| S5816 |
Pyrvinium pamoate
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Pyrvinium pamoate(Pyrvinium embonate) is an anthelmintic effective for pinworms.
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Infect Drug Resist, 2025, 18:783-789
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Endocrine, 2024, 10.1007/s12020-024-03887-0
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Adv Healthc Mater, 2023, e2300591.
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| S4610 |
Mebendazole
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Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. This compound interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
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Cancers (Basel), 2022, 14(17)4196
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Molecules, 2022, 27(23)8127
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Adv Biol (Weinh), 2022, 6(8):e2200030
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| S5948 |
Amodiaquine
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Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
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Cell Death Discov, 2024, 10(1):434
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Molecules, 2024, 29(6)1363
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Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9
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| S4104 |
Diminazene Aceturate
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Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
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Sci Rep, 2025, 15(1):18633
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Cell, 2024, 187(15):4095-4112.e21
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Cell, 2024, 187(15):4095-4112.e21
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| S1691 |
Praziquantel
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Praziquantel is an anthelmintic effective against flatworms.
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Parasitology, 2020, 1-11
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PLoS Negl Trop Dis, 2015, 9(3):e0003593
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| S2028 |
Diclazuril
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Diclazuril(R-64433) is an anti-coccidial drug.
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Hum Mol Genet, 2020, ddaa244
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| S1851 |
Oxibendazole
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Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
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J Control Release, 2025, 380:417-432
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Oncol Lett, 2018, 15(2):2218-2226
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| S1830 |
Oxfendazole
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Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.
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Mol Med Rep, 2019, 19(4):2921-2926
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| S3741 |
Benznidazole
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Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
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Int J Mol Sci, 2024, 25(8)4413
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Microorganisms, 2022, 10(7)1421
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| S4068 |
Tinidazole
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Tinidazole (CP12574) is an anti-parasitic drug.
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Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
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Int J Mol Sci, 2024, 25(8)4413
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Microorganisms, 2022, 10(7)1421
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