- Inhibitory Selectivity
- PKM Inhibitors (4)
- New PKM Products
|Catalog No.||Information||Product Use Citations||Product Validations|
PKM2 inhibitor(Compound 3K) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.
ML265 is a potent activator of PKM2 in both biochemical (AC50 = 92 nM) and cell-based assays with high selectivity over PKM1, PKR and PKL.
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.