Home Apoptosis Antioxidant activator γ-Terpinene For research use only.

γ-Terpinene

Synonyms: γ-TPN

γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,

γ-Terpinene Chemical Structure

γ-Terpinene Chemical Structure

CAS: 99-85-4

Purity & Quality Control

Batch: E065001 Purity: 99.38%
99.38

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Biological Activity

Description γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,
In vitro
In vitro

γ-Terpinene(0 to 45 μM) protects DNA against 2,20-azobis(2-amidinopropane hydrochloride)(AAPH)-induced oxidative damage in erythrocytes.But γ-Terpinene accelerates hemolysis when the concentration exceeds 45 μM.[1]
Cell Research Cell lines Human erythrocytes
Concentrations 0-300 μM
Incubation Time 0-700 min
Method

AAPH and erythrocytes are mixed in PBSa to a final concentration at 20 mM and 3.0% (v/v), respectively, to which various concentrations of γ-Terpinene are added. The above mixture is incubated to initiate hemolysis. Aliquots (1.5 mL) are taken out at appropriate intervals and centrifuged at 1700g to obtain the supernatant. The absorbance of the supernatant is measured and plotted versus the reaction time.
In Vivo
In vivo

γ-Terpinene given either systemically (p.o.; 1.56, 3.125, and 6.25 mg/kg) or centrally (i.t or i.c.v; 10 and 20 μg/site) causes significant inhibition of glutamate-induced nociception in mice.[2]
Animal Research Animal Models Chemical nociception model mice(male; Swiss)
Dosages 1.56 mg/kg, 3.125 mg/kg, 6.25 mg/kg
Administration p.o, i.t, i.c.v

Chemical Information & Solubility

Molecular Weight 136.23 Formula

C10H16
CAS No. 99-85-4 SDF --
Storage (From the date of receipt) 2 years -20°C liquid

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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