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Catalog No. Product Name Information Product Use Citations Product Validations
S0081 DDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
S0467 Emodepside Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
Parasitology, 2020, 1-11
PLoS Negl Trop Dis, 2015, 9(3):e0003593
S1830 Oxfendazole Oxfendazole (RS-8858) is a broad spectrum benzimidazole anthelmintic.
Mol Med Rep, 2019, 19(4):2921-2926
S1837 Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
Sci Rep, 2020, 10(1):13124
RSC Advances, 2018, 10.1039/C7RA12259D
S1851 Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
Oncol Lett, 2018, 15(2):2218-2226
S2028 Diclazuril Diclazuril is an anti-coccidial drug.
Hum Mol Genet, 2020, ddaa244
S2468 Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S2501 Pyrantel Pamoate Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Sci Rep, 2019, 9(1):536
Sci Transl Med, 2015, 7(290):290ra89
S3591New Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
S3707 Ethopabate Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
S3713 Moxidectin Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
S3741 Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
S3889 Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S3999 α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
S4044 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S4068 Tinidazole Tinidazole (CP12574) is an anti-parasitic drug.
S4094 Tetramisole HCl Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
S4104 Diminazene Aceturate Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020
S4141 Dinitolmide Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
S4145 Decoquinate Decoquinate is a coccidiostat.
S4167 Cyromazine Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
S4389 Bephenium Hydroxynaphthoate Bephenium is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
S4422 Nitenpyram Nitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S4564 Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S4599 Benzyl benzoate Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S4610 Mebendazole Mebendazole (Vermox, Telmin, Pantelmin, Mebenvet) is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
Genome Med, 2021, 13(1):146
Aging (Albany NY), 2021, 13(13):17407-17427
Am J Cancer Res, 2020, 10(8):2649-2676
S4866 Nicarbazin Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
S4876 Robenidine Hydrochloride Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.
S4882 Resorantel Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
S4898 Sulfalozine sodium Sulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) is an antiprotozoal useful in coccidiosis research.
S4999 Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
S5017 Oxyclozanide Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.
S5031 Sulfaquinoxaline sodium Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.
S5055 Milbemycin Oxime Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).
S5092 Febantel Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S5093 Rafoxanide Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
S5094 Maduramycin Ammonium Maduramicin, which could be isolated from the actinomycete Actinomadura rubra, is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis.
Cancers (Basel), 2019, 11(6)
S5247 Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.
S5345 Nerolidol Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
Int Immunopharmacol, 2020, 80:106118
S5557 Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S5722 Oxantel Pamoate Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
S5816 Pyrvinium Pyrvinium is an anthelmintic effective for pinworms.
Mol Carcinog, 2021, 10.1002/mc.23308
Med Oncol, 2021, 38(2):21
Front Microbiol, 2020, 11:579362
S5948 Amodiaquine Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
bioRxiv, 2020, 10.1101/2020.04.13.039917
bioRxiv, 2020, 2020/9/20.4.7.30734
S7379 E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
Sci Adv, 2021, 7(3)eabc6364
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Epigenetics Chromatin, 2021, 14(1):23
S0081 DDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.
S0467 Emodepside Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
Parasitology, 2020, 1-11
PLoS Negl Trop Dis, 2015, 9(3):e0003593
S1830 Oxfendazole Oxfendazole (RS-8858) is a broad spectrum benzimidazole anthelmintic.
Mol Med Rep, 2019, 19(4):2921-2926
S1837 Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
Sci Rep, 2020, 10(1):13124
RSC Advances, 2018, 10.1039/C7RA12259D
S1851 Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
Oncol Lett, 2018, 15(2):2218-2226
S2028 Diclazuril Diclazuril is an anti-coccidial drug.
Hum Mol Genet, 2020, ddaa244
S2468 Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S2501 Pyrantel Pamoate Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
S3079 Atovaquone Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Sci Rep, 2019, 9(1):536
Sci Transl Med, 2015, 7(290):290ra89
S3591New Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
S3707 Ethopabate Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
S3713 Moxidectin Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
S3741 Benznidazole Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
S3889 Arteether Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S3999 α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
S4044 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
S4068 Tinidazole Tinidazole (CP12574) is an anti-parasitic drug.
S4094 Tetramisole HCl Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
S4104 Diminazene Aceturate Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020
S4141 Dinitolmide Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.
S4145 Decoquinate Decoquinate is a coccidiostat.
S4167 Cyromazine Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
S4389 Bephenium Hydroxynaphthoate Bephenium is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
S4422 Nitenpyram Nitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
Proc Natl Acad Sci U S A, 2020, 117(21):11321-11327
S4564 Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S4599 Benzyl benzoate Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S4610 Mebendazole Mebendazole (Vermox, Telmin, Pantelmin, Mebenvet) is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
Genome Med, 2021, 13(1):146
Aging (Albany NY), 2021, 13(13):17407-17427
Am J Cancer Res, 2020, 10(8):2649-2676
S4866 Nicarbazin Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
S4876 Robenidine Hydrochloride Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.
S4882 Resorantel Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
S4898 Sulfalozine sodium Sulfalozine sodium (Sulfaclozine sodium, Sulfachlopryrazine sodium) is an antiprotozoal useful in coccidiosis research.
S4999 Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
S5017 Oxyclozanide Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.
S5031 Sulfaquinoxaline sodium Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.
S5055 Milbemycin Oxime Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).
S5092 Febantel Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
S5093 Rafoxanide Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
S5094 Maduramycin Ammonium Maduramicin, which could be isolated from the actinomycete Actinomadura rubra, is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis.
Cancers (Basel), 2019, 11(6)
S5247 Selamectin Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.
S5345 Nerolidol Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
Int Immunopharmacol, 2020, 80:106118
S5557 Aklomide Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S5722 Oxantel Pamoate Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
S5816 Pyrvinium Pyrvinium is an anthelmintic effective for pinworms.
Mol Carcinog, 2021, 10.1002/mc.23308
Med Oncol, 2021, 38(2):21
Front Microbiol, 2020, 11:579362
S5948 Amodiaquine Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
bioRxiv, 2020, 10.1101/2020.04.13.039917
bioRxiv, 2020, 2020/9/20.4.7.30734
S7379 E-64 E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
Sci Adv, 2021, 7(3)eabc6364
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Epigenetics Chromatin, 2021, 14(1):23
S3591New Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.