Dasatinib Monohydrate

For research use only.

Catalog No.S7782 Synonyms: BMS-354825 Monohydrate

67 publications

Dasatinib Monohydrate Chemical Structure

Molecular Weight(MW): 506.02

Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.

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Selleck's Dasatinib Monohydrate has been cited by 67 publications

Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
Targets
Abl [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
c-Kit (D816V) [2]
(Cell-free assay)
c-Kit (wt) [2]
(Cell-free assay)
0.6 nM 0.8 nM 37 nM 79 nM
In vitro

Dasatinib is more effective than imatinib in inhibiting the proliferation of Ba/F3 cells expressing wild-type Bcr-Abl and Bcr-Abl mutants, with the exception of T315I. Dasatinib has a two-log (∼325-fold) increased potency relative to imatinib. Dasatinib potently inhibits wild-type Abl kinase and all mutants except T315I over a narrow range. Dasatinib directly targets wild-type and mutant Abl kinase domains and inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner. Dasatinib displays 325-fold greater potency compared with imatinib against cells expressing wild-type Bcr-Abl. [1] The percent of colonies of TgE bone marrow cells are decreased from 100% in untreated wells to 4.12% in Dasatinib treated wells. In the presence of Dasatinib, the difference in the percentage of colonies formed by WT and TgE bone marrow cells is statistically significant. Expression of LMP2A is able to promote B lymphocyte survival and proliferation, which can be inhibited by targeting Lyn and/or c-Abl kinases through Dasatinib. [3] Dasatinib treatment inhibits Src signaling, decreases growth, and induces cell cycle arrest and apoptosis in a subset of thyroid cancer cells. Treatment with increasing doses of Dasatinib (0.019 μM to 1.25 μM) for 3 days inhibits the growth of the C643, TPC1, BCPAP, and SW1736 cell lines by about 50% at low nanomolar concentrations, while higher concentrations are required to inhibit the growth of the K1 cell line. Treatment with 10 nM or 50 nM Dasatinib results in a 9-22% increase of cells in the G1 population among BCPAP and SW1736 and K1 cells, and a corresponding 7-18% decrease in the percentage of cells in the S phase. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K562 cell M3nqenBzd2yrZnXyZZRqd25iYYPzZZk> M4qyclczKGh? M1zoeGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iS{W2NkBk\WyuczDh[pRmeiB5MjDodpMtKEmFNUC9NE4xODFizszN Mo\3NVU3OTV3MUK=
WiDr cell M2jqT3Bzd2yrZnXyZZRqd25iYYPzZZk> NYjHUFV5PzJiaB?= Mn;6RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCZaVTyJINmdGy|IHHmeIVzKDd{IHjyd{whUUN3ME2wMlA2OiEQvF2= NY\1Rnl5OTV4MUW1NVI>
PC3 cell NEfkSZVRem:uaX\ldoF1cW:wIHHzd4F6 MmDYO|IhcA>? M4LBOWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUFOzJINmdGy|IHHmeIVzKDd{IHjyd{whUUN3ME2wMlAxQTRizszN Mlv4NVU3OTV3MUK=
MDA-MB-231 cell MUDQdo9tcW[ncnH0bY9vKGG|c3H5 MV63NkBp NF\jOm5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= NVTKWWR7OTV4MUW1NVI>
M07ep210 cell MkPHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEi1d4o1QCCq MWnHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDNNFdmeDJzMDDj[YxteyCjZoTldkA1QCCqcoOgZpkhYzOKXYTofY1q\GmwZTD1dJRic2ViYYPzZZktKEmFNUC9NE4xPyCwTR?= NYD2eYtrOTd7NU[wPFA>
K562 cell NGLVWJFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MknDOFghcA>? MoLuS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gT|U3OiClZXzsd{Bi\nSncjC0PEBpenNiYomgX|NJZXSqeX3p[Ilv\SC3cIThb4Uh[XO|YYmsJGlEPTB;MD6wNFEh|ryP MmTlNVc6PTZyOEC=
M07e cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWm0PEBp M2LwO2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG0xP2ViY3XscJMh[W[2ZYKgOFghcHK|IHL5JHs{UF22aIntbYRqdmVidYD0ZYtmKGG|c3H5MEBKSzVyPUCuNFAyOiEQvF2= NYC0dmF{OTd7NU[wPFA>
K562 cell NFvlNWxEgXSxdH;4bYNqfHliYYPzZZk> NGK3UoM4OiCq NUfpWnRVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUzV4MjDj[YxteyCjZoTldkA4OiCqcoOgZpkhX1OWLUigdoVi\2WwdDDiZZNm\CCPVGSgZZN{[XluIFnDOVA:OTJwOEOg{txO MUGyNlIyPzh5Nx?=
U937 cell Mnr5R5l1d3SxeHnjbZR6KGG|c3H5 M3v3OFczKGh? NVPHdXpSS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTl|NzDj[YxteyCjZoTldkA4OiCqcoOgZpkhX1OWLUigdoVi\2WwdDDiZZNm\CCPVGSgZZN{[XluIFnDOVA:OTNwNkOg{txO NEjuVlkzOjJzN{i3Oy=>
K562 cell NWX0OphVWHKxbHnm[ZJifGmxbjDhd5NigQ>? NY\yb3VJPzJiaB?= MV\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEt3NkKgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOFS{igZZN{[XluIFnDOVA:OC55IH7N NIXCfmEzOzV{MUCyNC=>
MDA-MB-435S cell NEfiW2dRem:uaX\ldoF1cW:wIHHzd4F6 NWT1TJJxPzJiaB?= NH3BSGZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi12M{XTJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVA:Oy57IN88US=> MmjPNlM2OjFyMkC=
NCI-H460 cell M3TGXXBzd2yrZnXyZZRqd25iYYPzZZk> NHPUOYs4OiCq M4H5[WFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME24Mlk6KM7:TR?= NH3J[mQzOzV{MUCyNC=>
NCI-H23 cell NHPSSZBRem:uaX\ldoF1cW:wIHHzd4F6 M4DVc|czKGh? NG\0SHNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JOjNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2yMlI4KM7:TR?= M4iwcFI{PTJzMEKw
A549 cell NIHoO2VRem:uaX\ldoF1cW:wIHHzd4F6 MWi3NkBp NIf2[JFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFG1OFkh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD1zMj62OkDPxE1? M4LJWVI{PTJzMEKw
T47D cell M2OxfHBzd2yrZnXyZZRqd25iYYPzZZk> MWG3NkBp MYTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFR2N1SgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjlizszN MYCyN|UzOTB{MB?=
HCT116 cell NXS3eVZxWHKxbHnm[ZJifGmxbjDhd5NigQ>? MojlO|IhcA>? MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFVEGxOkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxRTJwMzFOwG0> NH3xZ2UzOzV{MUCyNC=>
MCF7 cells NWrOS3hxWHKxbHnm[ZJifGmxbjDhd5NigQ>? MnnOO|IhcA>? M{TNd2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVPGO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxRTJwNUeg{txO Mon6NlM2OjFyMkC=
RXF 393NL cell NH76XotEgXSxdH;4bYNqfHliYYPzZZk> NV3lbYVUPCCmYYnz M4jCWGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHJZTiB|OUPOUEBk\WyuczDh[pRmeiB2IHThfZMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\yxiSVO1NF0zOS55IH7N MlfkNlMzPTNyN{S=
PRXF DU145 cell M3;6OWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXPNb4xbPCCmYYnz MWfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDQVnhHKESXMUS1JINmdGy|IHHmeIVzKDRiZHH5d{BjgSCycn;wbYRqfW1iaX;kbYRmKHO2YXnubY5oNCCLQ{WwQVAvODZ{MzFOwG0> MnexNlMzPTNyN{S=
LXFA 983L cell NFS4WYVEgXSxdH;4bYNqfHliYYPzZZk> MXO0JIRigXN? NVrETnBKS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVFiIQTC5PFNNKGOnbHzzJIFnfGW{IESg[IF6eyCkeTDwdo9xcWSrdX2gbY9lcWSnIIP0ZYlvcW6pLDDJR|UxRTV4LkWgcm0> MXOyN|I2OzB5NB?=
GXF251L cell NVLufGRqS3m2b4TvfIlkcXS7IHHzd4F6 NUiwUFdnPCCmYYnz MV7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDHXGYzPTGOIHPlcIx{KGGodHXyJFQh\GG7czDifUBxem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nMEBKSzVyPUKuNlUh|ryP NEjDOY8zOzJ3M{C3OC=>
CXF 1103L cell MmrCR5l1d3SxeHnjbZR6KGG|c3H5 MV[0JIRigXN? NFvoPJBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBEYEZiMUGwN2wh[2WubIOgZYZ1\XJiNDDkZZl{KGK7IIDyc5Bq\Gm3bTDpc4Rq\GVic4ThbY5qdmduIFnDOVA:PC5|NjFOwG0> NYjXd2NDOjN{NUOwO|Q>
PAXF 1657L cell NEDWR5dEgXSxdH;4bYNqfHliYYPzZZk> NX;VZlhZPCCmYYnz M4rWW2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHBCYEZiMU[1O2wh[2WubIOgZYZ1\XJiNDDkZZl{KGK7IIDyc5Bq\Gm3bTDpc4Rq\GVic4ThbY5qdmduIFnDOVA:OC5zMkGg{txO NXPMNIFvOjN{NUOwO|Q>
NCI-H1648 cell MlnqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mnu0TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2OFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB{MEGxJO69VQ>? NXXuS3FrW0GQR1XS
NCI-H1838 cell M{HpPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHvEUVVKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVg{QCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwM{C3N|Mh|ryP NY\wdohZW0GQR1XS
NCI-H2126 cell M2XaZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkLITY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjh5NUWyJO69VQ>? MneyV2FPT0WU
NCI-H2141 cell MnezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlLJTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxOFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPC55N{W0JO69VQ>? M{fmfnNCVkeHUh?=
NCI-H2107 cell Mnf6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mkm0TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNFch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Oy52OES3JO69VQ>? NEnt[lVUSU6JRWK=
NCI-H747 cell NWXXS2xST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDTZ2tLUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFc1PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEizOlIh|ryP MVvTRW5ITVJ?
NCI-H720 cell NXTsdI02T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnTITY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEeyNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjJ5M{Og{txO MoTOV2FPT0WU
NKM-1 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{myTWlvcGmkaYTpc44hd2ZiaIXtZY4hVkuPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuN|A5PTlizszN MYrTRW5ITVJ?
NMC-G1 cell M4\ISGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1zVcGlvcGmkaYTpc44hd2ZiaIXtZY4hVk2FLVexJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlEyPjB4IN88US=> M4HQ[HNCVkeHUh?=
NTERA-S-cl-D1 cell MlTIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnT2TY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkGyNlg{KM7:TR?= MWTTRW5ITVJ?
OCI-AML2 cell NVfQ[XRET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M33ReWlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVUvQDZzNUSg{txO MnSwV2FPT0WU
OCUB-M cell MoDqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGT3[lZKdmirYnn0bY9vKG:oIHj1cYFvKE:FVVKtUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU4xPDRzMjFOwG0> NFHi[XVUSU6JRWK=
OPM-2 cell NWT3N2xMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NELvNpNKdmirYnn0bY9vKG:oIHj1cYFvKE:STT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME20MlI4Pjh3IN88US=> Ml3YV2FPT0WU
OS-RC-2 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXvtb5l1UW6qaXLpeIlwdiCxZjDoeY1idiCRUz3SR{0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB{MEOg{txO NGe2V21USU6JRWK=
ONS-76 cell NHnSc3VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlfxTY5pcWKrdHnvckBw\iCqdX3hckBQVlNvN{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuOFI6PTFizszN MlzDV2FPT0WU
OVCAR-4 cell MnHBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVPZVmQ4UW6qaXLpeIlwdiCxZjDoeY1idiCRVlPBVk01KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjN5NEOzJO69VQ>? NV;CXHV1W0GQR1XS
NCI-H446 cell Ml\QS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXHzRmxnUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFQ1PiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC54Mke2JO69VQ>? MlW2V2FPT0WU
NCI-H510A cell NF:5dmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1\uU2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NVBCKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yQS5|OUezJO69VQ>? NYrFdpZXW0GQR1XS
PF-382 cell NEnpSlZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1;kc2lvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE4Pjd6IN88US=> Mkm1V2FPT0WU
NCI-H64 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUfx[4tZUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFY1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0zQS54MkWzJO69VQ>? MXfTRW5ITVJ?
PSN1 cell MmLMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJHBUVjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMES0O|Qh|ryP M4HJdHNCVkeHUh?=
QIMR-WIL cell NV;BRWlmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWnJcohq[mm2aX;uJI9nKGi3bXHuJHFKVVJvV1nMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlcxPjJ7IN88US=> NVnjSVVtW0GQR1XS
RL95-2 cell NFr0fY9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NInh[GVKdmirYnn0bY9vKG:oIHj1cYFvKFKOOUWtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yODN6IN88US=> NFnPbpJUSU6JRWK=
RCC10RGB cell NYWxdXJiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVTZW2s6UW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC52OUGxJO69VQ>? MVXTRW5ITVJ?
RKO cell MkH0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIr0S5dKdmirYnn0bY9vKG:oIHj1cYFvKFKNTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD61Nlk3PiEQvF2= NF:4UIRUSU6JRWK=
NCI-SNU-16 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2PXWGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLWPOWU0yPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QC53NkGyPEDPxE1? MUDTRW5ITVJ?
RPMI-6666 cell MmnkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvNk[2OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9O{4zPzB4NzFOwG0> NFnQd|hUSU6JRWK=
NEC8 cell NXXIVWpxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnfQTY5pcWKrdHnvckBw\iCqdX3hckBPTUN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12ND6zN|Yh|ryP NYS0R3ZjW0GQR1XS
RS4-11 cell M4XJT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{jDRmlvcGmkaYTpc44hd2ZiaIXtZY4hWlN2LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME23MlY2Pzh5IN88US=> M{D4dHNCVkeHUh?=
RXF393 cell MkDJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXTJcohq[mm2aX;uJI9nKGi3bXHuJHJZTjN7MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNlM2PyEQvF2= MXjTRW5ITVJ?
Raji cell M3;MfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYTlT3VZUW6qaXLpeIlwdiCxZjDoeY1idiCUYXrpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xN{44PDl5IN88US=> NX3hR25XW0GQR1XS
NOS-1 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwOlEzQSEQvF2= Mnr4V2FPT0WU
SBC-1 cell NWTkRpBsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX\pNnhIUW6qaXLpeIlwdiCxZjDoeY1idiCVQlOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NU42Pzl6NDFOwG0> M1HNXXNCVkeHUh?=
SF126 cell MlvyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MornTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6zOVQyKM7:TR?= NVXXO5pyW0GQR1XS
SF539 cell NVnGXm54T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYTJcohq[mm2aX;uJI9nKGi3bXHuJHNHPTN7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMz64OVU4KM7:TR?= MljtV2FPT0WU
SH-4 cell NG\LN25Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoPwTY5pcWKrdHnvckBw\iCqdX3hckBUUC12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG4OFE{KM7:TR?= M{Lpb3NCVkeHUh?=
OMC-1 cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVHJcohq[mm2aX;uJI9nKGi3bXHuJG9OSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1{Nz6xOFIzKM7:TR?= MXjTRW5ITVJ?
SIG-M5 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX3Jcohq[mm2aX;uJI9nKGi3bXHuJHNKTy2PNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;OT6wNlQ6OyEQvF2= M1HzWnNCVkeHUh?=
SJSA-1 cell M37wR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXlTY5pcWKrdHnvckBw\iCqdX3hckBUUlODLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUiuO|I5ODVizszN NHXBbW5USU6JRWK=
SK-LMS-1 cell NFHJbIFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NG\qeXJKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzNV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0{NjFzOEi2JO69VQ>? NHLofGlUSU6JRWK=
SK-NEP-1 cell M4Tzc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnnFTY5pcWKrdHnvckBw\iCqdX3hckBUUy2QRWCtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9PE45QTF3NTFOwG0> NIHzUXVUSU6JRWK=
SKM-1 cell NWj2e4tmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI\yRXNKdmirYnn0bY9vKG:oIHj1cYFvKFONTT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME25MlAyPzN2IN88US=> MWTTRW5ITVJ?
SK-PN-DW cell Mkm0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnPXTY5pcWKrdHnvckBw\iCqdX3hckBUUy2STj3EW{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|YvOTl2MzFOwG0> NUn2ZYpGW0GQR1XS
SK-UT-1 cell NVPLRoVyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWrJcohq[mm2aX;uJI9nKGi3bXHuJHNMNVWWLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUKuNVY3QTNizszN MoT6V2FPT0WU
SNB75 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH2zUWFKdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1PDN3IN88US=> MVfTRW5ITVJ?
REH cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEHLcINKdmirYnn0bY9vKG:oIHj1cYFvKFKHSDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MkCuOlM2PyEQvF2= NFS3O4JUSU6JRWK=
SNU-C2B cell NVm0U5lFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV3PXYtvUW6qaXLpeIlwdiCxZjDoeY1idiCVTmWtR|JDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yNjNyNUi5JO69VQ>? NUXC[pJZW0GQR1XS
RPMI-8866 cell NHHN[5dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mo\CTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLUi4OlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVE4NjR2NUWg{txO MlTIV2FPT0WU
SW872 cell Mn7OS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkC0NVYyKM7:TR?= M1S3W3NCVkeHUh?=
SW962 cell NWnJS|BvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1PiZmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVEzQTJizszN NEjSV4hUSU6JRWK=
SF268 cell NYrpb3ZGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYjONHFTUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4yPzRyNDFOwG0> M4fDVnNCVkeHUh?=
TE-1 cell MmDtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{e1N2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xNFU1KM7:TR?= NXLMSpFbW0GQR1XS
8-MG-BA cell MmTKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MljHTY5pcWKrdHnvckBw\iCqdX3hckA5NU2JLVLBJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE2PDV6IN88US=> NYLHTHU4W0GQR1XS
A101D cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1TKdWlvcGmkaYTpc44hd2ZiaIXtZY4hSTFyMVSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNFMxPDNizszN NV7n[4pSW0GQR1XS
A253 cell NIq1VYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUfFbmtoUW6qaXLpeIlwdiCxZjDoeY1idiCDMkWzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zMlc{OjR4IN88US=> M3LsRXNCVkeHUh?=
A3-KAW cell NFfPPVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGE{NUuDVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD65PFQ2OiEQvF2= NIrseIlUSU6JRWK=
A4-Fuk cell Mn71S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJGE1NU[3azDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;M{iuNVAxQSEQvF2= M{Szd3NCVkeHUh?=
A388 cell M3;zTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXXlO4VwUW6qaXLpeIlwdiCxZjDoeY1idiCDM{i4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA2ODl3IN88US=> M1P1OHNCVkeHUh?=
ACN cell NXfYem8yT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml71TY5pcWKrdHnvckBw\iCqdX3hckBCS05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwOEKyOVIh|ryP M{\hUHNCVkeHUh?=
A704 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIDWNoVKdmirYnn0bY9vKG:oIHj1cYFvKEF5MESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFE1QTFizszN MYPTRW5ITVJ?
ALL-PO cell MlzES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHrNRVZKdmirYnn0bY9vKG:oIHj1cYFvKEGOTD3QU{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVAvPzl|ODFOwG0> NUHhOJQ4W0GQR1XS
ARH-77 cell NVHGeoxsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnLOTY5pcWKrdHnvckBw\iCqdX3hckBCWkhvN{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUOuOFY6OTVizszN NHvYfYlUSU6JRWK=
SR cell NUDjXWhNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHXXXplKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD12LkS5PVU1KM7:TR?= MmO2V2FPT0WU
BB65-RCC cell NWe3N5hnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{G5NGlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ4NT3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODh{Mkeg{txO M2LFV3NCVkeHUh?=
BB49-HNC cell NWTk[pV{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHvnR5lKdmirYnn0bY9vKG:oIHj1cYFvKEKENEmtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjN6NUm5JO69VQ>? Ml22V2FPT0WU
BC-1 cell NYPsXIVOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGJENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTJ6Lk[1NUDPxE1? NXjLfmR1W0GQR1XS
BC-3 cell M4nJUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnrxTY5pcWKrdHnvckBw\iCqdX3hckBDSy1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zMj6xNVM5KM7:TR?= Mk\2V2FPT0WU
BL-41 cell M2\mTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVXSOVVjUW6qaXLpeIlwdiCxZjDoeY1idiCETD20NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4zQTF{MzFOwG0> MkjrV2FPT0WU
BL-70 cell MnHDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnLtTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFAxODB6MkG4JO69VQ>? NYXLdIlTW0GQR1XS
SW684 cell NYnmcYtHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVLjTVNtUW6qaXLpeIlwdiCxZjDoeY1idiCVV{[4OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4{PDl6IN88US=> M1rIeHNCVkeHUh?=
BOKU cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4L1VWlvcGmkaYTpc44hd2ZiaIXtZY4hSk:NVTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD60PVE{OyEQvF2= M3HOXXNCVkeHUh?=
SW954 cell MlnTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIW2S49KdmirYnn0bY9vKG:oIHj1cYFvKFOZOUW0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzQTJ5IN88US=> M2\tfnNCVkeHUh?=
C2BBe1 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4PjSGlvcGmkaYTpc44hd2ZiaIXtZY4hSzKEQnWxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA5OzB6IN88US=> MUDTRW5ITVJ?
BV-173 cell NH7uNJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGJXNTF5MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wNFAxODBzMEmg{txO MkjsV2FPT0WU
Becker cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXrTZ4NmUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODNyMEOg{txO MoHVV2FPT0WU
SW982 cell NE\JTmdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1LNZ2lvcGmkaYTpc44hd2ZiaIXtZY4hW1d7OEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFEyOTVizszN MoqxV2FPT0WU
697 cell MnfuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml[4TY5pcWKrdHnvckBw\iCqdX3hckA3QTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUm5PFch|ryP NHzEbmZUSU6JRWK=
TE-15 cell M4HaVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2WyUWlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFA2QDlzIN88US=> NIfOUY5USU6JRWK=
TE-11 cell M3jaeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkK0TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wO|g2QCEQvF2= MVzTRW5ITVJ?
TE-5 cell M2fsfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoPBTY5pcWKrdHnvckBw\iCqdX3hckBVTS13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLke5NVM6KM7:TR?= MkD2V2FPT0WU
TE-6 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlTHTY5pcWKrdHnvckBw\iCqdX3hckBVTS14IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLkKxNlI3KM7:TR?= MVHTRW5ITVJ?
TE-9 cell MnHRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4jINmlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD64O|U{OiEQvF2= NUW2fmJtW0GQR1XS
TGBC24TKB cell NGqweYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1HLdWlvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{K0WGtDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB2N{[xJO69VQ>? MXXTRW5ITVJ?
TGW cell M4fGVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkSwTY5pcWKrdHnvckBw\iCqdX3hckBVT1diY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFzLkK4Nlgh|ryP NIHNNo5USU6JRWK=
TK10 cell M1Xw[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGH5S4FKdmirYnn0bY9vKG:oIHj1cYFvKFSNMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFEyPzRizszN NVzETHlIW0GQR1XS
TGBC1TKB cell NFvGd25Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{DqVGlvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{HUT2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODZzNkSg{txO NXW0S3VzW0GQR1XS
A498 cell M3WzNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2nxcGlvcGmkaYTpc44hd2ZiaIXtZY4hSTR7ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wO|I5PCEQvF2= MV3TRW5ITVJ?
UACC-257 cell M3j1T2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4faV2lvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVEzNjlzOUig{txO MVzTRW5ITVJ?
U-87-MG cell NFjV[m1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmDVTY5pcWKrdHnvckBw\iCqdX3hckBWNTh5LV3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zNE44PjZizszN M1G3[nNCVkeHUh?=
BB30-HNC cell M2\RSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFq0bIdKdmirYnn0bY9vKG:oIHj1cYFvKEKEM{CtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjB3NEO3JO69VQ>? MUXTRW5ITVJ?
no-10 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\JS2RGUW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4{OTl|MTFOwG0> M{[zTHNCVkeHUh?=
CAS-1 cell M2XuOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1\WV2lvcGmkaYTpc44hd2ZiaIXtZY4hS0GVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuOFA6QTJizszN MlnVV2FPT0WU
CGTH-W-1 cell M4LBW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUDJcohq[mm2aX;uJI9nKGi3bXHuJGNIXEhvVz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{PTR6IN88US=> M{HTW3NCVkeHUh?=
TE-10 cell M{na[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Moj4TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wOlM2PyEQvF2= M1HocXNCVkeHUh?=
COLO-684 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2TNdGlvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz22PFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVQ3NjJ{NUig{txO NF3ISIVUSU6JRWK=
TE-12 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXXJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCxPFYyKM7:TR?= MV;TRW5ITVJ?
COR-L279 cell Mn\lS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVvQcZZTUW6qaXLpeIlwdiCxZjDoeY1idiCFT2KtUFI4QSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:PDBwMki1NkDPxE1? NGPKR2FUSU6JRWK=
TE-8 cell MlLYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYT6NY95UW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyPTd4IN88US=> MkPhV2FPT0WU
CP66-MEL cell M1fvc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYPJcohq[mm2aX;uJI9nKGi3bXHuJGNRPjZvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE6PTNzIN88US=> MoXGV2FPT0WU
CTV-1 cell NXPsUJJXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3jQTWlvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFAxODRyM{[g{txO NWflcXF1W0GQR1XS
VA-ES-BJ cell NHHvbYJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWDJcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{QTB{IN88US=> MmTIV2FPT0WU
D-263MG cell NUHrdHVwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXfJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuN|YzOjRizszN NVfYdJVwW0GQR1XS
D-336MG cell NVXM[mlyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIHPe5RKdmirYnn0bY9vKG:oIHj1cYFvKERvM{O2UWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODB4Mkm4JO69VQ>? MUjTRW5ITVJ?
D-502MG cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXjJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTB{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNlM{PzZizszN MnvZV2FPT0WU
DJM-1 cell M{LrbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;mcJdwUW6qaXLpeIlwdiCxZjDoeY1idiCGSl2tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9Ok41QDV3ODFOwG0> NEDEbYRUSU6JRWK=
no-11 cell M2Tmb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWXJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkWwNlI5KM7:TR?= NF3jVm9USU6JRWK=
DMS-153 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\uSHZXUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVU{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0yPC5yMEK4JO69VQ>? NEfEW2ZUSU6JRWK=
DSH1 cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHzPSmpKdmirYnn0bY9vKG:oIHj1cYFvKESVSEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNlQxODFizszN M{nqNXNCVkeHUh?=
DU-4475 cell NGXKXZhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF60dpNKdmirYnn0bY9vKG:oIHj1cYFvKESXLUS0O|Uh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvOjF4NUKg{txO NV;MXm95W0GQR1XS
EB-3 cell NHjYbWRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVH0VZl1UW6qaXLpeIlwdiCxZjDoeY1idiCHQj2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zOE4{OTF6IN88US=> NXzORWpLW0GQR1XS
EHEB cell NXnteoFoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVn1RZJnUW6qaXLpeIlwdiCxZjDoeY1idiCHSFXCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNE4xPjV4IN88US=> MV;TRW5ITVJ?
COLO-829 cell NF\pUFBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1y2bWlvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz24Nlkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTJ{MUOg{txO M2P5UXNCVkeHUh?=
CP67-MEL cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlHCTY5pcWKrdHnvckBw\iCqdX3hckBEWDZ5LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4zODR6ODFOwG0> MoLjV2FPT0WU
ES8 cell NVPjdWVHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{jpRmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1|Mj6xNlUzKM7:TR?= MmfnV2FPT0WU
EVSA-T cell MnTNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHHP[XBKdmirYnn0bY9vKG:oIHj1cYFvKEWYU1GtWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9PU4zPzd7MzFOwG0> MVnTRW5ITVJ?
ES4 cell M4e2S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmHwTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwMEWxOFUh|ryP MoG0V2FPT0WU
ETK-1 cell M3fOSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYHLRnlSUW6qaXLpeIlwdiCxZjDoeY1idiCHVFutNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOjh|MjFOwG0> NH;DRZhUSU6JRWK=
ES6 cell NUPncIk4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFzIUGZKdmirYnn0bY9vKG:oIHj1cYFvKEWVNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6wN|E6OyEQvF2= M{fCNHNCVkeHUh?=
EW-24 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoL2TY5pcWKrdHnvckBw\iCqdX3hckBGXy1{NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD63PFE3PSEQvF2= MVfTRW5ITVJ?
EoL-1-cell cell Mo\5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEfSbHJKdmirYnn0bY9vKG:oIHj1cYFvKEWxTD2xMYNmdGxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMECwNFE{ODlizszN NFrQe|ZUSU6JRWK=
Calu-6 cell M1jyc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVnJcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;Mz6wOVc1OSEQvF2= M1fqXHNCVkeHUh?=
GAK cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGdCUyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OzFwMk[4OkDPxE1? NXfCZ4tSW0GQR1XS
D-247MG cell NGX4T2ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{niNWlvcGmkaYTpc44hd2ZiaIXtZY4hTC1{NEfNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9Ok4yOjVzOTFOwG0> NH3hU|RUSU6JRWK=
GB-1 cell M1LhVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlzWTY5pcWKrdHnvckBw\iCqdX3hckBISi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCyNVU4KM7:TR?= MWHTRW5ITVJ?
GI-ME-N cell M3\zO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHjjXVRKdmirYnn0bY9vKG:oIHj1cYFvKEeLLV3FMW4h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODZzMUig{txO MljlV2FPT0WU
GCIY cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH\aemxKdmirYnn0bY9vKG:oIHj1cYFvKEeFSWmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFk3PTZizszN M4myZXNCVkeHUh?=
