Omalizumab (anti-IgE)

Synonyms: Olizumab, rhuMab-E25

Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research.

Omalizumab (anti-IgE)

Click to purchase the isotype control of Omalizumab (anti-IgE)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 10.44 mg/ml Endotoxin Level: <1 EU/mg
99

Choose Selective Immunology & Inflammation related Inhibitors

Biological Activity

Description Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research.
In Vivo
In vivo

Omalizumab (anti-IgE) is effective in controlling the allergic symptoms of allergic rhinitis by lowering inflammatory mediator CysLT levels of nasal lavage in an experimental allergic rhinitis model.[1]

Animal Research Animal models: Sprague Dawley rats
Dosages: 0.5mg
Administration: s.c.

[1]

Product Details

CAS No. 242138-07-4
Isotype Human IgG1
Application Omalizumab (anti-IgE)
Sterility 0.2 μM filtered
Formulation PBS Buffer, PH 7.4
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

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