For research use only. Not for use in humans.

Anti-ANO1 / TMEM16A

Cat.No.A2726 Purity:99%

Anti-ANO1 / TMEM16A is a humanized monoclonal antibody that binds to human TMEM16A and modulates its activity, with potential anti-tumor activity. MW: 146.8 KD.

Anti-ANO1 / TMEM16A

Quality Control

Batch: A272601 Purity: 99% Protein concentration: 14.053mg/ml Endotoxin Level: ＜1EU/mg

99

Specificity

Name	Citation	Chloride Channel	Others
T16Ainh-A01	0	+++
NS1652	0	++++	VRAC
CaCCinh-A01	0	++	CaCC
(±)-Shikonin	40	+	chemokine receptor,NF-κB,Proteasome
Adjudin	1	✔	ERK,NF-κB
Dehydroandrographolide	0	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-ANO1 / TMEM16A is a humanized monoclonal antibody that binds to human TMEM16A and modulates its activity, with potential anti-tumor activity. MW: 146.8 KD.
References	[1] https://patents.google.com/patent/US20130323252A1/en

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	146.8
Isotype	Human IgG1-Kappa
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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