PF-562271

Catalog No.S2890

PF-562271 Chemical Structure

Molecular Weight(MW): 507.49

PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

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In DMSO USD 350 In stock
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USD 270 In stock
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Cited by 37 Publications

Purity & Quality Control

Choose Selective FAK Inhibitors

Biological Activity

Description PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Targets
FAK [1]
(Cell-free assay)
PYK2 [1]
(Cell-free assay)
CDK2/CyclinE [1]
(Cell-free assay)
CDK3/CyclinE [1]
(Cell-free assay)
CDK1/CyclinB [1]
(Cell-free assay)
1.5 nM 13 nM 30 nM 47 nM 58 nM
In vitro

PF-562271 binds in the ATP-binding cleft of FAK, forming two of the three “canonical” H-bonds between the inhibitor and main-chain atoms in the kinase hinge region. PF-562271 is potent in an inducible cell-based assay measuring phospho-FAK with IC50 of 5 nM. PF-562271 (3.3 μM) results in G1 arrest of PC3-M cells. [1] PF-562271 (1 nM) blocks bFGF-stimulated blood vessel angiogenesis as performed in chicken chorioallantoic membrane assays. PF-262271 potently blocks blood vessel sprouting without detectable changes in vascular leakage. [2] PF-562271 (250 nM) results in complete inhibition of collective A431 cell invasion into collagen gels. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
MV-4-11 NXvTXok1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1WwWWlEPTB;MD6yO|Y3KM7:TR?= MmXvV2FPT0WU
SW982 M4P2WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTBwM{K4NkDPxE1? MkiwV2FPT0WU
KM12 NVvsdXE3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTBwM{i1OVch|ryP NF;BbnBUSU6JRWK=
COLO-205 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml20TWM2OD1yLkS4OlU5KM7:TR?= MVXTRW5ITVJ?
COLO-829 M2G0V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk\DTWM2OD1yLke1NVc3KM7:TR?= MWPTRW5ITVJ?
MG-63 M3rrd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjGdpRKSzVyPUCuPFA3OzdizszN MXPTRW5ITVJ?
IGROV-1 Mn3sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmW4TWM2OD1yLkixNFM5KM7:TR?= NYDwdYdqW0GQR1XS
NCI-H650 M1KzOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYjjTJJzUUN3ME2wMlg{OTV2IN88US=> NH31Z2tUSU6JRWK=
RT-112 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3Ptd2lEPTB;MD65PFQ3KM7:TR?= MWHTRW5ITVJ?
BCPAP MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF:xO4hKSzVyPUGuNFEzQDhizszN NGHLRm1USU6JRWK=
ALL-PO M17tS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjoWGhKSzVyPUGuNFE2QDRizszN NHHCNVNUSU6JRWK=
KYSE-270 M4\FUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGe5fZhKSzVyPUGuNFQ4OTRizszN MVjTRW5ITVJ?
8305C MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTFwMEm5NFQh|ryP MmnrV2FPT0WU
NCI-H810 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrRTWM2OD1zLkGwO|c3KM7:TR?= MW\TRW5ITVJ?
CAL-33 MkHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPtTWM2OD1zLkGyPVM5KM7:TR?= M2O0W3NCVkeHUh?=
AN3-CA MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTFwMkG4Olch|ryP M1TjOnNCVkeHUh?=
NKM-1 NIKzOY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzucpFPUUN3ME2xMlI4PTB4IN88US=> MlraV2FPT0WU
BPH-1 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUX2U2xPUUN3ME2xMlI5PzZ4IN88US=> MojBV2FPT0WU
MES-SA MnezS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYf2eYFwUUN3ME2xMlMxPjh{IN88US=> NHnp[nFUSU6JRWK=
CAL-62 NUTXe4JxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHyTWM2OD1zLkOxPVA6KM7:TR?= Mon1V2FPT0WU
Detroit562 M1nydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjpeXJKSzVyPUGuN|UzOjJizszN M2TIXnNCVkeHUh?=
KYSE-150 NVLqeZE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlTuTWM2OD1zLkO1NlM3KM7:TR?= MUDTRW5ITVJ?
SK-UT-1 Mk\XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkPmTWM2OD1zLkS0OlQ4KM7:TR?= NIXKO4VUSU6JRWK=
HUTU-80 NYXHOoNxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTFwNES4PFYh|ryP NELqS4VUSU6JRWK=
SIG-M5 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEPjV|JKSzVyPUGuOFg{QDdizszN MnfMV2FPT0WU
AGS NVm0O2VET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTFwNUKxNlQh|ryP NWO5[ldWW0GQR1XS
ST486 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVTLRlBjUUN3ME2xMlU{Ojd6IN88US=> NULyfYk6W0GQR1XS
HSC-2 MnfwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIDQV4RKSzVyPUGuOVM6PSEQvF2= MVjTRW5ITVJ?
LCLC-103H NVnJfZpHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHzXIlKSzVyPUGuOVU5OThizszN MmjOV2FPT0WU
BC-1 NV21WXB3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLVTWM2OD1zLk[xOlY1KM7:TR?= NHnhelhUSU6JRWK=
CGTH-W-1 MlXTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTFwNkG2O|kh|ryP M{nr[HNCVkeHUh?=
MZ1-PC NF32XZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{XzRmlEPTB;MT62NlMyOiEQvF2= NV3YdmNlW0GQR1XS
SW1710 NHe4T41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHvZSXVKSzVyPUGuOlI3OjhizszN NY\Xc4M3W0GQR1XS
EW-13 MofJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3i3d2lEPTB;MT62N|Q3PiEQvF2= NFnue|NUSU6JRWK=
TE-11 NYrIR|lUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2L1RmlEPTB;MT62N|UzOiEQvF2= MXXTRW5ITVJ?
BHY MorpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\lTmlEPTB;MT62OVY3OyEQvF2= M4fYWHNCVkeHUh?=
ML-2 M376cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmL0TWM2OD1zLk[2PFAzKM7:TR?= NGrMNplUSU6JRWK=
MEL-JUSO MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPr[JdvUUN3ME2xMlczQDlzIN88US=> MlTrV2FPT0WU
U251 M1fSd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXfkdWN[UUN3ME2xMlc1ODNzIN88US=> M{f6enNCVkeHUh?=
MHH-ES-1 NH3GXFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX6yUm5MUUN3ME2xMlc6PTZ6IN88US=> NXGyVIZYW0GQR1XS
CAL-85-1 NIL3SHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTFwOEC0PUDPxE1? NEfF[HVUSU6JRWK=
D-336MG M3Xv[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlLrTWM2OD1zLki1OlE1KM7:TR?= MnP5V2FPT0WU
VA-ES-BJ M3n0N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILpZmdKSzVyPUGuPVA{OTVizszN NYXvZYtMW0GQR1XS
MDA-MB-468 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnsS3BKSzVyPUGuPVEzPzJizszN Mly3V2FPT0WU
MEL-HO M4HRb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPGZndKSzVyPUGuPVc6QTNizszN NITh[WdUSU6JRWK=
SW954 NFzsTJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mmf4TWM2OD1{LkCwNVUyKM7:TR?= MV3TRW5ITVJ?
LB831-BLC NVvLT2k4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\Q[oRWUUN3ME2yMlAxQTh6IN88US=> MojkV2FPT0WU
EW-16 NIf0NIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTJwMEO5PFMh|ryP M2XlfXNCVkeHUh?=
NCI-H460 NYTMb|BVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTJwMES4N|kh|ryP MXzTRW5ITVJ?
CHP-212 M3\WRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1;LPGlEPTB;Mj6wPVU{QSEQvF2= NI\ybJRUSU6JRWK=
MHH-NB-11 M{\wemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\KcWlEPTB;Mj6xNlgyQCEQvF2= M2DC[XNCVkeHUh?=
DU-4475 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoDHTWM2OD1{LkG0O|U6KM7:TR?= Ml7UV2FPT0WU
ABC-1 M3fafWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFjqdFZKSzVyPUKuNlUyQTZizszN NH\yelhUSU6JRWK=
LOUCY NVq1XVBmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfwTWM2OD1{LkK2NVI5KM7:TR?= MX\TRW5ITVJ?
LC-2-ad NVvlZYV1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTJwMk[5OlYh|ryP MkTxV2FPT0WU
ETK-1 M{nYTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{SxfGlEPTB;Mj6yPFQ3KM7:TR?= NUXlfmZCW0GQR1XS
KYSE-180 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPjSHdKSzVyPUKuNlg5PzRizszN NUfUWpo1W0GQR1XS
HOP-92 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnLZTWM2OD1{LkOwOlc{KM7:TR?= M4XwZ3NCVkeHUh?=
RCC10RGB MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXNTWM2OD1{LkOyOVA4KM7:TR?= M3fPb3NCVkeHUh?=
KASUMI-1 M2LWV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\mTWM2OD1{LkOyPFgh|ryP NFm0VpVUSU6JRWK=
ACN M1Hw[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGK1eIVKSzVyPUKuN|Q4PDVizszN NHP4NYNUSU6JRWK=
BxPC-3 NFPzTnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7CPFk3UUN3ME2yMlM2PDN4IN88US=> NVezWYJSW0GQR1XS
MONO-MAC-6 NV\4[|hpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYPJR|UxRTJwNEGyOFgh|ryP M1XtNXNCVkeHUh?=
CAL-39 NFj4XG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUj4PZE4UUN3ME2yMlQyPjJ6IN88US=> MmLpV2FPT0WU
CMK NV2yWFdjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIrjXIxKSzVyPUKuOFE4QTVizszN NWPVV|ZJW0GQR1XS
MFE-296 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjiTWM2OD1{LkS3O|kzKM7:TR?= NFvZU4hUSU6JRWK=
DU-145 NWHxfmQ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\hWXZuUUN3ME2yMlQ6OTF6IN88US=> NVTGRXdtW0GQR1XS
MDA-MB-231 M1m4Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTJwNEm1O|Ih|ryP MVXTRW5ITVJ?
EFO-27 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTJwNUG4PFgh|ryP MonMV2FPT0WU
SNU-387 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXriXlZYUUN3ME2yMlUzQDJizszN M4PFUnNCVkeHUh?=
KYSE-410 NEPFWFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfJeZZKSzVyPUKuOVY2OTdizszN NWXFXJZ{W0GQR1XS
NCCIT M3rJemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVr3fWMxUUN3ME2yMlU4OjRizszN MYXTRW5ITVJ?
LXF-289 NY\FRmNQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rXWGlEPTB;Mj61PFI4OyEQvF2= MoD1V2FPT0WU
HMV-II MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrXTWM2OD1{LkW4PVk4KM7:TR?= NV;lXFl2W0GQR1XS
MOLT-4 NFjlbY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFmwSIFKSzVyPUKuOlA4OTJizszN MYjTRW5ITVJ?
KOSC-2 NH;zU49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;iTWM2OD1{Lk[zPFc6KM7:TR?= MnzrV2FPT0WU
TUR MkDaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTJwNkWzOlkh|ryP NWXLTZlyW0GQR1XS
NCI-H2087 NYLvPGs6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTs[nc4UUN3ME2yMlcyPjR4IN88US=> MnjhV2FPT0WU
SCC-15 NF;SN2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPlUGEyUUN3ME2yMlc2OjV{IN88US=> MUTTRW5ITVJ?
HSC-4 NY\XZm9zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2TVbmlEPTB;Mj63PFM5QSEQvF2= MXjTRW5ITVJ?
G-402 NIrv[4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYntSoFsUUN3ME2yMlgyPDR5IN88US=> NIHTWIhUSU6JRWK=
GP5d NV3QS2FKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlK3TWM2OD1{LkizPFI4KM7:TR?= NECzR2xUSU6JRWK=
IGR-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPiTWM2OD1{LkizPVg4KM7:TR?= M2DzOnNCVkeHUh?=
SK-PN-DW MkfzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXyOXFKSzVyPUKuPFYzODRizszN NXHSOGkzW0GQR1XS
OPM-2 M1rXVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPXTWM2OD1{Lki5PVc5KM7:TR?= M2\B[HNCVkeHUh?=
5637 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfTcXl{UUN3ME2yMlkzPDN7IN88US=> M1H1THNCVkeHUh?=
NCI-H2030 NE[4PVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\SemFKSzVyPUKuPVgxOjlizszN M1jRPHNCVkeHUh?=
SK-LU-1 MkL2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYntdWhyUUN3ME2yMlk5OzN2IN88US=> NVzVTlR2W0GQR1XS
EW-18 M2PrWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrFTZhWUUN3ME2zMlA2OzJizszN M1u4SXNCVkeHUh?=
786-0 NH;hOohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHG3S4tKSzVyPUOuNFU4QDRizszN MoXkV2FPT0WU
NCI-H1963 M3Wwbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHX0W5BKSzVyPUOuNFg5OjVizszN M1zzXnNCVkeHUh?=
A2780 NInEdoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXLlOmNUUUN3ME2zMlExOzRzIN88US=> NUC0XG97W0GQR1XS
NCI-H526 NHjUNnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPQW3RIUUN3ME2zMlE{QTZzIN88US=> NUeyNVhlW0GQR1XS
BHT-101 NH\NRWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXvNdVU3UUN3ME2zMlE2Pzl6IN88US=> NF\ZNpVUSU6JRWK=
RPMI-7951 NXLIdYZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{OxUWlEPTB;Mz6yNFE{PyEQvF2= NVvLW4hzW0GQR1XS
HL-60 NYjvfo5PT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjYTWM2OD1|LkKxNVQh|ryP NI\oc2RUSU6JRWK=
CTV-1 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTNwMkWzO|ch|ryP NVfDcJFpW0GQR1XS
IST-SL1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRTNwMkm0OlUh|ryP MmXPV2FPT0WU
G-401 M1fN[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorwTWM2OD1|LkK5PFA5KM7:TR?= NHfqWYVUSU6JRWK=
