Dilution Calculator

HomeDilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( )

  • C1
    V1
    C2
    V2

When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

C1=C0/X C1: LOG(C1):
C2=C1/X C2: LOG(C2):
C3=C2/X C3: LOG(C3):
C4=C3/X C4: LOG(C4):
C5=C4/X C5: LOG(C5):
C6=C5/X C6: LOG(C6):
C7=C6/X C7: LOG(C7):
C8=C7/X C8: LOG(C8):

Featured Products

E1051 MRTX1133 MRTX1133 is a highly selective inhibitor of mutant KRAS G12D and can reversibly binds to the activated and inactivated KRAS G12D mutants and inhibit their activity. The specificity of MRTX1133 to KRAS G12D is more than 1000 times that of wild-type KRAS.
E1474 BI-2865 BI-2865 is a none-covalent pan-KRAS Inhibitor. It binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively and inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 ce
E1549 AZD0095 AZD0095 is a selective and orally active Monocarboxylate transporter 4 (MCT4) inhibitor with IC50 of 1.3 nM and effectively inhibits the tumor growth in NCI-H358 xenografts in combination with Cediranib.
E1858 RMC-7977 RMC-7977 is a potent, reversible, tri-complex oral inhibitor that selectively targets active (GTP-bound) forms of KRAS, HRAS, and NRAS, which exhibits broad-spectrum activity against both mutant and wild-type variants (a RASMULTI (ON) inhibitor). It also exhibits significant anti-tumor efficacy in pancreatic ductal adenocarcinoma (PDAC).
E1908 HRO761 HRO761 is a potent, selective, allosteric inhibitor of Werner syndrome RecQ helicase (WRN). It binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation, and demonstrates anti-proliferative effects specifically in microsatellite instability (MSI) cancer cells.
S1067 SB431542 SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.
S1077 SB202190 SB202190 is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis.
S1105 LY294002 LY294002 (SF 1101, NSC 697286) is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. It not only binds to class I PI3Ks and other PI3K-related kinases, but also to novel targets seemingly unrelated to the PI3K family. LY294002 also inhibits CK2 with IC50 of 98 nM. LY294002 is a non-specific DNA-PKcs inhibitor and activates autophagy and apoptosis.
S2619 MG132 MG132 ((S,R,S)-(-)-MG132, Z-Leu-D-Leu-Leu-al) is a potent proteasome (ChTL, TL, and PGPH) inhibitor. MG132 also inhibits calpain (IC50=1.2 μM). MG132 can be used to induce animal models of Parkinson’s disease.
S7085 IWP-2 IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.
S7507 LDN-193189 2HCl LDN-193189 (DM3189) 2HCl is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
S7609 GW4869 GW4869 (GW69A, GW554869A) is a neutral, noncompetitive inhibitor of sphingomyelinase (SMase) with an IC50 of 1 μM. It is selective for N-SMase, and does not inhibit acid SMase at up to at least 150 μM, also is a commonly used exosome inhibitor.
S7692 A-83-01 A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.Solutions are unstable and should be fresh-prepared.
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
S7809 MCC950 Sodium MCC950 Sodium is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes.
S8383 S63845 S63845 is a new, selective MCL-1 inhibitor with the Kd value of 0.19 nM and has no discernible binding to the other BCL-2 members, BCL-2 or BCL-XL.
S8740 A-485 A-485 is a potent, selective and drug-like p300/CBP catalytic inhibitor with an IC50 of 0.06 μM for p300 HAT. It is selective over BET bromodomain proteins and >150 non-epigenetic targets.
S8843 AZD7648 AZD7648 is a potent inhibitor of DNA-PK with an IC50 of 0.6 nM in biochemical assay and more than 100-fold selective against 396 other kinases.
S8874 PLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 < 10 nmol/L), showing > 20-fold selectivity over KIT and FLT3.
S9870 STM2457 STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

New Products Click to View More

F2335 Phospho-PKCθ/PRKCQ (Thr538) Antibody [D2M12] Phospho-PKCθ (Thr538),PKC theta/PRKCQ (phospho T538)
F1062 E2F-1 Antibody [N6L18] E2F 1,E2F1,E2F-1
F3041 Connexin 43 Antibody [F6F11] Connexin 43,Connexin 43 / GJA1,Connexin-43
F3042 PKD/PKCμ Antibody [D22N3] PKC mu/PKD,PKD/PKCμ,PRKD1
F1554 KPNB1 Antibody [K10N6] Importin beta-1,Importin β1,karyopherin β1,KPNB1
F1335 GOPC Antibody [F21D16] GOPC,PIST
F2880 Calnexin (ER Membrane Marker) Antibody [H16B4] Calnexin,Calnexin - ER membrane marker
F3395 SCD1 Antibody [H13N22] SCD1
F3362 KDM1/LSD1 (Nuclear Marker) Antibody [P12K1] KDM1/LSD1,LSD1
F3454 SorLA/SORL1 Antibody [G6C20] SORL1,SorLA/SORL1
F0132 CHOP Antibody [K6F19] CHOP,DDIT3,DDIT3/GADD153/CHOP,GADD153/CHOP
F0785 JMJD2A Antibody [B12L5] JMJD2A,KDM4A / JHDM3A / JMJD2A
F2804 IGF2BP2/IMP-2 Antibody [H6A9] IGF2BP2/IMP-2,IMP2,IMP-2
F3665 Phospho-NEDD4-2 (Ser448) Antibody [D21H23] NEDD4-2 (phospho S448),Phospho-NEDD4L (Ser448)
F0352 Phospho-YAP (Ser127) Antibody [K8E8] Phospho-YAP (Ser127),YAP1 (phospho S127)
F3776 Citrate synthetase Antibody [K19C21] Citrate Synthase,Citrate synthetase
F2876 Phospho-FAK (Tyr397) Antibody [G24K11] FAK (phospho Y397),FAK (Tyr397),p-FAK,Phospho-FAK (Tyr397)
F2692 ATP1A3 Antibody [M10F4] ATP1A3,Sodium Potassium ATPase Alpha 3
F2178 CXCR4 Antibody [G11H20] CXCR4,CXCR-4
F1518 CD56 Antibody [C5A9] CD56,CD56 (NCAM),Neural Cell Adhesion Molecule