Dasatinib Monohydrate

For research use only.

Catalog No.S7782 Synonyms: BMS-354825 Monohydrate

205 publications

Dasatinib Monohydrate Chemical Structure

CAS No. 863127-77-9

Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.

Selleck's Dasatinib Monohydrate has been cited by 205 publications

Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
Targets
Abl [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
c-Kit (D816V) [2]
(Cell-free assay)
c-Kit (wt) [2]
(Cell-free assay)
0.6 nM 0.8 nM 37 nM 79 nM
In vitro

Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I. Dasatinib has a two-log (∼325-fold) increased potency relative to imatinib. Dasatinib potently inhibits wild-type Abl kinase and all mutants except T315I over a narrow range. Dasatinib directly targets wild-type and mutant Abl kinase domains and inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner. Dasatinib displays 325-fold greater potency compared with imatinib against cells expressing wild-type Bcr-Abl. [1] The percent of colonies of TgE bone marrow cells are decreased from 100% in untreated wells to 4.12% in Dasatinib treated wells. In the presence of Dasatinib, the difference in the percentage of colonies formed by WT and TgE bone marrow cells is statistically significant. Expression of LMP2A is able to promote B lymphocyte survival and proliferation, which can be inhibited by targeting Lyn and/or c-Abl kinases through Dasatinib. [3] Dasatinib treatment inhibits Src signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer cells. Treatment with increasing doses of Dasatinib (0.019 μM to 1.25 μM) for 3 days inhibits the growth of the C643, TPC1, BCPAP, and SW1736 cell lines by about 50% at low nanomolar concentrations, while higher concentrations are required to inhibit the growth of the K1 cell line. Treatment with 10 nM or 50 nM Dasatinib results in a 9-22% increase of cells in the G1 population among BCPAP and SW1736 and K1 cells, and a corresponding 7-18% decrease in the percentage of cells in the S phase. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K562 cell MmTLVJJwdGmoZYLheIlwdiCjc4PhfS=> NGjqcmQ4OiCq NWj1NoF1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjByMTFOwG0> NYP2[GJuOTV4MUW1NVI>
WiDr cell MWfQdo9tcW[ncnH0bY9vKGG|c3H5 NYXCd|k1PzJiaB?= NWr4clE2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDXbWRzKGOnbHzzJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjB3MjFOwG0> MXOxOVYyPTVzMh?=
PC3 cell NEH2d|NRem:uaX\ldoF1cW:wIHHzd4F6 MVy3NkBp NIHOXHRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDh[pRmeiB5MjDodpMtKEmFNUC9NE4xODl2IN88US=> NGf0OZUyPTZzNUWxNi=>
MDA-MB-231 cell NF3WW5RRem:uaX\ldoF1cW:wIHHzd4F6 NIDOfJc4OiCq MYTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk0zOzFiY3XscJMh[W[2ZYKgO|IhcHK|LDDJR|UxRTBwMEGyJO69VQ>? M3PNNVE2PjF3NUGy
M07ep210 cell NEX0bo1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1Ln[VQ5KGh? Ml2zS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUVA4\XB{MUCgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KFt|SG30bJlucWSrbnWgeZB1[WunIHHzd4F6NCCLQ{WwQVAvODdibl2= NYriOGVwOTd7NU[wPFA>
K562 cell M1frdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXe0PEBp NX;ab21FT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUzV4MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhYzOKXYTofY1q\GmwZTD1dJRic2ViYYPzZZktKEmFNUC9NE4xODFizszN M1K1SVE4QTV4MEiw
M07e cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPjOFghcA>? M4rxUGdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG0xP2ViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHs{UF22aIntbYRqdmVidYD0ZYtmKGG|c3H5MEBKSzVyPUCuNFAyOiEQvF2= NVjhOWdtOTd7NU[wPFA>
K562 cell NF3afWREgXSxdH;4bYNqfHliYYPzZZk> M2foelczKGh? MofuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC3NkBpenNiYomgW3NVNThicnXh[4VvfCCkYYPl[EBOXFRiYYPzZZktKEmFNUC9NVIvQDNizszN NGPZVVUzOjJzN{i3Oy=>
U937 cell NHHlXHVEgXSxdH;4bYNqfHliYYPzZZk> MXW3NkBp M1viPWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHU6OzdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHdUXC16IILlZYdmdnRiYnHz[YQhVVSWIHHzd4F6NCCLQ{WwQVE{NjZ|IN88US=> NFXW[IgzOjJzN{i3Oy=>
K562 cell MVzQdo9tcW[ncnH0bY9vKGG|c3H5 MVS3NkBp NUj2e3hjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyPUCuO{BvVQ>? NIPHZ5QzOzV{MUCyNC=>
MDA-MB-435S cell M3PWUXBzd2yrZnXyZZRqd25iYYPzZZk> NYnO[XN1PzJiaB?= MonKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPRFGtUWIuPDN3UzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVMvQSEQvF2= Mn7uNlM2OjFyMkC=
NCI-H460 cell MnXFVJJwdGmoZYLheIlwdiCjc4PhfS=> NFjEOWQ4OiCq M33BPWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME24Mlk6KM7:TR?= M3XZclI{PTJzMEKw
NCI-H23 cell NEnOSG9Rem:uaX\ldoF1cW:wIHHzd4F6 MXi3NkBp MYnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE6FST3INlMh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD1{LkK3JO69VQ>? MljLNlM2OjFyMkC=
A549 cell NWTzNVJWWHKxbHnm[ZJifGmxbjDhd5NigQ>? M4\aflczKGh? NI\RVGNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD1zMj62OkDPxE1? NXzsPYx2OjN3MkGwNlA>
T47D cell MlO0VJJwdGmoZYLheIlwdiCjc4PhfS=> NGTtZ4U4OiCq M1XiemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVES3SEBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxRTBwOTFOwG0> NYTCOWdZOjN3MkGwNlA>
HCT116 cell Mmq1VJJwdGmoZYLheIlwdiCjc4PhfS=> NUiwPY9iPzJiaB?= Ml\zRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD1{LkOg{txO NVPJ[2d1OjN3MkGwNlA>
MCF7 cells MXHQdo9tcW[ncnH0bY9vKGG|c3H5 MXu3NkBp MkK0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVA:Oi53NzFOwG0> NYSzVoduOjN3MkGwNlA>
RXF 393NL cell NULQ[XJjS3m2b4TvfIlkcXS7IHHzd4F6 NHjrS3c1KGSjeYO= NXLsTZpxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWliIIEO5N25NKGOnbHzzJIFnfGW{IESg[IF6eyCkeTDwdo9xcWSrdX2gbY9lcWSnIIP0ZYlvcW6pLDDJR|UxRTJzLkegcm0> MYSyN|I2OzB5NB?=
PRXF DU145 cell MUDDfZRwfG:6aXPpeJkh[XO|YYm= NF7NbZg1KGSjeYO= NUXCeoZIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWFK[RjDEWVE1PSClZXzsd{Bi\nSncjC0JIRigXNiYomgdJJweGmmaYXtJIlw\GmmZTDzeIFqdmmwZzygTWM2OD1yLkC2NlMh|ryP MlTtNlMzPTNyN{S=
LXFA 983L cell MU\DfZRwfG:6aXPpeJkh[XO|YYm= NFWwc5M1KGSjeYO= NVf0NW1xS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVFiIQTC5PFNNKGOnbHzzJIFnfGW{IESg[IF6eyCkeTDwdo9xcWSrdX2gbY9lcWSnIIP0ZYlvcW6pLDDJR|UxRTV4LkWgcm0> M3XB[VI{OjV|MEe0
GXF251L cell MULDfZRwfG:6aXPpeJkh[XO|YYm= MUW0JIRigXN? NXj5cXAyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hT1iIMkWxUEBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF0zNjJ3IN88US=> MW[yN|I2OzB5NB?=
CXF 1103L cell MXHDfZRwfG:6aXPpeJkh[XO|YYm= MV:0JIRigXN? M2frfGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNZTiBzMUCzUEBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF01NjN4IN88US=> NXnaR2MzOjN{NUOwO|Q>
PAXF 1657L cell MYTDfZRwfG:6aXPpeJkh[XO|YYm= NVLT[Jk2PCCmYYnz MVrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQRXhHKDF4NUfMJINmdGy|IHHmeIVzKDRiZHH5d{BjgSCycn;wbYRqfW1iaX;kbYRmKHO2YXnubY5oNCCLQ{WwQVAvOTJzIN88US=> NV7y[ZZiOjN{NUOwO|Q>
NCI-H1648 cell M4Tkc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFTSXVZKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY1QCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEKwNVEh|ryP M1rLd3NCVkeHUh?=
NCI-H1838 cell M1naPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUizPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzB5M{Og{txO MYXTRW5ITVJ?
NCI-H2126 cell NILNZo9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEfKcGxKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlEzPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwOEe1OVIh|ryP M33DZnNCVkeHUh?=
NCI-H2141 cell NYXkTWFXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7zbVhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE1OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lke3OVQh|ryP MmjkV2FPT0WU
NCI-H2107 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\VO3hRUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyODdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mz60PFQ4KM7:TR?= MWTTRW5ITVJ?
NCI-H747 cell MlfBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDN4MjFOwG0> Mkf3V2FPT0WU
NCI-H720 cell M3[x[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{LDNWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NlAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOC5{N{OzJO69VQ>? MnG2V2FPT0WU
NKM-1 cell M2TrWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH;WV2xKdmirYnn0bY9vKG:oIHj1cYFvKE6NTT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlMxQDV7IN88US=> MkH1V2FPT0WU
NMC-G1 cell M4S5cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVfJcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVYxPiEQvF2= NX3VVZROW0GQR1XS
NTERA-S-cl-D1 cell NEHNWmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVnJcohq[mm2aX;uJI9nKGi3bXHuJG5VTVKDLWOtZ4wuTDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUKyPFMh|ryP M4DJ[3NCVkeHUh?=
OCI-AML2 cell MlToS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV\Jcohq[mm2aX;uJI9nKGi3bXHuJG9EUS2DTVyyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME21Mlg3OTV2IN88US=> NFjuNXRUSU6JRWK=
OCUB-M cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEXVclBKdmirYnn0bY9vKG:oIHj1cYFvKE:FVVKtUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4xPDRzMjFOwG0> Mn\1V2FPT0WU
OPM-2 cell MmDSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWjIN4NUUW6qaXLpeIlwdiCxZjDoeY1idiCRUF2tNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OE4zPzZ6NTFOwG0> MmDoV2FPT0WU
OS-RC-2 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3HWbmlvcGmkaYTpc44hd2ZiaIXtZY4hV1NvUlOtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjB|IN88US=> M3zvTHNCVkeHUh?=
ONS-76 cell M{jxUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF7yVWJKdmirYnn0bY9vKG:oIHj1cYFvKE:QUz23OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE41Ojl3MTFOwG0> M1m2U3NCVkeHUh?=
OVCAR-4 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUPGZoE4UW6qaXLpeIlwdiCxZjDoeY1idiCRVlPBVk01KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjN5NEOzJO69VQ>? MlzEV2FPT0WU
NCI-H446 cell M{\qV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NG[1UllKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOFQ3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjZ{N{[g{txO M2\ocHNCVkeHUh?=
NCI-H510A cell NXHrTldjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NW\qWld7UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFUyOEFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTF7LkO5O|Mh|ryP MX7TRW5ITVJ?
PF-382 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rJRWlvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE4Pjd6IN88US=> M13pd3NCVkeHUh?=
NCI-H64 cell NYi0d5ZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlHJTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSE[0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yPU43OjV|IN88US=> NWXlNHlUW0GQR1XS
PSN1 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX35TFdxUW6qaXLpeIlwdiCxZjDoeY1idiCSU16xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1PDd2IN88US=> NHnKZ5RUSU6JRWK=
QIMR-WIL cell M{O0ZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2rUUGlvcGmkaYTpc44hd2ZiaIXtZY4hWUmPUj3XTWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPzB4Mkmg{txO Mnn0V2FPT0WU
RL95-2 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWHZSJN4UW6qaXLpeIlwdiCxZjDoeY1idiCUTEm1MVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTB|ODFOwG0> M3fJeXNCVkeHUh?=
RCC10RGB cell Mo\qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVz2RVZrUW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC52OUGxJO69VQ>? MkPSV2FPT0WU
RKO cell NUnvNVVnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH[2coJKdmirYnn0bY9vKG:oIHj1cYFvKFKNTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD61Nlk3PiEQvF2= NV72W5NSW0GQR1XS
NCI-SNU-16 cell MofIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnXFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvU17VMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF05NjV4MUK4JO69VQ>? NWr2NIFmW0GQR1XS
RPMI-6666 cell Mo\xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3q0cWlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF04NjJ5ME[3JO69VQ>? MoHjV2FPT0WU
NEC8 cell NX:xWpllT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXHnTHN1UW6qaXLpeIlwdiCxZjDoeY1idiCQRVO4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20OE4{OzZizszN M3exSnNCVkeHUh?=
RS4-11 cell MmPDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnrhTY5pcWKrdHnvckBw\iCqdX3hckBTWzRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUeuOlU4QDdizszN NGr1OJpUSU6JRWK=
RXF393 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWrSb5MyUW6qaXLpeIlwdiCxZjDoeY1idiCUWF[zPVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODJ|NUeg{txO NYe3UVZPW0GQR1XS
Raji cell MkDZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmLDTY5pcWKrdHnvckBw\iCqdX3hckBT[WqrIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMz63OFk4KM7:TR?= NEDNOI1USU6JRWK=
NOS-1 cell NULRcVIyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4\vSGlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFA3OTJ7IN88US=> NU\KcY5iW0GQR1XS
SBC-1 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF3OfJlKdmirYnn0bY9vKG:oIHj1cYFvKFOEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlU4QTh2IN88US=> MojkV2FPT0WU
SF126 cell M{TKOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M37nV2lvcGmkaYTpc44hd2ZiaIXtZY4hW0ZzMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|U1OSEQvF2= M{\U[nNCVkeHUh?=
SF539 cell NXf1WYhUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFvWXoZKdmirYnn0bY9vKG:oIHj1cYFvKFOINUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xN{45PTV5IN88US=> NXLhZXp4W0GQR1XS
SH-4 cell M37PZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUi0NVMh|ryP MmO4V2FPT0WU
OMC-1 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI[0epZKdmirYnn0bY9vKG:oIHj1cYFvKE:PQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yO{4yPDJ{IN88US=> MoXLV2FPT0WU
SIG-M5 cell MlfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33t[2lvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME25MlAzPDl|IN88US=> MlLkV2FPT0WU
SJSA-1 cell NI\Id3ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVTJcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;OD63NlgxPSEQvF2= NUHuboVsW0GQR1XS
SK-LMS-1 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWLJcohq[mm2aX;uJI9nKGi3bXHuJHNMNUyPUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zMlEyQDh4IN88US=> MVjTRW5ITVJ?
SK-NEP-1 cell NW\P[XlmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4G2XmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTlXQMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvQDlzNUWg{txO M133dnNCVkeHUh?=
SKM-1 cell NXvBd|ZCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkLrTY5pcWKrdHnvckBw\iCqdX3hckBUU01vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;OT6wNVc{PCEQvF2= NGjUeFdUSU6JRWK=
SK-PN-DW cell Ml[4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmXRTY5pcWKrdHnvckBw\iCqdX3hckBUUy2STj3EW{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|YvOTl2MzFOwG0> MkXFV2FPT0WU
SK-UT-1 cell Mn[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnlXXJKdmirYnn0bY9vKG:oIHj1cYFvKFONLWXUMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVIvOTZ4OUOg{txO NYO4UnR7W0GQR1XS
SNB75 cell NHezcXVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NU\nPHpVUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDR|NTFOwG0> M17wWHNCVkeHUh?=
REH cell NHftSotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYf0RnhEUW6qaXLpeIlwdiCxZjDoeY1idiCURVigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUKwMlY{PTdizszN NH34eGRUSU6JRWK=
SNU-C2B cell MljaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWrYOldNUW6qaXLpeIlwdiCxZjDoeY1idiCVTmWtR|JDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yNjNyNUi5JO69VQ>? NH\qR2lUSU6JRWK=
RPMI-8866 cell M{LsXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvOEi2OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVcvPDR3NTFOwG0> MVrTRW5ITVJ?
SW872 cell NUfsb3BIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkK3TY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wOFE3OSEQvF2= NFvaTYhUSU6JRWK=
SW962 cell M3zu[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{fDUWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVEzQTJizszN MlLrV2FPT0WU
SF268 cell NXnhdY1NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHizeJlKdmirYnn0bY9vKG:oIHj1cYFvKFOIMk[4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE4PDB2IN88US=> NGPUOWRUSU6JRWK=
TE-1 cell NUXYbnU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn3YTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkGwOVQh|ryP NVPn[Y9iW0GQR1XS
8-MG-BA cell NX65eJRvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGj1W5NKdmirYnn0bY9vKG:oIHj1cYFvKDhvTVetRmEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTV2NUig{txO NXv2bJd[W0GQR1XS
A101D cell NHjYNHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUDrS5VxUW6qaXLpeIlwdiCxZjDoeY1idiCDMUCxSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4xOzB2MzFOwG0> NEe3bJpUSU6JRWK=
A253 cell NEHkbHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVf4OGFHUW6qaXLpeIlwdiCxZjDoeY1idiCDMkWzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zMlc{OjR4IN88US=> MX3TRW5ITVJ?
A3-KAW cell NFzUTotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUDJcohq[mm2aX;uJI9nKGi3bXHuJGE{NUuDVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD65PFQ2OiEQvF2= Mkm0V2FPT0WU
A4-Fuk cell MmfpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGrEdmRKdmirYnn0bY9vKG:oIHj1cYFvKEF2LV\1b{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|gvOTByOTFOwG0> NXrEPHM6W0GQR1XS
A388 cell MoW0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{S2SmlvcGmkaYTpc44hd2ZiaIXtZY4hSTN6ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wOVA6PSEQvF2= M{e3bXNCVkeHUh?=
ACN cell MkTHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlG2TY5pcWKrdHnvckBw\iCqdX3hckBCS05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwOEKyOVIh|ryP NGO3PW5USU6JRWK=
A704 cell M2X5bWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn;HTY5pcWKrdHnvckBw\iCqdX3hckBCPzB2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCxOFkyKM7:TR?= NF3QbmZUSU6JRWK=
ALL-PO cell MnT1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4[0R2lvcGmkaYTpc44hd2ZiaIXtZY4hSUyOLWDPJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNE44QTN6IN88US=> M4DwPHNCVkeHUh?=
ARH-77 cell NFjrSJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn7iTY5pcWKrdHnvckBw\iCqdX3hckBCWkhvN{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOuOFY6OTVizszN MX;TRW5ITVJ?
SR cell NXPOeXV7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVzJcohq[mm2aX;uJI9nKGi3bXHuJHNTKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01NjR7OUW0JO69VQ>? NWHtU4EzW0GQR1XS
BB65-RCC cell NYX0OIgzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnfDTY5pcWKrdHnvckBw\iCqdX3hckBDSjZ3LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xQDJ{NzFOwG0> M3f3S3NCVkeHUh?=
BB49-HNC cell NUPu[2JXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfGT5lnUW6qaXLpeIlwdiCxZjDoeY1idiCEQkS5MWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5|OEW5PUDPxE1? M2jkcHNCVkeHUh?=
BC-1 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDoPHNZUW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yPE43PTFizszN NELudmZUSU6JRWK=
BC-3 cell M4\Ne2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWHJcohq[mm2aX;uJI9nKGi3bXHuJGJENTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTF{LkGxN|gh|ryP Ml3vV2FPT0WU
BL-41 cell NUPDR4drT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn\KTY5pcWKrdHnvckBw\iCqdX3hckBDVC12MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6yPVEzOyEQvF2= MXTTRW5ITVJ?
BL-70 cell MlfES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MknUTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFAxODB6MkG4JO69VQ>? M4PsWHNCVkeHUh?=
SW684 cell NIWwcnZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4n3TmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4OESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|Q6QCEQvF2= NWPJZnlYW0GQR1XS
BOKU cell NHLDT3hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlfMTY5pcWKrdHnvckBw\iCqdX3hckBDV0uXIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkS5NVM{KM7:TR?= M2PLUXNCVkeHUh?=
SW954 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVfJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTV2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCyPVI4KM7:TR?= MkW1V2FPT0WU
C2BBe1 cell MoS5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnHc3dKdmirYnn0bY9vKG:oIHj1cYFvKEN{QlLlNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xQDNyODFOwG0> M4P4WHNCVkeHUh?=
BV-173 cell MnezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3HqSmlvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxODByMEGwPUDPxE1? MYXTRW5ITVJ?
Becker cell MmrUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mmi2TY5pcWKrdHnvckBw\iCqdX3hckBD\WOtZYKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFMxODNizszN NV[0ZYF3W0GQR1XS
SW982 cell NX7SPVY6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn;ITY5pcWKrdHnvckBw\iCqdX3hckBUXzl6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVEyPSEQvF2= NUfoR5NxW0GQR1XS
697 cell MlHWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH\MXY5KdmirYnn0bY9vKG:oIHj1cYFvKDZ7NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xPVk5PyEQvF2= NHnQeJhUSU6JRWK=
TE-15 cell M3j0OGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYjJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwOVg6OSEQvF2= NXzMUWYxW0GQR1XS
TE-11 cell NWXNZ5hlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoT1TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wO|g2QCEQvF2= MofEV2FPT0WU
TE-5 cell MnezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVnubmdMUW6qaXLpeIlwdiCxZjDoeY1idiCWRT21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlc6OTN7IN88US=> NWGzb2x5W0GQR1XS
TE-6 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUG0U3B5UW6qaXLpeIlwdiCxZjDoeY1idiCWRT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlIyOjJ4IN88US=> NIDwUZFUSU6JRWK=
TE-9 cell M4D1Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2Tud2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD64O|U{OiEQvF2= M3rwOHNCVkeHUh?=
TGBC24TKB cell NVnFfGFUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIXTOIZKdmirYnn0bY9vKG:oIHj1cYFvKFSJQlOyOHRMSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yNEe2NUDPxE1? NEHsbHVUSU6JRWK=
TGW cell MkfVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH;V[oZKdmirYnn0bY9vKG:oIHj1cYFvKFSJVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MUGuNlgzQCEQvF2= MoHnV2FPT0WU
TK10 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2HoTGlvcGmkaYTpc44hd2ZiaIXtZY4hXEtzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVE4PCEQvF2= NVO2Z5JjW0GQR1XS
TGBC1TKB cell M2\1Umdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkfSTY5pcWKrdHnvckBw\iCqdX3hckBVT0KFMWTLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPjF4NDFOwG0> NYXyellsW0GQR1XS
A498 cell M3rUUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX73TZNzUW6qaXLpeIlwdiCxZjDoeY1idiCDNEm4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA4Ojh2IN88US=> MWTTRW5ITVJ?
UACC-257 cell NXLBdHpqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mm[2TY5pcWKrdHnvckBw\iCqdX3hckBWSUOFLUK1O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVIvQTF7ODFOwG0> M1fkb3NCVkeHUh?=
U-87-MG cell M4Xr[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHvYcY9KdmirYnn0bY9vKG:oIHj1cYFvKFVvOEetUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVMxNjd4NjFOwG0> M3:wOnNCVkeHUh?=
BB30-HNC cell NX3GWXJ7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1m1UWlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODV2M{eg{txO Ml3ZV2FPT0WU
no-10 cell NILiNYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlzGTY5pcWKrdHnvckBw\iCqdX3hckBvdy1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6zNVk{OSEQvF2= MXnTRW5ITVJ?
CAS-1 cell NVf5O|ZwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUnFOG5HUW6qaXLpeIlwdiCxZjDoeY1idiCFQWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU41ODl7MjFOwG0> MYTTRW5ITVJ?
CGTH-W-1 cell M3O0emdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2rGXWlvcGmkaYTpc44hd2ZiaIXtZY4hS0eWSD3XMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODN3NEig{txO NXLTeGVZW0GQR1XS
TE-10 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFnqZ4hKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA3OzV5IN88US=> NVzkUmZiW0GQR1XS
COLO-684 cell NYqwS|NiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWHTdZEzUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVY5PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:PDZwMkK1PEDPxE1? M3rQbnNCVkeHUh?=
TE-12 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rUcWlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFE5PjFizszN MY\TRW5ITVJ?
COR-L279 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MknHTY5pcWKrdHnvckBw\iCqdX3hckBEV1JvTEK3PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OFAvOjh3MjFOwG0> NUHi[2o1W0GQR1XS
TE-8 cell MnizS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1i0RmlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVU4PiEQvF2= NGnLTGxUSU6JRWK=
CP66-MEL cell NYTpXGxoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFrWVnBKdmirYnn0bY9vKG:oIHj1cYFvKEOSNk[tUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjF7NUOxJO69VQ>? MX;TRW5ITVJ?
CTV-1 cell NF\Vc2FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M33oXGlvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFAxODRyM{[g{txO NYPGOldVW0GQR1XS
VA-ES-BJ cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M37iTWlvcGmkaYTpc44hd2ZiaIXtZY4hXkFvRWOtRmoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODN7MEKg{txO M3zVcHNCVkeHUh?=
D-263MG cell NHf2fYtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHvnOJlKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOzZ{MkSg{txO MWnTRW5ITVJ?
D-336MG cell NFSwUVJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzN4TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFA3Ojl6IN88US=> Mn\LV2FPT0WU
D-502MG cell NWTld2NJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFjjVmFKdmirYnn0bY9vKG:oIHj1cYFvKERvNUCyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVEvOjN|N{[g{txO NYi0XWlqW0GQR1XS
DJM-1 cell NVO1R29qT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1vhWmlvcGmkaYTpc44hd2ZiaIXtZY4hTEqPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPU[uOFg2PThizszN NX:3Wm5UW0GQR1XS
no-11 cell NXjvRmNNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkWwNlI5KM7:TR?= M17udXNCVkeHUh?=
DMS-153 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2XuUGlvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUG1N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVQvODB{ODFOwG0> NGTkVWFUSU6JRWK=
DSH1 cell NV32fGo5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NE\ObYFKdmirYnn0bY9vKG:oIHj1cYFvKESVSEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNlQxODFizszN M4\0[nNCVkeHUh?=
DU-4475 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXTJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUiuNlE3PTJizszN MXzTRW5ITVJ?
EB-3 cell NWj0c5NiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGVDNTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTN2LkOxNVgh|ryP MYnTRW5ITVJ?
EHEB cell MmfJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF3Ud2NKdmirYnn0bY9vKG:oIHj1cYFvKEWKRVKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGwMlA3PTZizszN M4nKVXNCVkeHUh?=
COLO-829 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYjMPGlYUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVgzQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zMkKxN{DPxE1? M4rQbHNCVkeHUh?=
CP67-MEL cell NGjHfW9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVflS2NJUW6qaXLpeIlwdiCxZjDoeY1idiCFUE[3MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5{MES4PEDPxE1? M2XB[HNCVkeHUh?=
ES8 cell M{LLN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWHMeJM2UW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOyMlEzPTJizszN Mmj2V2FPT0WU
EVSA-T cell Mni4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVPJcohq[mm2aX;uJI9nKGi3bXHuJGVXW0FvVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;OT6yO|c6OyEQvF2= MmrMV2FPT0WU
ES4 cell M3nXTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJGVUPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OS5yNUG0OUDPxE1? M3rPXnNCVkeHUh?=
ETK-1 cell M1O1VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVfvTpEyUW6qaXLpeIlwdiCxZjDoeY1idiCHVFutNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjh|MjFOwG0> M1XENXNCVkeHUh?=
ES6 cell NFTPTG5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGVUPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yM{G5N{DPxE1? M2LzVHNCVkeHUh?=
EW-24 cell M1:xVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{DtN2lvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMkSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuO|gyPjVizszN NFvYfJdUSU6JRWK=
EoL-1-cell cell NX;JN5c3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{nqWWlvcGmkaYTpc44hd2ZiaIXtZY4hTW:OLUGtZ4VtdCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yMECwNVMxQSEQvF2= MmHVV2FPT0WU
Calu-6 cell NUTa[Yx[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFj2[GdKdmirYnn0bY9vKG:oIHj1cYFvKEOjbIWtOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N{4xPTd2MTFOwG0> M3S4TXNCVkeHUh?=
GAK cell NF3kUZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVXJcohq[mm2aX;uJI9nKGi3bXHuJGdCUyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OzFwMk[4OkDPxE1? MYjTRW5ITVJ?
D-247MG cell NWnUNHViT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoCwTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ2N13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME22MlEzPTF7IN88US=> MV\TRW5ITVJ?
GB-1 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXXJcohq[mm2aX;uJI9nKGi3bXHuJGdDNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEKxOVch|ryP MYjTRW5ITVJ?
GI-ME-N cell NGW2cZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkThTY5pcWKrdHnvckBw\iCqdX3hckBIUS2PRT3OJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA3OTF6IN88US=> M2LOenNCVkeHUh?=
GCIY cell NYW2RmQyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3HqXmlvcGmkaYTpc44hd2ZiaIXtZY4hT0OLWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wPVY2PiEQvF2= MlHRV2FPT0WU
GT3TKB cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTPOWJUUW6qaXLpeIlwdiCxZjDoeY1idiCJVEPUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVkvOzV3NE[g{txO MWHTRW5ITVJ?
HC-1 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWTzcIN1UW6qaXLpeIlwdiCxZjDoeY1idiCKQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yOE42PTVzIN88US=> MnzzV2FPT0WU
HAL-01 cell NHriPWVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3z1S2lvcGmkaYTpc44hd2ZiaIXtZY4hUEGOLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xPU44PTR|IN88US=> M12xVHNCVkeHUh?=
HCC1187 cell MnT5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVjRNnBzUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OxNVg4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{PS56MEWyJO69VQ>? MkHKV2FPT0WU
DEL cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4XGTGlvcGmkaYTpc44hd2ZiaIXtZY4hTEWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12MT65NFg3KM7:TR?= NWTRfIxsW0GQR1XS
HCC1599 cell Mn3wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGDObWdKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVMzNjN|MkWg{txO MofaV2FPT0WU
DOHH-2 cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml61TY5pcWKrdHnvckBw\iCqdX3hckBFV0iKLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFE4OTlizszN MXvTRW5ITVJ?
HCC2157 cell NU\KV3VQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVPibWM4UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OyNVU4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{Py57OUS2JO69VQ>? MlfVV2FPT0WU
HCE-4 cell NGDndYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2D1UGlvcGmkaYTpc44hd2ZiaIXtZY4hUEOHLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNlY1OzlizszN NEP2cXlUSU6JRWK=
HCE-T cell MmjkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWDmSJY3UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1WtWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU42PjdzNDFOwG0> NFnWcFRUSU6JRWK=
HEL cell NW[2cXU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYrJcohq[mm2aX;uJI9nKGi3bXHuJGhGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OTBwNEe3OkDPxE1? MU\TRW5ITVJ?
EM-2 cell M3rNZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2fuZ2lvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFAxODFyN{ig{txO MXzTRW5ITVJ?
HT-144 cell MonBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHfrRlhKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUG0OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE42OzZyOTFOwG0> MWPTRW5ITVJ?
EW-16 cell NXizeHpZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFr3VoVKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlc3OTd6IN88US=> NWPKT45VW0GQR1XS
IA-LM cell M2H3N2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUDKeFN{UW6qaXLpeIlwdiCxZjDoeY1idiCLQT3MUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVIvPDR2NTFOwG0> M4DLRXNCVkeHUh?=
IST-MEL1 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFzjc3VKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3NSWwyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjF|NEWg{txO M1XHbHNCVkeHUh?=
IST-MES1 cell MlX0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnrETY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXTNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xQDV3MjFOwG0> MljtV2FPT0WU
GI-1 cell NV3nZ5hPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYf2UnRWUW6qaXLpeIlwdiCxZjDoeY1idiCJST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlM3OjJizszN M4rGbXNCVkeHUh?=
IST-SL2 cell NGfxTG5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEm5VmRKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPTB|MEKg{txO Ml65V2FPT0WU
JVM-2 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGpXVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1{LkO2Nlg1KM7:TR?= NWHKOZV{W0GQR1XS
JVM-3 cell MkPkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmfvTY5pcWKrdHnvckBw\iCqdX3hckBLXk1vMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;M{euNlM{QCEQvF2= NIfSRWxUSU6JRWK=
KALS-1 cell NUPCdY1VT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVLRdYg5UW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODl2OTFOwG0> NH;4PY9USU6JRWK=
KARPAS-422 cell M3fSW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHTKcYxKdmirYnn0bY9vKG:oIHj1cYFvKEuDUmDBV{01OjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwM{O5PVch|ryP NWfP[25VW0GQR1XS
JiyoyeP-2003 cell MmGwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVO4UFJWUW6qaXLpeIlwdiCxZjDoeY1idiCMaYnvfYVRNTJyMEOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuO|M1PjZizszN NIXaeGxUSU6JRWK=
KARPAS-45 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2X6Z2lvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQ2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF04NjVzNkexJO69VQ>? MWrTRW5ITVJ?
KGN cell MlXqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGDrPVFKdmirYnn0bY9vKG:oIHj1cYFvKEuJTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVk1OiEQvF2= NHrxclJUSU6JRWK=
KLE cell MnS2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnuUVNKdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVMyPyEQvF2= MXXTRW5ITVJ?
KNS-42 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnnlTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNlQ1OTJizszN NILoN29USU6JRWK=
KNS-81-FD cell NW\lZWR3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{TJSmlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUixMWZFKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0zOy5zNE[g{txO M3P5fXNCVkeHUh?=
KP-N-YS cell NVvWPHBwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYXJcohq[mm2aX;uJI9nKGi3bXHuJGtRNU5vWWOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGyMlkzQDNizszN MoTQV2FPT0WU
HOP-62 cell NXvh[GFQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF\BNXFKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOTh|NDFOwG0> NYPhdlFLW0GQR1XS
KURAMOCHI cell NE\0bZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUT1SWlLUW6qaXLpeIlwdiCxZjDoeY1idiCNVWLBUW9EUEliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEO0PFch|ryP NGLNUFhUSU6JRWK=
HUTU-80 cell NGT4XppIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGhWXFVvOECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|E1OiEQvF2= NVvRT5Z{W0GQR1XS
LAMA-84 cell M4HjfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{j2UmlvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMEOyNFch|ryP NIXiVZZUSU6JRWK=
LB1047-RCC cell M17X[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHLPTmdKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEC5PFg4KM7:TR?= MnT6V2FPT0WU
LB2518-MEL cell Mn;xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{LvUGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zNEG2NkDPxE1? NF\Cb4pUSU6JRWK=
LB373-MEL-D cell MmXVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4rMXmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ|N{OtUWVNNURiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwOEK1NFgh|ryP NYe5XGlIW0GQR1XS
LB771-HNC cell MmHES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGHDc21KdmirYnn0bY9vKG:oIHj1cYFvKEyEN{exMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:Oi53N{W1NUDPxE1? MX\TRW5ITVJ?
LB996-RCC cell NFjtS4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODl7MUKg{txO Mo[wV2FPT0WU
LC-2-ad cell NHGxO5dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGXURlVKdmirYnn0bY9vKG:oIHj1cYFvKEyFLUKtZYQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODJ3OE[g{txO MmjQV2FPT0WU
J-RT3-T3-5 cell M164V2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;J[ph[UW6qaXLpeIlwdiCxZjDoeY1idiCMLWLUN{1VOy13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD16Lkm2OVI6KM7:TR?= NXHzU4czW0GQR1XS
LP-1 cell NV\YNWRHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWXoU5pnUW6qaXLpeIlwdiCxZjDoeY1idiCOUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME23MlU1Pzh{IN88US=> NVq4W|JCW0GQR1XS
K-562 cell NYLCU242T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUDJcohq[mm2aX;uJI9nKGi3bXHuJGsuPTZ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwNFAxODJ4NU[g{txO NWDDPFFOW0GQR1XS
LS-123 cell NY[5[nBHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NImyTYtKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUGyN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yPDB4NDFOwG0> NILncGZUSU6JRWK=
K5 cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTrcVhKdmirYnn0bY9vKG:oIHj1cYFvKEt3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG2OFg6KM7:TR?= NYHab|RVW0GQR1XS
LS-411N cell NF[0UWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorZTY5pcWKrdHnvckBw\iCqdX3hckBNWy12MUHOJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20PE41PzR6IN88US=> MmnzV2FPT0WU
KG-1 cell NWPnU5Y2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIjFfGZKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUSuOlA5PDVizszN NV;xU|RZW0GQR1XS
KINGS-1 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml7mTY5pcWKrdHnvckBw\iCqdX3hckBMUU6JUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE3PjZ4IN88US=> NVvoZ2U4W0GQR1XS
LXF-289 cell NFrEcYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1rmbmlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOzl3NjFOwG0> MkO4V2FPT0WU
MC116 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3\Ne2lvcGmkaYTpc44hd2ZiaIXtZY4hVUNzMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVE1OSEQvF2= NXu5XYtQW0GQR1XS
KS-1 cell NIX6OG9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYC3[lg2UW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzPzNizszN NVf6dHhlW0GQR1XS
KU812 cell M{fPVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4Szd2lvcGmkaYTpc44hd2ZiaIXtZY4hU1V6MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVE5QDNizszN NYDpb5l7W0GQR1XS
MEG-01 cell NGDwT2dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEm0U4RKdmirYnn0bY9vKG:oIHj1cYFvKE2HRz2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMEm4NFUh|ryP NFyzcZdUSU6JRWK=
MFH-ino cell NF\3V4xIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4fzSmlvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDd{NDFOwG0> NWDSO4VnW0GQR1XS
L-540 cell MkSwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXfJcohq[mm2aX;uJI9nKGi3bXHuJGwuPTRyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zNT6wOlcyKM7:TR?= NHPpfo1USU6JRWK=
MHH-NB-11 cell NYfvWmlUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUfuWVBEUW6qaXLpeIlwdiCxZjDoeY1idiCPSFitUmIuOTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTR|LkC4NVgh|ryP M2D3THNCVkeHUh?=
MMAC-SF cell MnzlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIDUO3pKdmirYnn0bY9vKG:oIHj1cYFvKE2PQVOtV2Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvPzl|MEeg{txO NH7NVXRUSU6JRWK=
LB2241-RCC cell M3jlVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmjJTY5pcWKrdHnvckBw\iCqdX3hckBNSjJ{NEGtVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF06NjB{MEGyJO69VQ>? NHWyb5dUSU6JRWK=
LB831-BLC cell NE\ofFFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHXvN2xKdmirYnn0bY9vKG:oIHj1cYFvKEyEOEOxMWJNSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yNE[wPUDPxE1? Ml7YV2FPT0WU
MOLT-16 cell M1vnSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXrJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK5MlYzQTJizszN MXLTRW5ITVJ?
LC-1F cell NEDhRlBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV;mem9vUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2xSkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlcvOzJ2NTFOwG0> NGC0RVJUSU6JRWK=
MOLT-4 cell MkLhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFruVJBKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlYvPjd3MzFOwG0> MlqwV2FPT0WU
MZ1-PC cell MkHES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYHlVllZUW6qaXLpeIlwdiCxZjDoeY1idiCPWkGtVGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODNzMUmg{txO M1LIcHNCVkeHUh?=
MONO-MAC-6 cell M1P2SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2\ybWlvcGmkaYTpc44hd2ZiaIXtZY4hVU:QTz3NRWMuPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QC5{N{C2OkDPxE1? MXXTRW5ITVJ?
MZ2-MEL cell M{ftXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4K2PWlvcGmkaYTpc44hd2ZiaIXtZY4hVVp{LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4zQDV|NzFOwG0> NFmxRVNUSU6JRWK=
MPP-89 cell NFP6ZY5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVPxXItsUW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODRyNEmg{txO M2jydnNCVkeHUh?=
MZ7-mel cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYnJcohq[mm2aX;uJI9nKGi3bXHuJG1bPy2vZXygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuOFc6OTFizszN NHzhZ5FUSU6JRWK=
LOXIMVI cell M4jQTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGDsSJZKdmirYnn0bY9vKG:oIHj1cYFvKEyRWFnNWmkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOzF3MEOg{txO M2TUZnNCVkeHUh?=
NALM-6 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\TcGhOUW6qaXLpeIlwdiCxZjDoeY1idiCQQVzNMVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTl{OUWg{txO NYL3WGY2W0GQR1XS
NB13 cell NV3yRWZkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn23TY5pcWKrdHnvckBw\iCqdX3hckBPSjF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zOT60PFc4KM7:TR?= MmXZV2FPT0WU
NB5 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUHJcohq[mm2aX;uJI9nKGi3bXHuJG5DPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OS5|OUiyO{DPxE1? MWnTRW5ITVJ?
NB17 cell M3yxUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{XWWWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Mz62N|g1PyEQvF2= NYTl[|R{W0GQR1XS
NCCIT cell NYHvOmYzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;TPWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOFSWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUKuPFY3OTZizszN NXfVVnM4W0GQR1XS
NB69 cell MoXZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mkn0TY5pcWKrdHnvckBw\iCqdX3hckBPSjZ7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG0OFM3KM7:TR?= M3zBe3NCVkeHUh?=
NCI-H1304 cell M13BT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH:4bY1KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVMxPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OjhwMU[yPEDPxE1? M2nPRXNCVkeHUh?=
NCI-H1395 cell M13iVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlPOTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVQzNjBzNkOg{txO NVe1ZpY2W0GQR1XS
MHH-PREB-1 cell NFTPNWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn3qTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvUGLFRk0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjd2NE[5JO69VQ>? NXHJU5l{W0GQR1XS
MLMA cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkPBTY5pcWKrdHnvckBw\iCqdX3hckBOVE2DIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG0NFMzKM7:TR?= MlzDV2FPT0WU
MN-60 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEDrXFhKdmirYnn0bY9vKG:oIHj1cYFvKE2QLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xOU4yQTd7IN88US=> NG\DcGVUSU6JRWK=
MV-4-11 cell M2S1d2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYK4dld[UW6qaXLpeIlwdiCxZjDoeY1idiCPVj20MVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01NjN4NEW0JO69VQ>? NX;4UIxKW0GQR1XS
NB6 cell MlmzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVPteFNHUW6qaXLpeIlwdiCxZjDoeY1idiCQQk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUmuPVIzPTlizszN M2Pkb3NCVkeHUh?=
NCI-H1355 cell M3HYWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlrVTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzOVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTFyMkig{txO NWrDRmJRW0GQR1XS

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
phospho-c-Abl(Tyr245) / phospho-c-Src(Tyr416) ; 

PubMed: 23049975     


Protein levels of phosphorylated c-Abl (Tyr245), c-Abl, phosphorylated c-Src (Tyr416), c-Src, and GAPDH in NSC-34 cells overexpressing human wild-type or mutant SOD1s treated with various concentrations of dasatinib were measured by western blot. Cells were cultured in serum-free culture medium with doxycycline (Dox, 2 µg/ml), and western blot was performed at 24 h after dasatinib addition.

p27 / p21; 

PubMed: 20145167     


Dasatnib induced cell cycle arrest. Dasatinib induced growth arrest, shown as a cell cycle distribution graph in the lower panel, correlated with increased p27 and p21 levels. Western blotting for levels of p27 and p21 was performed on protein lysates of THP-1 cells treated for 48 hours with indicated doses of dasatinib or DMSO. Detection of actin served as control for comparable protein loading.

cleaved caspase 3 ; 

PubMed: 20145167     


Dasatinib induced apoptosis. Dasatinib causes apoptosis in Mo7e-KitD816H cells as detected by cleavage of caspase 3. Whole cell lysates were prepared after 24 hour treatment with dasatinib. Caspase 3 and cleaved capase 3 were analyzed by western blotting. Actin serves as loading control.

p-FAK/p-STAT3; 

PubMed: 23721490     


The effect of dasatinib in cell signalling. Western blot analysis with phosphorylated Src, FAK, Stat3, Akt and MAPK in HCC cell lines after 24 hours treatment of dasatinib. The cell lines were arranged according to their IC50 to dasatinib. The top three were most sensitive, the bottom 3 were least sensitive.

23049975 20145167 23721490
Growth inhibition assay
Cell viability; 

PubMed: 23721490     


9 HCC cell lines were exposed to the dedicated concentrations of dasatinib for 72 hours, and IC50 was tested by MTS. Results represent the mean (± SD) of three experiments.

23721490
Immunofluorescence
SRC / Met; 

PubMed: 26517812     


Immunocytochemistry of SRC and Met localization. Cellular localization of SRC and Met following treatment for 48 h with dasatinib, crizotinib or combination in A. LN-18 and B. U373 cells. Scale bar denotes 10 μm. Nuclei were visualized by DAPI while SRC and Met were labeled with a fluorescein and Texas-red conjugated secondary antibodies, respectively.

α-tubulin; 

PubMed: 26517812     


Combination of dasatinib and crizotinib impedes the formation of the α-tubulin-labeled mitotic spindle. LN-18 cells were treated with dasatinib 0.2 μM, crizotinib 4 μM or their combination for 48 h. Mitotic spindle were visualized using α-tubulin antibody conjugated to a fluorescein-labeled secondary antibody. Nuclei were stained by DAPI. The scale bar denotes 10 μm.

F-actin / Actinin-4 / Paxillin; 

PubMed: 31053734     


Conditionally immortalized differentiated podocytes treated for one-hour with 2 µM kinase inhibitor were stained for F-actin (phalloidin), α-actinin-4, paxillin, and nuclei (Hoechst 33342) to assess cytoskeletal and focal adhesion architecture (scale bars = 50 µm). Podocytes treated with dasatinib showed a marked decrease in cell-to-cell contacts, cell size and number of focal adhesions.

26517812 31053734
ELISA
TNF-α; 

PubMed: 17684099     


U937 cells were differentiated with vitamin D3, pretreated with the indicated concentrations of drugs for 1 h and stimulated with LPS for 6 h. TNF-α secretion was measured by ELISA. The graph shows the mean of two experiments done in duplicate.

E-selectin; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of E-selectin was determined using ELISA (n = 3, ±SEM).

VCAM-1; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of VCAM-1 was determined using ELISA (n = 3, ±SEM).

17684099 31110200
In vivo Dasatinib reverses splenomegaly in LMP2A/MYC double transgenic mice. Dasatinib specifically prevents colony formation by LMP2A expressing bone marrow B cells and decreased spleen size in the TgE mice. Spleen mass is significantly decreased among Dasatinib treated Tg6/λ-MYC mice when compared to the control group. Dasatinib inhibits lymphadenopathy in LMP2A/MYC double transgenic mice. Dasatinib reverses splenomegaly in Rag1KO mice engrafted with tumor cells from LMP2A/MYC double transgenic mice. Dasatinib therapy inhibits Lyn phosphorylation in B lymphocyte tumors expressing LMP2A. [3]

Protocol

Kinase Assay:

[1]

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Kinase autophosphorylation assays:

Kinase assays using wild-type and mutant glutathione S-transferase (GST)-Abl fusion proteins (c-Abl amino acids 220-498) are done. GST-Abl fusion proteins are released from glutathione-Sepharose beads before use; the concentration of ATP is 5 μM. Immediately before use in kinase autophosphorylation and in vitro peptide substrate phosphorylation assays, GST-Abl kinase domain fusion proteins are treated with LAR tyrosine phosphatase. After 1-hour incubation at 30 °C, LAR phosphatase is inactivated by addition of sodium vanadate (1 mM). Immunoblot analysis comparing untreated GST-Abl kinase to dephosphorylated GST-Abl kinase is routinely done using phosphotyrosine-specific antibody 4G10 to confirm complete (>95%) dephosphorylation of tyrosine residues and c-Abl antibody CST 2862 to confirm equal loading of GST-Abl kinase. The Dasatinib concentration range is extended to 1,000 nM for mutant T315I. These same inhibitor concentrations are used for the in vitro peptide substrate phosphorylation assays. The three inhibitors are tested over these same concentration ranges against GST-Src kinase and GST-Lyn kinase.
Cell Research:

[1]

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  • Cell lines: Ba/F3 cell lines
  • Concentrations: ~32 nM
  • Incubation Time: 72 hours
  • Method:

    Ba/F3 cell lines are seeded in triplicate and incubated with escalating concentrations of Dasatinib for 72 hours. Proliferation is measured using a methanethiosulfonate-based viability assay. IC50 and IC90 values are reported as the mean of three independent experiments done in quadruplicate. The inhibitor concentration ranges are 0 nM to 32 nM (Dasatinib). The Dasatinib concentration range is extended to 200 nM for mutant T315I.


    (Only for Reference)
Animal Research:

[3]

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  • Animal Models: EμLMP2A (TgE and Tg6 strains), MYC (λ-MYC), and LMP2A/λ-MYC double transgenic mice (Tg6/λ-MYC)
  • Dosages: 30 mg/kg
  • Administration: Administered via i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 21 mg/mL warmed (41.5 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+dd H2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 506.02
Formula

C22H28ClN7O3S

CAS No. 863127-77-9
Storage powder
in solvent
Synonyms BMS-354825 Monohydrate
Smiles CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04933526 Not yet recruiting Drug: Flumatinib|Drug: Dasatinib Chronic Myeloid Leukemia in Chronic Phase Shenzhen Second People''s Hospital July 1 2021 Phase 4
NCT04925648 Not yet recruiting Drug: Dasatinib|Drug: Darolutamide Metastatic Prostate Cancer St Vincent''s Hospital Sydney July 1 2021 Phase 2
NCT04063124 Recruiting Drug: Dasatinib + Quercetin Alzheimer Disease The University of Texas Health Science Center at San Antonio|Mayo Clinic February 14 2020 Phase 1|Phase 2
NCT04155411 Recruiting Drug: Dasatinib Dasatinib|BCR-ABL|Chronic Myeloid Leukemia Shenzhen Second People''s Hospital December 1 2019 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Frequently Asked Questions

  • Question 1:

    What’s the difference between S1021 and S7782?

  • Answer:

    Usually, hydrate will be more stable and dissolve better than free base. But this compound (S1021) dissolves better in DMSO than hydrate one (S7782).

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID