# Promethazine HCl

For research use only.

Catalog No.S4293

3 publications

CAS No. 58-33-3

Promethazine HCl is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.

Size Price Stock Quantity
 50mg GBP 79 In stock 0 1 2 3 4 5 6 7 8 9 10 200mg GBP 161 In stock 0 1 2 3 4 5 6 7 8 9 10 Bulk Size Bulk Discount

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### Biological Activity

Description Promethazine HCl is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.

### Solubility (25°C)

 In vitro DMSO 64 mg/mL (199.45 mM) Water 64 mg/mL (199.45 mM) Ethanol 34 mg/mL (105.95 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Molecular Weight 320.88 C17H21ClN2S 58-33-3 3 years-20°C powder 2 years-80°C in solvent N/A CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl

### In vivo Formulation Calculator (Clear solution)

 Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment) Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.) % DMSO+ % PEG300 Corn oil + % Tween 80+ % ddH2O CalculateReset

### Bio Calculators

Molarity Calculator

## Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

### Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

• Mass
Concentration
Volume
Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

## Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

### Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

• C1
V1
C2
V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

## The Serial Dilution Calculator Equation

• ### Computed Result

• C1=C0/X C2=C1/X C1: LOG(C1): C2: LOG(C2): C3: LOG(C3): C4: LOG(C4): C5: LOG(C5): C6: LOG(C6): C7: LOG(C7): C8: LOG(C8):
Molecular Weight Calculator

## Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

### Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

#### Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

#### Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

#### Molarity Calculator

 Mass Concentration Volume Molecular Weight pg ng μg mg g kg = fM pM nM μM mM M × nL μL mL L ×

### Clinical Trial Information(data from https://clinicaltrials.gov, updated on 2021-05-17)

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04805073 Not yet recruiting Drug: Promethazine|Drug: Placebo Pruritus|Pregnancy Related University of Florida June 2021 Phase 4
NCT03539562 Completed Drug: Morphine Sulfate and Promethazine Labor Pain|Early Labor University of California San Francisco September 27 2017 --
NCT02465866 Completed Drug: CL-108|Drug: Vicoprofen|Drug: Ultracet|Drug: Phenergan Healthy Charleston Laboratories Inc November 2014 Phase 1
NCT01644838 Completed Drug: Hyoscine|Drug: Promethazine Labor Pain Mashhad University of Medical Sciences August 2010 Phase 2|Phase 3

### Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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