MT Receptor

Choose Selective MT Receptor Inhibitors

MT Receptor Signaling Pathway Map

MT Receptor Signaling Pathways
Isoform-selective Inhibitors

MT Receptor Products

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  • MT Receptor Antagonist (1)
  • MT Receptor Agonists (3)
  • New MT Receptor Products
Catalog No. Product Name Information Product Use Citations Product Validations
S3584 Luzindole Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.
Aging Cell, 2021, e13375
Int Immunopharmacol, 2021, 96:107787
S1204 Melatonin (NSC 113928) Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.
Ecotoxicol Environ Saf, 2022, 241:113754
Cell Chem Biol, 2021, S2451-9456(21)00442-6
Int J Mol Sci, 2021, 22(11)5649
S1259 Ramelteon Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.
Aging Cell, 2021, e13375
Cell Cycle, 2021, 20(12):1195-1208
Plant Cell Physiol, 2020, 10.1093/pcp/pcaa018
S4281 Tasimelteon Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).
S3584 Luzindole Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.
Aging Cell, 2021, e13375
Int Immunopharmacol, 2021, 96:107787
S1204 Melatonin (NSC 113928) Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.
Ecotoxicol Environ Saf, 2022, 241:113754
Cell Chem Biol, 2021, S2451-9456(21)00442-6
Int J Mol Sci, 2021, 22(11)5649
S1259 Ramelteon Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.
Aging Cell, 2021, e13375
Cell Cycle, 2021, 20(12):1195-1208
Plant Cell Physiol, 2020, 10.1093/pcp/pcaa018
S4281 Tasimelteon Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).
Tags: MT Receptor inhibitor|MT Receptor agonist|MT Receptor activator|MT Receptor inducer|MT Receptor antagonist|MT Receptor signaling pathway|MT Receptor assay kit