Dinitolmide

Catalog No.S4141 Synonyms: Zoalene

For research use only.

Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.

Dinitolmide  Chemical Structure

CAS No. 148-01-6

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Biological Activity

Description Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
In vitro

Dinitolmide is a drug used for the prevention and treatment of coccidiosis in poultry. For prophylactic purposes the drug is used as an additive to poultry feeds at a level of between 40 and 250 p.p.m. and is sometimes used in conjunction with anti-blackhead drugs and antibiotics. Several spectrophotometric methods have been proposed for the determination of dinitolmide. [1]

In vivo Overall mean recoveries greater than 85% are obtained with Zoalene and its 2 monoamino metabolites in breast, thigh, and liver tissues fortified with 0.25-2.00 ppm. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 45 mg/mL
(199.85 mM)
Water Insoluble
Ethanol '1 mg/mL

Chemical Information

Molecular Weight 225.16
Formula

C8H7N3O5

CAS No. 148-01-6
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=C(C=C(C=C1[N+](=O)[O-])[N+](=O)[O-])C(=O)N

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Tech Support

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