OVCAR-5 NXnRVnZOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LxeWlEPTB;Mz6zOlM2OiEQvF2= NHXLeZJUSU6JRWK=
EW-1 NH3H[mFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWSyOXlJUUN3ME2zMlQxPTR2IN88US=> NV\VNphqW0GQR1XS
H4 MojJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDQU5lqUUN3ME2zMlQ4PTZ7IN88US=> M2jLfHNCVkeHUh?=
EM-2 NXfpTYxrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXjERXdoUUN3ME2zMlQ5Pjd2IN88US=> NYfDenRqW0GQR1XS
RS4-11 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3eyUWlEPTB;Mz60PFcyPSEQvF2= NWjyS5k6W0GQR1XS
NOMO-1 M1fBVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTIbINKSzVyPUOuOFkzODRizszN MVnTRW5ITVJ?
HCT-116 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfrOGtKSzVyPUOuOVA4OTFizszN NI\LUY5USU6JRWK=
CAL-120 M1rI[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTNwNUezOUDPxE1? MkPqV2FPT0WU
CAL-51 NEKxWnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml\GTWM2OD1|LkW3OlEzKM7:TR?= NX7WbI9NW0GQR1XS
RVH-421 Mly5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTNwNkCzNVEh|ryP M1facnNCVkeHUh?=
NCI-H2081 MnflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPaTWM2OD1|Lk[1Nlg5KM7:TR?= NGPrfllUSU6JRWK=
SBC-5 NFvDdItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXP1eJc3UUN3ME2zMlY4QDh{IN88US=> MmrUV2FPT0WU
RL95-2 MlTxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MY\JR|UxRTNwN{G4OlQh|ryP M4G3N3NCVkeHUh?=
SW872 NVnRT2lwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUK2WIg5UUN3ME2zMlc3QTV6IN88US=> NWjzfZV3W0GQR1XS
VM-CUB-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXHT3BKSzVyPUOuO|c2OSEQvF2= MYrTRW5ITVJ?
SUP-T1 NGLnblNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnvtTWM2OD1|Lke4N|Ih|ryP NXm3fodEW0GQR1XS
697 MoH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVj4e4E1UUN3ME2zMlgyPjV5IN88US=> MWjTRW5ITVJ?
DBTRG-05MG Mlz1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYjMNVZKUUN3ME2zMlgyPjd4IN88US=> MnnBV2FPT0WU
TE-441-T NH76RYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3fSXGlEPTB;Mz64Nlk{KM7:TR?= MYDTRW5ITVJ?
A204 NET1OIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlG4TWM2OD1|LkmwPVU3KM7:TR?= M4PzbXNCVkeHUh?=
HCC2998 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYThWVBzUUN3ME2zMlk1QDR|IN88US=> MmnqV2FPT0WU
SCC-4 NUXhPYM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLpWWI{UUN3ME2zMlk2Pzh{IN88US=> MmTSV2FPT0WU
ACHN NEHsTItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4S5N2lEPTB;ND6wNlM4KM7:TR?= NUXF[olZW0GQR1XS
NB1 NH;nRW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvoTWM2OD12LkC2OlQ1KM7:TR?= NFnVPFZUSU6JRWK=
PANC-08-13 M1SydGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\4TWM2OD12LkC3O|Mh|ryP NGW2fFlUSU6JRWK=
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NCI-H747 NYHJNFZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFTZNo9KSzVyPUSuNFg3PzRizszN NIPoS4NUSU6JRWK=
G-361 NXrNZ3l3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlKyTWM2OD12LkC5NFYh|ryP MULTRW5ITVJ?
NCI-H292 M1v1NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPxTWM2OD12LkC5OFI6KM7:TR?= MnztV2FPT0WU
HGC-27 MkDvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1nreWlEPTB;ND6wPVU1QSEQvF2= NUTDVFltW0GQR1XS
ATN-1 NEjvflZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTRwMUC3O|ch|ryP NUXDUWNUW0GQR1XS
RPMI-2650 Ml7jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTRwMUK5O|Uh|ryP NYC4NFZHW0GQR1XS
SIMA NELENW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\OTWM2OD12LkG0OEDPxE1? M4LoSXNCVkeHUh?=
CA46 NHPTSmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTRwMU[xNFQh|ryP M2ez[nNCVkeHUh?=
CHL-1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{\QOmlEPTB;ND6xPFk3OSEQvF2= MlPNV2FPT0WU
TE-10 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGm4d4VKSzVyPUSuNlI5QDdizszN NHnWSplUSU6JRWK=
NCI-H1734 M17kRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn;JTWM2OD12LkK2Olk2KM7:TR?= MU\TRW5ITVJ?
DV-90 M1T4bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUeyc29zUUN3ME20MlI6Ozl5IN88US=> M2XKWXNCVkeHUh?=
MOLT-16 M2[5Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M376fmlEPTB;ND6zNVAyPiEQvF2= NXjTTXg2W0GQR1XS
HuCCT1 NYjPS4tVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2TtRmlEPTB;ND6zN|czOyEQvF2= MoXuV2FPT0WU
A3-KAW NXP4O|ZlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTRwM{W1OVIh|ryP NWrTZ4FNW0GQR1XS
HOS MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFT1V|BKSzVyPUSuN|g2PjdizszN MmSxV2FPT0WU
KS-1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFO1NINKSzVyPUSuOFI1PTlizszN MYHTRW5ITVJ?
SNU-423 NVvnTIRQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfRTWM2OD12LkSyOlg2KM7:TR?= MX3TRW5ITVJ?
BC-3 NVHZbo53T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkPkTWM2OD12LkSzOFc4KM7:TR?= MnrPV2FPT0WU
SCC-9 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7Q[m9jUUN3ME20MlQ1Ojl7IN88US=> NV34b45TW0GQR1XS
C8166 NX62UGptT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzQNWhKSzVyPUSuOFc4PTNizszN M3rsS3NCVkeHUh?=
NCI-H358 M4DQUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TKVWlEPTB;ND60PFU{OiEQvF2= NHzveY9USU6JRWK=
GT3TKB NEnsS3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnH4TWM2OD12LkS4PFIzKM7:TR?= NWXQZpVYW0GQR1XS
NCI-SNU-1 MmjFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;qdXJKSzVyPUSuOFk4ODFizszN NXX2d|hxW0GQR1XS
Ca9-22 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7PTWM2OD12LkW1OVE3KM7:TR?= NXnhfnJbW0GQR1XS
L-363 M{T6Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTRwNUW5PVYh|ryP MUXTRW5ITVJ?
Calu-1 NGXoNoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHTTWM2OD12LkW4O|A4KM7:TR?= M{XObHNCVkeHUh?=
OE19 NH7MNIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zWemlEPTB;ND62N|E1PSEQvF2= NWjGWYFPW0GQR1XS
COR-L23 MniyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWT4[3gzUUN3ME20MlY4OjhizszN MYTTRW5ITVJ?
A431 MoDES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LRSGlEPTB;ND62PFIzQCEQvF2= M3;pXHNCVkeHUh?=
MKN1 NFHKVXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGC5fZpKSzVyPUSuO|A3PjVizszN MXLTRW5ITVJ?
SH-4 NIHlXXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIDqWopKSzVyPUSuO|I3OzNizszN MoHHV2FPT0WU
SNB75 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXnJR|UxRTRwN{S2OkDPxE1? Mny4V2FPT0WU
SW780 MlPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXzjbo1VUUN3ME20Mlc3QDR7IN88US=> M{TnUXNCVkeHUh?=
GOTO M4K0PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTRwN{myPVMh|ryP MX7TRW5ITVJ?
U-266 MoXCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTRwOUS5NVkh|ryP NITkd49USU6JRWK=
KURAMOCHI M4TmZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWLUVJRTUUN3ME21MlAzQDN2IN88US=> NX\6bnY2W0GQR1XS
NMC-G1 NEHqfoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnvbm5IUUN3ME21MlA6OTN7IN88US=> MoPRV2FPT0WU
COLO-684 M3TPXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXK3bm5nUUN3ME21MlI2OzdzIN88US=> NHjjdWtUSU6JRWK=
NTERA-S-cl-D1 NFPON3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjGTWM2OD13LkK5NlE5KM7:TR?= M2DMS3NCVkeHUh?=
RD MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3v4fWlEPTB;NT6yPVc4OSEQvF2= M3jJXnNCVkeHUh?=
A2058 M2rEXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTVwM{C0N|gh|ryP NHnFenRUSU6JRWK=
NCI-H2009 MorIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmD4TWM2OD13LkOwOVM5KM7:TR?= MmjEV2FPT0WU
8-MG-BA MoXMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M13UdWlEPTB;NT6zO|A4PyEQvF2= NEjo[IRUSU6JRWK=
LC4-1 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVrjXoZ{UUN3ME21MlM6OzB|IN88US=> NV;IOHpuW0GQR1XS
A101D M2P0[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVjJR|UxRTVwM{m2PFkh|ryP MnTZV2FPT0WU
ES8 NWP1bIlpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fUdmlEPTB;NT60NVQxQSEQvF2= M4W2fXNCVkeHUh?=
SF126 NILESYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\RTWM2OD13LkSxOFY2KM7:TR?= NIGyeGpUSU6JRWK=
GDM-1 NH7jVlBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHpRZdEUUN3ME21MlQyPzhzIN88US=> MY\TRW5ITVJ?
TE-6 MnHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTVwNES1Olkh|ryP NF;jRnNUSU6JRWK=
SR M{\UeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPLUFdpUUN3ME21MlU{PjR3IN88US=> MYHTRW5ITVJ?
HOP-62 MmnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTVwNU[4PFch|ryP M3zHS3NCVkeHUh?=
HCC2157 MoPWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3rUSWlEPTB;NT61Olg6PiEQvF2= M2XO[3NCVkeHUh?=
TE-15 MmXVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTVwNUe3O|kh|ryP M{DOenNCVkeHUh?=
BFTC-905 Mn7KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnXfYlKSzVyPUWuOlA1OjFizszN M2DYe3NCVkeHUh?=
TE-9 NFewOHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfaTWM2OD13Lk[xO|g5KM7:TR?= M1mzNnNCVkeHUh?=
647-V MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mkj1TWM2OD13Lk[yNFQzKM7:TR?= M4TOcnNCVkeHUh?=
KG-1 M{TmRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDac|dKSzVyPUWuO|QxODVizszN NVLpbGlqW0GQR1XS
KYSE-510 Mlq4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWmxfY9jUUN3ME21Mlc6PThzIN88US=> Ml\NV2FPT0WU
SK-MES-1 Mn25S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoSxTWM2OD13Lki1PFkyKM7:TR?= NG\xNmNUSU6JRWK=
OVCAR-3 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILwO3dKSzVyPUWuPFgzODZizszN NH3ldXpUSU6JRWK=
LB1047-RCC NGLSWlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRTVwOUCxOFgh|ryP M2q5VnNCVkeHUh?=
HEL Mn:wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTZwMEKxPFgh|ryP M4XXS3NCVkeHUh?=
KARPAS-45 NX;HcXZCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTZwMEO3PFch|ryP M1zVXXNCVkeHUh?=
NCI-H1304 M1PHZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTZwMUK0PVch|ryP NVjke2lZW0GQR1XS
PC-3 MnXyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxRTZwMUOwO|Ih|ryP Ml;MV2FPT0WU
Calu-3 NIXRT2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjKZlJrUUN3ME22MlE1Pjh7IN88US=> MXjTRW5ITVJ?
NCI-H1648 MnSwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfoZZhKSzVyPU[uNVUyPiEQvF2= MXPTRW5ITVJ?
HSC-3 NUTKTm1zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnWxTWM2OD14LkG3N|k3KM7:TR?= NULMXYJ6W0GQR1XS
COLO-824 M{ixXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnzoTWM2OD14LkK3PFY5KM7:TR?= MW\TRW5ITVJ?
COLO-680N MoGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\mTWM2OD14LkO3OlM5KM7:TR?= MUXTRW5ITVJ?
SK-NEP-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\rSmlEPTB;Nj60NFM3KM7:TR?= Mo\IV2FPT0WU
SCC-25 NHrhOYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHtXHhzUUN3ME22MlQzPDl|IN88US=> MnvIV2FPT0WU
SF295 NVLiPVEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmn2TWM2OD14LkS0PVgh|ryP M33EU3NCVkeHUh?=
no-10 Mkm0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnTJTWM2OD14LkS3PFQh|ryP NFSwe5pUSU6JRWK=
NCI-H838 M1jnfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjBTWM2OD14LkWxO|A{KM7:TR?= NEHHW4lUSU6JRWK=
M059J Mn;MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3XGOWlEPTB;Nj61OVYzPSEQvF2= NUH2XVlXW0GQR1XS
Calu-6 MkTqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLaTWM2OD14Lk[1OFM2KM7:TR?= MWDTRW5ITVJ?
TE-12 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{K0WGlEPTB;Nj63NlM4PyEQvF2= NEfy[ohUSU6JRWK=
639-V MlzjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYLJR|UxRTZwN{WxNlch|ryP MV7TRW5ITVJ?
ESS-1 MmHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2S1NmlEPTB;Nj63OlA4OiEQvF2= MkW5V2FPT0WU
C-4-II NF;3b|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2T3dWlEPTB;Nj64N|EyPyEQvF2= NIr4OIxUSU6JRWK=
23132-87 NWXvPIIzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn;mTWM2OD14LkmwPVAyKM7:TR?= MYrTRW5ITVJ?
MEG-01 NW\OS5NoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHPTWM2OD14LkmzOVQ3KM7:TR?= MUHTRW5ITVJ?
GI-1 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVzIcnZ5UUN3ME22Mlk1OzR6IN88US=> MX7TRW5ITVJ?
NCI-H2347 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULrcYd7UUN3ME22Mlk1PzF3IN88US=> MnXmV2FPT0WU
MS-1 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTZwOUWxPVIh|ryP MlXJV2FPT0WU
SK-MEL-30 NHTnSodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXzTWM2OD14Lkm2N|E2KM7:TR?= M2m5cXNCVkeHUh?=
YKG-1 NIXsSYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\BdHBKSzVyPUeuNFI3PzhizszN NV3sRWh3W0GQR1XS
HT-3 NGrOfnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTtSnQ5UUN3ME23MlA{PDlizszN NYXxbVVpW0GQR1XS
NCI-H2126 Ml\MS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTdwMEm3PVEh|ryP NWnuPJVvW0GQR1XS
GI-ME-N NITNe4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTdwMU[5NFYh|ryP NH\LPFZUSU6JRWK=
LB771-HNC M3mzbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPIXHA3UUN3ME23MlE5ODN6IN88US=> MnrDV2FPT0WU
LCLC-97TM1 NX61RmM{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnUe3BlUUN3ME23MlIyOjd|IN88US=> NWrOPFlkW0GQR1XS
HO-1-N-1 Mkm2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTdwMkSwNlQh|ryP NIDrbXBUSU6JRWK=
HCC1143 NVTrZnpFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUj3eJJuUUN3ME23MlM4QDl6IN88US=> MnLoV2FPT0WU
HuO9 NGjKW3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLlXYdJUUN3ME23MlQ5Pzl2IN88US=> MknkV2FPT0WU
IST-SL2 NIfkT4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX3uXIJTUUN3ME23MlUzOjd{IN88US=> M3uxRXNCVkeHUh?=
MLMA MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3X0S2lEPTB;Nz61OFY5QSEQvF2= NWrrNFlKW0GQR1XS
22RV1 NEnMOGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUTTXph1UUN3ME23MlY4QTd3IN88US=> NWq5WFc1W0GQR1XS
ONS-76 M4\NfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDRTWM2OD15Lk[5OFE3KM7:TR?= MWPTRW5ITVJ?
ECC12 NI\B[mVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1rxN2lEPTB;Nz63NlkxOSEQvF2= NGLmdIlUSU6JRWK=
HT-1080 NFKyU4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\HXFJMUUN3ME23Mlc5PTV3IN88US=> MmjhV2FPT0WU
SF268 NWnHbGlrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3W4dmlEPTB;Nz64N|U3KM7:TR?= MXjTRW5ITVJ?
COLO-800 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{DWNmlEPTB;Nz65NFY5PSEQvF2= MYHTRW5ITVJ?
BB30-HNC M1nvN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTdwOUS1OVMh|ryP MX;TRW5ITVJ?
CAKI-1 NWrFOFNQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1:yPGlEPTB;OD6wOlUzOSEQvF2= Mle5V2FPT0WU
GCIY MnK3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1fhc2lEPTB;OD6yN|cyOyEQvF2= NXLLb2t2W0GQR1XS
MKN28 MoPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlHLTWM2OD16LkK0OVk5KM7:TR?= NUfHXo56W0GQR1XS
IPC-298 NHS2THdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vyVWlEPTB;OD6yO|cxQSEQvF2= MYHTRW5ITVJ?
NCI-H1650 NImyPHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjtb28xUUN3ME24MlI6OTh3IN88US=> MnThV2FPT0WU
KP-N-YS MmjwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2i4dmlEPTB;OD6yPVMxQCEQvF2= MX3TRW5ITVJ?
J82 NFTpPJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRThwM{SxNlQh|ryP Mk\IV2FPT0WU
SK-HEP-1 NIDMV3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV7XPFA{UUN3ME24MlM2PzJ|IN88US=> MVPTRW5ITVJ?
PANC-03-27 MoTvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7VfGVqUUN3ME24MlM3QTJizszN NUTLPHJXW0GQR1XS
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RPMI-8402 MmjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTF|LkWwN|Eh|ryP MXPTRW5ITVJ?
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NUGC-3 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zBT2lEPTB;MUOuO|Q2OyEQvF2= MVPTRW5ITVJ?
CAL-72 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHXVXlSUUN3ME2xOE4yQTB4IN88US=> NV;1ZopFW0GQR1XS
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EW-7 NVzlbY9mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjZ[VZJUUN3ME2yNE4yPjJ6IN88US=> M3vyOXNCVkeHUh?=
Raji M{DGd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPITWM2OD1{MD6yOVY5KM7:TR?= NUm5NpNkW0GQR1XS
LB2518-MEL NV71TGdtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjIc41KSzVyPUKwMlM6PTNizszN M3jDXnNCVkeHUh?=
PANC-10-05 M1j1VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHXcJlKSzVyPUKwMlQ3OTNizszN MnjhV2FPT0WU
MZ2-MEL NFm2PW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1uwbmlEPTB;MkCuOVgyPCEQvF2= NHq4OHNUSU6JRWK=
MFE-280 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTDTWM2OD1{MT6zNVg5KM7:TR?= NVHMOlgzW0GQR1XS
RKO MmLnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjQ[WtKSzVyPUKxMlMzODJizszN M1PtdXNCVkeHUh?=
KMOE-2 Mn7sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\RWFk6UUN3ME2yNU4{Ojh6IN88US=> MXnTRW5ITVJ?
K5 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTFTIp4UUN3ME2yNU4{QDl|IN88US=> NYLJcoRnW0GQR1XS
NCI-H64 M3XqTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTJzLkS3OVYh|ryP NXLWflNxW0GQR1XS
K-562 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTJzLkS5O|Eh|ryP NYHwUpk1W0GQR1XS
HCE-T M4rTWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTJzLkWwPVQh|ryP M4ntRnNCVkeHUh?=
COLO-792 NW\TdJRJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXL[FVwUUN3ME2yNU42QDJ5IN88US=> MmT4V2FPT0WU
PFSK-1 M37FUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnjxTWM2OD1{MT62PFM4KM7:TR?= NH3CTWFUSU6JRWK=
DOK MmLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;0SWlEPTB;MkGuO|Y5PyEQvF2= M{LBTXNCVkeHUh?=
NCI-H1882 NFvhR4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mor5TWM2OD1{MT64OVk3KM7:TR?= NHvFTY9USU6JRWK=
KNS-81-FD NVrHWoRCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml7pTWM2OD1{MT64OlMyKM7:TR?= NHj5bpdUSU6JRWK=
OCUB-M NEHyZWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXzcYpKSzVyPUKxMlk3QDhizszN NGT6[HdUSU6JRWK=
NCI-H1694 NXv6fnhkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYmwSW5zUUN3ME2yNU46QDZ|IN88US=> NVTHcXRTW0GQR1XS
LS-513 NIXCe49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7DPVFKSzVyPUKyMlA{PjdizszN NF3NU5ZUSU6JRWK=
NCI-H2122 Mk\IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTJ{LkG2O|ch|ryP MVPTRW5ITVJ?
IMR-5 M3PjN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTJ{LkK4O{DPxE1? NGrpdZFUSU6JRWK=
SNU-C2B NX\PZ3FFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPRNldKSzVyPUKyMlY4PDZizszN MnnsV2FPT0WU
A498 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHveHMyUUN3ME2yNk45OTd5IN88US=> M37aeHNCVkeHUh?=
NCI-H727 NHmzS5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEW5SHJKSzVyPUKyMlg5OzZizszN M{LRZXNCVkeHUh?=
SW1573 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPPN|dlUUN3ME2yN{4xPjR4IN88US=> NF:zSo5USU6JRWK=
RO82-W-1 M3PKemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIDVU|BKSzVyPUKzMlI2OTFizszN MlXlV2FPT0WU
SKG-IIIa NVi4bYxbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLy[mRiUUN3ME2yN{4{PTR4IN88US=> MmO4V2FPT0WU
MC-CAR MmHBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M37mWGlEPTB;MkOuOVE5OyEQvF2= NYrqdVJvW0GQR1XS
NCI-H446 NVPVbVlqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIG2V4dKSzVyPUKzMlYxQTNizszN M1TvfXNCVkeHUh?=
PC-14 MmHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHvZZVKSzVyPUKzMlY3OjNizszN NWP4XmhiW0GQR1XS
TGBC1TKB Mn\vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTJ|Lke0OlEh|ryP MnLyV2FPT0WU
EFM-19 MkPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1uxUmlEPTB;MkSuNVg1PCEQvF2= NVq0XJU2W0GQR1XS
SK-N-DZ MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NITx[41KSzVyPUK0MlQ6PzdizszN MkLTV2FPT0WU
NCI-H661 NEW0clFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13odGlEPTB;MkSuOVIyPyEQvF2= NFfodlFUSU6JRWK=
SW1990 MlPDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI[1[VZKSzVyPUK0MlU5QDNizszN MV3TRW5ITVJ?
SW684 NYPRbZBET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTJ2Lke2NlQh|ryP M2DHbnNCVkeHUh?=
Ca-Ski MmXjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTJ2LkmyN|ch|ryP MYfTRW5ITVJ?
TGW MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIqx[3pKSzVyPUK1MlI{OzdizszN MlO5V2FPT0WU
CaR-1 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnHTWM2OD1{NT6zOVch|ryP NGXhR2NUSU6JRWK=
D-247MG M{fmOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF65[WVKSzVyPUK1MlQ4PDNizszN M3TzN3NCVkeHUh?=
CCRF-CEM NUPyXYlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTJ3Lke0OVkh|ryP MX7TRW5ITVJ?
CAPAN-1 MkP1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\uZ2lEPTB;MkWuO|UxOSEQvF2= MVLTRW5ITVJ?
CP50-MEL-B MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTJ3Lkm5NFEh|ryP NIHZWY9USU6JRWK=
FADU Mn;mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmT2TWM2OD1{Nj61NVUzKM7:TR?= NWjE[pFnW0GQR1XS
Daudi MmTES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVrTNWdlUUN3ME2yOk42OTV6IN88US=> NVjNcINQW0GQR1XS
U-87-MG NUDvbnpZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkT2TWM2OD1{Nj61N|A2KM7:TR?= NXfmTpYyW0GQR1XS
DSH1 M{TncWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTJ4LkW0NFYh|ryP MVXTRW5ITVJ?
KYSE-520 NHn1O4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIHZXpBKSzVyPUK2MlU2PTNizszN NVrKVpNGW0GQR1XS
HuH-7 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfC[|hsUUN3ME2yOk46ODh4IN88US=> NFrQNo9USU6JRWK=
U-2-OS Mm\NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLqdoZKSzVyPUK3MlAzPzFizszN NFnhV5FUSU6JRWK=
LU-99A NILBeWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX7i[Xp1UUN3ME2yO{4yPzV2IN88US=> MkXuV2FPT0WU
T98G MmfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlfOTWM2OD1{Nz6xPVc{KM7:TR?= M3eyVXNCVkeHUh?=
MZ7-mel MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGD2VHJKSzVyPUK3MlU2PDhizszN MXTTRW5ITVJ?
SNU-C1 MlHnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYLJR|UxRTJ5Lk[0PVEh|ryP NXW3fnNKW0GQR1XS
MDA-MB-175-VII Ml7SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjGTWM2OD1{Nz62PVc2KM7:TR?= NEGxSVBUSU6JRWK=
HuP-T3 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jrOmlEPTB;MkiuNFQ6PSEQvF2= NXnsbVAxW0GQR1XS
T-24 NGXWXYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfYSWtmUUN3ME2yPE4yQTJ3IN88US=> MVXTRW5ITVJ?
HDLM-2 NVLGd3JyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUf3fJlbUUN3ME2yPE4zPDV7IN88US=> NYKzSYQ5W0GQR1XS
NCI-H1651 M{DBc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTJ6LkK1PVIh|ryP MYnTRW5ITVJ?
SK-N-AS NHPFT4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX\JR|UxRTJ6LkOxO|Eh|ryP NIXiVmpUSU6JRWK=
NY NWf5bFM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWTJR|UxRTJ6Lk[1O|kh|ryP M122cXNCVkeHUh?=
D-283MED M3TRZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTJ6Lki3NFgh|ryP NFTmfVVUSU6JRWK=
KLE MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDV[Zl3UUN3ME2yPE46QTB4IN88US=> MUPTRW5ITVJ?
NCI-H28 MkniS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TGc2lEPTB;MkmuNFEzKM7:TR?= MV;TRW5ITVJ?
TE-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPzN5U5UUN3ME2yPU4zOTZ5IN88US=> MYjTRW5ITVJ?
SK-MEL-24 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{PKXWlEPTB;MkmuOVQ3PiEQvF2= MW\TRW5ITVJ?
CAL-54 NV3leJNMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnMTWM2OD1{OT62NFQ3KM7:TR?= NUn1[2tCW0GQR1XS
A673 MknES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfJdoxKSzVyPUK5Mlc{OiEQvF2= NFy0dHpUSU6JRWK=
HEC-1 M4[1fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojmTWM2OD1|MD6wNFU{KM7:TR?= NYXxW5llW0GQR1XS
LS-411N MmXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HjRWlEPTB;M{CuNVQ4PSEQvF2= MknTV2FPT0WU
SW962 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDMbWRiUUN3ME2zNE4zPDd5IN88US=> NXPGRW02W0GQR1XS
OVCAR-8 NGfLcJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYXZe3Q4UUN3ME2zNE43Pzl2IN88US=> M3fEb3NCVkeHUh?=
NCI-H630 Mn7nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1v2ZWlEPTB;M{CuPFk2OyEQvF2= MkPrV2FPT0WU
D-263MG MnnVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvF[FRKSzVyPUOxMlA1OjRizszN Ml\kV2FPT0WU
NCI-H596 NVTYcFZ[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfYTWM2OD1|MT6wOlIyKM7:TR?= MX;TRW5ITVJ?
BB49-HNC MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTNzLkGxNkDPxE1? MoDpV2FPT0WU
KYSE-70 NHHPbZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTNzLkOwNFgh|ryP MljSV2FPT0WU
LAN-6 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXz1Nnp[UUN3ME2zNU41QTl{IN88US=> NEXJUJlUSU6JRWK=
NCI-H2228 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPZeVZKSzVyPUOxMlU3OjVizszN NETKbJhUSU6JRWK=
SW620 NEi3TWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3X4OmlEPTB;M{GuOlI5OyEQvF2= NIHyRpdUSU6JRWK=
KM-H2 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIPQSIlKSzVyPUOxMlc{ODZizszN NYf0SZVrW0GQR1XS
DJM-1 NHrjem9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTN{LkGzPFYh|ryP MlXhV2FPT0WU
SW48 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17De2lEPTB;M{KuN|gzPSEQvF2= NGTVT4hUSU6JRWK=
NCI-H1793 NEDoNGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2Xl[2lEPTB;M{KuOlE3OyEQvF2= NVzXRo5MW0GQR1XS
LU-165 NXz2cZNnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnkdXpKSzVyPUOzMlAxQCEQvF2= NX3JXJpJW0GQR1XS
EHEB NUTyelFWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3jSYkxUUN3ME2zN{4xPDl2IN88US=> NYDIXnVPW0GQR1XS
NCI-H441 MmXHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX:0cnBiUUN3ME2zN{4zOjN3IN88US=> M1LBbnNCVkeHUh?=
LOXIMVI M3HDPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrNTWM2OD1|Mz6zOlc6KM7:TR?= M1LNW3NCVkeHUh?=
MC-IXC MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILY[WtKSzVyPUOzMlU3PTVizszN NIHy[ZpUSU6JRWK=
NCI-H522 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrmTWM2OD1|Mz62OVQh|ryP MX\TRW5ITVJ?
IA-LM NWfFfVhKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DDRWlEPTB;M{OuOlc1PiEQvF2= MXfTRW5ITVJ?
NCI-H1417 NICxO5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn7DTWM2OD1|Mz65OVg2KM7:TR?= MXLTRW5ITVJ?
HCC2218 NIPJPGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDTTVhIUUN3ME2zOU4zOTh3IN88US=> NGnzbZBUSU6JRWK=
HC-1 NXPmUWNtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3yTWM2OD1|NT60NFI1KM7:TR?= M4nxe3NCVkeHUh?=
HH MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HEPGlEPTB;M{WuOFE1OSEQvF2= MX3TRW5ITVJ?
EFE-184 MoDXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVvJR|UxRTN3Lk[4Nlkh|ryP M3fRN3NCVkeHUh?=
NCI-H1355 M3q5dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTN3Lke3NVgh|ryP NYeyNpgzW0GQR1XS
BV-173 M3nuN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3McXhKSzVyPUO1MlgzPjRizszN MWDTRW5ITVJ?
NEC8 MmrVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1r6XGlEPTB;M{[uOFkzPCEQvF2= NVPOepNVW0GQR1XS
SW1463 NH;4cFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{KybGlEPTB;M{[uOlU3PiEQvF2= NHjsfGZUSU6JRWK=
KYSE-140 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIG2cWFKSzVyPUO2MlczQThizszN MV7TRW5ITVJ?
no-11 NF;sOJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTN4Lki1N|Yh|ryP MkDlV2FPT0WU
HCC1937 M2fzOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTN5LkCxOVQh|ryP M3LmWnNCVkeHUh?=
LNCaP-Clone-FGC MoTWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPtTWM2OD1|Nz6xPVA{KM7:TR?= NEjjOphUSU6JRWK=
KARPAS-422 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFG0T3BKSzVyPUO3MlQ1OzFizszN M3TNbnNCVkeHUh?=
RCM-1 NV7QRnRTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfsNY9ZUUN3ME2zO{42OzV6IN88US=> M3PyU3NCVkeHUh?=
A375 NUX6SZRRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTN5Lke2OFch|ryP MljJV2FPT0WU
TGBC24TKB NIi3PHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUHJR|UxRTN6LkCyN|kh|ryP NIjzOHNUSU6JRWK=
MDA-MB-453 Ml;ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVX6VJZkUUN3ME2zPU4xOjF6IN88US=> M1P6dnNCVkeHUh?=
Capan-2 Mo\LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIm4cmFKSzVyPUO5MlA2ODlizszN MofsV2FPT0WU
SW756 NXzIWnA1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTN7LkWwPVEh|ryP NUPmZmVzW0GQR1XS
KU-19-19 NF3ZdmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPJTWM2OD1|OT62NlgzKM7:TR?= MoXlV2FPT0WU
NCI-H2170 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2H2eWlEPTB;M{muPVk4PyEQvF2= NXrDO4I4W0GQR1XS
COLO-678 M3rzN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnfXTWM2OD12MD61PVUh|ryP MoqyV2FPT0WU
PF-382 Mlr2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml:zTWM2OD12MD63OFg4KM7:TR?= NIj1U5JUSU6JRWK=
OAW-42 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnTdHRpUUN3ME20Nk4zQTR{IN88US=> NWL0NGRVW0GQR1XS
LB996-RCC NU\pe|VxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn\zTWM2OD12Mj64NFA5KM7:TR?= MmnkV2FPT0WU
SAS MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{TPdGlEPTB;NEOuOFI5QCEQvF2= Ml;JV2FPT0WU
MRK-nu-1 NIHqTJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLQ[HJKSzVyPUS0Mlc1OTRizszN NGjrbmdUSU6JRWK=
EoL-1-cell M{H1eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jpOWlEPTB;NESuPVE{PiEQvF2= MmnhV2FPT0WU
NCI-H2342 MkK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\nZWlEPTB;NEWuNVEyPyEQvF2= M2nnNXNCVkeHUh?=
NCI-H1703 NFXCWZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnxdox4UUN3ME20Ok4xPTl{IN88US=> NEP3enJUSU6JRWK=
NCI-H187 NEnCN2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTR4LkG4Olkh|ryP NVjWXW9qW0GQR1XS
CP66-MEL MoDpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTR4LkK3PFkh|ryP NGD5VGZUSU6JRWK=
HCC1569 MlvpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fLVGlEPTB;NE[uOVkyPyEQvF2= NH3OWJpUSU6JRWK=
BL-70 NUTIOlJwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGDTcI5KSzVyPUS2Mlc4OzdizszN M1fZUnNCVkeHUh?=
Saos-2 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\hTnVEUUN3ME20O{4{OTJ|IN88US=> NFHuenBUSU6JRWK=
LC-1F Ml7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTR5Lk[xNFUh|ryP M4fOZnNCVkeHUh?=
KY821 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NITuOpJKSzVyPUS3MlY1OzRizszN M{nXNnNCVkeHUh?=
PSN1 NUnuPHg1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXHnOId7UUN3ME20PE4yPDBzIN88US=> NVXxOGlMW0GQR1XS
RT4 MmTjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnkdo9mUUN3ME20PE45Ozd5IN88US=> NEHzeZZUSU6JRWK=
LS-1034 NH3TNVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkL6TWM2OD12OD64PVU1KM7:TR?= NIiz[2xUSU6JRWK=
NCI-H1395 NFTuV4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{LnOmlEPTB;NEmuNFQ6OiEQvF2= MVLTRW5ITVJ?
EKVX M4r2Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\kOGlEPTB;NEmuOlc{OSEQvF2= NHnUbWdUSU6JRWK=
IST-MES1 NXLsbFJ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnVZ2tKSzVyPUS5Mlg6PDRizszN NHf6[VNUSU6JRWK=

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-FAK / FAK / p-Talin / Talin ; 

PubMed: 26530902     


Dose response of PF-562271 on the phosphorylation of FAK-Y397 or Talin-S425 in PC3-mm2 cells.

p-Src / Src / p-paxillin / Paxillin / ICAM-1 ; 

PubMed: 29417941     


MDA-MB-231 cells transfected with FAK-specific siRNAs or treated for 12 h with PF-562271 at the indicated concentrations were subjected to immunoblotting with indicated antibodies.

26530902 29417941
Immunofluorescence
p-FAK; 

PubMed: 26530902     


Immunostaining of PC3-mm2 cells showed that phosphorylated FAK is localized at focal adhesions (inset).

26530902
Growth inhibition assay
Cell viability; 

PubMed: 28953264     


MTT assay showed inhibition of cell proliferation and viability in HCT116 (B) and SW480 (D) cell lines treated with resveratrol and/or different concentrations of FAK-Inhibitor (PF-562271: 0.01, 0.1, 1, and 10 µM) cultured in monolayer for 12 h. Data shown are representative of three independent sets of experiments. Values were compared with the control and statistically significant values with p < 0.05 are designated by an asterisk (*) and p < 0.01 are designated by two asterisks (**).

28953264
In vivo PF-562271 (< 33 mg/kg p.o.) inhibits FAK phosphorylation in tumors in a dose- and time-dependent manner in U87MG-bearing mice. PF-562271 (50 mg/kg p.o. bid) results in 86% tumor growth inhibition in BxPc3 xenografts mice and 45% tumor growth inhibition in PC3-M xenografts mice. PF-562271 (25 mg/kg, bid) results in 2-fold greater apoptosis in treated tumors in mice bearing H125 lung xenografts. [1] PF-562271 (33 mg/kg, p.o.) inhibits extensive movement of the tumor cells over 24 hours in mice. PF-562271 (33 mg/kg, p.o.) results in altered E-cadherin dynamics in mice, which correlates with reduced E-cadherin–dependent collective cell movement. [3] PF-562271 (25 mg/kg, p.o. bid) results in 62% tumor growth inhibition in PC3M-luc-C6 subcutaneuous local implant xenograft mouse model. [4] PF-562,271 (5 mg/kg, oral) results in significant and similar increases in osteocalcin and cancellous bone parameters and a decrease in tumor growth and signs of bone healing in rats implanted with MDA-MB-231 cells in the tibia. [5]

Protocol

Animal Research:[1]
- Collapse
  • Animal Models: Athymic female mice bearing BxPc3 or PC3-M xenografts.
  • Formulation: 5% Gelucire
  • Dosages: 50 mg/kg
  • Administration: Oral gavage
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL warmed (197.04 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O
For best results, use promptly after mixing.
5 mg/ml

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 507.49
Formula

C21H20F3N7O3S

CAS No. 717907-75-0
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
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    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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FAK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID