- H1 receptor
- H2 receptor
- H3 receptor
- H4 receptor
H3 receptor Selective Inhibitors | Antagonists
|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype.
|Selective||H3 receptor, Ki: 0.16 nM|
Ciproxifan (FUB 359) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.
|Selective||Histamine H3 receptor, IC50: 9.2 nM|
S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.
|Selective||human H3 receptor, Ki: 1.2 μM; rat H3 receptor, Ki: 8.8 μM; mouse H3 receptor, Ki: 1.44 μM|
Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.
|Selective||Histamine H3 receptor, IC50: 1.9 μM|
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