4U|lKdmS3Y4Tpc44hd2ZibnX1do9v[WxiZHnm[oVz\W62aXH0bY9vKGmwIHj1cYFvKFSHUlGyMoNtNlOSMUKgZ4VtdHNiYYPz[ZN{\WRiYYOg[YZn\WO2IH;uJHNUTUF|IHX4dJJme3Orb36gZZQhOTBidV2gZYZ1\XJiNzDkZZl{KGK7IH\sc5ch[3m2b33leJJq[yCjbnHsfZNqew>? NXXVe2xORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|k6OTVpPkK5OFM6QTF3PD;hQi=>
TERA2.cl.SP12 NWjWR|RkTnWwY4Tpc44h[XO|YYm= Mnn2NVAhfU1? Mo\NO{Bl[Xm| MkTaTY5lfWO2aX;uJI9nKG6ndYLvcoFtKGSrZn\ldoVvfGmjdHnvckBqdiCqdX3hckBVTVKDMj7jcE5UWDF{IHPlcIx{KGG|c3Xzd4VlKGG|IHXm[oVkfCCxbjDUVmEyPjBiZYjwdoV{e2mxbjDheEAyOCC3TTDh[pRmeiB5IHThfZMh[nliZnzve{BkgXSxbXX0dolkKGGwYXz5d4l{ M{CwU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO5PVE2Lz5{OUSzPVkyPTxxYU6=
TERA2.cl.SP12 MkP1SpVv[3Srb36gZZN{[Xl? Mn;ZNVAhfU1? MlPOO{Bl[Xm| NUfiRWd5UW6mdXP0bY9vKG:oIH7leZJwdmGuIHTp[oZmemWwdHnheIlwdiCrbjDoeY1idiCWRWLBNk5kdC6VUEGyJINmdGy|IHHzd4V{e2WmIHHzJIVn\mWldDDvckBCOkJ3IHX4dJJme3Orb36gZZQhOTBidV2gZYZ1\XJiNzDkZZl{KGK7IH\sc5ch[3m2b33leJJq[yCjbnHsfZNqew>? NXLiXocyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|k6OTVpPkK5OFM6QTF3PD;hQi=>
TERA2.cl.SP12 NH3IfFNHfW6ldHnvckBie3OjeR?= NH61WFUyOCC3TR?= M2nXSFch\GG7cx?= MoLITY5lfWO2aX;uJI9nKG6ndYLvcoFtKGSrZn\ldoVvfGmjdHnvckBqdiCqdX3hckBVTVKDMj7jcE5UWDF{IHPlcIx{KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJGEzSjViZYjwdoV{e2mxbjDheEAyOCC3TTDt[YF{fXKnZDDh[pRmeiB5IHThfZMh[nliaX3teY5w\my3b4Lld4NmdmOnIH3leIhw\A>? Ml;3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{m5NVUoRjJ7NEO5PVE2RC:jPh?=
TERA2.cl.SP12 MXHGeY5kfGmxbjDhd5NigQ>? MoPUNVAhfU1? NHX5[4xKdmS3Y4Tpc44hd2ZibnX1do9v[WxiZHnm[oVz\W62aXH0bY9vKGmwIHj1cYFvKFSHUlGyMoNtNlOSMUKgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hXFWMMTDlfJBz\XO|aX;uJIF1KDFyIIXNJI1m[XO3cnXkJJVxKHSxIEOge4Vmc3NiYomgbY1ufW6xZnz1c5Jme2OnbnPlJI1mfGixZB?= NF;VfXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzPVkyPSd-Mkm0N|k6OTV:L3G+
SH-SY5Y NXTwT4VkTnWwY4Tpc44h[XO|YYm= NITt[IoyOCC3TR?= NEn0fVY1KHSxIEGyJIhzew>? MWrJcoR2[3Srb36gc4YhdmW3cn;uZYwh\GmoZnXy[Y51cWG2aX;uJIlvKGi3bXHuJHNJNVO\NWmgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hWkGUYnX0ZUBuWk6DIHX4dJJme3Orb36gZZQhOTBidV2gcYVie3W{ZXSgZYZ1\XJiNDD0c{AyOiCqcoOgZpkhWlRvUFPSJIFv[Wy7c3nz NVPRRlF5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|k6OTVpPkK5OFM6QTF3PD;hQi=>
SH-SY5Y Ml\ISpVv[3Srb36gZZN{[Xl? MnrDNVAhfU1? Mlv4OEB1dyBzMjDodpM> NWCy[3hNXHKjboPhZ5RqfmG2aX;uJI9nKFKDUnLleIEhcW5iaIXtZY4hW0hvU2m1XUBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCFWWCyOmEyKG2UTlGg[ZhxemW|c3nvckBifCBzMDD1UUBu\WG|dYLl[EBi\nSncjC0JJRwKDF{IHjyd{BjgSCUVD3QR3Ih[W6jbInzbZM> MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR|OUmxOUc,Ojl2M{m5NVU9N2F-
SH-SY5Y NXXjTItSTnWwY4Tpc44h[XO|YYm= MWCwMlAxOSC2bzCxJJVO M2TMelghcHK| Mlq3TY5lfWO2aX;uJI9nKG6ndYLvcoFtKGSrZn\ldoVvfGmjdHnvckBqdiCqdX3hckBUUC2VWUXZJINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKFKDUnLleIEhdVKQQTDlfJBz\XO|aX;uJIF1KDBwMECxJJRwKDFidV2gcYVie3W{ZXSgZYZ1\XJiODDodpMh[nliUmStVGNTKGGwYXz5d4l{ MkntQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{m5NVUoRjJ7NEO5PVE2RC:jPh?=
