Vasopressin Receptor

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2116 Conivaptan HCl <1 mg/mL 107 mg/mL 7 mg/mL
S2593 Tolvaptan <1 mg/mL 89 mg/mL 6 mg/mL
S2920 Mozavaptan <1 mg/mL 1 mg/mL 1 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations

Conivaptan HCl

Conivaptan HCl is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia.



Tolvaptan is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.



Mozavaptan is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.