For research use only.

Catalog No.S3151 Synonyms: Glurenorm

2 publications

Gliquidone Chemical Structure

Molecular Weight(MW): 527.63

Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.

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10mM (1mL in DMSO) USD 113 In stock
USD 122 In stock
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Biological Activity

Description Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.
Potassium channel [1]
27.2 nM
In vivo Gliquidone (0.1–1.0 μg per mouse i.c.v.) prevents antinociception produced by amitriptyline and clomipramine in a dose-dependent manner in male swiss albino mice. [2] Gliquidone (0.06–16 μg per mouse, i.c.v.) antagonizes the antinociception induced by buprenorphine, morphine and methadone. [3] Gliquidone (6 μg per mouse, i.c.v.) prevents the antinociception induced by clonidine (0.125 mg/kg, s.c.) and guanabenz (0.30 mg/kg, s.c.), while a lower dose of gliquidone (3 μg per mouse, i.c.v.) is ineffective. [4] Glurenorm (10 mg/kg) given to the diabetic rats produces significant reductions in blood glucose, nonenzymatic glycosylation, and total protein in the lenses, and significantly increases in glutathione levels in the lenses. [5]


Solubility (25°C)

In vitro DMSO 105 mg/mL (199.0 mM)
Ethanol 6 mg/mL (11.37 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+corn oil
For best results, use promptly after mixing.

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 527.63


CAS No. 33342-05-1
Storage powder
in solvent
Synonyms Glurenorm
Smiles CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C

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