For research use only. Not for use in humans.

Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1))

Synonyms: GBR500

Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD.

Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1))

Quality Control

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  • SDS
  • Datasheet

Specificity

Name Citation Integrin ILK Others
Cilengitide trifluoroacetate 70
A-205804 6
GLPG0187 2
GSK-3008348 HCl 0
Bexotegrast (PLN-74809) 0
Cilengitide (EMD 121974) 36
OSU-T315 1
TR-14035 0
Cyclo(RGDyK) TFA 18
SB273005 27
RGD peptide (Arg-Gly-Asp) 26
ILK-IN-3 0
RGD peptide (GRGDNP) 3 caspase-3
ATN-161 22
Cyclo(-RGDfK) TFA 13
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD.
References

Product Details

CAS No. 1238217-55-4
Molecular Weight 144.56
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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