Rhein(Monorhein)

Rhein(Monorhein; NSC 38629; Rheic acid; Rheinic acid) is a constituent of rhubarb which was isolated from the fresh rhizome of Rheum coreanum Nakai.

Catalog No.S2400
Price Stock Quantity  
USD 70 In stock
USD 120 In stock

Free Overnight Delivery on all orders over $ 500.

Order now and get it on

Rhein(Monorhein) Chemical Structure

Rhein(Monorhein) Chemical Structure
Molecular Weight: 284.22

Related Compound Libraries

Rhein(Monorhein) is available in the following compound libraries:

Product Information

Product Description

Biological Activity

Rhein(Monorhein; NSC 38629; Rheic acid; Rheinic acid) is a constituent of rhubarb which was isolated from the fresh rhizome of Rheum coreanum Nakai. The WTK1 cells were treated by rhein of different concentrations (20, 40, 80, 120 μg/ml) and then the comet assay, in vitro micronucleus test and TK gene mutation assay were conducted simultaneously. The solvent control and positive control (mthylmethane sulfonate, MMS) groups were included in the study. Positive results were found at the concentrations of 120 μg/ml and 80 μg/ml of emodin in comet assay and tk gene mutation analysis. High dose of rhein (120 μg/ml) also showed weak mutagenicity in TK gene mutation analysis. In a study, compared with the db/db control group, the fasting glucose concentration was significantly decreased in the rhein treatment group. The first-phase insulin secretory function was impaired significantly in db/db mice, while the first-phase insulin secretory peak was obvious in the rhein treatment mice. Rhein treatment significantly improved glucose tolerance, restored the first-phase insulin secretion and protected the islets function. [1]

Chemical Information

Download Rhein(Monorhein) SDF
Molecular Weight (MW) 284.22
Formula

C15H8O6

CAS No. 478-43-3
Synonyms Monorhein, NSC 38629, Rheic acid, Rheinic acid, Rhubarb yellow
Solubility (25°C)
  • DMSO <1 mg/mL
  • Water <1 mg/mL
  • Ethanol <1 mg/mL
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3Monday–Friday 9:00 AM–5:00 PM (Central Time)

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related Others

  • Cyclocytidine HCl

  • (-)-Epigallocatechin gallate

    (-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.

  • 3-Indolebutyric acid (IBA)

    3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.

  • 4-Methylumbelliferone(4-MU)

    4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.

  • Aesculin (Esculin)

    Aesculin(Esculin) is a glucoside found in horse chestnuts.

  • Amygdalin

    Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.

  • Andrographolide

    Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.

  • Arbutin (Uva, p-Arbutin)

    Arbutin(Uvasol, p-Arbutin) is a tyrosinase inhibitor with an IC50 of 1.09 mM.

  • Artesunate

    Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.

  • Azomycin (2-Nitroimidazole)

    Azomycin(2-Nitroimidazole) is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.

Recently Viewed Items

Tags: buy Rhein(Monorhein) | Rhein(Monorhein) ic50 | Rhein(Monorhein) price | Rhein(Monorhein) cost | Rhein(Monorhein) solubility dmso | Rhein(Monorhein) purchase | Rhein(Monorhein) manufacturer | Rhein(Monorhein) research buy | Rhein(Monorhein) order | Rhein(Monorhein) mouse | Rhein(Monorhein) chemical structure | Rhein(Monorhein) mw | Rhein(Monorhein) molecular weight | Rhein(Monorhein) datasheet | Rhein(Monorhein) supplier | Rhein(Monorhein) in vitro | Rhein(Monorhein) cell line | Rhein(Monorhein) concentration | Rhein(Monorhein) nmr
Contact Us