GT3TKB cell MlvhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoS1TY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUmuN|U2PDZizszN MXHTRW5ITVJ?
HC-1 cell NH2zfo9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3f5TmlvcGmkaYTpc44hd2ZiaIXtZY4hUENvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MkSuOVU2OSEQvF2= NGXvc2tUSU6JRWK=
HAL-01 cell M4LZUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml:yTY5pcWKrdHnvckBw\iCqdX3hckBJSUxvMEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUG5Mlc2PDNizszN MWfTRW5ITVJ?
HCC1187 cell NWD6eWRHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUnJcohq[mm2aX;uJI9nKGi3bXHuJGhESzFzOEegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUO1MlgxPTJizszN M3zSSXNCVkeHUh?=
DEL cell MnjkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofDTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTRzLkmwPFYh|ryP M{e1NXNCVkeHUh?=
HCC1599 cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPoTY5pcWKrdHnvckBw\iCqdX3hckBJS0NzNUm5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2zNk4{OzJ3IN88US=> NX\UXWhTW0GQR1XS
DOHH-2 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1flTWlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAyPzF7IN88US=> Mki2V2FPT0WU
HCC2157 cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M37WVGlvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkG1O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9N|cvQTl2NjFOwG0> MU\TRW5ITVJ?
HCE-4 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{TUW2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOHLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNlY1OzlizszN NV3kcJI6W0GQR1XS
HCE-T cell M1SwXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{TrbWlvcGmkaYTpc44hd2ZiaIXtZY4hUEOHLWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuOVY4OTRizszN M1W1XXNCVkeHUh?=
HEL cell M{jId2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlPuTY5pcWKrdHnvckBw\iCqdX3hckBJTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFyLkS3O|Yh|ryP MnnBV2FPT0WU
EM-2 cell NFzXWHdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGVONTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMECwNFAyODd6IN88US=> NFy2[3pUSU6JRWK=
HT-144 cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlnvTY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuOVM3ODlizszN M3rSVHNCVkeHUh?=
EW-16 cell M4TqPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnL0TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD63OlE4QCEQvF2= NWDxUoM2W0GQR1XS
IA-LM cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH3ydHJKdmirYnn0bY9vKG:oIHj1cYFvKEmDLVzNJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2xNk41PDR3IN88US=> MoSzV2FPT0WU
IST-MEL1 cell NYHuUXlwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVnJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2PRVyxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlE{PDVizszN M1:5dXNCVkeHUh?=
IST-MES1 cell M3nKcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4PzVmlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FV|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODh3NUKg{txO MUDTRW5ITVJ?
GI-1 cell MoLSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYLJcohq[mm2aX;uJI9nKGi3bXHuJGdKNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTFwM{[yNkDPxE1? NWnDS4VRW0GQR1XS
IST-SL2 cell M4TsR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGT5[FVKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPTB|MEKg{txO NV3GUVFZW0GQR1XS
JVM-2 cell M4G2XGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFT3V4tKdmirYnn0bY9vKG:oIHj1cYFvKEqYTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yMlM3Ojh2IN88US=> Mk[1V2FPT0WU
JVM-3 cell MoXtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXjJcohq[mm2aX;uJI9nKGi3bXHuJGpXVS1|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1|Nz6yN|M5KM7:TR?= MlK4V2FPT0WU
KALS-1 cell NX;EVpNYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4\PUmlvcGmkaYTpc44hd2ZiaIXtZY4hU0GOUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA6PDlizszN NEHSfZRUSU6JRWK=
KARPAS-422 cell MnXPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1jzUGlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5|M{m5O{DPxE1? NYHLZlN{W0GQR1XS
JiyoyeP-2003 cell MorrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH7kc5BKdmirYnn0bY9vKG:oIHj1cYFvKEqreX;5[XAuOjByMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MT63N|Q3PiEQvF2= M3n1W3NCVkeHUh?=
KARPAS-45 cell NUflVYdrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlvRTY5pcWKrdHnvckBw\iCqdX3hckBMSVKSQWOtOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVcvPTF4N{Gg{txO M2X6T3NCVkeHUh?=
KGN cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVHCUG41UW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFE6PDJizszN MVXTRW5ITVJ?
KLE cell Ml7oS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYXiRWF4UW6qaXLpeIlwdiCxZjDoeY1idiCNTFWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVE{OTdizszN NFLmN2pUSU6JRWK=
KNS-42 cell M4DCfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlPsTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUGuNlQ1OTJizszN M3X1bXNCVkeHUh?=
KNS-81-FD cell M2jLNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmnRTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvOEGtSmQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVI{NjF2NjFOwG0> M3H0OHNCVkeHUh?=
KP-N-YS cell MojpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2LrPWlvcGmkaYTpc44hd2ZiaIXtZY4hU1BvTj3ZV{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NVIvQTJ6MzFOwG0> NELQPXlUSU6JRWK=
HOP-62 cell NFf4SWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFi2[JVKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xOTh|NDFOwG0> M{HObHNCVkeHUh?=
KURAMOCHI cell M1XOb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVjKTphOUW6qaXLpeIlwdiCxZjDoeY1idiCNVWLBUW9EUEliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMEO0PFch|ryP NInnS25USU6JRWK=
HUTU-80 cell NWn1VmI2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXHxTldyUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjNzNEKg{txO NULtepM2W0GQR1XS
LAMA-84 cell NFHHOo5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NE\mTmxKdmirYnn0bY9vKG:oIHj1cYFvKEyDTVGtPFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODByMECzNlA4KM7:TR?= M1;2WXNCVkeHUh?=
LB1047-RCC cell MnfVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWPBOplXUW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwPVg5PyEQvF2= MkTCV2FPT0WU
LB2518-MEL cell MoPDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEPjWGpKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkWxPE1OTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMUSxOlIh|ryP NEPXNVhUSU6JRWK=
LB373-MEL-D cell NFXsRWRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHzIbJVKdmirYnn0bY9vKG:oIHj1cYFvKEyEM{ezMW1GVC2GIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkiyOVA5KM7:TR?= MWnTRW5ITVJ?
LB771-HNC cell M2DOTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NE[3c4hKdmirYnn0bY9vKG:oIHj1cYFvKEyEN{exMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:Oi53N{W1NUDPxE1? MkjTV2FPT0WU
LB996-RCC cell NYK4SWRFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIrpTW9KdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:OC5yMEm5NVIh|ryP M2SwXXNCVkeHUh?=
LC-2-ad cell NEDXU3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFm4W5dKdmirYnn0bY9vKG:oIHj1cYFvKEyFLUKtZYQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvODJ3OE[g{txO M1LGSXNCVkeHUh?=
J-RT3-T3-5 cell NVGwVlhrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJGouWlR|LWSzMVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVgvQTZ3Mkmg{txO NYm3TZpOW0GQR1XS
LP-1 cell NVizO|ZpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnjlTY5pcWKrdHnvckBw\iCqdX3hckBNWC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD15LkW0O|gzKM7:TR?= MWfTRW5ITVJ?
K-562 cell NFu0WllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXrJcohq[mm2aX;uJI9nKGi3bXHuJGsuPTZ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkCwNFAxODJ4NU[g{txO MV3TRW5ITVJ?
LS-123 cell M{H4W2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUHJcohq[mm2aX;uJI9nKGi3bXHuJGxUNTF{MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xOFA3PCEQvF2= NGjhO|VUSU6JRWK=
K5 cell NWfGUY9TT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHznOZhKdmirYnn0bY9vKG:oIHj1cYFvKEt3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1yLkG2OFg6KM7:TR?= MYHTRW5ITVJ?
LS-411N cell MnryS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnjSXBKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUSxNW4h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVQ5NjR5NEig{txO M2fIOnNCVkeHUh?=
KG-1 cell M3LVWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYDJcohq[mm2aX;uJI9nKGi3bXHuJGtINTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTRwNkC4OFUh|ryP MkfHV2FPT0WU
KINGS-1 cell MlvzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXLUSJFNUW6qaXLpeIlwdiCxZjDoeY1idiCNSV7HV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjF4Nk[2JO69VQ>? MoXUV2FPT0WU
LXF-289 cell NF7UOZdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml3hTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA{QTV4IN88US=> MluwV2FPT0WU
MC116 cell NVjROm1nT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI\FXZRKdmirYnn0bY9vKG:oIHj1cYFvKE2FMUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlEyPDFizszN MWXTRW5ITVJ?
KS-1 cell Ml3US5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWjrTop5UW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAzPzNizszN MXvTRW5ITVJ?
KU812 cell M13Gcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4DDXWlvcGmkaYTpc44hd2ZiaIXtZY4hU1V6MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVE5QDNizszN M4PUUXNCVkeHUh?=
MEG-01 cell M1m4TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2PCTWlvcGmkaYTpc44hd2ZiaIXtZY4hVUWJLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlAxODByOUiwOUDPxE1? M4ry[nNCVkeHUh?=
MFH-ino cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mni2TY5pcWKrdHnvckBw\iCqdX3hckBOTkhvaX7vJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2wMlA1PzJ2IN88US=> MUPTRW5ITVJ?
L-540 cell M1z1cmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{jOXmlvcGmkaYTpc44hd2ZiaIXtZY4hVC13NECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUG1MlA3PzFizszN NH7aWGtUSU6JRWK=
MHH-NB-11 cell MoL5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGW0N2lKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3ORk0yOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:PDNwMEixPEDPxE1? MlLHV2FPT0WU
MMAC-SF cell NIXyN4NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{H0NGlvcGmkaYTpc44hd2ZiaIXtZY4hVU2DQz3TSkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9PE44QTNyNzFOwG0> NGrJeYFUSU6JRWK=
LB2241-RCC cell M2nlZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn:wTY5pcWKrdHnvckBw\iCqdX3hckBNSjJ{NEGtVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF06NjB{MEGyJO69VQ>? MmH5V2FPT0WU
LB831-BLC cell NF;IOHVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV:zfVFOUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTBwMES2NFkh|ryP M1:zSXNCVkeHUh?=
MOLT-16 cell NETNWXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1zHNmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NlkvPjJ7MjFOwG0> NWDOfpk5W0GQR1XS
LC-1F cell NF\wWWRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEHWXXBKdmirYnn0bY9vKG:oIHj1cYFvKEyFLUHGJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yO{4{OjR3IN88US=> MUTTRW5ITVJ?
MOLT-4 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnf2TY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUK2MlY4PTNizszN MVvTRW5ITVJ?
MZ1-PC cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnjjTY5pcWKrdHnvckBw\iCqdX3hckBOYjFvUFOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNFMyOTlizszN M2G5XnNCVkeHUh?=
MONO-MAC-6 cell MlnPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1XCS2lvcGmkaYTpc44hd2ZiaIXtZY4hVU:QTz3NRWMuPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LlnDOVA:QC5{N{C2OkDPxE1? Mnv3V2FPT0WU
MZ2-MEL cell MlvuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIOzN4JKdmirYnn0bY9vKG:oIHj1cYFvKE2cMj3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOjh3M{eg{txO M4nhOXNCVkeHUh?=
MPP-89 cell NHnUPIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFyyVmhKdmirYnn0bY9vKG:oIHj1cYFvKE2SUD24PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4xPDB2OTFOwG0> Ml[1V2FPT0WU
MZ7-mel cell Moj1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFHhblJKdmirYnn0bY9vKG:oIHj1cYFvKE2cNz3t[Ywh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvPDd7MUGg{txO NIWyWIZUSU6JRWK=
LOXIMVI cell NI\je29Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{\kNmlvcGmkaYTpc44hd2ZiaIXtZY4hVE:[SV3WTUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NkmFNUC9NE4{OTVyMzFOwG0> MlToV2FPT0WU
NALM-6 cell NGHPTIVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVTFcpZoUW6qaXLpeIlwdiCxZjDoeY1idiCQQVzNMVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVAvOTl{OUWg{txO Ml7sV2FPT0WU
NB13 cell MoPuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmXOTY5pcWKrdHnvckBw\iCqdX3hckBPSjF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zOT60PFc4KM7:TR?= NWTlZ4J7W0GQR1XS
NB5 cell NVzBdIlyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{PnZWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJ3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD1zLkO5PFI4KM7:TR?= M1;2RnNCVkeHUh?=
NB17 cell NFLG[mtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXXJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTNwNkO4OFch|ryP MVfTRW5ITVJ?
NCCIT cell MonYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGj6ZY1KdmirYnn0bY9vKG:oIHj1cYFvKE6FQ1nUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZkvUUN3ME2yMlg3PjF4IN88US=> MUnTRW5ITVJ?
NB69 cell M2jad2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1z3XGlvcGmkaYTpc44hd2ZiaIXtZY4hVkJ4OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MD6xOFQ{PiEQvF2= M3fmbHNCVkeHUh?=
NCI-H1304 cell NIToeoNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX\GNoZ7UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{ODRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeT7JR|UxRTJ6LkG2Nlgh|ryP MknoV2FPT0WU
NCI-H1395 cell M3vGe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnXjTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigS6LQ{WwQVQzNjBzNkOg{txO MnewV2FPT0WU
MHH-PREB-1 cell NV;Yd|RVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkOyTY5pcWKrdHnvckBw\iCqdX3hckBOUEhvUGLFRk0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjd2NE[5JO69VQ>? NXvQeZFUW0GQR1XS
MLMA cell NUTaSnJIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIfNTJJKdmirYnn0bY9vKG:oIHj1cYFvKE2OTVGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfU5KSzVyPUCuNVQxOzJizszN NH62R5hUSU6JRWK=
MN-60 cell NHfWUJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmLKTY5pcWKrdHnvckBw\iCqdX3hckBOVi14MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MmlEPTB;MUWuNVk4QSEQvF2= MX;TRW5ITVJ?
MV-4-11 cell MmXqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NULSOmUzUW6qaXLpeIlwdiCxZjDoeY1idiCPVj20MVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF01NjN4NEW0JO69VQ>? Mn:3V2FPT0WU
NB6 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4S2e2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmuTWM2OD17LkmyNlU6KM7:TR?= M{PiS3NCVkeHUh?=
NCI-H1355 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2j3dWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XlwSVO1NF0xNjFzMEK4JO69VQ>? NYrDV2hzW0GQR1XS

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
phospho-c-Abl(Tyr245) / phospho-c-Src(Tyr416) ; 

PubMed: 23049975     


Protein levels of phosphorylated c-Abl (Tyr245), c-Abl, phosphorylated c-Src (Tyr416), c-Src, and GAPDH in NSC-34 cells overexpressing human wild-type or mutant SOD1s treated with various concentrations of dasatinib were measured by western blot. Cells were cultured in serum-free culture medium with doxycycline (Dox, 2 µg/ml), and western blot was performed at 24 h after dasatinib addition.

p27 / p21; 

PubMed: 20145167     


Dasatnib induced cell cycle arrest. Dasatinib induced growth arrest, shown as a cell cycle distribution graph in the lower panel, correlated with increased p27 and p21 levels. Western blotting for levels of p27 and p21 was performed on protein lysates of THP-1 cells treated for 48 hours with indicated doses of dasatinib or DMSO. Detection of actin served as control for comparable protein loading.

cleaved caspase 3 ; 

PubMed: 20145167     


Dasatinib induced apoptosis. Dasatinib causes apoptosis in Mo7e-KitD816H cells as detected by cleavage of caspase 3. Whole cell lysates were prepared after 24 hour treatment with dasatinib. Caspase 3 and cleaved capase 3 were analyzed by western blotting. Actin serves as loading control.

p-FAK/p-STAT3; 

PubMed: 23721490     


The effect of dasatinib in cell signalling. Western blot analysis with phosphorylated Src, FAK, Stat3, Akt and MAPK in HCC cell lines after 24 hours treatment of dasatinib. The cell lines were arranged according to their IC50 to dasatinib. The top three were most sensitive, the bottom 3 were least sensitive.

23049975 20145167 23721490
Growth inhibition assay
Cell viability; 

PubMed: 23721490     


9 HCC cell lines were exposed to the dedicated concentrations of dasatinib for 72 hours, and IC50 was tested by MTS. Results represent the mean (± SD) of three experiments.

23721490
Immunofluorescence
SRC / Met; 

PubMed: 26517812     


Immunocytochemistry of SRC and Met localization. Cellular localization of SRC and Met following treatment for 48 h with dasatinib, crizotinib or combination in A. LN-18 and B. U373 cells. Scale bar denotes 10 μm. Nuclei were visualized by DAPI while SRC and Met were labeled with a fluorescein and Texas-red conjugated secondary antibodies, respectively.

α-tubulin; 

PubMed: 26517812     


Combination of dasatinib and crizotinib impedes the formation of the α-tubulin-labeled mitotic spindle. LN-18 cells were treated with dasatinib 0.2 μM, crizotinib 4 μM or their combination for 48 h. Mitotic spindle were visualized using α-tubulin antibody conjugated to a fluorescein-labeled secondary antibody. Nuclei were stained by DAPI. The scale bar denotes 10 μm.

F-actin / Actinin-4 / Paxillin; 

PubMed: 31053734     


Conditionally immortalized differentiated podocytes treated for one-hour with 2 µM kinase inhibitor were stained for F-actin (phalloidin), α-actinin-4, paxillin, and nuclei (Hoechst 33342) to assess cytoskeletal and focal adhesion architecture (scale bars = 50 µm). Podocytes treated with dasatinib showed a marked decrease in cell-to-cell contacts, cell size and number of focal adhesions.

26517812 31053734
ELISA
TNF-α; 

PubMed: 17684099     


U937 cells were differentiated with vitamin D3, pretreated with the indicated concentrations of drugs for 1 h and stimulated with LPS for 6 h. TNF-α secretion was measured by ELISA. The graph shows the mean of two experiments done in duplicate.

E-selectin; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of E-selectin was determined using ELISA (n = 3, ±SEM).

VCAM-1; 

PubMed: 31110200     


HAoECs were treated with DMSO, a dual FAK/Pyk2 inhibitor (PF-271, 2.5 μM), a Src inhibitor (Dasatinib, 1 μM), or a FAK inhibitor (PF-228, 10 μM) for 1 h prior to TNF-α (10 ng/ml, 6 h) stimulation. Expression levels of VCAM-1 was determined using ELISA (n = 3, ±SEM).

17684099 31110200
In vivo Dasatinib reverses splenomegaly in LMP2A/MYC double transgenic mice. Dasatinib specifically prevents colony formation by LMP2A expressing bone marrow B cells and decreased spleen size in the TgE mice. Spleen mass is significantly decreased among Dasatinib treated Tg6/λ-MYC mice when compared to the control group. Dasatinib inhibits lymphadenopathy in LMP2A/MYC double transgenic mice. Dasatinib reverses splenomegaly in Rag1KO mice engrafted with tumor cells from LMP2A/MYC double transgenic mice. Dasatinib therapy inhibits Lyn phosphorylation in B lymphocyte tumors expressing LMP2A. [3]

Protocol

Kinase Assay:

[1]

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Kinase autophosphorylation assays:

Kinase assays using wild-type and mutant glutathione S-transferase (GST)-Abl fusion proteins (c-Abl amino acids 220-498) are done. GST-Abl fusion proteins are released from glutathione-Sepharose beads before use; the concentration of ATP is 5 μM. Immediately before use in kinase autophosphorylation and in vitro peptide substrate phosphorylation assays, GST-Abl kinase domain fusion proteins are treated with LAR tyrosine phosphatase. After 1-hour incubation at 30 °C, LAR phosphatase is inactivated by addition of sodium vanadate (1 mM). Immunoblot analysis comparing untreated GST-Abl kinase to dephosphorylated GST-Abl kinase is routinely done using phosphotyrosine-specific antibody 4G10 to confirm complete (>95%) dephosphorylation of tyrosine residues and c-Abl antibody CST 2862 to confirm equal loading of GST-Abl kinase. The Dasatinib concentration range is extended to 1,000 nM for mutant T315I. These same inhibitor concentrations are used for the in vitro peptide substrate phosphorylation assays. The three inhibitors are tested over these same concentration ranges against GST-Src kinase and GST-Lyn kinase.
Cell Research:

[1]

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  • Cell lines: Ba/F3 cell lines
  • Concentrations: ~32 nM
  • Incubation Time: 72 hours
  • Method:

    Ba/F3 cell lines are seeded in triplicate and incubated with escalating concentrations of Dasatinib for 72 hours. Proliferation is measured using a methanethiosulfonate-based viability assay. IC50 and IC90 values are reported as the mean of three independent experiments done in quadruplicate. The inhibitor concentration ranges are 0 nM to 32 nM (Dasatinib). The Dasatinib concentration range is extended to 200 nM for mutant T315I.


    (Only for Reference)
Animal Research:

[3]

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  • Animal Models: EμLMP2A (TgE and Tg6 strains), MYC (λ-MYC), and LMP2A/λ-MYC double transgenic mice (Tg6/λ-MYC)
  • Dosages: 30 mg/kg
  • Administration: Administered via i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 21 mg/mL warmed (41.5 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+dd H2O
For best results, use promptly after mixing.
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 506.02
Formula

C22H28ClN7O3S

CAS No. 863127-77-9
Storage powder
in solvent
Synonyms BMS-354825 Monohydrate
Smiles O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04063124 Suspended Drug: Dasatinib + Quercetin Alzheimer Disease The University of Texas Health Science Center at San Antonio|Mayo Clinic February 14 2020 Phase 1|Phase 2
NCT04155411 Recruiting Drug: Dasatinib Dasatinib|BCR-ABL|Chronic Myeloid Leukemia Shenzhen Second People''s Hospital December 1 2019 Phase 4
NCT04115059 Recruiting Drug: Dasatinib Waldenstrom Macroglobulinemia|DASATINIB Jorge J. Castillo MD|Bristol-Myers Squibb|Dana-Farber Cancer Institute November 4 2019 Phase 1
NCT03318770 Not yet recruiting Drug: Dasatinib and blinatumomab Acute Lymphoblastic Leukemia Gruppo Italiano Malattie EMatologiche dell''Adulto December 2018 --
NCT03625388 Recruiting Drug: Dasatinib Chronic Myelogenous Leukemia Hikma Pharmaceuticals LLC November 5 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Frequently Asked Questions

  • Question 1:

    What’s the difference between S1021 and S7782?

  • Answer:

    Usually, hydrate will be more stable and dissolve better than free base. But this compound (S1021) dissolves better in DMSO than hydrate one (S7782).

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID