Otilonium Bromide

Catalog No.S3047

For research use only.

Otilonium bromide is an antimuscarinic.

Otilonium Bromide Chemical Structure

CAS No. 26095-59-0

Purity & Quality Control

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Biological Activity

Description Otilonium bromide is an antimuscarinic.
mAChR [1]
In vitro

Otilonium bromide is a quaternary ammonium compound whose spasmolytic action, selective on the distal gastrointestinal tract, is mainly due to its direct myolytic properties. [1] This drug modifies Ca2+ fluxes from extracellular and intracellular pools in the intestinal smooth muscle and is poorly absorbed, thus it exerts its action locally, without any considerable systemic effect. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 113 mg/mL
(200.5 mM)
Water 113 mg/mL
(200.5 mM)
Ethanol 113 mg/mL
(200.5 mM)

Chemical Information

Molecular Weight 563.57


CAS No. 26095-59-0
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Tech Support

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Handling Instructions

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