SH-SY5Y M3rZeGZ2dmO2aX;uJIF{e2G7 M4LvVFAvODBzIITvJFEhfU1? NV3BSGRRQCCqcoO= M2G3VHRz[W6|YXP0bZZifGmxbjDv[kBTSVKkZYThJIlvKGi3bXHuJHNJNVO\NWmgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hS1mSMk\BNUBuWk6DIHX4dJJme3Orb36gZZQhOC5yMEGgeI8hOSC3TTDt[YF{fXKnZDDh[pRmeiB6IHjyd{BjgSCUVD3QR3Ih[W6jbInzbZM> NInlblU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzPVkyPSd-Mkm0N|k6OTV:L3G+
COS-7 MorISpVv[3Srb36gZZN{[Xl? MVyyOEBpenN? NIT0b3JVemGwc3HjeIl3[XSrb36gc4YhT0GOND3meZNm\CCvb4Xz[UBTSVKpYX3tZU1NSkRiZYjwdoV{e2WmIHnuJGNQWy15IHPlcIx{KGGodHXyJFI1KGi{czDifUBjemmpaIStS4xwKHKnYXflcpQh[mG|ZXSgZZN{[XluIFXDOVA:OC5yMEC2{txO MoSyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB5OUKwN|goRjNyN{myNFM5RC:jPh?=
COS-7 MXjGeY5kfGmxbjDhd5NigQ>? M1LpU|I1KGi{cx?= M4TldnRz[W6|YXP0bZZifGmxbjDv[kBISUx2LX\1d4VlKG2xdYPlJHJCWmGucHjhMWxDTCCneIDy[ZN{\WRiaX6gR29UNTdiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JIJzcWeqdD3HcI8hemWjZ3XueEBj[XOnZDDhd5NigSxiRVO1NF0xNjByMUNOwG0> NGPDfpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEe5NlA{QCd-M{C3PVIxOzh:L3G+
COS-7 MUDGeY5kfGmxbjDhd5NigQ>? NFrvdI4zPCCqcoO= Ml\tWJJidnOjY4TpeoF1cW:wIH;mJGdCVDRvZoXz[YQhdW:3c3WgVmFT[mW2YT3MRmQh\XiycnXzd4VlKGmwIFPPV{04KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDidolocHRvR3zvJJJm[WenboSgZoF{\WRiYYPzZZktKEWFNUC9NE4xODF{zszN Mk\2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB5OUKwN|goRjNyN{myNFM5RC:jPh?=
HL60 MkPtSpVv[3Srb36gZZN{[Xl? NInoTVkyOCC2bzCzNEB2VQ>? M{CySlYh\GG7cx?= MofoTY5lfWO2aX;uJI9nKGe{YX71cI9kgXSrYzDkbYZn\XKnboTpZZRqd25iaX6gbJVu[W5iSFy2NEBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCFREGxZk1CWENvQ4m3JJBwe2m2aY\lJINmdGy|IHH0JFExKHSxIEOwJJVOKGGodHXyJFYh\GG7czDifUBndG:5IHP5eI9u\XS{eTDhcoFtgXOrcx?= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODl{NUOzPEc,OzB7MkWzN|g9N2F-
HL60 MkDkRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? M{LCW|EhfG9iM{CgeW0> NEnQR2k{KGSjeYO= MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiONkCgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKH[rYXLpcIl1gSCjdDCxJJRwKDNyIIXNJIFnfGW{IEOg[IF6eyCkeTDTVmIh[XO|YYm= NYroO|F3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
NB4 NVu4cmg5SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MnzNNUB1dyB|MDD1US=> NYPrRoc2OyCmYYnz NWPvSGNmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDORlQh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwII\pZYJqdGm2eTDheEAyKHSxIEOwJJVOKGGodHXyJFMh\GG7czDifUBUWkJiYYPzZZk> NXy2[2R6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
HL60 NVfIOlYxTnWwY4Tpc44h[XO|YYm= NFrNRZU{OCC3TR?= NHjaUlg4OiCqcoO= MVfJcohq[mm2aX;uJI9nKGOxbH;ufUBnd3KvYYTpc44hcW5iaIXtZY4hUEx4MDDj[YxteyCjdDCzNEB2VSCycnXpcoN2[mG2ZXSg[o9zKDd{IHjyd{Bnd2yub4fl[EBjgSClb33wc5Vv\CC5YYPoc5V1KGGwZDDt[YF{fXKnZDDh[pRmeiB5IITvJFExKGSjeYO= M2O0SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyOUK1N|M5Lz5|MEmyOVM{QDxxYU6=
NB4 NVXBZVhUTnWwY4Tpc44h[XO|YYm= NEC3PJk{OCC3TR?= MVG3NkBpenN? NHe1bpJKdmirYnn0bY9vKG:oIHPvcI9vgSCob4LtZZRqd25iaX6gbJVu[W5iTlK0JINmdGy|IHH0JFMxKHWPIIDy[Ylv[3WkYYTl[EBnd3JiN{KgbJJ{KG[xbHzve4VlKGK7IHPvcZBwfW6mIIfhd4hwfXRiYX7kJI1m[XO3cnXkJIFnfGW{IEegeI8hOTBiZHH5dy=> M2fiOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyOUK1N|M5Lz5|MEmyOVM{QDxxYU6=
