Kavain

Catalog No.S9409 Synonyms: (+)-Kavain

For research use only.

Kavain ((+)-Kavain), the main kavalactone found mostly in the roots of the kava plant, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor.

Kavain Chemical Structure

CAS No. 500-64-1

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Biological Activity

Description Kavain ((+)-Kavain), the main kavalactone found mostly in the roots of the kava plant, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 46 mg/mL
(199.77 mM)


Chemical Information

Molecular Weight 230.26
Formula

C14H14O3

CAS No. 500-64-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=CC(=O)OC(C1)C=CC2=CC=CC=C2

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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