Sulconazole Nitrate

For research use only. Not for use in humans.

Catalog No.S4120

Sulconazole Nitrate Chemical Structure

Molecular Weight(MW): 460.76

Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 130 In stock
USD 97 In stock
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Biological Activity

Description Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
In vitro

Sulconazole Nitrate possesses a broad spectrum of activity in vitro against dermatophytes, yeasts and some Gram-positive bacteria at concentrations below 5 mg/L in vitro. It has been shown that against representatives of pathogenic yeasts, dermatophytes and Aspergilli, the RIF values of sulconazole are broadly similar to those of other imidazoles. The fungicidal potency of sulconazole in vitro depends on its concentration and on the growth phase of the inoculum cells. Sulconazole has also demonstrated antibacterial activity in vitro, with MIC values below 12.5 mg/L. [1]

In vivo The efficacy and safety of sulconazole 1% cream has been demonstrated in controlled clinical studies in patients with superficial dermatophyte or yeast infections. To minimise the risk of reinfection treatment should continue for 3 weeks in Candida infections, tinea cruris, tinea corporis and pityriasis versicolor, and for 4 weeks in patients with tinea pedis. [1]

Protocol

Solubility (25°C)

In vitro DMSO 92 mg/mL (199.67 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 460.76
Formula

C18H15Cl3N2S.HNO3

CAS No. 61318-91-0
Storage powder
in solvent
Synonyms N/A
Smiles O[N+]([O-])=O.ClC1=CC=C(CSC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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The Serial Dilution Calculator Equation

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID