| S7418 |
Cycloheximide
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Cycloheximide, an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.Cycloheximide (NSC-185) can be used to induce animal models of Dysmnesia.Solutions are unstable and should be fresh-prepared.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
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Cancer Cell, 2025, S1535-6108(25)00070-4
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Signal Transduct Target Ther, 2025, 10(1):81
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Signal Transduct Target Ther, 2025, 10(1):26
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| S3073 |
Caspofungin (MK-0991) Acetate
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Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.
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Nat Commun, 2025, 16(1):9125
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PLoS Pathog, 2025, 21(5):e1013220
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PLoS Pathog, 2024, 20(9):e1012521
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| S4286 |
Anidulafungin
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Anidulafungin, an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.
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Viruses, 2023, 15(2)452
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BMC Med, 2022, 20(1):359
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Antiviral Res, 2021, S0166-3542(21)00178-9
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| S4287 |
Micafungin Sodium
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Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
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Microbiol Spectr, 2024, e0352623.
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BMC Med, 2022, 20(1):359
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Antiviral Res, 2021, S0166-3542(21)00178-9
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| S2058 |
Tolnaftate
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Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
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iScience, 2024, 27(10):110862
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J Pers Med, 2022, 12(2)258
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Hum Cell, 2022, 10.1007/s13577-022-00671-y
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| S1725 |
Terbinafine
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Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
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Front Oncol, 2023, 13:1111570
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Neurooncol Adv, 2022, 4(1):vdac018
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J Cell Mol Med, 2020, 25
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| S1956 |
Miconazole Nitrate
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Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.
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Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
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Chem Biol Interact, 2021, 343:109498
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Biomol Ther (Seoul), 2020, 25
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| S3079 |
Atovaquone
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Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
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Breast Cancer Res, 2025, 27(1):136
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Antimicrob Agents Chemother, 2025, e0047125.
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Int J Parasitol Drugs Drug Resist, 2025, 29:100626
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| S2557 |
Terbinafine HCl
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Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
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Cell Rep Med, 2023, S2666-3791(22)00494-3
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Oncogene, 2021, 10.1038/s41388-021-01934-y
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J Cell Mol Med, 2020, 25
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| S2536 |
Miconazole
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Miconazole (Monistat,R18134) is an imidazole antifungal agent.
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Nat Commun, 2024, 15(1):3068
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Int J Mol Sci, 2022, 23(22)13809
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Chem Biol Interact, 2021, 343:109498
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