Dasatinib Monohydrate

For research use only.

Catalog No.S7782 Synonyms: BMS-354825 Monohydrate

92 publications

Dasatinib Monohydrate Chemical Structure

Molecular Weight(MW): 506.02

Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.

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Selleck's Dasatinib Monohydrate has been cited by 92 publications

Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
Targets
Abl [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
c-Kit (D816V) [2]
(Cell-free assay)
c-Kit (wt) [2]
(Cell-free assay)
0.6 nM 0.8 nM 37 nM 79 nM
In vitro

Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I. Dasatinib has a two-log (∼325-fold) increased potency relative to imatinib. Dasatinib potently inhibits wild-type Abl kinase and all mutants except T315I over a narrow range. Dasatinib directly targets wild-type and mutant Abl kinase domains and inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner. Dasatinib displays 325-fold greater potency compared with imatinib against cells expressing wild-type Bcr-Abl. [1] The percent of colonies of TgE bone marrow cells are decreased from 100% in untreated wells to 4.12% in Dasatinib treated wells. In the presence of Dasatinib, the difference in the percentage of colonies formed by WT and TgE bone marrow cells is statistically significant. Expression of LMP2A is able to promote B lymphocyte survival and proliferation, which can be inhibited by targeting Lyn and/or c-Abl kinases through Dasatinib. [3] Dasatinib treatment inhibits Src signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer cells. Treatment with increasing doses of Dasatinib (0.019 μM to 1.25 μM) for 3 days inhibits the growth of the C643, TPC1, BCPAP, and SW1736 cell lines by about 50% at low nanomolar concentrations, while higher concentrations are required to inhibit the growth of the K1 cell line. Treatment with 10 nM or 50 nM Dasatinib results in a 9-22% increase of cells in the G1 population among BCPAP and SW1736 and K1 cells, and a corresponding 7-18% decrease in the percentage of cells in the S phase. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K562 cell MY\Qdo9tcW[ncnH0bY9vKGG|c3H5 NY\HeFZ4PzJiaB?= NUXYN4NiSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjByMTFOwG0> NXnwWW9SOTV4MUW1NVI>
WiDr cell NGDWUXJRem:uaX\ldoF1cW:wIHHzd4F6 NFPtR|M4OiCq NYXYXGNGSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDXbWRzKGOnbHzzJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjB3MjFOwG0> MV2xOVYyPTVzMh?=
PC3 cell NFH5cllRem:uaX\ldoF1cW:wIHHzd4F6 NVv6VpN[PzJiaB?= NV:4ZnBYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODB7NDFOwG0> NGfBUXkyPTZzNUWxNi=>
MDA-MB-231 cell NVnyZ|c2WHKxbHnm[ZJifGmxbjDhd5NigQ>? NU\FSldNPzJiaB?= NUjab5o1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= M2TaOFE2PjF3NUGy
M07ep210 cell M3fMRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYm0PEBp NHj2SWJIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBOODencEKxNEBk\WyuczDh[pRmeiB2ODDodpMh[nliW{PIYZRpgW2rZHnu[UB2eHSja3WgZZN{[XluIFnDOVA:OC5yNzDuUS=> NUnhZ4prOTd7NU[wPFA>
K562 cell NWTJeYdWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XRSlQ5KGh? NGT4RW9Iem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBMPTZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBcO0ifdHj5cYllcW6nIIXweIFs\SCjc4PhfUwhUUN3ME2wMlAxOSEQvF2= MX:xO|k2PjB6MB?=
M07e cell MlTuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn\EOFghcA>? M4C1[2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG0xP2ViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHs{UF22aIntbYRqdmVidYD0ZYtmKGG|c3H5MEBKSzVyPUCuNFAyOiEQvF2= MnnINVc6PTZyOEC=
K562 cell NEC0b45EgXSxdH;4bYNqfHliYYPzZZk> MYW3NkBp MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDXV3QuQCC{ZXHn[Y51KGKjc3XkJG1VXCCjc4PhfUwhUUN3ME2xNk45OyEQvF2= NIHSTFYzOjJzN{i3Oy=>
U937 cell MojKR5l1d3SxeHnjbZR6KGG|c3H5 NWDtcW15PzJiaB?= NEG4XmFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBWQTN5IHPlcIx{KGGodHXyJFczKGi{czDifUBYW1RvODDy[YFo\W62IHLhd4VlKE2WVDDhd5NigSxiSVO1NF0yOy54MzFOwG0> M3rON|IzOjF5OEe3
K562 cell Mn\zVJJwdGmoZYLheIlwdiCjc4PhfS=> M1jicVczKGh? MkPlRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCNNU[yJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCFQ1u4JIF{e2G7LDDJR|UxRTBwNzDuUS=> NYfuU29POjN3MkGwNlA>
MDA-MB-435S cell NF:5SYlRem:uaX\ldoF1cW:wIHHzd4F6 NHPm[nQ4OiCq MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2GQT3NRk01OzWVIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9N{46KM7:TR?= NETvd|kzOzV{MUCyNC=>
NCI-H460 cell MV3Qdo9tcW[ncnH0bY9vKGG|c3H5 Mn25O|IhcA>? NVfXdHpVSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDR4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVgvQTlizszN NV;3NHoxOjN3MkGwNlA>
NCI-H23 cell MYXQdo9tcW[ncnH0bY9vKGG|c3H5 NEHtV5A4OiCq NGS0c|BCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JOjNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2yMlI4KM7:TR?= NXXzV|FMOjN3MkGwNlA>
A549 cell NWe5[W9LWHKxbHnm[ZJifGmxbjDhd5NigQ>? MofHO|IhcA>? MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF0yOi54NjFOwG0> MVGyN|UzOTB{MB?=
T47D cell NX7LeFZqWHKxbHnm[ZJifGmxbjDhd5NigQ>? NE[2PYw4OiCq MXPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFR2N1SgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjlizszN M2nuSVI{PTJzMEKw
HCT116 cell NG\yS4VRem:uaX\ldoF1cW:wIHHzd4F6 MXW3NkBp NVexcYNESW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2yMlMh|ryP M2DlN|I{PTJzMEKw
MCF7 cells NWixbnJ6WHKxbHnm[ZJifGmxbjDhd5NigQ>? MWe3NkBp MULBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF0zNjV5IN88US=> NU\Dcop5OjN3MkGwNlA>
RXF 393NL cell NFrSVFREgXSxdH;4bYNqfHliYYPzZZk> MnTjOEBl[Xm| MV3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDSXGYhOzl|TlygZ4VtdHNiYX\0[ZIhPCCmYYnzJIJ6KHC{b4Dp[Il2dSCrb3Tp[IUhe3SjaX7pcoctKEmFNUC9NlEvPyCwTR?= MUOyN|I2OzB5NB?=
PRXF DU145 cell Ml\PR5l1d3SxeHnjbZR6KGG|c3H5 M4\VdVQh\GG7cx?= M1HvXmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBTYEZiRGWxOFUh[2WubIOgZYZ1\XJiNDDkZZl{KGK7IIDyc5Bq\Gm3bTDpc4Rq\GVic4ThbY5qdmduIFnDOVA:OC5yNkKzJO69VQ>? NIK1dYQzOzJ3M{C3OC=>
LXFA 983L cell M3TlbGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnnHOEBl[Xm| M1rUdmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGxZTkFiOUizUEBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF02Pi53IH7N NYTKTnd1OjN{NUOwO|Q>
GXF251L cell MXTDfZRwfG:6aXPpeJkh[XO|YYm= MkDHOEBl[Xm| MoOxR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gS3hHOjVzTDDj[YxteyCjZoTldkA1KGSjeYOgZpkheHKxcHnkbZVuKGmxZHnk[UB{fGGrbnnu[{whUUN3ME2yMlI2KM7:TR?= M2nIO|I{OjV|MEe0
CXF 1103L cell MljFR5l1d3SxeHnjbZR6KGG|c3H5 NYLrTop4PCCmYYnz MkSyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR3hHKDFzMEPMJINmdGy|IHHmeIVzKDRiZHH5d{BjgSCycn;wbYRqfW1iaX;kbYRmKHO2YXnubY5oNCCLQ{WwQVQvOzZizszN MUKyN|I2OzB5NB?=
PAXF 1657L cell NXHvU|hsS3m2b4TvfIlkcXS7IHHzd4F6 MorPOEBl[Xm| MoHVR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGFZTiBzNkW3UEBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF0xNjF{MTFOwG0> M1ThWlI{OjV|MEe0
NCI-H1648 cell Mor4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M123TWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMkCxNUDPxE1? M3r0THNCVkeHUh?=
NCI-H1838 cell NYOyTpR5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUizPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzB5M{Og{txO MkfoV2FPT0WU
NCI-H2126 cell Mn7PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYLJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvQDd3NUKg{txO MnTUV2FPT0WU
NCI-H2141 cell M4X5[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEPPPJpKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE1OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lke3OVQh|ryP MlfWV2FPT0WU
NCI-H2107 cell M3rNZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\OSnhCUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyODdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mz60PFQ4KM7:TR?= NX;CTpN5W0GQR1XS
NCI-H747 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEK3eIpKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|Q4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yOEO2NkDPxE1? MnzNV2FPT0WU
NCI-H720 cell NVjTe5ZRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2K0W2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NlAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOC5{N{OzJO69VQ>? NYewPFBoW0GQR1XS
NKM-1 cell NUL2fXNZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWH0b|l2UW6qaXLpeIlwdiCxZjDoeY1idiCQS12tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4{ODh3OTFOwG0> M3PqPXNCVkeHUh?=
NMC-G1 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYG2fGlvUW6qaXLpeIlwdiCxZjDoeY1idiCQTVOtS|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTF4ME[g{txO MoK0V2FPT0WU
NTERA-S-cl-D1 cell MnqxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NED6[|JKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVIzQDNizszN NGX1bGZUSU6JRWK=
OCI-AML2 cell M3ewdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWTOWGJ2UW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:PS56NkG1OEDPxE1? MUfTRW5ITVJ?
OCUB-M cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnm1TY5pcWKrdHnvckBw\iCqdX3hckBQS1WELV2gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNFQ1OTJizszN MXPTRW5ITVJ?
OPM-2 cell NEjtZnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlvZTY5pcWKrdHnvckBw\iCqdX3hckBQWE1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;ND6yO|Y5PSEQvF2= M1O5SXNCVkeHUh?=
OS-RC-2 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV3pTVZHUW6qaXLpeIlwdiCxZjDoeY1idiCRUz3SR{0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB{MEOg{txO MmnUV2FPT0WU
ONS-76 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NILveopKdmirYnn0bY9vKG:oIHj1cYFvKE:QUz23OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE41Ojl3MTFOwG0> MlPIV2FPT0WU
OVCAR-4 cell M3H3[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWTJcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|c1OzNizszN MYTTRW5ITVJ?
NCI-H446 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3nZWmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi0OFYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPjJ5NjFOwG0> NHrhOolUSU6JRWK=
NCI-H510A cell M4\qZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4fHNWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NVBCKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yQS5|OUezJO69VQ>? M4qweXNCVkeHUh?=
PF-382 cell M1XSOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF;0RYxKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yPzZ5ODFOwG0> NEf2cmxUSU6JRWK=
NCI-H64 cell M4PGVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNkSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK5MlYzPTNizszN NVjHTmlTW0GQR1XS
PSN1 cell NXXM[IQ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWCwWpMxUW6qaXLpeIlwdiCxZjDoeY1idiCSU16xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1PDd2IN88US=> MV3TRW5ITVJ?
QIMR-WIL cell NYLFbFFHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI\EVY9KdmirYnn0bY9vKG:oIHj1cYFvKFGLTWKtW2lNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjdyNkK5JO69VQ>? NH:1R4hUSU6JRWK=
RL95-2 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYXKPXZ2UW6qaXLpeIlwdiCxZjDoeY1idiCUTEm1MVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTB|ODFOwG0> NFTid5BUSU6JRWK=
RCC10RGB cell M{DhdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXXieY1KUW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC52OUGxJO69VQ>? MmLVV2FPT0WU
RKO cell NYjXUo1pT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXzDZoh2UW6qaXLpeIlwdiCxZjDoeY1idiCUS1:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuOVI6PjZizszN NHjrdWdUSU6JRWK=
NCI-SNU-16 cell M13BeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\Fe2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLWPOWU0yPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QC53NkGyPEDPxE1? NWjWOoh7W0GQR1XS
RPMI-6666 cell MkW4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1HoTWlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF04NjJ5ME[3JO69VQ>? NUHSbmM4W0GQR1XS
NEC8 cell NILpWnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnLQTY5pcWKrdHnvckBw\iCqdX3hckBPTUN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12ND6zN|Yh|ryP NUDTSZd4W0GQR1XS
RS4-11 cell M2rCbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{TnPGlvcGmkaYTpc44hd2ZiaIXtZY4hWlN2LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME23MlY2Pzh5IN88US=> MXvTRW5ITVJ?
RXF393 cell NVfYO3loT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIrQS5dKdmirYnn0bY9vKG:oIHj1cYFvKFK[RkO5N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjN3NzFOwG0> NE\WcHFUSU6JRWK=
Raji cell MnznS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHzYNnlKdmirYnn0bY9vKG:oIHj1cYFvKFKjanmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGzMlc1QTdizszN NUW4cItrW0GQR1XS
NOS-1 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3;acmlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFA3OTJ7IN88US=> MUDTRW5ITVJ?
SBC-1 cell M{\zSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVP6NldXUW6qaXLpeIlwdiCxZjDoeY1idiCVQlOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU42Pzl6NDFOwG0> MYnTRW5ITVJ?
SF126 cell NXnDSVdCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmjBTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6zOVQyKM7:TR?= Mn\KV2FPT0WU
SF539 cell NV7sOIZOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHfERnJKdmirYnn0bY9vKG:oIHj1cYFvKFOINUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xN{45PTV5IN88US=> MnL6V2FPT0WU
SH-4 cell M1zE[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmPBTY5pcWKrdHnvckBw\iCqdX3hckBUUC12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG4OFE{KM7:TR?= NGe4cmNUSU6JRWK=
OMC-1 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHrxUHJKdmirYnn0bY9vKG:oIHj1cYFvKE:PQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yO{4yPDJ{IN88US=> MnTUV2FPT0WU
SIG-M5 cell NIHyNlZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXXJTIszUW6qaXLpeIlwdiCxZjDoeY1idiCVSVetUVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVkvODJ2OUOg{txO MUjTRW5ITVJ?
SJSA-1 cell NYfwOo9YT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIfFe3NKdmirYnn0bY9vKG:oIHj1cYFvKFOMU1GtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9PE44OjhyNTFOwG0> M2LQW3NCVkeHUh?=
SK-LMS-1 cell NHK1VXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVfJ[oZiUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3MUXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:Oy5zMUi4OkDPxE1? M1jvVHNCVkeHUh?=
SK-NEP-1 cell M{PIN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUTJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME24Mlg6OTV3IN88US=> MWTTRW5ITVJ?
SKM-1 cell M{Cwfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYHJcohq[mm2aX;uJI9nKGi3bXHuJHNMVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD17LkCxO|M1KM7:TR?= MlX0V2FPT0WU
SK-PN-DW cell M1n6Smdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3mxS2lvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVM3NjF7NEOg{txO NGDPRVNUSU6JRWK=
SK-UT-1 cell NWKzUWo5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4X4U2lvcGmkaYTpc44hd2ZiaIXtZY4hW0tvVWStNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9Nk4yPjZ7MzFOwG0> MlXHV2FPT0WU
SNB75 cell NIT4NIpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVf1T2lCUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDR|NTFOwG0> NHP5OopUSU6JRWK=
REH cell NVrJem5NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXfJcohq[mm2aX;uJI9nKGi3bXHuJHJGUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OjBwNkO1O{DPxE1? Mn34V2FPT0WU
SNU-C2B cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWPJcohq[mm2aX;uJI9nKGi3bXHuJHNPXS2FMlKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuN|A2QDlizszN NXztV3NPW0GQR1XS
RPMI-8866 cell NUKy[3hlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUDCO4pXUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg5PjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTF5LkS0OVUh|ryP MmDTV2FPT0WU
SW872 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEDIRWJKdmirYnn0bY9vKG:oIHj1cYFvKFOZOEeyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1OTZzIN88US=> Ml;uV2FPT0WU
SW962 cell MlTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWLJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTZ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkGxNlkzKM7:TR?= NUfZTohFW0GQR1XS
SF268 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkW1TY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xO|QxPCEQvF2= M{\5cHNCVkeHUh?=
TE-1 cell NWnWRYQ6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWnJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUC1OEDPxE1? MX7TRW5ITVJ?
8-MG-BA cell MoX0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGT3XHpKdmirYnn0bY9vKG:oIHj1cYFvKDhvTVetRmEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTV2NUig{txO M4TNVnNCVkeHUh?=
A101D cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWHFZ3dEUW6qaXLpeIlwdiCxZjDoeY1idiCDMUCxSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4xOzB2MzFOwG0> M{LOdnNCVkeHUh?=
A253 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXvJcohq[mm2aX;uJI9nKGi3bXHuJGEzPTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTNwN{OyOFYh|ryP NXnnPJhFW0GQR1XS
A3-KAW cell MlKxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{Lve2lvcGmkaYTpc44hd2ZiaIXtZY4hSTNvS1HXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlk5PDV{IN88US=> M{P0T3NCVkeHUh?=
A4-Fuk cell NXnBOpZpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXfFe29mUW6qaXLpeIlwdiCxZjDoeY1idiCDND3GeYsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVM5NjFyMEmg{txO M4HSO3NCVkeHUh?=
A388 cell NWfmcmhFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHzieYJKdmirYnn0bY9vKG:oIHj1cYFvKEF|OEigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFUxQTVizszN M2PTVHNCVkeHUh?=
ACN cell NFviOZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlvXTY5pcWKrdHnvckBw\iCqdX3hckBCS05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwOEKyOVIh|ryP M4nLUXNCVkeHUh?=
A704 cell M2X2[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2XKV2lvcGmkaYTpc44hd2ZiaIXtZY4hSTdyNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVQ6OSEQvF2= MlTJV2FPT0WU
ALL-PO cell NUX6SHFDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWn4bHQ1UW6qaXLpeIlwdiCxZjDoeY1idiCDTFytVG8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVExNjd7M{ig{txO MmK1V2FPT0WU
ARH-77 cell MlW0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVfJcohq[mm2aX;uJI9nKGi3bXHuJGFTUC15NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Mz60OlkyPSEQvF2= NVW5RXRsW0GQR1XS
SR cell M2rDZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlzYTY5pcWKrdHnvckBw\iCqdX3hckBUWiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:PC52OUm1OEDPxE1? NG\a[JNUSU6JRWK=
BB65-RCC cell MlHKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJGJDPjVvUlPDJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA5OjJ5IN88US=> MmjzV2FPT0WU
BB49-HNC cell Mn\vS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{LG[WlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ2OT3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOzh3OUmg{txO MVXTRW5ITVJ?
BC-1 cell NGHLemFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUSxeJBxUW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yPE43PTFizszN NIDEXY1USU6JRWK=
BC-3 cell NWTQUGVXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnnITY5pcWKrdHnvckBw\iCqdX3hckBDSy1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMj6xNVM5KM7:TR?= NEHxTlJUSU6JRWK=
BL-41 cell NE\TeYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVfJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTRzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkK5NVI{KM7:TR?= MlrnV2FPT0WU
BL-70 cell MlXES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUXwSolVUW6qaXLpeIlwdiCxZjDoeY1idiCETD23NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMEC4NlE5KM7:TR?= M3jLZ3NCVkeHUh?=
SW684 cell NIPrVIpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlX3TY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6zOFk5KM7:TR?= NYDKc5Z4W0GQR1XS
BOKU cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYHJcohq[mm2aX;uJI9nKGi3bXHuJGJQU1ViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwNEmxN|Mh|ryP MmLMV2FPT0WU
SW954 cell NGG1cIFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2rmeGlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFI6OjdizszN MonoV2FPT0WU
C2BBe1 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlK0TY5pcWKrdHnvckBw\iCqdX3hckBEOkKEZUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFg{ODhizszN MUTTRW5ITVJ?
BV-173 cell NWGwbGVxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4HVR2lvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxODByMEGwPUDPxE1? NUHhOFBqW0GQR1XS
Becker cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3zyR2lvcGmkaYTpc44hd2ZiaIXtZY4hSmWla3XyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{ODB|IN88US=> MnnqV2FPT0WU
SW982 cell M1jINmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCxNVE2KM7:TR?= MoXtV2FPT0WU
697 cell MmqwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3PWTWlvcGmkaYTpc44hd2ZiaIXtZY4hPjl5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG5PVg4KM7:TR?= MU\TRW5ITVJ?
TE-15 cell NXjTeVJJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEPpfIFKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUG1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxPTh7MTFOwG0> MYfTRW5ITVJ?
TE-11 cell MkfPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1XSPWlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFc5PThizszN M2n4b3NCVkeHUh?=
TE-5 cell M37uTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLjPZZKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuO|kyOzlizszN NWP0fGpkW0GQR1XS
TE-6 cell NILIUlBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwMkGyNlYh|ryP M3X6NXNCVkeHUh?=
TE-9 cell NUXQZXlnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mm[yTY5pcWKrdHnvckBw\iCqdX3hckBVTS17IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLki3OVMzKM7:TR?= NV;sWZE1W0GQR1XS
TGBC24TKB cell NIXDUWhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmTFTY5pcWKrdHnvckBw\iCqdX3hckBVT0KFMkTUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODR5NkGg{txO M1j1TXNCVkeHUh?=
TGW cell MmDpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mkf0TY5pcWKrdHnvckBw\iCqdX3hckBVT1diY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFzLkK4Nlgh|ryP NVniWm5{W0GQR1XS
TK10 cell MmDDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{PjbmlvcGmkaYTpc44hd2ZiaIXtZY4hXEtzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVE4PCEQvF2= MYjTRW5ITVJ?
TGBC1TKB cell MnO0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1PUd2lvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{HUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODZzNkSg{txO MlTFV2FPT0WU
A498 cell NUm1N|BWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnvxTY5pcWKrdHnvckBw\iCqdX3hckBCPDl6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkC3Nlg1KM7:TR?= NVHHOnM5W0GQR1XS
UACC-257 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1zUUGlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVEzNjlzOUig{txO NHe1U|BUSU6JRWK=
U-87-MG cell NFPKRoNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DTRWlvcGmkaYTpc44hd2ZiaIXtZY4hXS16Nz3NS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|AvPzZ4IN88US=> NFrib5RUSU6JRWK=
BB30-HNC cell MkfuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlPsTY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPTR|NzFOwG0> MnOzV2FPT0WU
no-10 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3nVOmlvcGmkaYTpc44hd2ZiaIXtZY4hdm9vMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|E6OzFizszN MYTTRW5ITVJ?
CAS-1 cell M3X3NWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF7Zd4JKdmirYnn0bY9vKG:oIHj1cYFvKEODUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlQxQTl{IN88US=> NV\u[GJFW0GQR1XS
CGTH-W-1 cell NEPCTnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NI\xT|ZKdmirYnn0bY9vKG:oIHj1cYFvKEOJVFitW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB|NUS4JO69VQ>? M3\yUnNCVkeHUh?=
TE-10 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWLpU2J1UW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPjN3NzFOwG0> NFTYPI1USU6JRWK=
COLO-684 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkXqTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLU[4OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OFYvOjJ3ODFOwG0> MUfTRW5ITVJ?
TE-12 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mme2TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVg3OSEQvF2= Mn7CV2FPT0WU
COR-L279 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH:wbWNKdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01OC5{OEWyJO69VQ>? M3vZZnNCVkeHUh?=
TE-8 cell NX\ETlNST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUfJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEG1O|Yh|ryP NX62Xo1wW0GQR1XS
CP66-MEL cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVTJcohq[mm2aX;uJI9nKGi3bXHuJGNRPjZvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE6PTNzIN88US=> NXfKbZZvW0GQR1XS
CTV-1 cell M{jIO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVnJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwNFA1ODN4IN88US=> MX;TRW5ITVJ?
VA-ES-BJ cell M3vWUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{QTB{IN88US=> M2j6SnNCVkeHUh?=
D-263MG cell MnzUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmXwTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ4M13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlM3OjJ2IN88US=> MYXTRW5ITVJ?
D-336MG cell M1nycWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmjvTY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxPjJ7ODFOwG0> MVjTRW5ITVJ?
D-502MG cell M1nRcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnvDTY5pcWKrdHnvckBw\iCqdX3hckBFNTVyMl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xMlI{Ozd4IN88US=> NFGwe5VUSU6JRWK=
DJM-1 cell NITLelFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFWz[XpKdmirYnn0bY9vKG:oIHj1cYFvKESMTT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME22MlQ5PTV6IN88US=> NF3VXHBUSU6JRWK=
no-11 cell NHfhRnpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEHaOW5KdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlUxOjJ6IN88US=> MkK1V2FPT0WU
DMS-153 cell M{O4Tmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LPfGlvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUG1N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVQvODB{ODFOwG0> NVS2fIJHW0GQR1XS
DSH1 cell NXfnOXlIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MofPTY5pcWKrdHnvckBw\iCqdX3hckBFW0hzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkK0NFAyKM7:TR?= M3rrR3NCVkeHUh?=
DU-4475 cell NIPz[3BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWTJcohq[mm2aX;uJI9nKGi3bXHuJGRWNTR2N{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUiuNlE3PTJizszN NV;WTI5tW0GQR1XS
EB-3 cell NFLuNlNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYfaRXNUUW6qaXLpeIlwdiCxZjDoeY1idiCHQj2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zOE4{OTF6IN88US=> MWTTRW5ITVJ?
EHEB cell NWXwXIdRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml7LTY5pcWKrdHnvckBw\iCqdX3hckBGUEWEIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMD6wOlU3KM7:TR?= NXm3NGlrW0GQR1XS
COLO-829 cell M2KyWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVTHTmRrUW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVgzQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zMkKxN{DPxE1? NXHRRmNVW0GQR1XS
CP67-MEL cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVLJcohq[mm2aX;uJI9nKGi3bXHuJGNRPjdvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlIxPDh6IN88US=> M2PTVHNCVkeHUh?=
ES8 cell MmPtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVnzW5p{UW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOyMlEzPTJizszN NEHyXWdUSU6JRWK=
EVSA-T cell MmfSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUnJcohq[mm2aX;uJI9nKGi3bXHuJGVXW0FvVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;OT6yO|c6OyEQvF2= NYjrOHZiW0GQR1XS
ES4 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGVUPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OS5yNUG0OUDPxE1? M1u3[XNCVkeHUh?=
ETK-1 cell M4PZVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFq5SpdKdmirYnn0bY9vKG:oIHj1cYFvKEWWSz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzQDN{IN88US=> NULMRXQzW0GQR1XS
ES6 cell MmfrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlHqTY5pcWKrdHnvckBw\iCqdX3hckBGWzZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEOxPVMh|ryP NVXsUXE{W0GQR1XS
EW-24 cell NEDEfpVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1rCPWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMkSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuO|gyPjVizszN NULkbG14W0GQR1XS
EoL-1-cell cell NFXlcI9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MojOTY5pcWKrdHnvckBw\iCqdX3hckBGd0xvMT3j[YxtKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjByMECxN|A6KM7:TR?= M37UdXNCVkeHUh?=
Calu-6 cell NVrxUWRVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV7ES5p5UW6qaXLpeIlwdiCxZjDoeY1idiCFYXz1MVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVMvODV5NEGg{txO MU\TRW5ITVJ?
GAK cell NGTRb4lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIr0VZdKdmirYnn0bY9vKG:oIHj1cYFvKEeDSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;M{GuNlY5PiEQvF2= M4rJVnNCVkeHUh?=
D-247MG cell NEfZOJdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUXaXm9DUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK0O21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF03NjF{NUG5JO69VQ>? MkXVV2FPT0WU
GB-1 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIfB[IxKdmirYnn0bY9vKG:oIHj1cYFvKEeELUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFIyPTdizszN MX3TRW5ITVJ?
GI-ME-N cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGdKNU2HLV6gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFYyOThizszN MVrTRW5ITVJ?
GCIY cell NU[2bYRUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1vPdWlvcGmkaYTpc44hd2ZiaIXtZY4hT0OLWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wPVY2PiEQvF2= MYLTRW5ITVJ?
GT3TKB cell MmnES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV7tfZpnUW6qaXLpeIlwdiCxZjDoeY1idiCJVEPUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVkvOzV3NE[g{txO M{nJU3NCVkeHUh?=
HC-1 cell MnXYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGDFbVFKdmirYnn0bY9vKG:oIHj1cYFvKEiFLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK0MlU2PTFizszN M1HLU3NCVkeHUh?=
HAL-01 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHLxOm1KdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVkvPzV2MzFOwG0> MoDXV2FPT0WU
HCC1187 cell NX3VVWJyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2Tw[2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMUG4O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|UvQDB3MjFOwG0> NIL1RZRUSU6JRWK=
DEL cell Ml[5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoPVTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTRzLkmwPFYh|ryP NYfuZWlpW0GQR1XS
HCC1599 cell NWDLWY13T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3zkSGlvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMUW5PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|IvOzN{NTFOwG0> NV;i[Xg1W0GQR1XS
DOHH-2 cell MmrmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M17IbGlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyPzF7IN88US=> MVXTRW5ITVJ?
HCC2157 cell NIrl[YJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MofPTY5pcWKrdHnvckBw\iCqdX3hckBJS0N{MUW3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zO{46QTR4IN88US=> MWjTRW5ITVJ?
HCE-4 cell M37mSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUHJcohq[mm2aX;uJI9nKGi3bXHuJGhETS12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkK2OFM6KM7:TR?= NHvYfGpUSU6JRWK=
HCE-T cell MlqyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYGweWl1UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1WtWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU42PjdzNDFOwG0> NHPmOoRUSU6JRWK=
HEL cell MmfwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2jqXmlvcGmkaYTpc44hd2ZiaIXtZY4hUEWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMD60O|c3KM7:TR?= MYjTRW5ITVJ?
EM-2 cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NETkWJRKdmirYnn0bY9vKG:oIHj1cYFvKEWPLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFAxODBzMEe4JO69VQ>? NFy4OIxUSU6JRWK=
HT-144 cell NGm1SFRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWXJdXVPUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPTN4MEmg{txO MWPTRW5ITVJ?
EW-16 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYj1dHVoUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE44PjF5ODFOwG0> MnHZV2FPT0WU
IA-LM cell MkntS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVq3NoR1UW6qaXLpeIlwdiCxZjDoeY1idiCLQT3MUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVIvPDR2NTFOwG0> MnzrV2FPT0WU
IST-MEL1 cell NG\2SG1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVfWW21PUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5zM{S1JO69VQ>? NFOxeYdUSU6JRWK=
IST-MES1 cell M13GNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV64W2pxUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yOEW1NkDPxE1? NGrEO4pUSU6JRWK=
GI-1 cell MmTPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI[2[YhKdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuN|YzOiEQvF2= NGfqcmVUSU6JRWK=
IST-SL2 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWe1UI86UW6qaXLpeIlwdiCxZjDoeY1idiCLU2StV2wzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjVyM{CyJO69VQ>? MnH5V2FPT0WU
JVM-2 cell NHnDOGRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUXJcohq[mm2aX;uJI9nKGi3bXHuJGpXVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1{LkO2Nlg1KM7:TR?= MVPTRW5ITVJ?
JVM-3 cell MmnJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2ToSmlvcGmkaYTpc44hd2ZiaIXtZY4hUl[PLUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUO3MlI{OzhizszN Mm[0V2FPT0WU
KALS-1 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFnFe4RKdmirYnn0bY9vKG:oIHj1cYFvKEuDTGOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xQTR7IN88US=> NE\2S|BUSU6JRWK=
KARPAS-422 cell NX21ZnpNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVLJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20NlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOzN7OUeg{txO NXvzfFZwW0GQR1XS
JiyoyeP-2003 cell M2fHbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFvTSG1KdmirYnn0bY9vKG:oIHj1cYFvKEqreX;5[XAuOjByMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MT63N|Q3PiEQvF2= MVrTRW5ITVJ?
KARPAS-45 cell NV3DN3lYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVqyXXpoUW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTdwNUG2O|Eh|ryP NVjBcWdqW0GQR1XS
KGN cell Ml;jS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml2wTY5pcWKrdHnvckBw\iCqdX3hckBMT05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEG5OFIh|ryP MYLTRW5ITVJ?
KLE cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGHzU25KdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNVMyPyEQvF2= NWn3cZJYW0GQR1XS
KNS-42 cell NYTJ[|VsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnvuTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNlQ1OTJizszN MkLwV2FPT0WU
KNS-81-FD cell M4X6WWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH[5d2pKdmirYnn0bY9vKG:oIHj1cYFvKEuQUz24NU1HTCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OjNwMUS2JO69VQ>? NHrUcnZUSU6JRWK=
KP-N-YS cell MnLPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmjXTY5pcWKrdHnvckBw\iCqdX3hckBMWC2QLWnTJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNk46Ojh|IN88US=> Mof1V2FPT0WU
HOP-62 cell M{jxNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUTJcohq[mm2aX;uJI9nKGi3bXHuJGhQWC14MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNVg{PCEQvF2= M3SxdHNCVkeHUh?=
KURAMOCHI cell M4i0e2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUXJcohq[mm2aX;uJI9nKGi3bXHuJGtWWkGPT1PITUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOzR6NzFOwG0> MWXTRW5ITVJ?
HUTU-80 cell MorTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{TTWmlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4{OTR{IN88US=> NETKNIpUSU6JRWK=
LAMA-84 cell NXnXSIxkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1nlbWlvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMEOyNFch|ryP NGHTSYRUSU6JRWK=
LB1047-RCC cell Mo\HS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3ziV2lvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yMEm4PFch|ryP NHzGSFhUSU6JRWK=
LB2518-MEL cell NHO3cZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGxDOjVzOD3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTRzNkKg{txO MXXTRW5ITVJ?
LB373-MEL-D cell M1f6WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXrJcohq[mm2aX;uJI9nKGi3bXHuJGxDOzd|LV3FUE1FKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjh{NUC4JO69VQ>? NHjQXnVUSU6JRWK=
LB771-HNC cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmLSTY5pcWKrdHnvckBw\iCqdX3hckBNSjd5MT3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVIvPTd3NUGg{txO MlrBV2FPT0WU
LB996-RCC cell NXHLPHZPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUixRpp{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEC5PVEzKM7:TR?= Mly2V2FPT0WU
LC-2-ad cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYHJcohq[mm2aX;uJI9nKGi3bXHuJGxENTJvYXSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFI2QDZizszN MXXTRW5ITVJ?
J-RT3-T3-5 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVrJcohq[mm2aX;uJI9nKGi3bXHuJGouWlR|LWSzMVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvQTZ3Mkmg{txO MXHTRW5ITVJ?
LP-1 cell NHjJOlFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmDnTY5pcWKrdHnvckBw\iCqdX3hckBNWC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD15LkW0O|gzKM7:TR?= MlLVV2FPT0WU
K-562 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVH4ZlZRUW6qaXLpeIlwdiCxZjDoeY1idiCNLUW2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMECyOlU3KM7:TR?= NWXQcpNuW0GQR1XS
LS-123 cell NHnXU3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVTldpgyUW6qaXLpeIlwdiCxZjDoeY1idiCOUz2xNlMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTRyNkSg{txO NHPOU5FUSU6JRWK=
K5 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWnienhnUW6qaXLpeIlwdiCxZjDoeY1idiCNNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xOlQ5QSEQvF2= NELKOXlUSU6JRWK=
LS-411N cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2TOV2lvcGmkaYTpc44hd2ZiaIXtZY4hVFNvNEGxUkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OFgvPDd2ODFOwG0> MX3TRW5ITVJ?
KG-1 cell M3znUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGDYUFhKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUSuOlA5PDVizszN NUm5NGF{W0GQR1XS
KINGS-1 cell M4\uNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2n3fmlvcGmkaYTpc44hd2ZiaIXtZY4hU0mQR2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yPjZ4NjFOwG0> M33BbnNCVkeHUh?=
LXF-289 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEfGbVlKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODN7NU[g{txO MVXTRW5ITVJ?
MC116 cell M4O0b2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXnafVNnUW6qaXLpeIlwdiCxZjDoeY1idiCPQ{GxOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yOTRzIN88US=> NHzOVHdUSU6JRWK=
KS-1 cell Mk\LS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoDnTY5pcWKrdHnvckBw\iCqdX3hckBMWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCyO|Mh|ryP NECyVWNUSU6JRWK=
KU812 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYLJcohq[mm2aX;uJI9nKGi3bXHuJGtWQDF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkGxPFg{KM7:TR?= MV7TRW5ITVJ?
MEG-01 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHWzSJhKdmirYnn0bY9vKG:oIHj1cYFvKE2HRz2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xODByMEm4NFUh|ryP NVzuVmlNW0GQR1XS
MFH-ino cell MofoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJG1HUC2rbn:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFQ4OjRizszN NX\Z[JNWW0GQR1XS
L-540 cell NYCwPZlKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHH0OIxKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xOU4xPjdzIN88US=> M4W2VHNCVkeHUh?=
MHH-NB-11 cell MoDqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUjJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OFMvODhzODFOwG0> NUTLZ|VEW0GQR1XS
MMAC-SF cell NWqxPFRuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGjobpNKdmirYnn0bY9vKG:oIHj1cYFvKE2PQVOtV2Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvPzl|MEeg{txO MULTRW5ITVJ?
LB2241-RCC cell MnryS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYXXXIJVUW6qaXLpeIlwdiCxZjDoeY1idiCOQkKyOFEuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD17LkCyNFEzKM7:TR?= MV7TRW5ITVJ?
LB831-BLC cell NF\GZZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NITUbFZKdmirYnn0bY9vKG:oIHj1cYFvKEyEOEOxMWJNSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yNE[wPUDPxE1? NVzZXplOW0GQR1XS
MOLT-16 cell NVPk[Wk{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWn4PZdWUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0zQS54MkmyJO69VQ>? NHPCSodUSU6JRWK=
LC-1F cell M17XS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Moq0TY5pcWKrdHnvckBw\iCqdX3hckBNSy1zRjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MkeuN|I1PSEQvF2= NEHBeGdUSU6JRWK=
MOLT-4 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVTJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Mk[uOlc2OyEQvF2= M{KzN3NCVkeHUh?=
MZ1-PC cell NWTm[2ZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWLvXotyUW6qaXLpeIlwdiCxZjDoeY1idiCPWkGtVGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODNzMUmg{txO NFXpNG9USU6JRWK=
MONO-MAC-6 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm[1TY5pcWKrdHnvckBw\iCqdX3hckBOV06RLV3BR{03KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF05NjJ5ME[2JO69VQ>? NXvNcpJZW0GQR1XS
MZ2-MEL cell MoW4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV;yUHl2UW6qaXLpeIlwdiCxZjDoeY1idiCPWkKtUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjJ6NUO3JO69VQ>? NWL4WY1XW0GQR1XS
MPP-89 cell NXT5Z49MT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVrJcohq[mm2aX;uJI9nKGi3bXHuJG1RWC16OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wOFA1QSEQvF2= MWfTRW5ITVJ?
MZ7-mel cell NHLHTJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG1bPy2vZXygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuOFc6OTFizszN NWrjNpZJW0GQR1XS
LOXIMVI cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVvq[3J1UW6qaXLpeIlwdiCxZjDoeY1idiCOT2jJUXZKKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjNzNUCzJO69VQ>? M4DFSXNCVkeHUh?=
NALM-6 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI\kTIxKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yQTJ7NTFOwG0> M2\ObXNCVkeHUh?=
NB13 cell NWnrUWdIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHnR[YtKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUG5MlQ5PzdizszN NIDRV2lUSU6JRWK=
NB5 cell NE\rbHNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml\QTY5pcWKrdHnvckBw\iCqdX3hckBPSjViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwM{m4Nlch|ryP NYjLXndrW0GQR1XS
NB17 cell MlHRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MULJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTNwNkO4OFch|ryP M4C3RnNCVkeHUh?=
NCCIT cell MkPCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGq1R2VKdmirYnn0bY9vKG:oIHj1cYFvKE6FQ1nUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yMlg3PjF4IN88US=> NGT1SmlUSU6JRWK=
NB69 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDKdnFZUW6qaXLpeIlwdiCxZjDoeY1idiCQQk[5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE1PDN4IN88US=> MV;TRW5ITVJ?
NCI-H1304 cell NIL2XnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlgvOTZ{ODFOwG0> MWTTRW5ITVJ?
NCI-H1395 cell NULMXY5ET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnTWTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVQzNjBzNkOg{txO NEPQTnBUSU6JRWK=
MHH-PREB-1 cell NHfhVJRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHi4d2VKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3QVmVDNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwN{S0Olkh|ryP Mk[2V2FPT0WU
MLMA cell NYLEPZhKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDQSWVTUW6qaXLpeIlwdiCxZjDoeY1idiCPTF3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE1ODN{IN88US=> NETlTYlUSU6JRWK=
MN-60 cell NHfqN|dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIjVO5FKdmirYnn0bY9vKG:oIHj1cYFvKE2QLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xOU4yQTd7IN88US=> NUjET5ZQW0GQR1XS
MV-4-11 cell NEOy[FRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3TmWGlvcGmkaYTpc44hd2ZiaIXtZY4hVVZvND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9OE4{PjR3NDFOwG0> Mn3EV2FPT0WU
NB6 cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWfVV2hNUW6qaXLpeIlwdiCxZjDoeY1idiCQQk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUmuPVIzPTlizszN MkXhV2FPT0WU
NCI-H1355 cell NX3uXFc5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3WwPGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjFzMEK4JO69VQ>? NGmy[WRUSU6JRWK=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
phospho-c-Abl(Tyr245) / phospho-c-Src(Tyr416) ; 

PubMed: 23049975     


Protein levels of phosphorylated c-Abl (Tyr245), c-Abl, phosphorylated c-Src (Tyr416), c-Src, and GAPDH in NSC-34 cells overexpressing human wild-type or mutant SOD1s treated with various concentrations of dasatinib were measured by western blot. Cells were cultured in serum-free culture medium with doxycycline (Dox, 2 µg/ml), and western blot was performed at 24 h after dasatinib addition.

p27 / p21; 

PubMed: 20145167     


Dasatnib induced cell cycle arrest. Dasatinib induced growth arrest, shown as a cell cycle distribution graph in the lower panel, correlated with increased p27 and p21 levels. Western blotting for levels of p27 and p21 was performed on protein lysates of THP-1 cells treated for 48 hours with indicated doses of dasatinib or DMSO. Detection of actin served as control for comparable protein loading.

cleaved caspase 3 ; 

PubMed: 20145167     


Dasatinib induced apoptosis. Dasatinib causes apoptosis in Mo7e-KitD816H cells as detected by cleavage of caspase 3. Whole cell lysates were prepared after 24 hour treatment with dasatinib. Caspase 3 and cleaved capase 3 were analyzed by western blotting. Actin serves as loading control.

p-FAK/p-STAT3; 

PubMed: 23721490     


The effect of dasatinib in cell signalling. Western blot analysis with phosphorylated Src, FAK, Stat3, Akt and MAPK in HCC cell lines after 24 hours treatment of dasatinib. The cell lines were arranged according to their IC50 to dasatinib. The top three were most sensitive, the bottom 3 were least sensitive.

23049975 20145167 23721490
Growth inhibition assay
Cell viability; 

PubMed: 23721490     


9 HCC cell lines were exposed to the dedicated concentrations of dasatinib for 72 hours, and IC50 was tested by MTS. Results represent the mean (± SD) of three experiments.

23721490
Immunofluorescence
SRC / Met; 

PubMed: 26517812     


Immunocytochemistry of SRC and Met localization. Cellular localization of SRC and Met following treatment for 48 h with dasatinib, crizotinib or combination in A. LN-18 and B. U373 cells. Scale bar denotes 10 μm. Nuclei were visualized by DAPI while SRC and Met were labeled with a fluorescein and Texas-red conjugated secondary antibodies, respectively.

α-tubulin; 

PubMed: 26517812     


Combination of dasatinib and crizotinib impedes the formation of the α-tubulin-labeled mitotic spindle. LN-18 cells were treated with dasatinib 0.2 μM, crizotinib 4 μM or their combination for 48 h. Mitotic spindle were visualized using α-tubulin antibody conjugated to a fluorescein-labeled secondary antibody. Nuclei were stained by DAPI. The scale bar denotes 10 μm.

F-actin / Actinin-4 / Paxillin; 

PubMed: 31053734     


Conditionally immortalized differentiated podocytes treated for one-hour with 2 µM kinase inhibitor were stained for F-actin (phalloidin), α-actinin-4, paxillin, and nuclei (Hoechst 33342) to assess cytoskeletal and focal adhesion architecture (scale bars = 50 µm). Podocytes treated with dasatinib showed a marked decrease in cell-to-cell contacts, cell size and number of focal adhesions.

26517812 31053734
ELISA
TNF-α; 

PubMed: 17684099     


U937 cells were differentiated with vitamin D3, pretreated with the indicated concentrations of drugs for 1 h and stimulated with LPS for 6 h. TNF-α secretion was measured by ELISA. The graph shows the mean of two experiments done in duplicate.

E-selectin; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of E-selectin was determined using ELISA (n = 3, ±SEM).

VCAM-1; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of VCAM-1 was determined using ELISA (n = 3, ±SEM).

17684099 31110200
In vivo Dasatinib reverses splenomegaly in LMP2A/MYC double transgenic mice. Dasatinib specifically prevents colony formation by LMP2A expressing bone marrow B cells and decreased spleen size in the TgE mice. Spleen mass is significantly decreased among Dasatinib treated Tg6/λ-MYC mice when compared to the control group. Dasatinib inhibits lymphadenopathy in LMP2A/MYC double transgenic mice. Dasatinib reverses splenomegaly in Rag1KO mice engrafted with tumor cells from LMP2A/MYC double transgenic mice. Dasatinib therapy inhibits Lyn phosphorylation in B lymphocyte tumors expressing LMP2A. [3]

Protocol

Kinase Assay:

[1]

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Kinase autophosphorylation assays:

Kinase assays using wild-type and mutant glutathione S-transferase (GST)-Abl fusion proteins (c-Abl amino acids 220-498) are done. GST-Abl fusion proteins are released from glutathione-Sepharose beads before use; the concentration of ATP is 5 μM. Immediately before use in kinase autophosphorylation and in vitro peptide substrate phosphorylation assays, GST-Abl kinase domain fusion proteins are treated with LAR tyrosine phosphatase. After 1-hour incubation at 30 °C, LAR phosphatase is inactivated by addition of sodium vanadate (1 mM). Immunoblot analysis comparing untreated GST-Abl kinase to dephosphorylated GST-Abl kinase is routinely done using phosphotyrosine-specific antibody 4G10 to confirm complete (>95%) dephosphorylation of tyrosine residues and c-Abl antibody CST 2862 to confirm equal loading of GST-Abl kinase. The Dasatinib concentration range is extended to 1,000 nM for mutant T315I. These same inhibitor concentrations are used for the in vitro peptide substrate phosphorylation assays. The three inhibitors are tested over these same concentration ranges against GST-Src kinase and GST-Lyn kinase.
Cell Research:

[1]

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  • Cell lines: Ba/F3 cell lines
  • Concentrations: ~32 nM
  • Incubation Time: 72 hours
  • Method:

    Ba/F3 cell lines are seeded in triplicate and incubated with escalating concentrations of Dasatinib for 72 hours. Proliferation is measured using a methanethiosulfonate-based viability assay. IC50 and IC90 values are reported as the mean of three independent experiments done in quadruplicate. The inhibitor concentration ranges are 0 nM to 32 nM (Dasatinib). The Dasatinib concentration range is extended to 200 nM for mutant T315I.


    (Only for Reference)
Animal Research:

[3]

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  • Animal Models: EμLMP2A (TgE and Tg6 strains), MYC (λ-MYC), and LMP2A/λ-MYC double transgenic mice (Tg6/λ-MYC)
  • Dosages: 30 mg/kg
  • Administration: Administered via i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 21 mg/mL warmed (41.5 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+dd H2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 506.02
Formula

C22H28ClN7O3S

CAS No. 863127-77-9
Storage powder
in solvent
Synonyms BMS-354825 Monohydrate
Smiles O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04063124 Suspended Drug: Dasatinib + Quercetin Alzheimer Disease The University of Texas Health Science Center at San Antonio|Mayo Clinic February 14 2020 Phase 1|Phase 2
NCT04155411 Recruiting Drug: Dasatinib Dasatinib|BCR-ABL|Chronic Myeloid Leukemia Shenzhen Second People''s Hospital December 1 2019 Phase 4
NCT04115059 Recruiting Drug: Dasatinib Waldenstrom Macroglobulinemia|DASATINIB Jorge J. Castillo MD|Bristol-Myers Squibb|Dana-Farber Cancer Institute November 4 2019 Phase 1
NCT03318770 Not yet recruiting Drug: Dasatinib and blinatumomab Acute Lymphoblastic Leukemia Gruppo Italiano Malattie EMatologiche dell''Adulto December 2018 --
NCT03625388 Recruiting Drug: Dasatinib Chronic Myelogenous Leukemia Hikma Pharmaceuticals LLC November 5 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Frequently Asked Questions

  • Question 1:

    What’s the difference between S1021 and S7782?

  • Answer:

    Usually, hydrate will be more stable and dissolve better than free base. But this compound (S1021) dissolves better in DMSO than hydrate one (S7782).

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID