Liver X Receptor

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2630 GW3965 HCl <1 mg/mL 16 mg/mL <1 mg/mL
S7076 T0901317 <1 mg/mL 96 mg/mL 96 mg/mL
S8689 RGX-104 100 mg/mL <1 mg/mL
S8390 LXR-623 (WAY-252623) <1 mg/mL 84 mg/mL 84 mg/mL
S7934 SR9243 <1 mg/mL <1 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations

GW3965 HCl

GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM in cell-free assays, respectively.



T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively.



RGX-104 is a orally bioavailable liver X receptor agonist that modulates innate immunity via transcriptional activation of the ApoE gene.


LXR-623 (WAY-252623)

LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.



SR9243 is a potent and selective LXR inverse agonist.