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Catalog No. Product Name Information Product Use Citations Product Validations
S0491 Manogepix (E1210) Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.
S0770 Camalexin Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S0832 Dimboa Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.
S0917 Allosecurinin Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S0938 Sakuranetin Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
S0971 Kakuol Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.
S1331 Fluconazole (UK 49858) Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.
Microbiol Spectr, 2022, 10(1):e0200721
Front Microbiol, 2021, 12:761113
Front Microbiol, 2021, 12:649026
S1517 Natamycin Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference
Expert Opin Drug Deliv, 2020, 17(3):407-421
BMC Microbiol, 2020, 20(1):275
S1606 Clotrimazole Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
J Cell Physiol, 2020, 10.1002
J Biol Chem, 2018, 293(1):333-344
S1666 Flucytosine Flucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
Sci Adv, 2021, 7(27)eabh3032
S1676 Amorolfine HCl Amorolfine HCl is an antifungal reagent.
Nat Commun, 2021, 12(1):652
Cell Chem Biol, 2019, 26(4):593-599
Nature, 2018, 560(7718):372-376
S1725 Terbinafine Terbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
J Cell Mol Med, 2020, 25
Arch Dermatol Res, 2020, 312(5):337-352
Eur J Pharm Sci, 2019, 136:104945
S1833 Butoconazole nitrate Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S1854 Bifonazole Bifonazole (Bay h 4502) is a substituted imidazole antifungal agent.
Nature, 2018, 560(7718):372-376
S1910 Tioconazole Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.
J Mol Cell Biol, 2021, mjab059
Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S1934 Nystatin (Fungicidin) Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.
Nature, 2022, 603(7899):159-165
Viruses, 2022, 14(3)496
J Colloid Interface Sci, 2021, 601:650-660
S1956 Miconazole Nitrate Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
Chem Biol Interact, 2021, 343:109498
Biomol Ther (Seoul), 2020, 25
S1997 Liranaftate Liranaftate (M-732) is a squalene epoxidase inhibitor with anti-fungicidal activities.
S2031 Fenticonazole Nitrate Fenticonazole Nitrate is an azole antifungal agent.
S2058 Tolnaftate Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 34(6):1911-1918
Hum Cell, 2021, 10.1007/s13577-021-00639-4
S2321 Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.
Reprod Biol, 2021, 21(4):100567
Neoplasia, 2020, 22(11):576-589
J Chromatogr A, 2020, 1625:461230
S2476 Itraconazole (R 51211) Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.
Microbiol Spectr, 2022, 10(1):e0200721
BMC Microbiol, 2022, 22(1):21
Hum Cell, 2022, 10.1007/s13577-022-00671-y
S2528 Ciclopirox Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.
Cell Death Dis, 2021, 12(12):1141
Int J Mol Sci, 2021, 22(15)8299
J Transl Med, 2021, 19(1):347
S2534 Isoconazole nitrate Isoconazole nitrate (Travogen) is an azole antifungal reagent.
S2535 Econazole nitrate Econazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.
Biomol Ther (Seoul), 2020, 25
S2536 Miconazole Miconazole (Monistat) is an imidazole antifungal agent.
Chem Biol Interact, 2021, 343:109498
Drug Test Anal, 2020, 10.1002/dta.2917
Biomol Ther (Seoul), 2020, 25
S2557 Terbinafine HCl Terbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
Oncogene, 2021, 10.1038/s41388-021-01934-y
Hum Mol Genet, 2020, ddaa244
J Cell Mol Med, 2020, 25
S3019 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.
Front Cell Dev Biol, 2021, 9:719187
ACS Omega, 2021, 6(12):8477-8487
bioRxiv, 2019, 10.1101/748129
S3073 Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.
Comput Struct Biotechnol J, 2022, 20:1077-1087
Antiviral Res, 2021, S0166-3542(21)00178-9
Pharmaceuticals (Basel), 2021, 14(4)338
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
J Cell Biochem, 2022, 10.1002/jcb.30213
Sci Rep, 2019, 9(1):536
Sci Transl Med, 2015, 7(290):290ra89
S3154 Butenafine HCl Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156 Naftifine HCl Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
S3161 Sertaconazole nitrate Sertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
S3307 Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S3373 Deoxylapachol

Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.

S3532 AN-2718 AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595 D-Gluconic acid D-Gluconic acid is an antifungal agent.
S3646 Thimerosal Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.
Cell Chem Biol, 2021, S2451-9456(21)00442-6
S3676 Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S3705 Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S3722 Isavuconazole Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S3829 Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.
S3860 Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S3910 4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S3966 Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3979 Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S3985 Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S3990 Trans-Anethole Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
S4075 Zinc Pyrithione Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Biol Reprod, 2019, 100(2):468-478
Cell Syst, 2017, 4(6-:600-610
S4120 Sulconazole Nitrate Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
Sci Adv, 2021, 7(36):eabf6033
S4178 Climbazole Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.
S4187 Salicylanilide Salicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.
Hum Mol Genet, 2020, ddaa244
S4258 Luliconazole Luliconazole is a broad-spectrum antifungal drug.
S4286 Anidulafungin (LY303366) Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.
Antiviral Res, 2021, S0166-3542(21)00178-9
Pharmaceuticals (Basel), 2021, 14(4)338
Emerg Microbes Infect, 2020, 1-53
S4287 Micafungin (FK 463) Sodium Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
Microbiol Spectr, 2021, 9(3):e0139521
Antiviral Res, 2021, S0166-3542(21)00178-9
Bioorg Med Chem, 2021, 44:116293
S4516 (+)-Camphor Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S4525 Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4559 Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S4581 Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S4584 Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.
Environ Toxicol, 2018, 33(4):436-445
S4601 Clioquinol Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
Mol Oncol, 2021, 10.1002/1878-0261.13079
FASEB J, 2019, 10.1096/fj.201802603RR
S4755 lanosterol Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.
S4793 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S4806 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
S4843 Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S4878 Neticonazole Hydrochloride Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S4970 Nerol Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
S4996 Tavaborole (AN-2690) Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5025 Efinaconazole Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S5033 Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.
bioRxiv, 2020, 2020/9/20.4.7.30734
S5080 Neticonazole Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S5213 Piroctone Olamine Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5271 Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
S5359 Butoconazole Butoconazole is an imidazole antifungal used in gynecology.
Nature, 2018, 560(7718):372-376
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
Eur J Pharmacol, 2020, 876:173064
S5512 Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.
Nat Commun, 2019, 10(1):4013
S5541 Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S5553 Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5704 Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S5724 Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829 Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S5845 Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S5944 Butenafine Butenafine is a synthetic benzylamine antifungal agent.
S6118 Terpinen-4-ol Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S6270 2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S6408 Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S6451 Salifungin Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S6467 Fosfluconazole Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S7418New Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.
Nat Commun, 2022, 13(1):1444
Nat Commun, 2022, 13(1):894
Redox Biol, 2022, 52:102292
S8095 Tubercidin Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.
Mol Cell, 2020, 80(6):1104-1122.e9
S9057 Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
J Invest Dermatol, 2018, 138(12):2644-2652
S9072 Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S9350 Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9413 Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S9444 Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S1442 Voriconazole (UK-109496) Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.
Microbiol Spectr, 2022, 10(1):e0200721
BMC Microbiol, 2022, 22(1):21
Front Microbiol, 2021, 12:649026
S5083 Lentinan Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.
S5174 Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
Int J Mol Sci, 2017, 18(9)
S0491 Manogepix (E1210) Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.
S0770 Camalexin Camalexin, a phytoalexin isolated from Camelina sativa and Arabidopsis (Cruciferae), can induce reactive oxygen species (ROS) production. Camalexin has antibacterial, antifungal, antiproliferative and anticancer activities.
S0832 Dimboa Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal agent used in crops.
S0917 Allosecurinin Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from M.indica and M.discoidea with antifungal activity.
S0938 Sakuranetin Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
S0971 Kakuol Kakuol is a natural compound extracted from the rhizomes of Asarum sieboldii with antifungal activity.
S1331 Fluconazole (UK 49858) Fluconazole (UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.
Microbiol Spectr, 2022, 10(1):e0200721
Front Microbiol, 2021, 12:761113
Front Microbiol, 2021, 12:649026
S1517 Natamycin Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference
Expert Opin Drug Deliv, 2020, 17(3):407-421
BMC Microbiol, 2020, 20(1):275
S1606 Clotrimazole Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
J Cell Physiol, 2020, 10.1002
J Biol Chem, 2018, 293(1):333-344
S1666 Flucytosine Flucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
Sci Adv, 2021, 7(27)eabh3032
S1676 Amorolfine HCl Amorolfine HCl is an antifungal reagent.
Nat Commun, 2021, 12(1):652
Cell Chem Biol, 2019, 26(4):593-599
Nature, 2018, 560(7718):372-376
S1725 Terbinafine Terbinafine (SF 86-327) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
J Cell Mol Med, 2020, 25
Arch Dermatol Res, 2020, 312(5):337-352
Eur J Pharm Sci, 2019, 136:104945
S1833 Butoconazole nitrate Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
S1854 Bifonazole Bifonazole (Bay h 4502) is a substituted imidazole antifungal agent.
Nature, 2018, 560(7718):372-376
S1910 Tioconazole Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.
J Mol Cell Biol, 2021, mjab059
Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S1934 Nystatin (Fungicidin) Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.
Nature, 2022, 603(7899):159-165
Viruses, 2022, 14(3)496
J Colloid Interface Sci, 2021, 601:650-660
S1956 Miconazole Nitrate Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
Chem Biol Interact, 2021, 343:109498
Biomol Ther (Seoul), 2020, 25
S1997 Liranaftate Liranaftate (M-732) is a squalene epoxidase inhibitor with anti-fungicidal activities.
S2031 Fenticonazole Nitrate Fenticonazole Nitrate is an azole antifungal agent.
S2058 Tolnaftate Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 34(6):1911-1918
Hum Cell, 2021, 10.1007/s13577-021-00639-4
S2321 Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.
Reprod Biol, 2021, 21(4):100567
Neoplasia, 2020, 22(11):576-589
J Chromatogr A, 2020, 1625:461230
S2476 Itraconazole (R 51211) Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.
Microbiol Spectr, 2022, 10(1):e0200721
BMC Microbiol, 2022, 22(1):21
Hum Cell, 2022, 10.1007/s13577-022-00671-y
S2528 Ciclopirox Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.
Cell Death Dis, 2021, 12(12):1141
Int J Mol Sci, 2021, 22(15)8299
J Transl Med, 2021, 19(1):347
S2534 Isoconazole nitrate Isoconazole nitrate (Travogen) is an azole antifungal reagent.
S2535 Econazole nitrate Econazole Nitrate (NSC 243115) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.
Biomol Ther (Seoul), 2020, 25
S2536 Miconazole Miconazole (Monistat) is an imidazole antifungal agent.
Chem Biol Interact, 2021, 343:109498
Drug Test Anal, 2020, 10.1002/dta.2917
Biomol Ther (Seoul), 2020, 25
S2557 Terbinafine HCl Terbinafine HCl (KWD 201) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
Oncogene, 2021, 10.1038/s41388-021-01934-y
Hum Mol Genet, 2020, ddaa244
J Cell Mol Med, 2020, 25
S3019 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.
Front Cell Dev Biol, 2021, 9:719187
ACS Omega, 2021, 6(12):8477-8487
bioRxiv, 2019, 10.1101/748129
S3073 Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.
Comput Struct Biotechnol J, 2022, 20:1077-1087
Antiviral Res, 2021, S0166-3542(21)00178-9
Pharmaceuticals (Basel), 2021, 14(4)338
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
J Cell Biochem, 2022, 10.1002/jcb.30213
Sci Rep, 2019, 9(1):536
Sci Transl Med, 2015, 7(290):290ra89
S3154 Butenafine HCl Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
S3156 Naftifine HCl Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
S3161 Sertaconazole nitrate Sertaconazole nitrate (FI-7045) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
S3307 Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin), isolated from Lychnophora markgravii aerial parts, shows strong antibacterial and antifungal effects.
S3373 Deoxylapachol

Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia with antifungal and anti-cancer activity.

S3532 AN-2718 AN-2718, an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.
S3595 D-Gluconic acid D-Gluconic acid is an antifungal agent.
S3646 Thimerosal Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.
Cell Chem Biol, 2021, S2451-9456(21)00442-6
S3676 Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S3705 Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
S3722 Isavuconazole Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S3829 Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.
S3860 Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S3910 4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S3966 Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3979 Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S3985 Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
S3990 Trans-Anethole Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
S4075 Zinc Pyrithione Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Biol Reprod, 2019, 100(2):468-478
Cell Syst, 2017, 4(6-:600-610
S4120 Sulconazole Nitrate Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
Sci Adv, 2021, 7(36):eabf6033
S4178 Climbazole Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.
S4187 Salicylanilide Salicylanilides (WR10019) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.
Hum Mol Genet, 2020, ddaa244
S4258 Luliconazole Luliconazole is a broad-spectrum antifungal drug.
S4286 Anidulafungin (LY303366) Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.
Antiviral Res, 2021, S0166-3542(21)00178-9
Pharmaceuticals (Basel), 2021, 14(4)338
Emerg Microbes Infect, 2020, 1-53
S4287 Micafungin (FK 463) Sodium Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
Microbiol Spectr, 2021, 9(3):e0139521
Antiviral Res, 2021, S0166-3542(21)00178-9
Bioorg Med Chem, 2021, 44:116293
S4516 (+)-Camphor Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1 and TRPV3.
S4525 Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4559 Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.
S4581 Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S4584 Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.
Environ Toxicol, 2018, 33(4):436-445
S4601 Clioquinol Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
Mol Oncol, 2021, 10.1002/1878-0261.13079
FASEB J, 2019, 10.1096/fj.201802603RR
S4755 lanosterol Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol.
S4793 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S4806 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
S4843 Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S4878 Neticonazole Hydrochloride Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
S4970 Nerol Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
S4996 Tavaborole (AN-2690) Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S5025 Efinaconazole Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S5033 Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.
bioRxiv, 2020, 2020/9/20.4.7.30734
S5080 Neticonazole Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S5213 Piroctone Olamine Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5271 Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
S5359 Butoconazole Butoconazole is an imidazole antifungal used in gynecology.
Nature, 2018, 560(7718):372-376
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
Eur J Pharmacol, 2020, 876:173064
S5512 Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.
Nat Commun, 2019, 10(1):4013
S5541 Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S5553 Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5704 Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S5724 Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829 Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.
S5845 Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones with antibacterial, antifungal, antitumor and anti-inflammatory properties.
S5944 Butenafine Butenafine is a synthetic benzylamine antifungal agent.
S6118 Terpinen-4-ol Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
S6270 2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH) is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
S6408 Hexetidine Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.
S6451 Salifungin Salifungin (Multifungin, Bromosalicylchloranilide) is an antifungal and may cause allergic contact dermatitis in some individuals.
S6467 Fosfluconazole Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S7418New Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.
Nat Commun, 2022, 13(1):1444
Nat Commun, 2022, 13(1):894
Redox Biol, 2022, 52:102292
S8095 Tubercidin Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.
Mol Cell, 2020, 80(6):1104-1122.e9
S9057 Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
J Invest Dermatol, 2018, 138(12):2644-2652
S9072 Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S9350 Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9413 Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S9444 Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S7418New Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.
Nat Commun, 2022, 13(1):1444
Nat Commun, 2022, 13(1):894
Redox Biol, 2022, 52:102292