Home Metabolism Peroxidases GPX Selective Inhibitors

GPX Selective Inhibitors

  • GPX
  • MPO
  • HRP
  • TPO
  • CCP
  • Hydroperoxidase
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S0788 ML 210 ML-210 (CID 49766530) is a selective covalent inhibitor of cellular glutathione peroxidase 4 (GPX4) with EC50 of 0.04 μM and induces ferroptosis. ML-210 can selectively kill cells induced to express mutant RAS. ML-210 exhibits anti-cancer activity. Selective GPX4, EC50: 0.04 μM
S8155 RSL3 RSL3 ((1S,3R)-RSL3) is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Selective