Home Microbiology Parasite inhibitor Dinitolmide For research use only.

Dinitolmide

Synonyms: Zoalene

Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.

Dinitolmide Chemical Structure

Dinitolmide Chemical Structure

CAS: 148-01-6

Purity & Quality Control

Batch: S414101 DMSO] 45 mg/mL] false] Ethanol] 1 mg/mL] false] Water] Insoluble] false Purity: 99.7%
99.7

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Biological Activity

Description Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
In vitro
In vitro Dinitolmide is a drug used for the prevention and treatment of coccidiosis in poultry. For prophylactic purposes the drug is used as an additive to poultry feeds at a level of between 40 and 250 p.p.m. and is sometimes used in conjunction with anti-blackhead drugs and antibiotics. Several spectrophotometric methods have been proposed for the determination of dinitolmide. [1]
In Vivo
In vivo Overall mean recoveries greater than 85% are obtained with Zoalene and its 2 monoamino metabolites in breast, thigh, and liver tissues fortified with 0.25-2.00 ppm. [2]

Chemical Information & Solubility

Molecular Weight 225.16 Formula

C8H7N3O5
CAS No. 148-01-6 SDF Download Dinitolmide SDF
Smiles CC1=C(C=C(C=C1[N+](=O)[O-])[N+](=O)[O-])C(=O)N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 45 mg/mL ( (199.85 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 1 mg/mL

Water : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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