ERK1 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7554 GDC-0994

GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.

Pan ERK1, IC50: 1.1 nM
S7101 SCH772984

SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.

Pan ERK1, IC50: 4 nM
s7524 FR 180204

FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively.

Pan ERK1, Ki: 0.31 μM