• Vasopressin receptor 1
  • Vasopressin receptor 2

Vasopressin receptor 2 Selective Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2815 Lixivaptan (VPA-985) Lixivaptan (VPA-985, CRTX 080, WAY VPA 985) is an oral, non-peptide, selective V2 receptor vasopressin antagonist with IC50s of 1.2 nM and 2.3 nM for human V2 receptor and rat V2 receptor, respectively. Selective rat V2 receptor, IC50: 2.3 nM; human V2 receptor, IC50: 1.2 nM
S2593 Tolvaptan Tolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia. Selective vasopressin receptor 2, IC50: 3 nM
S2920 Mozavaptan Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively. Selective Vasopressin receptor 2, IC50: 14 nM
S2116 Conivaptan HCl Conivaptan HCl is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia. Pan