Immunology & Inflammation related

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2286 Cyclosporin A <1 mg/mL 100 mg/mL 100 mg/mL
S1211 Imiquimod <1 mg/mL 1 mg/mL <1 mg/mL
S3032 Bindarit <1 mg/mL 64 mg/mL 64 mg/mL
S1407 Bimatoprost <1 mg/mL 36 mg/mL 83 mg/mL
S1439 Tranilast <1 mg/mL 66 mg/mL <1 mg/mL
S4753 Ganoderic acid A <1 mg/mL 100 mg/mL 100 mg/mL
S8522 Compstatin 100 mg/mL -1 mg/mL -1 mg/mL
S8141 Cl-amidine 70 mg/mL 84 mg/mL 84 mg/mL
S8291 Atractylenolide I <1 mg/mL 46 mg/mL 46 mg/mL
S8301 AS101 <1 mg/mL 62 mg/mL <1 mg/mL
S4690 Escin <1 mg/mL 66 mg/mL <1 mg/mL
S4529 Idramantone 33 mg/mL 33 mg/mL 33 mg/mL
S8097 C-DIM12 <1 mg/mL 71 mg/mL 71 mg/mL
S4169 Teriflunomide <1 mg/mL 32 mg/mL ,1 mg/mL
S2413 Geniposidic acid <1 mg/mL 16 mg/mL 2 mg/mL
S1508 Alprostadil <1 mg/mL 71 mg/mL 71 mg/mL
S1939 (-)-Tetramisole 48 mg/mL <1 mg/mL <1 mg/mL
S2787 Laquinimod <1 mg/mL 61 mg/mL 1 mg/mL
S2910 Tempol 34 mg/mL 34 mg/mL 34 mg/mL
S1829 Pranlukast <1 mg/mL 11 mg/mL <1 mg/mL
S1514 Cyclosporine <1 mg/mL 100 mg/mL 100 mg/mL
S3062 Diclofenac Potassium 10 mg/mL 69 mg/mL <1 mg/mL
S7515 VGX-1027 <1 mg/mL 41 mg/mL 41 mg/mL
S4098 Halcinonide <1 mg/mL 90 mg/mL 4 mg/mL
S1823 Fenoprofen Calcium <1 mg/mL 105 mg/mL 10 mg/mL
S7211 PF-04418948 <1 mg/mL 81 mg/mL <1 mg/mL
S4152 Ethamsylate 53 mg/mL 53 mg/mL <1 mg/mL
S4165 Benzydamine HCl 69 mg/mL 69 mg/mL 69 mg/mL
S2400 Rheic Acid <1 mg/mL <1 mg/mL <1 mg/mL
S7448 CORM-3 <1 mg/mL 38 mg/mL <1 mg/mL
S7516 Y-320 <1 mg/mL 11 mg/mL <1 mg/mL
S3027 Fenoprofen calcium hydrate <1 mg/mL 48 mg/mL 18 mg/mL
S2350 Rutin <1 mg/mL 100 mg/mL 2 mg/mL
S7434 TAPI-1 60 mg/mL 99 mg/mL 99 mg/mL
Catalog No. Information Product Use Citations Product Validations
A2001New

Ipilimumab

Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.

S2286

Cyclosporin A

Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.

S3032

Bindarit

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

S4753New

Ganoderic acid A

Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.

S8522New

Compstatin

Compstatin binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.

S8291New

Atractylenolide I

Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.

S1514

Cyclosporine

Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.

S7434

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

S8301New

AS101

AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

S2787

Laquinimod

Laquinimod is a potent immunomodulator. Phase 3.

S7515

VGX-1027

VGX-1027 is an orally active immunomodulator. Phase 1.

S7516

Y-320

Y-320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.

S1211

Imiquimod

Imiquimod is a novel synthetic agent with immune response modifying activity.

S1439

Tranilast

Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

S8141New

Cl-amidine

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.

S4690New

Escin

Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).

S4706New

Eugenol

Eugenol is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.

S8097New

C-DIM12

C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.

S4169

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.

S2413

Geniposidic acid

Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders.

S1939

(-)-Tetramisole

(-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.

S2910

Tempol

Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.

S3062

Diclofenac Potassium

Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

S4098

Halcinonide

Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.

S1823

Fenoprofen Calcium

Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.

S4152

Ethamsylate

Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.

S4165

Benzydamine HCl

Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.

S2400

Rheic Acid

Rhein (Monorhein; NSC 38629; Rheic acid; Rheinic acid) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities.

S7448

CORM-3

CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.

S3027

Fenoprofen calcium hydrate

Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).

S2350

Rutin

Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.

S1407

Bimatoprost

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

S4529New

Idramantone

Idramantone is an immune agonist.

S1508

Alprostadil

Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.

S1829

Pranlukast

Pranlukast is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.

S7211

PF-04418948

PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1.

Catalog No. Information Product Use Citations Product Validations
A2001New

Ipilimumab

Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.

S2286

Cyclosporin A

Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.

S3032

Bindarit

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

S4753New

Ganoderic acid A

Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.

S8522New

Compstatin

Compstatin binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.

S8291New

Atractylenolide I

Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.

S1514

Cyclosporine

Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.

S7434

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

Catalog No. Information Product Use Citations Product Validations
S1829

Pranlukast

Pranlukast is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.

S7211

PF-04418948

PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1.

Catalog No. Information Product Use Citations Product Validations
S1407

Bimatoprost

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

S4529New

Idramantone

Idramantone is an immune agonist.

S1508

Alprostadil

Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.

Catalog No. Information Product Use Citations Product Validations
S8301New

AS101

AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

S2787

Laquinimod

Laquinimod is a potent immunomodulator. Phase 3.

S7515

VGX-1027

VGX-1027 is an orally active immunomodulator. Phase 1.

S7516

Y-320

Y-320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.

Catalog No. Information Product Use Citations Product Validations
S1211

Imiquimod

Imiquimod is a novel synthetic agent with immune response modifying activity.

S1439

Tranilast

Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

2015, 39(1):114-24

S8141New

Cl-amidine

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively.

S4690New

Escin

Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).

S4706New

Eugenol

Eugenol is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.

S8097New

C-DIM12

C-DIM12 is Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.

S4169

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.

S2413

Geniposidic acid

Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders.

S1939

(-)-Tetramisole

(-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.

S2910

Tempol

Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.

S3062

Diclofenac Potassium

Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

S4098

Halcinonide

Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.

S1823

Fenoprofen Calcium

Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.

S4152

Ethamsylate

Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.

S4165

Benzydamine HCl

Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.

S2400

Rheic Acid

Rhein (Monorhein; NSC 38629; Rheic acid; Rheinic acid) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities.

S7448

CORM-3

CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.

S3027

Fenoprofen calcium hydrate

Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).

S2350

Rutin

Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.