(-)-Epigallocatechin Gallate

For research use only.

Catalog No.S2250 Synonyms: EGCG

14 publications

(-)-Epigallocatechin Gallate Chemical Structure

Molecular Weight(MW): 458.37

(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 160 In stock
USD 50 In stock
USD 70 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Selleck's (-)-Epigallocatechin Gallate has been cited by 14 publications

4 Customer Reviews

  • PLoS One 2013 8(8), e69519. (-)-Epigallocatechin Gallate purchased from Selleck.

  • PLoS One 2013 8(8), e69519. (-)-Epigallocatechin Gallate purchased from Selleck.

  • EGCG treatment increases cTnI protein levels in ageing hearts. (A) Western blotting analysis using cTnI and cTnT antibodies. b-Actin was used as protein loading control. (B) A summary of Western blotting results of cTnI. Values are expressed as mean S.D. from four separate experiments. Statistical significance was determined by ANOVA followed by least significant difference (LSD) tests. *P < 0.05 as compared with the 18M + EGCG and 3M groups. EGCG: epigallocatechin-3-gallate

    J Cell Mol Med, 2017, 21(10):2481-2490. (-)-Epigallocatechin Gallate purchased from Selleck.

  • (a) Huh7 cells were incubated with HCVcc of JFH-1 for 2 h before overlaying with 1% agarose dissolved in culture medium or with AR3A anti-E2 neutralizing antibodies, in the presence of 20 μg/ml SZA. EGCG (50 μM) was introduced as a positive control. At 48 h post-infection, infected cells were quantified by IF. Nuclei were stained with DAPI. (b) Numbers of cells per positive colony were determined in 15 foci.

    Sci Rep, 2016, 6:27268.. (-)-Epigallocatechin Gallate purchased from Selleck.

Purity & Quality Control

Choose Selective Telomerase Inhibitors

Biological Activity

Description (-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.
In vitro

(-)-Epigallocatechin gallate functions as a powerful antioxidant, preventing oxidative damage in healthy cells, but also as an antiangiogenic and antitumor agent and as a modulator of tumor cell response to chemotherapy. (-)-Epigallocatechin gallate shows multiple anticancer effects, such as anti-proliferation, anti-angiogenesis, transformation prevention of various cancer cells, cancer cell cycle arrest and inhibition of tumor metastasis. (-)-Epigallocatechin gallate exerts multi-anticancer effects through regulating several cancer-related cell signal pathways (regulated the function or the expression of key signal proteins, such as nuclear factor-κB, MAPKs and activator protein-1, EGFR, IGF, COX-2 signaling pathway, and so on.), effecting methylation of cancer genes and combination of ligand with membrane receptors. [1] (-)-Epigallocatechin gallate also shows an immunomodulating effects. Several types of immune cells in both the innate and adaptive immune systems are known to be affected in varying degrees by (-)-Epigallocatechin gallate. Among them, the dramatic effect on T cell functions has been repeatedly demonstrated, including T cell activation, proliferation, differentiation, and production of cytokines. Studies using animal models of autoimmune diseases have reported disease improvement in animals treated with green tea/EGCG. [2] (-)-Epigallocatechin gallate displays anti-infective properties. Antiviral activities of (-)-Epigallocatechin gallate with different modes of action have been demonstrated on diverse families of viruses, such as Retroviridae, Orthomyxoviridae and Flaviviridae and include important human pathogens like human immunodeficiency virus, influenza A virus and the hepatitis C virus. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
SH-SY5Y cells NIH4RmNHfW6ldHnvckBie3OjeR?= NX;VbG5FVmW3cn;wdo91\WO2aX;uJIFo[Wmwc4SgZoV1[S2jbYnsc4llKHCncITp[IUhOS12Mj3pcoR2[2WmIITvfIlkcXS7IHnuJIh2dWGwIGPIMXN[PVliY3XscJMh[XO|ZYPz[YQh[XNibHHjeIF1\SCmZXj5[JJw\2WwYYPlJJJmdGWjc3WsJGVEPTB;MD6wN|k5PyEQvF2= MUCxPVE{QDh3OR?=
human MDA435/LCC6MDR cells MUPGeY5kfGmxbjDhd5NigQ>? NVT6cJF4OTBizszN MXi1JIRigXN? Mn;3UY9lfWyjdHnvckBw\iCSLXfwJEh2dmuwb4fuJI9zcWerbjmgeJJidnOoZXP0[YQhcW5iaIXtZY4hVUSDNEO1M2xESz[PRGKgZ4VtdHNiYYPz[ZN{\WRiYYOgdoV3\XK|aXLs[UBw\iCyYXPsbZRigGWuIILld4l{fGGwY3WgcYVie3W{ZXSgZZMhUUN3MDDmc5IheGGlbHn0ZZhmdCCjdDCxNEB2VSCjZoTldkA2KGSjeYOgZpkhS2WubGTpeIVzKDl4IFHxeYVwfXNiYYPzZZktKEmFNUC9NE4yOjJ4IN88US=> Mn;1NlU6QDVzOUW=
Sf9 cells MlWySpVv[3Srb36gZZN{[Xl? M3LPcGlvcGmkaYTpc44hd2ZiSHnzOk11[WepZXSgbJVu[W5icnXjc41jcW6jboSgSG5OXDFiZYjwdoV{e2WmIHnuJIlve2WldDDT[lkh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIFTORUBu\XSqeXz0doFve2[ncnHz[UBi[3Srdnn0fUB2e2mwZzC1K{1jcW:2aX75cIF1\WRiNEWtZpAhfW6vZYTofYxifGWmIH;yJIhmdWmvZYTofYxifGWmIH;sbYdwdnWlbHXveIll\SC|dXLzeJJifGW|IHHu[EBcO0ifLVHkc21mfCCkeTDsbZF2cWRic3PpcpRqdGyjdHnvckBkd3WwdHnu[{Bu\XSqb3SsJGlEPTB;MD61JO69VQ>? NXq4VWZpOjV2ME[5OFQ>
human U937 cells NFXOUYVHfW6ldHnvckBie3OjeR?= MV\Jcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iVUmzO{Bk\WyuczygTWM2OD1zIN88US=> Mn\WNlI1OTN6NEW=
human HeLa cells MULGeY5kfGmxbjDhd5NigQ>? MW\Jcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iSHXMZUBk\WyuczD1d4lv\yB3Jz3BRXQhS0OJIGTDS{BCT0NiQVfBJGdVXC1|JzDhd{B{fWK|dILheIUhcW6ldXLheIVlKG[xcjCxOUBucW6|IIDybY9zKHSxIHX4eIVve2mxbjDy[YFkfGmxbjDmc4xtd3enZDDifUBkd22yb4Xu[EB4[XOqb4X0JIJ6KHOyaX6teIVtd22ncnnjJJJmeGWjdDDhcZBtcW[rY3H0bY9vKHC{b4TvZ49tNCCLQ{WwQVEvODhizszN M4rTWFIzPDF|OES1
CHO cells NUXkSVZ[S3m2b4TvfIlkyqCjc4PhfS=> NIDv[Wk1QCCq NWKxe3Y3S3m2b4TvfIlkcXS7IHHnZYlve3RiQ1jPJINmdGy|IHX4dJJme3OrbnegU2FVWDGEMzDoZZBtd3S7cHWgNUBi\nSncjC0PEBpenNiYomg[ox2d3Knc3PlcoNmKGKjc3XkJGNmdGyWaYTldk1IdG9iYYPzZZktKEmFNUC9N{4zKM7:TR?= M2fCfVI{OzJ5OEe3
MDCK cells NEnRb29HfW6ldHnvckBie3OjeR?= MojHOEBl[Xm| NHjac5RCdnSrdnnyZYwh[WO2aY\peJkh[WejaX7zeEBqdm[udXXufoEhSSC4aYL1d{ApSS:|d3nu[U9QUC93MUG0OFUwOjByNzjINW4yMSliT3i3JIlv\mWldHXkJIlvKE2GQ1ugZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iC4aYLhcEBz\XCuaXPheIlwdiCjZoTldkA1KGSjeYOgZpkheXWjboTpeIF1cX[nIGLUMXBEWixiRVS1NF05NjNizszN NX\tV245OjJzMUW1PVE>
human HL60 cells NGXCXJJRem:uaX\ldoF1cW:wIHHzd4F6 MW[zJIRigXN? NEHGPZVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgZYZ1\XJiMzDkZZl{NCCLQ{WwQVkvPCEQvF2= NEfFOowyQDZ7M{CyNC=>
HSC-T6 cells  NX3Nd2t{TnWwY4Tpc44h[XO|YYm= NVe1[2g6PDhiaB?= NGXmU5lCdnSrZnnido91cWNiYXP0bZZqfHliYXfhbY5{fCC{YYSgTHNENVR4IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YheHKxbHnm[ZJifGmxbjDh[pRmeiB2ODDodpMh[nliQoLkWUBqdmOxcoDvdoF1cW:wIHHzd4F6NCCLQ{WwQVkvQSEQvF2= MkTuNlE2ODR6NEi=
mouse 3T3-L1 cells NFflWZlHfW6ldHnvckBie3OjeR?= MULJcohq[mm2aX;uJI9nKEd4UFStcYVlcWG2ZXSgUmFFWEhicILv[JVkfGmxbjDpckBud3W|ZTCzWFMuVDFiY3XscJMtKEmFNUC9NlUh|ryP M4W1dVE5OzF|M{C4
mouse RAW264.7 cells MWXGeY5kfGmxbjDhd5NigQ>? MoLEOUBl[Xm| M4TNbWlvcGmkaYTpc44hd2ZiUlHOT2wucW6mdXPl[EBwe3Snb3PsZZN1d2enbnXzbZMhcW5ibX;1d4UhWkGZMk[0Mlch[2WubIOgZZN{\XO|ZXSgZZMh\GWlcnXhd4UhcW5iVGLBVE1xd3OrdHn2[UBufWy2aT3ueYNt\WG2ZXSgZ4VtdHNiYX\0[ZIhPSCmYYnzMEBKSzVyPUK5Mlgh|ryP NEDFNJQzOTR3NkWyNS=>
HSC-T6 cells NHXTN2dRem:uaX\ldoF1cW:wIHHzd4F6 M2\zN2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgdoF1KEiVQz3UOkBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iY3XscEB3cWGkaXzpeJktKEmFNUC9NlkvQCEQvF2= M2PpNlI2OzJ{NEW1
human A431 cells NYn0XnpTWHKxbHnm[ZJifGmxbjDhd5NigQ>? NEXsfmI1QCCq Mn\tRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNEOxJINmdGy|IH;2[ZJmgHC{ZYPzbY5oKEW{YlKgbY4he2W{dX2t[pJm\SCvZXTpeY0h[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHdUXC1zIHHzd4F6NCCHQ{WwQVM5KM7:TR?= MkjiNlQ1PTZyMES=
human MDA-MB-231 cells M1rkO3Bzd2yrZnXyZZRqd25iYYPzZZk> NHTwdlUzPCCq MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk0zOzFiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfS=> NVPi[4wzOjJ2NUmyNFg>
human HepG2 cells MVTGeY5kfGmxbjDhd5NigQ>? MnnqNlQhcA>? MV7Jcohq[mm2aX;uJI9nKG:uZXnjJIFkcWRvaX7keYNm\CC2cnnncJlk\XKrZHWgc5Zmei2jY3P1cZVt[XSrb36gbY4hcHWvYX6gTIVxTzJiY3XscJMhcW6ldXLheIVlKG[xcjCyOEBpenNicnXsZZRqfmVidH:geY51emWjdHXkJINwdnS{b3y= NU\a[ZhbOjF6MkS2PVA>
human HepG2 cells NVvWVlRoTnWwY4Tpc44h[XO|YYm= MYGyOEBp MkjFRY51cW:6aXThcpQh[WO2aY\peJkhcW5iaIXtZY4hUGWyR{KgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJI9nKG:uZXnjJIFkcWRvaX7keYNm\CCUT2Og[4Vv\XKjdHnvckBqdmO3YnH0[YQh\m:{IEK0JIhzeyCkeTDETGNHNUSDIHLhd4VlKG[udX;ybY1mfHKrYzDhd5NigSC{ZXzheIl3\SC2bzD1cpRz\WG2ZXSgZ49vfHKxbB?= NHHXPVAzOTh{NE[5NC=>
human Caco-2 cells M2DHN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVvCWXRvOjVizszN MoLaOkBl[Xm| MYTHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDDZYNwNTJiY3XscJMh[XRiMkWgeW0h[W[2ZYKgOkBl[Xm| MWGxPFMzPDd4Mx?=
mouse 3T3 cells NF\mNWdHfW6ldHnvckBie3OjeR?= MmrhNU0zOCEQvF2= NYH2S3RCOTJiaB?= NUm1R4hbSW62aX3p[5JifG:{eTDhZ5Rqfmm2eTDh[4FqdnO2IGP3bZN{KGGuYnnuc{Bud3W|ZTCzWFMh[2WubIOgZZN{\XO|ZXSgZZMhcW6lcnXhd4Uhd2ZiY3XscEBvfW2kZYLzJIF1KDFidH:gNlAhfU1iYX\0[ZIhOTJiaILzJIJ6KGK7IIPjdoF1[2hvd3;1coQh[XO|YYm= MViyNVA5ODZ2Mh?=
human MDA-MB-231 cells NHvYUWZRem:uaX\ldoF1cW:wIHHzd4F6 MnjhNlQhcA>? NIXPdIVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigQ>? M4HyR|IzPDV7MkC4
human Jurkat cells NHqzUGtHfW6ldHnvckBie3OjeR?= NGS1U5EyOC13NTFOwG0> MlraNlQhcA>? NVHKfpZ1UW6qaXLpeIlwdiCxZjDUUmZidHCqYT3pcoR2[2WmIF7GMYtieHCjQjDhZ5RqfmG2aX;uJIlvKGi3bXHuJGp2emujdDDj[YxteyCjdDCxNEB1dyB3NTD1UUBi\nSncjCyOEBpenNiYomg[Yxm[3S{b4Doc5JmfGmlIH3vZoltcXS7IIPobYZ1KGG|c3H5 NH;aUXEzOTB6ME[0Ni=>
human K562 cells M2WzVmZ2dmO2aX;uJIF{e2G7 M2fpXVI1KGh? MnLCTY5lfWO2aX;uJI9nKDZ5IHvEZUBt[W2rbnnuJJJm[2WydH;yJIV5eHKnc4Ppc44hcW5iaIXtZY4hUzV4MjDj[YxteyCjZoTldkAzPCCqcoOgZpkh\myxdzDjfZRwdWW2comgZY5idHm|aYO= NFLu[JYzOTR|NE[wNy=>
human HL60 cells NIrQVmJHfW6ldHnvckBie3OjeR?= M2nL[FI1KGh? MUTJcoR2[3Srb36gc4YhPjdia1ThJIxidWmwaX6gdoVk\XC2b4Kg[ZhxemW|c3nvckBqdiCqdX3hckBJVDZyIHPlcIx{KGGodHXyJFI1KGi{czDifUBndG:5IHP5eI9u\XS{eTDhcoFtgXOrcx?= MmjYNlE1OzR4MEO=
human Raji cells NITOU3VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYHQbnpJOTBizszN NGrPblU1QCCq NILIPWtIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIGLhbokh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDD2bYFjcWyrdImgZZQhOTBidV2gZYZ1\XJiNEigbJJ{KGK7IITyfZBidiCkbIXlJIJie2WmIH3pZ5Jwe2OxcHnjJIFv[Wy7c3nzJIlvKHC{ZYPlcoNmKG:oIIP1dIVzd3irZHWg[Il{dXW2YYPl MVWyNVQ{PDZyMx?=
human PC3 cells M{jnTHBzd2yrZnXyZZRqd25iYYPzZZk> M{HZdVExNTFyMDFOwG0> MUO0PEBp MYrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCjdDCxNEB1dyBzMECgeW0h[W[2ZYKgOFghcHK|IHL5JIhmdW:leYTvcYV1emmlIHPlcIwh[2:3boTpcochdWW2aH;k M4DoUlI{QDZ5MU[3
human A431 cells M{DQdmZ2dmO2aX;uJIF{e2G7 M{nkXVExOCEQvF2= MVOxNkBp NGTBNYZT\WS3Y4Tpc44hd2ZiY3z1d5RmemmwZzDv[kBITlBvR2DJJIlvKGyrcHnkJJJi\nS|IH;mJIh2dWGwIFG0N|Eh[2WubIOgZZQhOTByIIXNJIFnfGW{IEGyJIhzeyCkeTDjc45nd2OjbDDtbYNzd3Olb4DpZ{BidmGueYPpdy=> NW\nfpllOjR2NU[wNFQ>
human SKBR3 cells NH\YN5FHfW6ldHnvckBie3OjeR?= MUeyNFDPxE1? NGjCbpU{OCCvaX7z NVv5[VQxTG:5boLl[5Vt[XSrb36gc4YhTXKkQkKgdJJwfGWrbjDlfJBz\XO|aX;uJIlvKGi3bXHuJHNMSlJ|IHPlcIx{KGmwIIPldpVuKG[{ZXWgcYVlcXWvIHH0JFIxOCC3TTDh[pRmeiB|MDDtbY5{KGK7IHntcZVvd2[udX;y[ZNk\W6lZTDzeIFqdmmwZz3iZZNm\CClb37mc4NidCCvaXPyc5Nkd3CrYzDhcoFtgXOrcx?= MoTRNlQ1PTZyMES=
human 293T cells M4X2bmZ2dmO2aX;uJIF{e2G7 NF\vcZg2OCEQvF2= NYq2eVN4OTJiaB?= M3fIO2lvcGmkaYTpc44hd2ZiRGnST|FCKGmwIHj1cYFvKDJ7M2SgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJI9nKEeOSUGgeJJidnOlcnnweIlwdiCjY4Tpeol1gSCjdDC1NEB2VSCjZoTldkAyOiCqcoOgZpkh\HWjbD3seYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZk> M3O0cVIzOTV2Nk[0

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
β-catenin / p-AKT / Cyclin D1; 

PubMed: 28693189     


EGCG inhibits β-catenin, p-Akt and cyclin D1 expression in MDA-MB-231 cells. MDA-MB-231 cells were treated with EGCG for 24 h. (A) β-catenin protein expression was analyzed by western blotting. (B) p-Akt and cyclin D1 protein expression were analyzed by western blotting. β-actin was used as a loading control. Each value represents the mean ± standard error of the mean of three independent experiments. EGCG, epigallocatechin gallate; p-, phosphorylated.

p-MAPK / MAPK ; 

PubMed: 30233784     


Effects of EGCG on IGF-I-induced phosphorylation of (A) p44/p42 MAP kinase in MC3T3-E1 cells. The cells were pretreated with various doses of EGCG for 60 min, and then stimulated by 10 nM IGF-I or vehicle for (A) 5 min. Western blot analysis was performed using antibodies against phospho-p44/p42 MAP kinase, p44/p42 MAP kinase. The histograms show quantitative representation of the levels of IGF-I-induced phosphorylation determined from laser densitometric analysis of three independent experiments. EGCG, (−)-epigallocatechin gallate; IGF-I, insulin-like growth factor-I; MAP, mitogen-activated protein.

Notch1 / Notch2 ; 

PubMed: 28443100     


Human primary macrophages derived from peripheral blood mononuclear cells (PBMCs) cultured with autologous serum were pretreated with EGCG (50 μg/mL) for 30 min and exposed to LPS (200 EU/mL) for 3 h. Cell lysates from time course experiments of EGCG treatment were analyzed by western blotting and probed with a Notch1/2 antibody  

28693189 30233784 28443100
Growth inhibiton assay
Cell proliferation ; 

PubMed: 23525843     


The percent EGCG that inhibits the proliferation of colorectal cancer cells at different concentrations. Notes: The x-axis and y-axis are the time after treatment and percentage of EGCG that inhibits the proliferation of colorectal cancer cells at different concentrations. Eight experiments were performed for each treatment, and the inhibition rate of cell proliferation was tested for, using a single factor analysis of variance. Abbreviation: EGCG, epigallocatechin gallate; h, hour.

Cell viability; 

PubMed: 28693189     


Effect of EGCG on the viability of MDA-MB-231 cells. MDA-MB-231 cells were treated with various concentrations of EGCG for 24 h. MTT assay was used to detect the viability of the cells. The optical density value of the untreated cells was regarded as 100%. Each value represents the mean ± standard error of the mean of three independent experiments. EGCG, epigallocatechin gallate.

23525843 28693189

Protocol

Solubility (25°C)

In vitro Ethanol 83 mg/mL warmed (181.07 mM)
DMSO 72 mg/mL warmed (157.07 mM)
Water 23 mg/mL warmed (50.17 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 458.37
Formula

C22H18O11

CAS No. 989-51-5
Storage powder
in solvent
Synonyms EGCG
Smiles C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03928847 Recruiting Drug: Epigallocatechin-3-gallate (EGCG) Idiopathic Pulmonary Fibrosis University of California San Francisco|National Heart Lung and Blood Institute (NHLBI) July 1 2018 Early Phase 1
NCT02779361 Completed Dietary Supplement: Green tea Healthy Volunteers|Doping in Sports Parc de Salut Mar|World Anti-doping Agency January 2016 Phase 1
NCT02577393 Enrolling by invitation Drug: EGCG|Drug: mLDG Lung Neoplasms|Esophagitis|Prevention & Control|Epigallocatechin Gallate Shandong Cancer Hospital and Institute April 2015 Phase 2
NCT02580279 Enrolling by invitation Drug: EGCG|Drug: placebo Breast Neoplasms|Dermatitis|Prevention & Control|Epigallocatechin Gallate Shandong Cancer Hospital and Institute December 2014 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Telomerase Signaling Pathway Map

Related Telomerase Products

Tags: buy (-)-Epigallocatechin Gallate | (-)-Epigallocatechin Gallate supplier | purchase (-)-Epigallocatechin Gallate | (-)-Epigallocatechin Gallate cost | (-)-Epigallocatechin Gallate manufacturer | order (-)-Epigallocatechin Gallate | (-)-Epigallocatechin Gallate distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID