Ropivacaine HCl

For research use only.

Catalog No.S4058 Synonyms: LEA-103 HCl

1 publication

Ropivacaine HCl Chemical Structure

CAS No. 132112-35-7

Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 163 In stock
USD 122 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Selleck's Ropivacaine HCl has been cited by 1 publication

Purity & Quality Control

Choose Selective Sodium Channel Inhibitors

Biological Activity

Description Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
In vitro

Ropivacaine HCl is a local anaesthetic agent. Ropivacaine HCl elicits nerve block via reversible inhibition of sodium ion influx in nerve fibres. The pKa of ropivacaine HCl is ~8.2. Ropivacaine HCl has the potential to induce cardiovascular toxicity and CNS toxicity at high plasma concentrations. [1]


Solubility (25°C)

In vitro DMSO 62 mg/mL (199.44 mM)
Water 46 mg/mL (147.97 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 310.86


CAS No. 132112-35-7
Storage powder
in solvent
Synonyms LEA-103 HCl

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04570878 Not yet recruiting Procedure: SC TAP|Procedure: Control Congenital Heart Disease Seoul National University Hospital January 1 2021 Not Applicable
NCT04298099 Recruiting Drug: Ropivacaine Anesthesia Local Baylor College of Medicine December 17 2020 Phase 4
NCT04257682 Not yet recruiting Drug: Bupivacaine|Drug: Ropivacaine|Drug: Mepivacaine Knee Osteoarthritis|Hip Osteoarthritis Ottawa Hospital Research Institute September 2020 Phase 4
NCT04327063 Recruiting Drug: Saline|Drug: Ropivacaine Malignant Neoplasm of Breast Institut Curie August 4 2020 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Sodium Channel Signaling Pathway Map

Related Sodium Channel Products

Tags: buy Ropivacaine HCl | Ropivacaine HCl supplier | purchase Ropivacaine HCl | Ropivacaine HCl cost | Ropivacaine HCl manufacturer | order Ropivacaine HCl | Ropivacaine HCl distributor
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID