- H1 receptor
- H2 receptor
- H3 receptor
- H4 receptor
H3 receptor Selective Inhibitors | Antagonists
| Catalog No. | Product Name | Information | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S5926 | Pitolisant hydrochloride | Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype. |
Selective | H3 receptor, Ki: 0.16 nM |
| S2813 | Ciproxifan Maleate | Ciproxifan (FUB 359) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. |
Selective | Histamine H3 receptor, IC50: 9.2 nM |
| S8598 | S 38093 | S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors. |
Selective | human H3 receptor, Ki: 1.2 μM; rat H3 receptor, Ki: 8.8 μM; mouse H3 receptor, Ki: 1.44 μM |
| S3176 | Betahistine 2HCl | Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM. |
Selective | Histamine H3 receptor, IC50: 1.9 μM |
