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Retinoid Receptor

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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1653 Retinoic acid (Tretinoin, Vitamin A acid) Retinoic acid (Tretinoin, Vitamin A acid) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), and can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Tretinoin (NSC 122758) can be used to induce animal models of osteoporosis.
Nat Commun, 2025, 16(1):616
Biomaterials, 2025, 314:122873
Theranostics, 2025, 15(6):2597-2623
Verified customer review of Retinoic acid (Tretinoin, Vitamin A acid)
S2098 Bexarotene Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.
Cell Mol Immunol, 2025, 10.1038/s41423-025-01268-9
Nucleic Acids Res, 2025, 53(14)gkaf669
J Immunother Cancer, 2024, 12(11)e009805
Verified customer review of Bexarotene
S4627 TTNPB (Arotinoid acid) TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.
Environ Int, 2025, 204:109820
Cancer Lett, 2025, 610:217339
Nan Fang Yi Ke Da Xue Xue Bao, 2025, 45(2):322-330
S4260 Tamibarotene Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.
iScience, 2024, 27(10):110862
Cancer Sci, 2024, 10.1111/cas.16280
Cancers (Basel), 2024, 16(7)1311
S2933 AM580 AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.
Cell, 2025, S0092-8674(25)00807-4
Cell Rep, 2023, 42(6):112566
Cell Res, 2022, 10.1038/s41422-022-00668-0
S1368 Acitretin Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.
Int J Mol Sci, 2022, 23(16)9366
Sci Rep, 2021, 11(1):9601
Antimicrob Agents Chemother, 2017, 61(11). pii: e01368-17
Verified customer review of Acitretin
S1276 Adapalene Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.
Int J Mol Sci, 2022, 23(16)9366
Cancer Discov, 2020, 10(7):1058-1077
PLoS Pathog, 2020, 16;16(3):e1008341
S1569 Tazarotene Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.
Int J Mol Sci, 2022, 23(16)9366
Mol Pharm, 2015, 12(9):3399-407
J Clin Invest, 2013, 123(9):3941-51
E2813 SR 11237 SR 11237, a retinoid X receptor (RXR)-specific agonist, can cause RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
Nat Commun, 2024, 15(1):4108
J Am Heart Assoc, 2023, 12(15):e029415
S2833 UVI 3003 UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR) with IC50 of 0.24 μM against human RXR.
Cell Rep, 2023, 10.1016/j.celrep.2023.113369
Genes (Basel), 2023, 14(4)946