NB4 M2LmeWZ2dmO2aX;uJIF{e2G7 MnfTNVAhfG9iM{CgeW0> NFLSc3k3KGSjeYO= NH;L[29KdmS3Y4Tpc44hd2ZiZ4LhcpVtd2O7dHnjJIRq\m[ncnXueIlifGmxbjDpckBpfW2jbjDORlQh[2WubIOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iQ1SxNYIuSVCFLVP5O{Bxd3OrdHn2[UBk\WyuczDheEAyOCC2bzCzNEB2VSCjZoTldkA3KGSjeYOgZpkh\myxdzDjfZRwdWW2comgZY5idHm|aYO= NV75UVVPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
HL60 Mn\OSpVv[3Srb36gZZN{[Xl? NE\CSmcyOCC2bzCzNEB2VQ>? Ml;tOkBl[Xm| M{jFS2lv\HWldHnvckBw\iCpcnHueYxw[3m2aXOg[Iln\mW{ZX70bYF1cW:wIHnuJIh2dWGwIFjMOlAh\3KjboXsc4N6fGmlIHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEOGMUHjMWFRSyCyb4PpeIl3\SClZXzsd{BifCBzMDD0c{A{OCC3TTDh[pRmeiB4IHThfZMh[nliZnzve{BkgXSxbXX0dpkh[W6jbInzbZM> NVTZfmNRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
NB4 MlH4SpVv[3Srb36gZZN{[Xl? M2HpdVExKHSxIEOwJJVO NWPySlQxPiCmYYnz NXXpVYZYUW6mdXP0bY9vKG:oIHfyZY52dG:leYTpZ{BlcW[oZYLlcpRq[XSrb36gbY4hcHWvYX6gUmI1KGOnbHzzJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIFPENVFkNUGSQzDwc5NqfGm4ZTDj[YxteyCjdDCxNEB1dyB|MDD1UUBi\nSncjC2JIRigXNiYomg[oxwfyCleYTvcYV1enliYX7hcJl{cXN? NVzBW|dWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
HL60 MXvGeY5kfGmxbjDhd5NigQ>? NFjVe4MyOCC2bzCzNEB2VQ>? NXv5PGFUPiCmYYnz M4XZeWlv\HWldHnvckBw\iCpcnHueYxw[3m2aXOg[Iln\mW{ZX70bYF1cW:wIHnuJIh2dWGwIFjMOlAh[2WubIOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iQ1SxOE1HUVSFIIDvd4l1cX[nIHPlcIx{KGG2IEGwJJRwKDNyIIXNJIFnfGW{IE[g[IF6eyCkeTDmcI94KGO7dH;t[ZRzgSCjbnHsfZNqew>? NVP6fpZmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
NB4 NEjIS3BHfW6ldHnvckBie3OjeR?= MmP2NVAhfG9iM{CgeW0> MmXnOkBl[Xm| NV;o[VFUUW6mdXP0bY9vKG:oIHfyZY52dG:leYTpZ{BlcW[oZYLlcpRq[XSrb36gbY4hcHWvYX6gUmI1KGOnbHzzJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIFPENVQheG:|aYTpeoUh[2WubIOgZZQhOTBidH:gN|AhfU1iYX\0[ZIhPiCmYYnzJIJ6KE[LVFOgd5RicW6rbnegZoF{\WRiZnzve{BkgXSxbXX0dpkh[W6jbInzbZM> NXSweoQ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5NlU{OzhpPkOwPVI2OzN6PD;hQi=>
SH-SY5Y NIrwUmRHfW6ldHnvckBie3OjeR?= NVTXd|ZEOTBidV2= NULRWpdXOjRiaILz NX6z[nJQUW6mdXP0bY9vKG:oIH7leZJw\2WwZYPpd{BqdiCqdX3hckBUUC2VWUXZJINmdGy|IHHzd4V{e2WmIHHzJJVxemWpdXzheIlwdiCxZjDHRXA1OyCvUl7BJIF1KDFyIIXNJIlv[3WkYYTl[EBnd3JiMkSgbJJ{KGK7IGLUMXBEWiCjbnHsfZNqew>? NX;2c3d3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C5PVY4QDFpPkOwPVk3PzhzPD;hQi=>
SH-SY5Y NYrRVmc4TnWwY4Tpc44h[XO|YYm= MUCxNEB2VQ>? MWOyOEBpenN? NYrhWoNpUW6mdXP0bY9vKG:oIH7leZJw\2WwZYPpd{BqdiCqdX3hckBUUC2VWUXZJINmdGy|IHHzd4V{e2WmIHHzJJVxemWpdXzheIlwdiCxZjDOMY16[yCvUl7BJIF1KDFyIIXNJIlv[3WkYYTl[EBnd3JiMkSgbJJ{KGK7IGLUMXBEWiCjbnHsfZNqew>? MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODl7Nke4NUc,OzB7OU[3PFE9N2F-
SH-SY5Y MUnGeY5kfGmxbjDhd5NigQ>? MX[xNEB2VQ>? MYqyOEBpenN? M1TCc2lv\HWldHnvckBw\iCwZYXyc4dmdmW|aYOgbY4hcHWvYX6gV2guW1l3WTDj[YxteyCjc4Pld5Nm\CCjczD1dJJm\3WuYYTpc44hd2ZiTVHQMVIhdVKQQTDheEAyOCC3TTDpcoN2[mG2ZXSg[o9zKDJ2IHjyd{BjgSCUVD3QR3Ih[W6jbInzbZM> M3PUW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyOUm2O|gyLz5|MEm5Olc5OTxxYU6=
SH-SY5Y MoPySpVv[3Srb36gZZN{[Xl? NVnvU3o{OTBidV2= MYG3NkBpenN? M4LpWWlv\HWldHnvckBw\iCwZYXyc4dmdmW|aYOgbY4hcHWvYX6gV2guW1l3WTDj[YxteyCjc4Pld5Nm\CCjczDzeIlufWyjdHnvckBw\iCwZYXybZRmKG:3dHfyc5d1cCCjdDCxNEB2VSCrbnP1ZoF1\WRiZn;yJFczKGi{czDifUBxcGG|ZTDjc451emG|dDDtbYNzd3Olb4DpZ{BidmGueYPpdy=> M2ntUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyOUm2O|gyLz5|MEm5Olc5OTxxYU6=
HL60 NF\1TFdHfW6ldHnvckBie3OjeR?= MkS3NkB2VQ>? NGn3SoY1QCCqcoO= MVfJcoR2[3Srb36gc4Yh\GmoZnXy[Y51cWG2aX;uJIlvKGi3bXHuJGhNPjBiY3XscJMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gR2QyOWJicH;zbZRqfmViY3XscJMh[XRiMjD1UUBqdmO3YnH0[YQh\m:{IES4JIhzeyCkeTC3MWFCTCC|dHHpcolv\y2kYYPl[EBndG:5IHP5eI9u\XS{aXOgZY5idHm|aYO= M2\rc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNzNEC4PFA6Lz5|MUSwPFgxQTxxYU6=
CV-1 MmHkSpVv[3Srb36gZZN{[Xl? NUjWV|BsS2:vcH;1coQhf2G|IITld5Rm\CCob4Kg[pVv[3Srb37hcEBi[3Srdnn0fUBqdiCFVj2xJINmdGy|IITyZY5{\mWldHXkJJdqfGhiYX6g[ZhxemW|c3nvckB3\WO2b4Kg[o9zKHKndHnuc4lkKGGlaXSgdoVk\XC2b4Kg[4FudWFidYPpcochfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR|UxRTBwMECwO:69VQ>? M1G3dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-Q3jFUWJNRC:jPh?=
CV-1 Mn[3SpVv[3Srb36gZZN{[Xl? NIfBVGNEd22yb4Xu[EB4[XNidHXzeIVlKG[xcjDmeY5kfGmxbnHsJIFkfGm4aYT5JIlvKEOYLUGgZ4VtdHNidILhcpNn\WO2ZXSge4l1cCCjbjDlfJBz\XO|aX;uJJZm[3SxcjDmc5IhemW2aX7vbYMh[WOrZDDy[YNmeHSxcjDi[ZRiKHW|aX7nJJRz[W6|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjByMd88US=> M2Oyd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-Q3jFUWJNRC:jPh?=
CV-1 M3jJb2Z2dmO2aX;uJIF{e2G7 NYD2ZWVTS2:vcH;1coQhf2G|IITld5Rm\CCob4Kg[pVv[3Srb37hcEBi[3Srdnn0fUBqdiCFVj2xJINmdGy|IITyZY5{\mWldHXkJJdqfGhiYX6g[ZhxemW|c3nvckB3\WO2b4Kg[o9zKHKndHnuc4lkKGGlaXSgdoVk\XC2b4KgZYxxcGFidYPpcochfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR|UxRTBwMEC3{txO NUjaeXJXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7DbGVOSkx:L3G+
F9 MYjGeY5kfGmxbjDhd5NigQ>? MXrD[YxtfWyjcjDhZ5Rqfmm2eTDvckB1cGViZHnm[oVz\W62aXH0bY9vKHejczDxeYFvfGmoaXXkJIJ6KG2nYYP1doUhd2ZicHzhd41qdm:pZX6gZYN1cX[jdH;yJIlvKG2xdYPlJIVu[nK7b37hcEB1\XKjdH;jZZJkcW6xbXGgSlkh[2WubIOsJGFEPTB;MD6y{txO M1zNUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-Q3jFUWJNRC:jPh?=
CV-1 Mnj2SpVv[3Srb36gZZN{[Xl? M1LoUGNwdXCxdX7kJJdieyC2ZYP0[YQh\m:{IH\1coN1cW:wYXygZYN1cX[rdImgbY4hS1ZvMTDj[YxteyC2cnHud4Zm[3SnZDD3bZRpKGGwIHX4dJJme3Orb36geoVkfG:{IH\vdkBz\XSrbn;p[EBZKHKnY3XweI9zKGGucHjhJJV{cW6pIITyZY5{[WO2aY\heIlwdiCjc4PhfUwhTUN3ME2wMlnPxE1? MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRkOqRV3CUFww[T5?
CV-1 M1jNXmZ2dmO2aX;uJIF{e2G7 Mn[3R49ueG:3bnSge4F{KHSnc4Tl[EBnd3JiZoXuZ5Rqd26jbDDhZ5Rqfmm2eTDpckBEXi1zIHPlcIx{KHS{YX7z[oVkfGWmIIfpeIgh[W5iZYjwdoV{e2mxbjD2[YN1d3JiZn;yJJJmfGmwb3nkJHghemWlZYD0c5Ih\2GvbXGgeZNqdmdidILhcpNi[3SrdnH0bY9vKGG|c3H5MEBGSzVyPUGuNe69VQ>? NHPI[Xk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPlPoSW1DVDxxYU6=
CV-1 MXzGeY5kfGmxbjDhd5NigQ>? M1zp[2NwdXCxdX7kJJdieyC2ZYP0[YQh\m:{IH\1coN1cW:wYXygZYN1cX[rdImgbY4hS1ZvMTDj[YxteyC2cnHud4Zm[3SnZDD3bZRpKGGwIHX4dJJme3Orb36geoVkfG:{IH\vdkBz\XSrbn;p[EBZKHKnY3XweI9zKGKndHGgeZNqdmdidILhcpNi[3SrdnH0bY9vKGG|c3H5MEBGSzVyPUGuOO69VQ>? MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRkOqRV3CUFww[T5?
MV-4-11 MkTOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIPTZotKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB{MEm5{txO M4HpTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
ATN-1 MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYW1R4xbUW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODNyM988US=> M3e0NVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
MC-IXC NYjxcGtiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4TYc2lvcGmkaYTpc44hd2ZiaIXtZY4hVUNvSWjDJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPTR|Nt88US=> MlzhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
HH MlzPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXXJcohq[mm2aX;uJI9nKGi3bXHuJGhJKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zOUW1OO69VQ>? Mmj1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
NB13 MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXLuOJNuUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zPTZ4NN88US=> M3HrVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
D-283MED MnnBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIHQTHBKdmirYnn0bY9vKG:oIHj1cYFvKERvMkizUWVFKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5{OEK2Nu69VQ>? M3HGeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
HL-60 NYfCPWk2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnrqTY5pcWKrdHnvckBw\iCqdX3hckBJVC14MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlg1QTIQvF2= NWD1PHdXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
EW-3 NWLYWWRtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlPUTY5pcWKrdHnvckBw\iCqdX3hckBGXy1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD60PFAzQM7:TR?= NUjiS2xyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
KU812 M13ORmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmTETY5pcWKrdHnvckBw\iCqdX3hckBMXThzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVM3ODoQvF2= NX;UVYxrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
SK-NEP-1 M4DUZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFPy[FBKdmirYnn0bY9vKG:oIHj1cYFvKFONLV7FVE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54NkKzNe69VQ>? Mnj4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
HCC1806 NFn4dW1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHW4N|FKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G4NFYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjd{OUK5{txO MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
HuO-3N1 NGHkbYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mmi2TY5pcWKrdHnvckBw\iCqdX3hckBJfU9vM16xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45OzF4zszN Mnq2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
CTV-1 NWn5OWlST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7CbFVKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46PjJ6Mt88US=> NH3ZR|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
RPMI-8226 MnG4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUOxOXlFUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVgzOjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm5N|M1|ryP MkTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
LAMA-84 MnnCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3TYNGlvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQTl4M{ZOwG0> MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
NCI-H720 MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXzJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{KwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xOjZ{Md88US=> MkP2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
MOLT-13 MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGrYUW9KdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStNVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjF2Nd88US=> MoDCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
JVM-2 MkPwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mo\wTY5pcWKrdHnvckBw\iCqdX3hckBLXk1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVc{OTcQvF2= MlXpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
NBsusSR NF7JW45Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVexcmZKUW6qaXLpeIlwdiCxZjDoeY1idiCQQoP1d3NTKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52NEm4O:69VQ>? NWPmfW5mRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
BV-173 NIXnOnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWX4d29qUW6qaXLpeIlwdiCxZjDoeY1idiCEVj2xO|Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjV7NkK2{txO NF:0VlU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
CTB-1 NHjXd|RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEP5R2ZKdmirYnn0bY9vKG:oIHj1cYFvKEOWQj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43ODN6Od88US=> M17MN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
ACN MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3[0c2lvcGmkaYTpc44hd2ZiaIXtZY4hSUOQIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT62OFk6Qc7:TR?= M1XWZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
L-363 Ml7BS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;NfWlvcGmkaYTpc44hd2ZiaIXtZY4hVC1|NkOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlA3QTZ2zszN NVnCTGRyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NCI-H69 M2rs[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml:4TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSE[5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4zPjV4Md88US=> NUDtXnI4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
ECC10 NGDLO|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUPJcohq[mm2aX;uJI9nKGi3bXHuJGVESzFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6zPFA2Os7:TR?= M{LsS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
NCI-H209 NX3ibm11T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml[xTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPTJzM{NOwG0> MnnUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
KARPAS-45 NYjaNmRGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1zhWWlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQ2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi53OUW4Ne69VQ>? MofiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
COR-L88 M4PNbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2rqcGlvcGmkaYTpc44hd2ZiaIXtZY4hS0:ULVy4PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvQDV6N{NOwG0> M2Pie|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
ML-2 M3zIVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mnr5TY5pcWKrdHnvckBw\iCqdX3hckBOVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND6wNFQ{Qc7:TR?= M4fObFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
U-266 NUH3NYRYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mmq4TY5pcWKrdHnvckBw\iCqdX3hckBWNTJ4NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuNVE5OjoQvF2= MkDJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
RS4-11 MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGjoXIlKdmirYnn0bY9vKG:oIHj1cYFvKFKVND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvPDR5M{hOwG0> Mkf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
DB MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYDNbWdIUW6qaXLpeIlwdiCxZjDoeY1idiCGQjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuO|Y2OToQvF2= NF6y[GU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
EM-2 NFfJc|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M13KNWlvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuN|I5OTIQvF2= MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
KY821 NHvDUoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWXhT41KUW6qaXLpeIlwdiCxZjDoeY1idiCNWUiyNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPzB2MkdOwG0> NVXER|B6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
QIMR-WIL M33pOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkfLTY5pcWKrdHnvckBw\iCqdX3hckBSUU2ULWfJUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPjF3Nd88US=> M3WyS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
KYSE-180 MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIj0fG5KdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtNVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi55MEG0{txO MmTXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
ALL-PO MmS0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmOyTY5pcWKrdHnvckBw\iCqdX3hckBCVExvUF:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22Mlg4PDYQvF2= MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
NB14 NGXjco5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVLJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkGyO|HPxE1? NHrDXHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
BPH-1 NUnxNI9CT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnjrTY5pcWKrdHnvckBw\iCqdX3hckBDWEhvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuOFM3OTIQvF2= NYP1b3FQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
A3-KAW NFjRbHVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX;vPIszUW6qaXLpeIlwdiCxZjDoeY1idiCDMz3LRXch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjV7NkO3{txO MkD0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
EW-13 M1\CN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFzXO|FKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43OTB5ON88US=> NGXxWIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
NCI-H526 NVKyT2h1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFqxOGRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py54OEK5Ne69VQ>? NUnvdnp{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NKM-1 NWDF[XRFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;O[2lvcGmkaYTpc44hd2ZiaIXtZY4hVkuPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlQyODB7zszN MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
SCC-15 NHXwe5ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYjsZWt4UW6qaXLpeIlwdiCxZjDoeY1idiCVQ1OtNVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF06NjN2N{[y{txO NICwdJA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
MEG-01 M2P1[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGW4WFBKdmirYnn0bY9vKG:oIHj1cYFvKE2HRz2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPjF|MUlOwG0> NF;te4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
NCI-H1648 M3XjZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV25[2kzUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE3PDhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkezOlE4|ryP MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
GP5d MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2DseGlvcGmkaYTpc44hd2ZiaIXtZY4hT1B3ZDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlI3OzgQvF2= NUXUbJVyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
HCC2218 M2PXTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3L0Z2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkKxPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjN6N{NOwG0> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
KE-37 Mm\qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2TkPGlvcGmkaYTpc44hd2ZiaIXtZY4hU0VvM{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE44PTF3zszN M3rYPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
CHP-212 NHT1dnRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1vxbmlvcGmkaYTpc44hd2ZiaIXtZY4hS0iSLUKxNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjh2OUVOwG0> MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
NOMO-1 NFLPUHhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHz3SY9KdmirYnn0bY9vKG:oIHj1cYFvKE6RTV:tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjl4M{VOwG0> NE\0UWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
NCI-H292 NG\FUpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVvJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkmyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOjB5Mt88US=> MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
IGROV-1 MoTxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3r1SmlvcGmkaYTpc44hd2ZiaIXtZY4hUUeUT2[tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjF|OEJOwG0> NGTHWZQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
MS-1 NXKy[4xvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUHreYZLUW6qaXLpeIlwdiCxZjDoeY1idiCPUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVQvPTV|Od88US=> M1:0fFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
KMOE-2 NXflNWRKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkPPTY5pcWKrdHnvckBw\iCqdX3hckBMVU:HLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE44QDh5zszN MlTiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
HCC1419 M361OWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFq0ZW1KdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G0NVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS5{NUG5{txO MoLQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
NCI-H1092 NWTk[21UT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGXD[GRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVA6OiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF3LkK4PVTPxE1? MlHhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
DEL NH;iT5lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGRGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF3LkO3NljPxE1? NHK5Z2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
P12-ICHIKAWA M1PHUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWLJcohq[mm2aX;uJI9nKGi3bXHuJHAyOi2LQ1jJT2FYSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF4LkS5N:69VQ>? M1jsb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
NCI-H1770 NETMcFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn\XTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG3O|Ah[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPi57MEW4{txO MkfBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
NCI-H82 MnXlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF3SbmRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IPFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPi57MkKx{txO M4LK[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
COLO-684 NUi2OlJoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEXoTY1KdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tOlg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTZwOUK3N:69VQ>? NHfNT4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
697 NFj1R|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXvydGM2UW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{45QToQvF2= NFS2VWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
HC-1 M{PnOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGhENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zOD60N|Q2|ryP M3;nOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
HSC-3 NHjpOJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVnRSW9TUW6qaXLpeIlwdiCxZjDoeY1idiCKU1OtN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njd{MUJOwG0> M4LaVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
ES3 NXTDcVF5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIe5NYpKdmirYnn0bY9vKG:oIHj1cYFvKEWVMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG4Mlg1QTYQvF2= M1nrcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
HuO9 NILaemdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1KwS2lvcGmkaYTpc44hd2ZiaIXtZY4hUHWROTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG5MlMyPTkQvF2= MnfMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
ME-180 MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFfzcmRKdmirYnn0bY9vKG:oIHj1cYFvKE2HLUG4NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE6Njh5MUROwG0> NH;MSHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
KG-1 NULycIdJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPmeolKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPU45Pzd3zszN M2fIPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
OAW-28 NHq5epRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7TeWRKdmirYnn0bY9vKG:oIHj1cYFvKE:DVz2yPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjN|MkJOwG0> M1nXTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
COLO-829 NUXkV|V5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYm5fnZmUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVgzQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJyLkOzOVPPxE1? MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
SK-N-AS NF73WJRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vQWOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNE41QTN5zszN NXSz[FZHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
KNS-42 Mlr4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{L5WWlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUSyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR6ON88US=> MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
SW13 MnK3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXrOTodRUW6qaXLpeIlwdiCxZjDoeY1idiCVV{GzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlEvPDV3ON88US=> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
J-RT3-T3-5 MlnQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVPJcohq[mm2aX;uJI9nKGi3bXHuJGouWlR|LWSzMVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOS56MEi3{txO MkjIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
KYSE-450 MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHT3cG9KdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtOFUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjFwOESzNe69VQ>? MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
CHL-1 MlnrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH\jTXdKdmirYnn0bY9vKG:oIHj1cYFvKEOKTD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOTJ2Mt88US=> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
CAKI-1 NH3mOpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYjJcohq[mm2aX;uJI9nKGi3bXHuJGNCU0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKyMlE3Qc7:TR?= MlrwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
UM-UC-3 MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVzJcohq[mm2aX;uJI9nKGi3bXHuJHVONVWFLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk43PzgQvF2= MmjoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
JVM-3 MoXTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHLyboFKdmirYnn0bY9vKG:oIHj1cYFvKEqYTT2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQTd|M988US=> NV3hbIRoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
LB1047-RCC NGnmdplIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGTPT3FKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz6wNVMz|ryP NIfHcWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
LU-139 NXLL[ZJJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlIxODQQvF2= NYOzUIhHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
SK-MEL-1 NXi2O29ET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF62SFJKdmirYnn0bY9vKG:oIHj1cYFvKFONLV3FUE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjNwNEm5Pe69VQ>? MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
SK-MEL-24 NVjUeZNlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVHDWWRNUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NSWwuOjRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Nj6wNFMz|ryP M4rOOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
A4-Fuk NUfBXHBFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH;aVGFKdmirYnn0bY9vKG:oIHj1cYFvKEF2LV\1b{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI3Njd{MUlOwG0> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
CAMA-1 MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEP3eGlKdmirYnn0bY9vKG:oIHj1cYFvKEODTVGtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI5NjBzN{pOwG0> NXnadXZHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NCI-H1623 MmrUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFX4dG9KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVYzOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ6LkG3PVbPxE1? NX;VRoE{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
A673 NX;NbXN7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVLJcohq[mm2aX;uJI9nKGi3bXHuJGE3PzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{OD6yOFQ3|ryP MkO2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
A549 MoXOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NY\zVYZvUW6qaXLpeIlwdiCxZjDoeY1idiCDNUS5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvODR4zszN NWK4TIVGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
Ramos-2G6-4C10 NXn0cmFMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\PeZo5UW6qaXLpeIlwdiCxZjDoeY1idiCUYX3vd{0zTzZvNFOxNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI6Njl6OUROwG0> MkPaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
DOHH-2 NGDVOphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWLJcohq[mm2aX;uJI9nKGi3bXHuJGRQUEhvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOwMlU{QDoQvF2= MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
CCRF-CEM M3qyZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXf3S5B2UW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNzLk[2O|PPxE1? MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
DoTc2-4510 MlTVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHvsSpBKdmirYnn0bY9vKG:oIHj1cYFvKESxVHOyMVQ2OTBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|MT65NlE6|ryP M3vzWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
A2780 MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFr6d3NKdmirYnn0bY9vKG:oIHj1cYFvKEF{N{iwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvPTV3Nd88US=> NWTrZWdiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NTERA-S-cl-D1 MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWX2VXI5UW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvQDFyNt88US=> NIjiVlQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
Mewo M1HsPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn7mTY5pcWKrdHnvckBw\iCqdX3hckBO\XexIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{OuPFQ1Ps7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
BALL-1 MkHaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYf0XHg4UW6qaXLpeIlwdiCxZjDoeY1idiCEQVzMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC5yNEW5{txO M2HOO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
A204 NGPQR3pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYTsbHF[UW6qaXLpeIlwdiCxZjDoeY1idiCDMkC0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|QvOzV|Md88US=> NXq2bHc4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
KYSE-510 MlnIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHX6eHBKdmirYnn0bY9vKG:oIHj1cYFvKEu\U1WtOVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwNUOzOe69VQ>? NU\QNIZ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
MSTO-211H NHfmZ4hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjhzN{hOwG0> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
SK-LU-1 M36yW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2f3bmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTGWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1Njh|MUZOwG0> MmTlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
EGI-1 NFnMfINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3u3NmlvcGmkaYTpc44hd2ZiaIXtZY4hTUeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU4zQTF6zszN NHvrSWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
SK-MEL-28 MmK2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3;vVWlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTVXMMVI5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzVwM{W2Pe69VQ>? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
RH-1 M3nONGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{\zZWlvcGmkaYTpc44hd2ZiaIXtZY4hWkhvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO2MlE6OTYQvF2= NWXxRmNYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
LU-134-A NHXqZ2tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4L6V2lvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO0MWEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Pi54M{mx{txO NXTGeI11RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
KS-1 MnXmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3y5ZmlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO3MlY4QTUQvF2= NYfYS5IzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
GAMG NEPvZotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHntS45KdmirYnn0bY9vKG:oIHj1cYFvKEeDTVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zO{45OjV2zszN NX;yXVM{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
TE-5 MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnjlTY5pcWKrdHnvckBw\iCqdX3hckBVTS13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNlc3P87:TR?= NXvnbpBPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
P30-OHK M1vVbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVnPXlZWUW6qaXLpeIlwdiCxZjDoeY1idiCSM{CtU2hMKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzlwNkCwOe69VQ>? M1TWc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
GOTO MljsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXPUbWs5UW6qaXLpeIlwdiCxZjDoeY1idiCJT2TPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvQDR3zszN M170fFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
Calu-6 NEPvO45Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5Mlg4|ryP MnXRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
KYSE-410 MoP5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33LRmlvcGmkaYTpc44hd2ZiaIXtZY4hU1mVRT20NVAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{QS56N{O0{txO MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
CAL-72 MlzYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2\wbGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUeyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvQDl5M988US=> M2PSeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
AM-38 NXjT[mxIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlfiTY5pcWKrdHnvckBw\iCqdX3hckBCVS1|ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSwMlMxQDUQvF2= NXrB[WtURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
BT-549 Mlv1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2nRR2lvcGmkaYTpc44hd2ZiaIXtZY4hSlRvNUS5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFAvPDZ4Nd88US=> NFjLOVg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
23132-87 NV\wc4tiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWnEd3BFUW6qaXLpeIlwdiCxZjDoeY1idiB{M{GzNk05PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRyLkW0Ne69VQ>? NInMT4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
SCC-4 MoH0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXTJcohq[mm2aX;uJI9nKGi3bXHuJHNESy12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NECuPVc5QM7:TR?= M1S2c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
LU-135 M1fwemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3XmOmlvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFEvODRzON88US=> MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyzPE8oRlODTlfFVlww[T5?
NB10 NYiyU2d4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkLCTY5pcWKrdHnvckBw\iCqdX3hckBPSjFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEGuOFg2Qc7:TR?= NWfiVFBLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NB7 MkTXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXKxVZV2UW6qaXLpeIlwdiCxZjDoeY1idiCQQkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU43ODB2zszN M{\FXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
RPMI-7951 NVn4SIJUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEPkPHRKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtO|k2OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRzLk[wNFbPxE1? Mkm0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
AU565 NXzJZ2dbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYKz[2pVUW6qaXLpeIlwdiCxZjDoeY1idiCDVUW2OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQyNjd3MkNOwG0> MmDPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
HCE-4 NIj6[JhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUfJcohq[mm2aX;uJI9nKGi3bXHuJGhETS12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuOVQ5|ryP MlvrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
BE-13 MkjDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnPmTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSyMlU5OTkQvF2= NWDSRZBnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
LCLC-103H NFO5RphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGxEVENvMUCzTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjh2NkNOwG0> NXrrZ3Q1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOzhxJ{7TRW5ITVJ:L3G+
NCI-H2126 M{TaeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2flNGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDNwMUW2Ne69VQ>? MkHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
PA-1 Ml;CS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml3JTY5pcWKrdHnvckBw\iCqdX3hckBRSS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEOuO|Q2Ps7:TR?= M2DLcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
HSC-4 MknNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmPYTY5pcWKrdHnvckBw\iCqdX3hckBJW0NvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS0MlU2ODcQvF2= M1zjdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
DMS-79 M3\HN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYS2WW9HUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtO|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01PS55MEK4{txO NHPTUm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
EKVX M4HZ[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnTxTY5pcWKrdHnvckBw\iCqdX3hckBGU1[[IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuPVM4P87:TR?= Ml[5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
NOS-1 NYXwdmZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXzJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NE[uNlc3PM7:TR?= M1HtNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
U-118-MG NEPFbWtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUn2[|ZJUW6qaXLpeIlwdiCxZjDoeY1idiCXLUGxPE1OTyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR4LkOzNVTPxE1? MnHMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMN|gwLz6VQV7HSXI9N2F-
Daoy NX7kd|ZkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfCU2tEUW6qaXLpeIlwdiCxZjDoeY1idiCGYX;5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPDZ3Md88US=> M{jp[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
SBC-1 MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXLJcohq[mm2aX;uJI9nKGi3bXHuJHNDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuOVIyQM7:TR?= NF3MTpQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
CAL-51 MmLoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYXMXoJHUW6qaXLpeIlwdiCxZjDoeY1idiCFQVytOVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Py54MECx{txO NF3sPFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw{QC9pPmPBUmdGWjxxYU6=
NY NGK4dnJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVHLb4RvUW6qaXLpeIlwdiCxZjDoeY1idiCQWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS4Mlc3OjkQvF2= M17BfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
BxPC-3 MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2jMNmlvcGmkaYTpc44hd2ZiaIXtZY4hSniSQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFgvQDByMt88US=> M3;KPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
MOLT-16 MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXzJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PU4zOzB2zszN M33Hc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=
NCI-H1155 NHX6WmtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYjtUYlGUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFEyPTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12OT65PFU2|ryP M3vXZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFM5Nyd-U1HOS2VTRC:jPh?=

... Click to View More Cell Line Experimental Data

In vivo Tretinoin-treated old male Fischer 344 rats have 30% lower protein content in the renal cortex than control old rats, this effect may depend on the inhibition of the expression of tumor necrosis factor-beta1, a matrigenic cytokine, and osteopontin, a protein with cell adhesive and chemotactic properties. [1] Tretinoin has the ability to prevent the major steroid-induced biomechanical changes in hairless mouse dermal connective tissue that contribute to atrophy. [3] Tretinoin combined with imiquimod leads to faded tattoos and moderate clearance of pigment on histopathology in the guinea pig. [4] Tretinoin increases fibroplastic proliferation in the Skin incisions were made in 45 CD-1 mice, but the production of collagen was diminished. [5]

Protocol

Solubility (25°C)

In vitro DMSO 60 mg/mL (199.73 mM)
Water Insoluble
Ethanol '''6 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 300.4
Formula

C20H28O2

CAS No. 302-79-4
Storage 3 years -20°C(in the dark) powder
2 years -80°C(in the dark) in solvent
Synonyms Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A
Smiles CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04149418 Not yet recruiting Other: Yogurt|Other: Control food Obesity|Inflammation University of Wisconsin Madison|National Dairy Council|University of Massachusetts Amherst September 2021 Not Applicable
NCT03327064 Recruiting Drug: UAB30|Drug: Placebo Non-melanoma Skin Cancer University of Alabama at Birmingham October 1 2020 Phase 1|Phase 2
NCT04660916 Completed Drug: Isotretinoin Isotretinoin|Nail Abnormality Sinan Özçelik|Balikesir University October 22 2019 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field
Tags: buy Tretinoin (NSC 122758) | Tretinoin (NSC 122758) ic50 | Tretinoin (NSC 122758) price | Tretinoin (NSC 122758) cost | Tretinoin (NSC 122758) solubility dmso | Tretinoin (NSC 122758) purchase | Tretinoin (NSC 122758) manufacturer | Tretinoin (NSC 122758) research buy | Tretinoin (NSC 122758) order | Tretinoin (NSC 122758) mouse | Tretinoin (NSC 122758) chemical structure | Tretinoin (NSC 122758) mw | Tretinoin (NSC 122758) molecular weight | Tretinoin (NSC 122758) datasheet | Tretinoin (NSC 122758) supplier | Tretinoin (NSC 122758) in vitro | Tretinoin (NSC 122758) cell line | Tretinoin (NSC 122758) concentration | Tretinoin (NSC 122758) nmr
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID