Dasatinib Monohydrate

Catalog No.S7782 Synonyms: BMS-354825 Monohydrate

Dasatinib Monohydrate Chemical Structure

Molecular Weight(MW): 506.02

Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.

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Cited by 66 Publications

Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
Targets
Abl [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
c-Kit (D816V) [2]
(Cell-free assay)
c-Kit (wt) [2]
(Cell-free assay)
0.6 nM 0.8 nM 37 nM 79 nM
In vitro

Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I. Dasatinib has a two-log (∼325-fold) increased potency relative to imatinib. Dasatinib potently inhibits wild-type Abl kinase and all mutants except T315I over a narrow range. Dasatinib directly targets wild-type and mutant Abl kinase domains and inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner. Dasatinib displays 325-fold greater potency compared with imatinib against cells expressing wild-type Bcr-Abl. [1] The percent of colonies of TgE bone marrow cells are decreased from 100% in untreated wells to 4.12% in Dasatinib treated wells. In the presence of Dasatinib, the difference in the percentage of colonies formed by WT and TgE bone marrow cells is statistically significant. Expression of LMP2A is able to promote B lymphocyte survival and proliferation, which can be inhibited by targeting Lyn and/or c-Abl kinases through Dasatinib. [3] Dasatinib treatment inhibits Src signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer cells. Treatment with increasing doses of Dasatinib (0.019 μM to 1.25 μM) for 3 days inhibits the growth of the C643, TPC1, BCPAP, and SW1736 cell lines by about 50% at low nanomolar concentrations, while higher concentrations are required to inhibit the growth of the K1 cell line. Treatment with 10 nM or 50 nM Dasatinib results in a 9-22% increase of cells in the G1 population among BCPAP and SW1736 and K1 cells, and a corresponding 7-18% decrease in the percentage of cells in the S phase. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K562 cell M{LvWHBzd2yrZnXyZZRqd25iYYPzZZk> M{eydFczKGh? NGTP[nZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODBzIN88US=> M4nhNFE2PjF3NUGy
WiDr cell MkDXVJJwdGmoZYLheIlwdiCjc4PhfS=> MWq3NkBp NHTZPYdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGfpSJIh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODV{IN88US=> NVzMfnVzOTV4MUW1NVI>
PC3 cell NXLHbJc{WHKxbHnm[ZJifGmxbjDhd5NigQ>? MkfkO|IhcA>? NY[4UlF6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODB7NDFOwG0> NYDhcXA3OTV4MUW1NVI>
MDA-MB-231 cell MlzjVJJwdGmoZYLheIlwdiCjc4PhfS=> NVzVelNLPzJiaB?= NFzr[GxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= MYSxOVYyPTVzMh?=
M07ep210 cell NF;sdpJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFf3VII1QCCq M2jicmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG0xP2WyMkGwJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCdM1jdeIh6dWmmaX7lJJVxfGGtZTDhd5NigSxiSVO1NF0xNjB5IH7N MXuxO|k2PjB6MB?=
K562 cell M3vPdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLFdJI1QCCq Mo[4S5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgX|NJZXSqeX3p[Ilv\SC3cIThb4Uh[XO|YYmsJGlEPTB;MD6wNFEh|ryP MVWxO|k2PjB6MB?=
M07e cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3T3WVQ5KGh? M3jLW2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG0xP2ViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHs{UF22aIntbYRqdmVidYD0ZYtmKGG|c3H5MEBKSzVyPUCuNFAyOiEQvF2= NGSwXWwyPzl3NkC4NC=>
K562 cell MoDsR5l1d3SxeHnjbZR6KGG|c3H5 NIHOenE4OiCq MYPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDXV3QuQCC{ZXHn[Y51KGKjc3XkJG1VXCCjc4PhfUwhUUN3ME2xNk45OyEQvF2= Mn\zNlIzOTd6N{e=
U937 cell MU\DfZRwfG:6aXPpeJkh[XO|YYm= M3\IV|czKGh? NHHJV|BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQTN5IHPlcIx{KGGodHXyJFczKGi{czDifUBYW1RvODDy[YFo\W62IHLhd4VlKE2WVDDhd5NigSxiSVO1NF0yOy54MzFOwG0> NY[wRoxbOjJ{MUe4O|c>
K562 cell NXz5[ZJvWHKxbHnm[ZJifGmxbjDhd5NigQ>? NUPnXYd7PzJiaB?= NYXtXFBGSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDDR2s5KGG|c3H5MEBKSzVyPUCuO{BvVQ>? MV[yN|UzOTB{MB?=
MDA-MB-435S cell MWPQdo9tcW[ncnH0bY9vKGG|c3H5 MXS3NkBp MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk01OzWVIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9N{46KM7:TR?= MkjZNlM2OjFyMkC=
NCI-H460 cell NVn6XJhGWHKxbHnm[ZJifGmxbjDhd5NigQ>? MX:3NkBp NUi4b293SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDR4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVgvQTlizszN MWmyN|UzOTB{MB?=
NCI-H23 cell MoXRVJJwdGmoZYLheIlwdiCjc4PhfS=> NIjqeYI4OiCq NV7jXVZESW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDJ|IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9Nk4zPyEQvF2= MUCyN|UzOTB{MB?=
A549 cell NVXRRWQ2WHKxbHnm[ZJifGmxbjDhd5NigQ>? M2jxUVczKGh? MoXTRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDNUS5JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVA:OTJwNk[g{txO NX3PZWg6OjN3MkGwNlA>
T47D cell NUPMdWVTWHKxbHnm[ZJifGmxbjDhd5NigQ>? NWTPS2RJPzJiaB?= MoTsRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCWNEfEJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVA:OC57IN88US=> MXyyN|UzOTB{MB?=
HCT116 cell MoDQVJJwdGmoZYLheIlwdiCjc4PhfS=> M2\N[lczKGh? M4njPGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSFPUNVE3KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;Mj6zJO69VQ>? M37OfVI{PTJzMEKw
MCF7 cells M4GwUXBzd2yrZnXyZZRqd25iYYPzZZk> NV\5RlgyPzJiaB?= MnjyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVA:Oi53NzFOwG0> NWLmRpM1OjN3MkGwNlA>
RXF 393NL cell NHPpOGREgXSxdH;4bYNqfHliYYPzZZk> MUK0JIRigXN? MX3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDSXGYhOzl|TlygZ4VtdHNiYX\0[ZIhPCCmYYnzJIJ6KHC{b4Dp[Il2dSCrb3Tp[IUhe3SjaX7pcoctKEmFNUC9NlEvPyCwTR?= MWSyN|I2OzB5NB?=
PRXF DU145 cell Ml:1R5l1d3SxeHnjbZR6KGG|c3H5 NXXHellXPCCmYYnz MnHER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVHJZTiCGVUG0OUBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF0xNjB4MkOg{txO M2CyN|I{OjV|MEe0
LXFA 983L cell MUHDfZRwfG:6aXPpeJkh[XO|YYm= M3G5bFQh\GG7cx?= NH3Ye5ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNYE[DIEm4N2wh[2WubIOgZYZ1\XJiNDDkZZl{KGK7IIDyc5Bq\Gm3bTDpc4Rq\GVic4ThbY5qdmduIFnDOVA:PTZwNTDuUS=> NX7YeXRuOjN{NUOwO|Q>
GXF251L cell MljSR5l1d3SxeHnjbZR6KGG|c3H5 M3rud|Qh\GG7cx?= NEHuRoFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBIYEZ{NUHMJINmdGy|IHHmeIVzKDRiZHH5d{BjgSCycn;wbYRqfW1iaX;kbYRmKHO2YXnubY5oNCCLQ{WwQVIvOjVizszN NVfQTFNFOjN{NUOwO|Q>
CXF 1103L cell NWfTVGRPS3m2b4TvfIlkcXS7IHHzd4F6 M{nmeVQh\GG7cx?= MVfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDXGYhOTFyM1ygZ4VtdHNiYX\0[ZIhPCCmYYnzJIJ6KHC{b4Dp[Il2dSCrb3Tp[IUhe3SjaX7pcoctKEmFNUC9OE4{PiEQvF2= NYLVd2M3OjN{NUOwO|Q>
PAXF 1657L cell MWLDfZRwfG:6aXPpeJkh[XO|YYm= NX31[IRpPCCmYYnz NWS0NlB3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEG[RjCxOlU4VCClZXzsd{Bi\nSncjC0JIRigXNiYomgdJJweGmmaYXtJIlw\GmmZTDzeIFqdmmwZzygTWM2OD1yLkGyNUDPxE1? NXrrTmFSOjN{NUOwO|Q>
NCI-H1648 cell Moe5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUDNdZhQUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE3PDhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCyNFEyKM7:TR?= MojYV2FPT0WU
NCI-H1838 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rxd2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixPFM5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5|MEezN{DPxE1? MYLTRW5ITVJ?
NCI-H2126 cell NEDuR2JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvQDd3NUKg{txO NX3De|NHW0GQR1XS
NCI-H2141 cell MmTYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkG0NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd5NUSg{txO M13jNXNCVkeHUh?=
NCI-H2107 cell NHPjS2tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGwO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ{NjR6NEeg{txO NH\SZoxUSU6JRWK=
NCI-H747 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWTJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDN4MjFOwG0> M2nGenNCVkeHUh?=
NCI-H720 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvhTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEeyNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjJ5M{Og{txO NIjUdo5USU6JRWK=
NKM-1 cell M1jU[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG5MVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLkOwPFU6KM7:TR?= M{HNSnNCVkeHUh?=
NMC-G1 cell NULHfVRpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYXJcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVYxPiEQvF2= NEDsOXZUSU6JRWK=
NTERA-S-cl-D1 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPsTY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkGyNlg{KM7:TR?= Mom1V2FPT0WU
OCI-AML2 cell MoXCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mnn4TY5pcWKrdHnvckBw\iCqdX3hckBQS0lvQV3MNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OU45PjF3NDFOwG0> NUixU|A2W0GQR1XS
OCUB-M cell NELa[29Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETHe|NKdmirYnn0bY9vKG:oIHj1cYFvKE:FVVKtUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4xPDRzMjFOwG0> NHzxdnNUSU6JRWK=
OPM-2 cell M4HhR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFj6cnFKdmirYnn0bY9vKG:oIHj1cYFvKE:STT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20MlI4Pjh3IN88US=> NUDqV|lRW0GQR1XS
OS-RC-2 cell M{PYWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\VN2lvcGmkaYTpc44hd2ZiaIXtZY4hV1NvUlOtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjB|IN88US=> NIO0SVFUSU6JRWK=
ONS-76 cell M4PCPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4TtTGlvcGmkaYTpc44hd2ZiaIXtZY4hV06VLUe2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlQzQTVzIN88US=> MVHTRW5ITVJ?
OVCAR-4 cell NE[xUnlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXnsSJVmUW6qaXLpeIlwdiCxZjDoeY1idiCRVlPBVk01KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjN5NEOzJO69VQ>? MUXTRW5ITVJ?
NCI-H446 cell MnTuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33oWWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi0OFYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPjJ5NjFOwG0> MmrqV2FPT0WU
NCI-H510A cell NUfCd3RNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MojVTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWxNGEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVE6NjN7N{Og{txO M2K4O3NCVkeHUh?=
PF-382 cell M13HVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXq1TnNZUW6qaXLpeIlwdiCxZjDoeY1idiCSRj2zPFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTd4N{ig{txO Ml;HV2FPT0WU
NCI-H64 cell MlzRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3z5d2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi2OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlkvPjJ3MzFOwG0> NEXSO5pUSU6JRWK=
PSN1 cell MlrmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NG\WS2FKdmirYnn0bY9vKG:oIHj1cYFvKFCVTkGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFQ1PzRizszN NG\Oc3JUSU6JRWK=
QIMR-WIL cell NXHEW5I3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJHFKVVJvV1nMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlcxPjJ7IN88US=> MULTRW5ITVJ?
RL95-2 cell M2D4NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmXpTY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVA{QCEQvF2= NHS4NoJUSU6JRWK=
RCC10RGB cell M1LZemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHJESzFyUlfCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlQ6OTFizszN NF3TNo9USU6JRWK=
RKO cell NYX5NnJGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1XSOmlvcGmkaYTpc44hd2ZiaIXtZY4hWkuRIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkWyPVY3KM7:TR?= Mm\GV2FPT0WU
NCI-SNU-16 cell M{foT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU\N[IttUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtV25WNTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD16LkW2NVI5KM7:TR?= MlzUV2FPT0WU
RPMI-6666 cell M3T0Wmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXvWNJRqUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVY3PjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTdwMkewOlch|ryP NH3nU2xUSU6JRWK=
NEC8 cell M1LpeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlHRTY5pcWKrdHnvckBw\iCqdX3hckBPTUN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12ND6zN|Yh|ryP NEi5dmxUSU6JRWK=
RS4-11 cell NWWzPGtPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfnfHFSUW6qaXLpeIlwdiCxZjDoeY1idiCUU{StNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVcvPjV5OEeg{txO MUnTRW5ITVJ?
RXF393 cell NYjZdZBlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MofFTY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFI{PTdizszN Mli1V2FPT0WU
Raji cell M4HSNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYPJcohq[mm2aX;uJI9nKGi3bXHuJHJicmliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTF|Lke0PVch|ryP MYjTRW5ITVJ?
NOS-1 cell NIX2dINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwOlEzQSEQvF2= MVHTRW5ITVJ?
SBC-1 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1Kz[GlvcGmkaYTpc44hd2ZiaIXtZY4hW0KFLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuOVc6QDRizszN NHvqOHBUSU6JRWK=
SF126 cell Ml\0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmDBTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6zOVQyKM7:TR?= NWDFRnVCW0GQR1XS
SF539 cell NXHBO5dUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUPJcohq[mm2aX;uJI9nKGi3bXHuJHNHPTN7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMz64OVU4KM7:TR?= MVLTRW5ITVJ?
SH-4 cell NX7K[YFPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXrhOlVYUW6qaXLpeIlwdiCxZjDoeY1idiCVSD20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE5PDF|IN88US=> MYrTRW5ITVJ?
OMC-1 cell NEe5ZnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGK2dIdKdmirYnn0bY9vKG:oIHj1cYFvKE:PQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yO{4yPDJ{IN88US=> MmXwV2FPT0WU
SIG-M5 cell Mn\kS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXjZTI9yUW6qaXLpeIlwdiCxZjDoeY1idiCVSVetUVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVkvODJ2OUOg{txO MX\TRW5ITVJ?
SJSA-1 cell M37MZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFL3N|dKdmirYnn0bY9vKG:oIHj1cYFvKFOMU1GtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9PE44OjhyNTFOwG0> NXy3TlJWW0GQR1XS
SK-LMS-1 cell M1\ZSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3zUdmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVMvOTF6OE[g{txO MXXTRW5ITVJ?
SK-NEP-1 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVzEeHNrUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3OSXAuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QC56OUG1OUDPxE1? M1LKUnNCVkeHUh?=
SKM-1 cell NHX6e3hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJHNMVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD17LkCxO|M1KM7:TR?= NFjsbmRUSU6JRWK=
SK-PN-DW cell M{\NT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHrOcJVKdmirYnn0bY9vKG:oIHj1cYFvKFONLWDOMWRYKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{Pi5zOUSzJO69VQ>? MXvTRW5ITVJ?
SK-UT-1 cell M{DsNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXPJcohq[mm2aX;uJI9nKGi3bXHuJHNMNVWWLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUKuNVY3QTNizszN M4e1cHNCVkeHUh?=
SNB75 cell M2e4SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHnGZotKdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1PDN3IN88US=> MmXzV2FPT0WU
REH cell M4[wXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlntTY5pcWKrdHnvckBw\iCqdX3hckBTTUhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTJyLk[zOVch|ryP MmG3V2FPT0WU
SNU-C2B cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnETYdJUW6qaXLpeIlwdiCxZjDoeY1idiCVTmWtR|JDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yNjNyNUi5JO69VQ>? MlzFV2FPT0WU
RPMI-8866 cell M1;ocGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVTJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvOEi2OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVcvPDR3NTFOwG0> MU\TRW5ITVJ?
SW872 cell NX3p[FZ4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1j6OWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFQyPjFizszN NFPHNopUSU6JRWK=
SW962 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkTGTY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVI6OiEQvF2= NGP3VIZUSU6JRWK=
SF268 cell NH\4dGdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVfJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjZ6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG3OFA1KM7:TR?= NXzTS3hUW0GQR1XS
TE-1 cell Mof3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3PXTmlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNFU1KM7:TR?= M3znPHNCVkeHUh?=
8-MG-BA cell NXvyWXVZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoHTTY5pcWKrdHnvckBw\iCqdX3hckA5NU2JLVLBJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE2PDV6IN88US=> M1TjdnNCVkeHUh?=
A101D cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXjJcohq[mm2aX;uJI9nKGi3bXHuJGEyODGGIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLkCzNFQ{KM7:TR?= M33oPXNCVkeHUh?=
A253 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYe5UZVoUW6qaXLpeIlwdiCxZjDoeY1idiCDMkWzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zMlc{OjR4IN88US=> MofNV2FPT0WU
A3-KAW cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUHJcohq[mm2aX;uJI9nKGi3bXHuJGE{NUuDVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD65PFQ2OiEQvF2= NGqzT5FUSU6JRWK=
A4-Fuk cell NVfLZlZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEDhcGhKdmirYnn0bY9vKG:oIHj1cYFvKEF2LV\1b{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|gvOTByOTFOwG0> M2\2eHNCVkeHUh?=
A388 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXXMeXVnUW6qaXLpeIlwdiCxZjDoeY1idiCDM{i4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA2ODl3IN88US=> M1ztNXNCVkeHUh?=
ACN cell NFjq[JBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYL3UIp7UW6qaXLpeIlwdiCxZjDoeY1idiCDQ16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuPFIzPTJizszN NFP0PVhUSU6JRWK=
A704 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2HMcGlvcGmkaYTpc44hd2ZiaIXtZY4hSTdyNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVQ6OSEQvF2= MnLUV2FPT0WU
ALL-PO cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYPHd4dyUW6qaXLpeIlwdiCxZjDoeY1idiCDTFytVG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVExNjd7M{ig{txO NVzwdG9wW0GQR1XS
ARH-77 cell M2fpW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NULHNZVCUW6qaXLpeIlwdiCxZjDoeY1idiCDUlitO|ch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVMvPDZ7MUWg{txO M2fUSnNCVkeHUh?=
SR cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGXUXYdKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12LkS5PVU1KM7:TR?= MkPvV2FPT0WU
BB65-RCC cell NGrIdFRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX7G[25{UW6qaXLpeIlwdiCxZjDoeY1idiCEQk[1MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yOEKyO{DPxE1? MYLTRW5ITVJ?
BB49-HNC cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUjJcohq[mm2aX;uJI9nKGi3bXHuJGJDPDlvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlM5PTl7IN88US=> M4qzOnNCVkeHUh?=
BC-1 cell MoXNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWO4VlNtUW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yPE43PTFizszN NH7jPVBUSU6JRWK=
BC-3 cell M3KwPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLuVWJKdmirYnn0bY9vKG:oIHj1cYFvKEKFLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGyMlEyOzhizszN M3rvPHNCVkeHUh?=
BL-41 cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWTJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTRzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkK5NVI{KM7:TR?= NI\u[4dUSU6JRWK=
BL-70 cell NFzYNI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFHBXpVKdmirYnn0bY9vKG:oIHj1cYFvKEKOLUewJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxODByMEiyNVgh|ryP NUjlZYwyW0GQR1XS
SW684 cell NFWzb2JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkO0PVgh|ryP M13GdHNCVkeHUh?=
BOKU cell M1\GPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2ThVGlvcGmkaYTpc44hd2ZiaIXtZY4hSk:NVTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD60PVE{OyEQvF2= NWe3O2llW0GQR1XS
SW954 cell Mn\tS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEHxXFVKdmirYnn0bY9vKG:oIHj1cYFvKFOZOUW0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzQTJ5IN88US=> NGSwRVhUSU6JRWK=
C2BBe1 cell NX\GXVNXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX7yZWliUW6qaXLpeIlwdiCxZjDoeY1idiCFMlLC[VEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODh|MEig{txO MmmxV2FPT0WU
BV-173 cell NFrjRWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnX2TY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFAxODByMUC5JO69VQ>? NWG3cVFGW0GQR1XS
Becker cell NHm2NHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHXPdGlKdmirYnn0bY9vKG:oIHj1cYFvKEKnY3vldkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOzByMzFOwG0> M17ubXNCVkeHUh?=
SW982 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1vvZWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7OEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFEyOTVizszN MYPTRW5ITVJ?
697 cell M3LvUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUH6WGt2UW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVk6QDdizszN NUToOWI4W0GQR1XS
TE-15 cell MknJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmS1TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFU5QTFizszN MUnTRW5ITVJ?
TE-11 cell M2nwc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH7vWWNKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA4QDV6IN88US=> MmXrV2FPT0WU
TE-5 cell NFHFUIpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWP3TmxpUW6qaXLpeIlwdiCxZjDoeY1idiCWRT21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlc6OTN7IN88US=> NVfY[3FHW0GQR1XS
TE-6 cell M1nEcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYjJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwMkGyNlYh|ryP MV;TRW5ITVJ?
TE-9 cell MkfVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4K1dGlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD64O|U{OiEQvF2= NIDhT3FUSU6JRWK=
TGBC24TKB cell M17WTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVrJcohq[mm2aX;uJI9nKGi3bXHuJHRISkN{NGTLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDd4MTFOwG0> MW\TRW5ITVJ?
TGW cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2nFU2lvcGmkaYTpc44hd2ZiaIXtZY4hXEeZIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMT6yPFI5KM7:TR?= Mo[yV2FPT0WU
TK10 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVfJcohq[mm2aX;uJI9nKGi3bXHuJHRMOTBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEGxO|Qh|ryP NXjjfVJRW0GQR1XS
TGBC1TKB cell MYrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rPNGlvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{HUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODZzNkSg{txO MUXTRW5ITVJ?
A498 cell M{XWfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2TuW2lvcGmkaYTpc44hd2ZiaIXtZY4hSTR7ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wO|I5PCEQvF2= MVLTRW5ITVJ?
UACC-257 cell NXy0ZXI{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFHRVldKdmirYnn0bY9vKG:oIHj1cYFvKFWDQ1OtNlU4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yOi57MUm4JO69VQ>? NWXZTmh7W0GQR1XS
U-87-MG cell MnjQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYLLPHFOUW6qaXLpeIlwdiCxZjDoeY1idiCXLUi3MW1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{OC55Nk[g{txO MVvTRW5ITVJ?
BB30-HNC cell NYS5XlBUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NELIOVRKdmirYnn0bY9vKG:oIHj1cYFvKEKEM{CtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB3NEO3JO69VQ>? MVvTRW5ITVJ?
no-10 cell Mk\2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHjBcG5KdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlMyQTNzIN88US=> M3fvXHNCVkeHUh?=
CAS-1 cell NHHiXmhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXfJcohq[mm2aX;uJI9nKGi3bXHuJGNCWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLkSwPVkzKM7:TR?= M1fY[3NCVkeHUh?=
CGTH-W-1 cell NF\EV3RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXjJcohq[mm2aX;uJI9nKGi3bXHuJGNIXEhvVz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{PTR6IN88US=> NH7tSW1USU6JRWK=
TE-10 cell Mmq4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnnVTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wOlM2PyEQvF2= NFjueGFUSU6JRWK=
COLO-684 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vNki0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20Ok4zOjV6IN88US=> NIPyN3JUSU6JRWK=
TE-12 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVfkOoRIUW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOTh4MTFOwG0> M{PobHNCVkeHUh?=
COR-L279 cell MmLkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEXHOIhKdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01OC5{OEWyJO69VQ>? NFrtW|ZUSU6JRWK=
TE-8 cell NUGzT2w5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWf2emZnUW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyPTd4IN88US=> MYrTRW5ITVJ?
CP66-MEL cell M4TONWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYL0XlNqUW6qaXLpeIlwdiCxZjDoeY1idiCFUE[2MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zOUWzNUDPxE1? MkP1V2FPT0WU
CTV-1 cell M3flSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYHsfolUUW6qaXLpeIlwdiCxZjDoeY1idiCFVG[tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByNECzOkDPxE1? NV7ucFVzW0GQR1XS
VA-ES-BJ cell M4L1cmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkHYTY5pcWKrdHnvckBw\iCqdX3hckBXSS2HUz3CTkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOzlyMjFOwG0> MoG1V2FPT0WU
D-263MG cell M4CxN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV;WN4NqUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK2N21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjN4MkK0JO69VQ>? MX\TRW5ITVJ?
D-336MG cell MkHSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXfsO3pqUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjByNkK5PEDPxE1? M4rHR3NCVkeHUh?=
D-502MG cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{fRSmlvcGmkaYTpc44hd2ZiaIXtZY4hTC13MELNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4zOzN5NjFOwG0> MUjTRW5ITVJ?
DJM-1 cell M{nQSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlfuTY5pcWKrdHnvckBw\iCqdX3hckBFUk1vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Nj60PFU2QCEQvF2= MXvTRW5ITVJ?
no-11 cell NXXzSXRPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYDJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkWwNlI5KM7:TR?= NVLnc4FtW0GQR1XS
DMS-153 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;KdW41UW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVU{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yPC5yMEK4JO69VQ>? NGDkZ|hUSU6JRWK=
DSH1 cell NETvRWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJGRUUDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMkSwNFEh|ryP M3\aR3NCVkeHUh?=
DU-4475 cell NYTRdGhkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXnJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUiuNlE3PTJizszN M3jKTXNCVkeHUh?=
EB-3 cell MlvGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJGVDNTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTN2LkOxNVgh|ryP MnryV2FPT0WU
EHEB cell MnHzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUPFNmV2UW6qaXLpeIlwdiCxZjDoeY1idiCHSFXCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNE4xPjV4IN88US=> MmLHV2FPT0WU
COLO-829 cell NYHCVm1ST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGjFWZRKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tPFI6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjF{MkGzJO69VQ>? MVnTRW5ITVJ?
CP67-MEL cell M3zGWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGNRPjdvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlIxPDh6IN88US=> NGrle5dUSU6JRWK=
ES8 cell NFnSW4FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXqwUVFMUW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOyMlEzPTJizszN NGrjSm5USU6JRWK=
EVSA-T cell M4LSOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2rXVmlvcGmkaYTpc44hd2ZiaIXtZY4hTV[VQT3UJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME25MlI4Pzl|IN88US=> MlryV2FPT0WU
ES4 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\kNmV1UW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNFUyPDVizszN MmL2V2FPT0WU
ETK-1 cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWfhPFFDUW6qaXLpeIlwdiCxZjDoeY1idiCHVFutNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjh|MjFOwG0> M4H4cXNCVkeHUh?=
ES6 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXLJVpZtUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFMyQTNizszN NWf1bGFVW0GQR1XS
EW-24 cell M1TUemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mnz6TY5pcWKrdHnvckBw\iCqdX3hckBGXy1{NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD63PFE3PSEQvF2= MVnTRW5ITVJ?
EoL-1-cell cell NHnYUWJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGXQd4JKdmirYnn0bY9vKG:oIHj1cYFvKEWxTD2xMYNmdGxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMECwNFE{ODlizszN MoDpV2FPT0WU
Calu-6 cell NWPQbnU3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7VRoJKdmirYnn0bY9vKG:oIHj1cYFvKEOjbIWtOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N{4xPTd2MTFOwG0> M2HDRXNCVkeHUh?=
GAK cell Mk\ZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV7qNIYxUW6qaXLpeIlwdiCxZjDoeY1idiCJQVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOxMlI3QDZizszN MnXwV2FPT0WU
D-247MG cell M1PNTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVnueHl5UW6qaXLpeIlwdiCxZjDoeY1idiCGLUK0O21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF03NjF{NUG5JO69VQ>? NXLQUG9GW0GQR1XS
GB-1 cell NV;tXJZUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{fvcWlvcGmkaYTpc44hd2ZiaIXtZY4hT0JvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNlE2PyEQvF2= NFWyOlNUSU6JRWK=
GI-ME-N cell NHTNZ|JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NISyWlVKdmirYnn0bY9vKG:oIHj1cYFvKEeLLV3FMW4h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODZzMUig{txO MnTPV2FPT0WU
GCIY cell NGq1R|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUiwXIE5UW6qaXLpeIlwdiCxZjDoeY1idiCJQ1nZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA6PjV4IN88US=> NXTYeJU5W0GQR1XS
GT3TKB cell M4LkR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXHxZnZjUW6qaXLpeIlwdiCxZjDoeY1idiCJVEPUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVkvOzV3NE[g{txO MWHTRW5ITVJ?
HC-1 cell NYPuOHJXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI[wUJJKdmirYnn0bY9vKG:oIHj1cYFvKEiFLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK0MlU2PTFizszN NYqzTotxW0GQR1XS
HAL-01 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MonnTY5pcWKrdHnvckBw\iCqdX3hckBJSUxvMEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUG5Mlc2PDNizszN NX;yOGd2W0GQR1XS
HCC1187 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\L[2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMUG4O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|UvQDB3MjFOwG0> M1PoenNCVkeHUh?=
DEL cell Ml7DS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NILkS4tKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;NEGuPVA5PiEQvF2= NEHWW|BUSU6JRWK=
HCC1599 cell NInEdmJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGhESzF3OUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOyMlM{OjVizszN M2\yeXNCVkeHUh?=
DOHH-2 cell NFjxTXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DzeGlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyPzF7IN88US=> M2HOUnNCVkeHUh?=
HCC2157 cell Mo\HS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NW[wXmRXUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OyNVU4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{Py57OUS2JO69VQ>? NYOzO2loW0GQR1XS
HCE-4 cell NFXTVYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX;SV2dsUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1WtOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4zPjR|OTFOwG0> MmPiV2FPT0WU
HCE-T cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NE\jO5dKdmirYnn0bY9vKG:oIHj1cYFvKEiFRT3UJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlU3PzF2IN88US=> NUnYNY9LW0GQR1XS
HEL cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2fOOmlvcGmkaYTpc44hd2ZiaIXtZY4hUEWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMD60O|c3KM7:TR?= MmHHV2FPT0WU
EM-2 cell Ml75S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWH2c|ZjUW6qaXLpeIlwdiCxZjDoeY1idiCHTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxODByMUC3PEDPxE1? NUfBcJl5W0GQR1XS
HT-144 cell M2n4dGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUfSUnBxUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPTN4MEmg{txO NV;3ZlBUW0GQR1XS
EW-16 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mmf0TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD63OlE4QCEQvF2= NV;LPWhjW0GQR1XS
IA-LM cell Mlr1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJGlCNUyPIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMj60OFQ2KM7:TR?= M2\iS3NCVkeHUh?=
IST-MEL1 cell NVzNdlRkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3v6WWlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTN2NTFOwG0> Mmm4V2FPT0WU
IST-MES1 cell NVz3Xno4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2XWbmlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FV|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODh3NUKg{txO MWLTRW5ITVJ?
GI-1 cell M1;6Rmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEnKboVKdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuN|YzOiEQvF2= M2j0WXNCVkeHUh?=
IST-SL2 cell NILMdldIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoK3TY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlUxOzB{IN88US=> MXvTRW5ITVJ?
JVM-2 cell MmLYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MljvTY5pcWKrdHnvckBw\iCqdX3hckBLXk1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Mj6zOlI5PCEQvF2= NHH1WJNUSU6JRWK=
JVM-3 cell NFuyfWVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXrq[4M{UW6qaXLpeIlwdiCxZjDoeY1idiCMVl2tN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|cvOjN|ODFOwG0> MnriV2FPT0WU
KALS-1 cell NUXISmw3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUS4Z2duUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODl2OTFOwG0> NIjZeI5USU6JRWK=
KARPAS-422 cell NX:5XmZzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV;DdZB3UW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkOzPVk4KM7:TR?= NY\0PFVVW0GQR1XS
JiyoyeP-2003 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlTFTY5pcWKrdHnvckBw\iCqdX3hckBLcXmxeXXQMVIxODNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwN{O0OlYh|ryP MmPQV2FPT0WU
KARPAS-45 cell MnuyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVrJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9O{42OTZ5MTFOwG0> Mkm4V2FPT0WU
KGN cell NWTnTHE4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXriV3lWUW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFE6PDJizszN M3n2RXNCVkeHUh?=
KLE cell NVW3NlNKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIm2bWZKdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVMyPyEQvF2= MULTRW5ITVJ?
KNS-42 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXe3R4Y{UW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVEvOjR2MUKg{txO MkPrV2FPT0WU
KNS-81-FD cell MoCzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWTJcohq[mm2aX;uJI9nKGi3bXHuJGtPWy16MT3GSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlMvOTR4IN88US=> NV7JPIV4W0GQR1XS
KP-N-YS cell MnfwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmPlTY5pcWKrdHnvckBw\iCqdX3hckBMWC2QLWnTJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNk46Ojh|IN88US=> MVTTRW5ITVJ?
HOP-62 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M16xXWlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyQDN2IN88US=> M37BRXNCVkeHUh?=
KURAMOCHI cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LaOmlvcGmkaYTpc44hd2ZiaIXtZY4hU1WUQV3PR2hKKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB|NEi3JO69VQ>? NHzrenJUSU6JRWK=
HUTU-80 cell NIDDfGpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NID0VnFKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOzF2MjFOwG0> MnXWV2FPT0WU
LAMA-84 cell NVXKNYhVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHfrc3ZKdmirYnn0bY9vKG:oIHj1cYFvKEyDTVGtPFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODByMECzNlA4KM7:TR?= NUnT[pRoW0GQR1XS
LB1047-RCC cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkfLTY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjByOUi4O{DPxE1? Ml[1V2FPT0WU
LB2518-MEL cell M1\jbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFfHdZZKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkWxPE1OTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUSxOlIh|ryP M{nuUHNCVkeHUh?=
LB373-MEL-D cell NFnlc2xIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHXhb45KdmirYnn0bY9vKG:oIHj1cYFvKEyEM{ezMW1GVC2GIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkiyOVA5KM7:TR?= M33acXNCVkeHUh?=
LB771-HNC cell Mn\PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVXU[o9CUW6qaXLpeIlwdiCxZjDoeY1idiCOQke3NU1JVkNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTJwNUe1OVEh|ryP M4nRTnNCVkeHUh?=
LB996-RCC cell M3P0fGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmPCTY5pcWKrdHnvckBw\iCqdX3hckBNSjl7Nj3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODB7OUGyJO69VQ>? NXnP[W5nW0GQR1XS
LC-2-ad cell NXW4[WxsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGxENTJvYXSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFI2QDZizszN Mm\NV2FPT0WU
J-RT3-T3-5 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MorPTY5pcWKrdHnvckBw\iCqdX3hckBLNVKWMz3UN{02KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF05Njl4NUK5JO69VQ>? MX7TRW5ITVJ?
LP-1 cell MmXRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUPrVoxRUW6qaXLpeIlwdiCxZjDoeY1idiCOUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME23MlU1Pzh{IN88US=> MWnTRW5ITVJ?
K-562 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVTINHhkUW6qaXLpeIlwdiCxZjDoeY1idiCNLUW2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMECyOlU3KM7:TR?= M2fwRnNCVkeHUh?=
LS-123 cell NY\Ic|lDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mln1TY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMkOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVQxPjRizszN MmGxV2FPT0WU
K5 cell M{TvTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmnPTY5pcWKrdHnvckBw\iCqdX3hckBMPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zNkS4PUDPxE1? M3zMTXNCVkeHUh?=
LS-411N cell NIHUdHVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnzPTY5pcWKrdHnvckBw\iCqdX3hckBNWy12MUHOJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20PE41PzR6IN88US=> MVXTRW5ITVJ?
KG-1 cell NVLkfmYxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3PZ[WlvcGmkaYTpc44hd2ZiaIXtZY4hU0dvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;ND62NFg1PSEQvF2= M3;2[HNCVkeHUh?=
KINGS-1 cell M2HRSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEC0doZKdmirYnn0bY9vKG:oIHj1cYFvKEuLTlfTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTZ4Nk[g{txO NH;RVZRUSU6JRWK=
LXF-289 cell NIXDXIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFM6PTZizszN M4jxSXNCVkeHUh?=
MC116 cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXHRXXZPUW6qaXLpeIlwdiCxZjDoeY1idiCPQ{GxOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yOTRzIN88US=> MVrTRW5ITVJ?
KS-1 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVrCZXdEUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzPzNizszN M2nX[XNCVkeHUh?=
KU812 cell Mn\tS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4X4S2lvcGmkaYTpc44hd2ZiaIXtZY4hU1V6MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVE5QDNizszN MkSzV2FPT0WU
MEG-01 cell NFz5RY9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1GTy1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFAxODl6MEWg{txO NH3nfpRUSU6JRWK=
MFH-ino cell NV3meIltT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{j0OmlvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDd{NDFOwG0> M{PjUnNCVkeHUh?=
L-540 cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3vScWlvcGmkaYTpc44hd2ZiaIXtZY4hVC13NECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUG1MlA3PzFizszN NEXkdIRUSU6JRWK=
MHH-NB-11 cell MojUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1fjVGlvcGmkaYTpc44hd2ZiaIXtZY4hVUiKLV7CMVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01Oy5yOEG4JO69VQ>? MljYV2FPT0WU
MMAC-SF cell MlfBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH3TZodKdmirYnn0bY9vKG:oIHj1cYFvKE2PQVOtV2Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvPzl|MEeg{txO MXjTRW5ITVJ?
LB2241-RCC cell NETLNI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M32ze2lvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QS5yMkCxNkDPxE1? MUnTRW5ITVJ?
LB831-BLC cell M{H0dWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX\nVHZiUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMES2NFkh|ryP NGLJWW9USU6JRWK=
MOLT-16 cell NHqxUHlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnvOTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yPU43Ojl{IN88US=> M4HCS3NCVkeHUh?=
LC-1F cell NVfjRXA2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXnGeWpwUW6qaXLpeIlwdiCxZjDoeY1idiCOQz2xSkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlcvOzJ2NTFOwG0> MYPTRW5ITVJ?
MOLT-4 cell MnPrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofKTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK2MlY4PTNizszN MonlV2FPT0WU
MZ1-PC cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGfCdHpKdmirYnn0bY9vKG:oIHj1cYFvKE2cMT3QR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOzFzOTFOwG0> NIHQTpNUSU6JRWK=
MONO-MAC-6 cell M4XBUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnHQTY5pcWKrdHnvckBw\iCqdX3hckBOV06RLV3BR{03KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF05NjJ5ME[2JO69VQ>? M{DnbHNCVkeHUh?=
MZ2-MEL cell Mn7qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUnDSFR{UW6qaXLpeIlwdiCxZjDoeY1idiCPWkKtUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjJ6NUO3JO69VQ>? NFzQcFFUSU6JRWK=
MPP-89 cell M13YfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\uVXNXUW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODRyNEmg{txO NGLzNpdUSU6JRWK=
MZ7-mel cell M{Kzbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEHXS3ZKdmirYnn0bY9vKG:oIHj1cYFvKE2cNz3t[Ywh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPDd7MUGg{txO MoDqV2FPT0WU
LOXIMVI cell M4Loc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXvTY5pcWKrdHnvckBw\iCqdX3hckBNV1iLTW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlMyPTB|IN88US=> MmDEV2FPT0WU
NALM-6 cell NI\GXHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHPYRlhKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yQTJ7NTFOwG0> MYLTRW5ITVJ?
NB13 cell MorlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVjJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTF7LkS4O|ch|ryP NV6y[HVOW0GQR1XS
NB5 cell M1v5bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NILEWpdKdmirYnn0bY9vKG:oIHj1cYFvKE6ENTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MT6zPVgzPyEQvF2= MX3TRW5ITVJ?
NB17 cell MlvJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmTXTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1|Lk[zPFQ4KM7:TR?= NWLJe|NNW0GQR1XS
NCCIT cell M4LHcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3jpXWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOFSWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUKuPFY3OTZizszN NWGxbVF2W0GQR1XS
NB69 cell M2ji[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG5DPjliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUS0N|Yh|ryP MYnTRW5ITVJ?
NCI-H1304 cell NGL0bJZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlrlTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzNFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVI5NjF4Mkig{txO NIHhV5JUSU6JRWK=
NCI-H1395 cell NGq2OXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfqNo57UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{QTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTR{LkCxOlMh|ryP MmDQV2FPT0WU
MHH-PREB-1 cell MkHaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NULOb4xHUW6qaXLpeIlwdiCxZjDoeY1idiCPSFitVHJGSi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLke0OFY6KM7:TR?= Mn:2V2FPT0WU
MLMA cell NEHw[HJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7uPIlKdmirYnn0bY9vKG:oIHj1cYFvKE2OTVGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVQxOzJizszN NHHRT29USU6JRWK=
MN-60 cell NFrrbopIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGfmfnFKdmirYnn0bY9vKG:oIHj1cYFvKE2QLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xOU4yQTd7IN88US=> M2LFTXNCVkeHUh?=
MV-4-11 cell NGrobXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmXaTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20MlM3PDV2IN88US=> MlfPV2FPT0WU
NB6 cell Mnu0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2X5dmlvcGmkaYTpc44hd2ZiaIXtZY4hVkJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD17LkmyNlU6KM7:TR?= NWDBfoYzW0GQR1XS
NCI-H1355 cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYDhUpE3UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{PTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUGwNlgh|ryP NVHrcXFuW0GQR1XS

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
phospho-c-Abl(Tyr245) / phospho-c-Src(Tyr416) ; 

PubMed: 23049975     


Protein levels of phosphorylated c-Abl (Tyr245), c-Abl, phosphorylated c-Src (Tyr416), c-Src, and GAPDH in NSC-34 cells overexpressing human wild-type or mutant SOD1s treated with various concentrations of dasatinib were measured by western blot. Cells were cultured in serum-free culture medium with doxycycline (Dox, 2 µg/ml), and western blot was performed at 24 h after dasatinib addition.

p27 / p21; 

PubMed: 20145167     


Dasatnib induced cell cycle arrest. Dasatinib induced growth arrest, shown as a cell cycle distribution graph in the lower panel, correlated with increased p27 and p21 levels. Western blotting for levels of p27 and p21 was performed on protein lysates of THP-1 cells treated for 48 hours with indicated doses of dasatinib or DMSO. Detection of actin served as control for comparable protein loading.

cleaved caspase 3 ; 

PubMed: 20145167     


Dasatinib induced apoptosis. Dasatinib causes apoptosis in Mo7e-KitD816H cells as detected by cleavage of caspase 3. Whole cell lysates were prepared after 24 hour treatment with dasatinib. Caspase 3 and cleaved capase 3 were analyzed by western blotting. Actin serves as loading control.

p-FAK/p-STAT3; 

PubMed: 23721490     


The effect of dasatinib in cell signalling. Western blot analysis with phosphorylated Src, FAK, Stat3, Akt and MAPK in HCC cell lines after 24 hours treatment of dasatinib. The cell lines were arranged according to their IC50 to dasatinib. The top three were most sensitive, the bottom 3 were least sensitive.

23049975 20145167 23721490
Growth inhibition assay
Cell viability; 

PubMed: 23721490     


9 HCC cell lines were exposed to the dedicated concentrations of dasatinib for 72 hours, and IC50 was tested by MTS. Results represent the mean (± SD) of three experiments.

23721490
Immunofluorescence
SRC / Met; 

PubMed: 26517812     


Immunocytochemistry of SRC and Met localization. Cellular localization of SRC and Met following treatment for 48 h with dasatinib, crizotinib or combination in A. LN-18 and B. U373 cells. Scale bar denotes 10 μm. Nuclei were visualized by DAPI while SRC and Met were labeled with a fluorescein and Texas-red conjugated secondary antibodies, respectively.

α-tubulin; 

PubMed: 26517812     


Combination of dasatinib and crizotinib impedes the formation of the α-tubulin-labeled mitotic spindle. LN-18 cells were treated with dasatinib 0.2 μM, crizotinib 4 μM or their combination for 48 h. Mitotic spindle were visualized using α-tubulin antibody conjugated to a fluorescein-labeled secondary antibody. Nuclei were stained by DAPI. The scale bar denotes 10 μm.

F-actin / Actinin-4 / Paxillin; 

PubMed: 31053734     


Conditionally immortalized differentiated podocytes treated for one-hour with 2 µM kinase inhibitor were stained for F-actin (phalloidin), α-actinin-4, paxillin, and nuclei (Hoechst 33342) to assess cytoskeletal and focal adhesion architecture (scale bars = 50 µm). Podocytes treated with dasatinib showed a marked decrease in cell-to-cell contacts, cell size and number of focal adhesions.

26517812 31053734
ELISA
TNF-α; 

PubMed: 17684099     


U937 cells were differentiated with vitamin D3, pretreated with the indicated concentrations of drugs for 1 h and stimulated with LPS for 6 h. TNF-α secretion was measured by ELISA. The graph shows the mean of two experiments done in duplicate.

E-selectin; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of E-selectin was determined using ELISA (n = 3, ±SEM).

VCAM-1; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of VCAM-1 was determined using ELISA (n = 3, ±SEM).

17684099 31110200
In vivo Dasatinib reverses splenomegaly in LMP2A/MYC double transgenic mice. Dasatinib specifically prevents colony formation by LMP2A expressing bone marrow B cells and decreased spleen size in the TgE mice. Spleen mass is significantly decreased among Dasatinib treated Tg6/λ-MYC mice when compared to the control group. Dasatinib inhibits lymphadenopathy in LMP2A/MYC double transgenic mice. Dasatinib reverses splenomegaly in Rag1KO mice engrafted with tumor cells from LMP2A/MYC double transgenic mice. Dasatinib therapy inhibits Lyn phosphorylation in B lymphocyte tumors expressing LMP2A. [3]

Protocol

Kinase Assay:

[1]

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Kinase autophosphorylation assays:

Kinase assays using wild-type and mutant glutathione S-transferase (GST)-Abl fusion proteins (c-Abl amino acids 220-498) are done. GST-Abl fusion proteins are released from glutathione-Sepharose beads before use; the concentration of ATP is 5 μM. Immediately before use in kinase autophosphorylation and in vitro peptide substrate phosphorylation assays, GST-Abl kinase domain fusion proteins are treated with LAR tyrosine phosphatase. After 1-hour incubation at 30 °C, LAR phosphatase is inactivated by addition of sodium vanadate (1 mM). Immunoblot analysis comparing untreated GST-Abl kinase to dephosphorylated GST-Abl kinase is routinely done using phosphotyrosine-specific antibody 4G10 to confirm complete (>95%) dephosphorylation of tyrosine residues and c-Abl antibody CST 2862 to confirm equal loading of GST-Abl kinase. The Dasatinib concentration range is extended to 1,000 nM for mutant T315I. These same inhibitor concentrations are used for the in vitro peptide substrate phosphorylation assays. The three inhibitors are tested over these same concentration ranges against GST-Src kinase and GST-Lyn kinase.
Cell Research:

[1]

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  • Cell lines: Ba/F3 cell lines
  • Concentrations: ~32 nM
  • Incubation Time: 72 hours
  • Method:

    Ba/F3 cell lines are seeded in triplicate and incubated with escalating concentrations of Dasatinib for 72 hours. Proliferation is measured using a methanethiosulfonate-based viability assay. IC50 and IC90 values are reported as the mean of three independent experiments done in quadruplicate. The inhibitor concentration ranges are 0 nM to 32 nM (Dasatinib). The Dasatinib concentration range is extended to 200 nM for mutant T315I.


    (Only for Reference)
Animal Research:

[3]

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  • Animal Models: EμLMP2A (TgE and Tg6 strains), MYC (λ-MYC), and LMP2A/λ-MYC double transgenic mice (Tg6/λ-MYC)
  • Formulation: DMSO
  • Dosages: 30 mg/kg
  • Administration: Administered via i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 21 mg/mL warmed (41.5 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+dd H2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 506.02
Formula

C22H28ClN7O3S

CAS No. 863127-77-9
Storage powder
in solvent
Synonyms BMS-354825 Monohydrate

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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    C2
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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04063124 Not yet recruiting Drug: Dasatinib + Quercetin Alzheimer Disease The University of Texas Health Science Center at San Antonio|Mayo Clinic December 2019 Phase 1|Phase 2
NCT04115059 Not yet recruiting Drug: Dasatinib Waldenstrom Macroglobulinemia|DASATINIB Jorge J. Castillo MD|Bristol-Myers Squibb|Dana-Farber Cancer Institute November 2019 Phase 1
NCT03318770 Not yet recruiting Drug: Dasatinib and blinatumomab Acute Lymphoblastic Leukemia Gruppo Italiano Malattie EMatologiche dell''Adulto December 2018 --
NCT03625388 Recruiting Drug: Dasatinib Chronic Myelogenous Leukemia Hikma Pharmaceuticals LLC November 5 2018 Phase 2
NCT03193281 Recruiting Drug: Dasatinib|Drug: Imatinib Chronic Myeloid Leukemia University of Auckland New Zealand|Leukaemia & Blood Cancer New Zealand July 17 2017 Phase 2
NCT03041701 Recruiting Drug: Dasatinib|Drug: Ganitumab Rhabdomyosarcoma|Rhabdomyosarcoma- Alveolar|Rhabdomyosarcoma-Embryonal National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC) July 7 2017 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Frequently Asked Questions

  • Question 1:

    What’s the difference between S1021 and S7782?

  • Answer:

    Usually, hydrate will be more stable and dissolve better than free base. But this compound (S1021) dissolves better in DMSO than hydrate one (S7782).

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID