Home » Product Pathways » Apoptosis

Apoptosis Pathway



Apoptosis is the process of programmed cell death. Apoptosis occurs during normal cell turnover, development and in the immune system. Excessive apoptosis will cause atrophy, such as in neurodegenerative diseases, but too little apoptosis results in uncontrolled cell proliferation in cancer. Apoptosis is highly related with caspases, Bcl-2 proteins and granzyme B.

Share
Buy Now / Print Quote

Find Multiple Products by Catalog Number

Continue
Customer's Feedback
Arnaud AUTRET, Trinity College
"I would like to confirm you that everything is perfectly fine with ABT and Obatoclax we got from your company. We confirmed their activity in vitro. We notably observed their impact in an apoptotic model and results are similar to those which have been published."

Dongfeng Chen, The Rausing Lab
"Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future."

Dr. Alexandra Segref, CECAD Cologne,Germay
"I am very satisfied with your product and costumer service. Bortezomib works very well in our assay, it is comparably cheaper than other inhibitors that we tested is more reliable for our assays. We see a great effect by using 10nM concentration."

R.B. Cambridge
"I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more."

Zhenghe John Wang Assistant Professor, Case Western Reserve University
"We have purchased LBH-589, Saha and MS-275 from you and they all worked well."

Jenny Sun
"We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility."

Yu Wang, Harvard University
"The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research."

Philip Seeman, Toronto University
"Your LY404039 compound was well synthesized, its complicated stereochemical structure confirmed by NMR spectroscopy, and was biologically excellent in acting on brain dopamine receptors."

Dung-Fang Lee
"Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells."

Latest Catalog
May 2010
Selleck
Latest
Catalog

Selleck Chemicals Catalog
| Inhibitor | Antibody | siRNA | Protein | Peptide | Cell Signal | © Copyright 2010 Selleck. All Rights Reserved.