Dynamin

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Dynamin Products

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  • Dynamin Inhibitors (6)
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Catalog No. Product Name Information Product Use Citations Product Validations
E1081New MiTMAB

MiTMAB is a selective dynamin inhibitor that targets the dynamin-phospholipid interaction. MiTMAB inhibits dynamin GTPase activity with a Ki of 940 nM.

S5422 Trimethyloctadecylammonium bromide Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ.
S7162 Mdivi-1 Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
Cell Rep, 2022, 39(2):110635
Exp Mol Med, 2022, 10.1038/s12276-022-00745-9
Front Immunol, 2022, 13:827004
S7163 Dyngo-4a Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
Nature, 2022, 603(7899):159-165
Theranostics, 2022, 12(3):1148-1160
Explor Target Antitumor Ther, 2022, 3:37-49
S8047 Dynasore Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).
Nature, 2022, 603(7899):159-165
J Neuroinflammation, 2022, 19(1):53
PLoS Pathog, 2022, 18(6):e1010620
S9887 P110 P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.
E1081New MiTMAB

MiTMAB is a selective dynamin inhibitor that targets the dynamin-phospholipid interaction. MiTMAB inhibits dynamin GTPase activity with a Ki of 940 nM.

S5422 Trimethyloctadecylammonium bromide Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ.
S7162 Mdivi-1 Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
Cell Rep, 2022, 39(2):110635
Exp Mol Med, 2022, 10.1038/s12276-022-00745-9
Front Immunol, 2022, 13:827004
S7163 Dyngo-4a Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
Nature, 2022, 603(7899):159-165
Theranostics, 2022, 12(3):1148-1160
Explor Target Antitumor Ther, 2022, 3:37-49
S8047 Dynasore Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).
Nature, 2022, 603(7899):159-165
J Neuroinflammation, 2022, 19(1):53
PLoS Pathog, 2022, 18(6):e1010620
S9887 P110 P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.
E1081New MiTMAB

MiTMAB is a selective dynamin inhibitor that targets the dynamin-phospholipid interaction. MiTMAB inhibits dynamin GTPase activity with a Ki of 940 nM.

Tags: Dynamin inhibitor|Dynamin agonist|Dynamin activator|Dynamin inducer|Dynamin antagonist|Dynamin signaling pathway|Dynamin assay kit