Home Cytoskeletal Signaling Dynamin Dynamin-I Selective Inhibitors

Dynamin-I Selective Inhibitors

  • Dynamin I
  • Dynamin II
  • drp1
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S5422 Trimethyloctadecylammonium bromide Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ. Selective Dynamin I, IC50: 1.9 μM
S7162 Mdivi-1 Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis. Selective Dnm1 GTPase, IC50: 1 μM-10 μM
S7163 Dyngo-4a Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively. Pan DynI (brain), IC50: 0.38 μM; DynI (rec), IC50: 1.1 μM