Home Epigenetics Histone Acetyltransferase MYST Selective Inhibitors

MYST Selective Inhibitors

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S9805	WM-3835	WM-3835 is a novel and high-specific small molecule Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) inhibitor, able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.	Selective
S8776	WM-1119	WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with IC50 of 0.25 μM. It is 1,100-fold and 250-fold more active against KAT6A than against KAT5 or KAT7, respectively.	Selective	KAT6A, Kd: 0.002 μM; KAT5, Kd: 2.2 μM; KAT7, Kd: 0.5 μM
S6655	WM-8014	WM-8014 is a highly potent inhibitor of histone acetyltransferase KAT6A with an IC50 of 8 nM.	Selective	KAT6A, IC50: 8 nM
S7476	MG149	MG149 (Tip60 HAT inhibitor) is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively.	Selective	Tip60, IC50: 74 μM; MOF, IC50: 47 μM
s7582	Anacardic Acid	Anacardic Acid (6-pentadecylsalicylic Acid) is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.	Pan