Ropivacaine HCl

Catalog No.S4058 Synonyms: LEA-103 HCl

Ropivacaine HCl Chemical Structure

Molecular Weight(MW): 310.86

Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.

Size Price Stock Quantity  
In DMSO USD 130 In stock
USD 97 In stock
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Biological Activity

Description Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
In vitro

Ropivacaine HCl is a local anaesthetic agent. Ropivacaine HCl elicits nerve block via reversible inhibition of sodium ion influx in nerve fibres. The pKa of ropivacaine HCl is ~8.2. Ropivacaine HCl has the potential to induce cardiovascular toxicity and CNS toxicity at high plasma concentrations. [1]

Protocol

Solubility (25°C)

In vitro DMSO 62 mg/mL (199.44 mM)
Water 46 mg/mL (147.97 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 310.86
Formula

C17H26N2O.HCl

CAS No. 132112-35-7
Storage powder
in solvent
Synonyms LEA-103 HCl

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03666845 Recruiting Procedure: Sciatic nerve block Regional Anesthesia Morbidity|Local Anesthetic Drug Adverse Reaction Seoul National University Hospital October 1 2019 --
NCT03476642 Not yet recruiting Drug: Ropivacaine|Drug: Epinephrine Distribution of Ropivacaine in Erector Spinae Plane Block Milton S. Hershey Medical Center September 2019 Phase 4
NCT04081922 Not yet recruiting Procedure: Erector spinae plane block Pectus Excavatum Seoul National University Hospital September 30 2019 Not Applicable

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID