H3 receptor inhibitor | H3 receptor inhibition

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S5926	Pitolisant hydrochloride	Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype.	Selective	H3 receptor, Ki: 0.16 nM
S2813	Ciproxifan Maleate	Ciproxifan (FUB 359) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.	Selective	Histamine H3 receptor, IC50: 9.2 nM
S8598	S 38093	S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.	Selective	rat H3 receptor, Ki: 8.8 μM; mouse H3 receptor, Ki: 1.44 μM; human H3 receptor, Ki: 1.2 μM
S3176	Betahistine 2HCl	Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.	Selective	Histamine H3 receptor, IC50: 1.9 μM

H3 receptor Selective Inhibitors | Antagonists