96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

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Product Description

Description & Advantages

    • A unique collection of 1835 bioactive chemical compounds for high throughput screening (HTS) and high content screening (HCS)
    • Bioactivity and safety confirmed by preclinical research and clinical trials
    • Some compounds have been approved by the FDA
    • Includes most Selleck inhibitors, APIs, natural products, and chemotherapeutic agents
    • Structurally diverse, medicinally active, and cell permeable
    • Rich documentation with structure, IC50, and customer reviews
    • NMR and HPLC validated to ensure high purity

Product Details

Formulation: A collection of 1835 bioactive chemical compounds supplied as pre-dissolved DMSO solutions
Container: 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Stability:
3 months -20°C in DMSO
6 months -80°C in DMSO
Shipping: Blue ice
Packaging: Inert gas

Bioactive Compound Library Contents

Download the Bioactive Compound Library - SDF Download the Bioactive Compound Library - XLSX

Contents are for reference only and are subject to change without notice.

Customer Reviews (5)

AS-605240 Review
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Rating
Source Saraswati Sukumar of Johns Hopkins University School of Medicine, AS-605240 purchased from Selleck
Method Western blot
Cell Lines T47D cells
Concentrations
Incubation Time 1 h
Results AS-605240 treatment resulted in a reduction of AKT phosphorylation in T47D cells.

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Rating
Source Saraswati Sukumar of Johns Hopkins University School of Medicine., AS-605240 purchased from Selleck
Method Western blot
Cell Lines T47D cells
Concentrations
Incubation Time 1 h
Results AS-605240 treatment resulted in a reduction of AKT phosphorylation in T47D cells.

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Rating
Source AACR, 2011, Cediranib (AZD2171) purchased from Selleck
Method Cell viability assay
Cell Lines Ba/F3 cells
Concentrations 0-1000 nM
Incubation Time 72 h
Results Cediranib inhibited the survival of Ba/F3 cell lines expressing the recombinant TEL/kinase domain fusion protein for FGFR1-4 in a dose-dependent manner.

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Rating
Source J Biomol Screen, 2011, 16, 141-154. Axitinib purchased from Selleck
Method Secondary assay
Cell Lines MDA-MB-231 cells
Concentrations 10 μM
Incubation Time
Results U0126, pF2341066, axitinib, and pKC412 caused significant inhibition of the invasive potential of Mda-Mb-231 spheroids. Conversely, dasatinib, a potent inhibitor of vimentin gene expression, did not significantly alter the invasive potential of MDA-MB-231 spheroids.

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Rating
Source Int J Proteomics, 2011, Article ID 215496. Afatinib (BIBW2992) purchased from Selleck
Method Nikon inverted-phase microscope
Cell Lines lung tumor cell lines
Concentrations 0.1/1 μM
Incubation Time two weeks
Results Reduction of cell colony size formation was observed by the treatment with the irreversible HER1/2 inhibitor BIBW-2992 in H1975 and H1650 cells as seen when these cells were grown in an anchorage-dependent manner.

Product Citations (24)

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Tags: phosphatase inhibitor library