PKM

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S8616 PKM2 inhibitor(compound 3k) <1 mg/mL 6 mg/mL <1 mg/mL
S7302 TEPP-46 (ML265, CID-44246499, NCGC00186528) <1 mg/mL 74 mg/mL <1 mg/mL
S7928 DASA-58 <1 mg/mL 91 mg/mL <1 mg/mL
S5545 DL-Serine 8 mg/mL <1 mg/mL -1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8616

PKM2 inhibitor(compound 3k)

PKM2 inhibitor(Compound 3K) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.

S7302New

TEPP-46 (ML265, CID-44246499, NCGC00186528)

ML265 is a potent activator of PKM2 in both biochemical (AC50 = 92 nM) and cell-based assays with high selectivity over PKM1, PKR and PKL.

S7928

DASA-58

DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.

S5545New

DL-Serine

Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.

Tags: PKM activator | PKM inhibitor | PKM modulator |PKM activity