• AC
  • EPAC1
  • EPAC2
  • PACAP receptor

AC Selective Inhibitors | Activators

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S4552 Bithionol Bithionol (Actamer) is a potent inhibitor of soluble adenylyl cyclase(sAC) with an IC50 of 4 μM and has antibacterial and anthelmintic properties along with algaecide activity. Selective sAC, IC50: 4.0 μM
S2449 Colforsin (Forskolin, HL 362) Colforsin (Forskolin, HL 362, Coleonol, Colforsin) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy. Selective
S8283 SQ22536 SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. Selective