MYST Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8776 WM-1119

WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with IC50 of 0.25 μM. It is 1,100-fold and 250-fold more active against KAT6A than against KAT5 or KAT7, respectively.

Selective KAT6A, Kd: 0.002 μM; KAT5, Kd: 2.2 μM; KAT7, Kd: 0.5 μM
S6655 WM-8014

WM-8014 is a highly potent inhibitor of histone acetyltransferase KAT6A with an IC50 of 8 nM.

Selective KAT6A, IC50: 8 nM
S7476 MG149

MG149 (Tip60 HAT inhibitor) is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively.

Selective Tip60, IC50: 74 μM; MOF, IC50: 47 μM
s7582 Anacardic Acid

Anacardic Acid (6-pentadecylsalicylic Acid) is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

Pan