For research use only.

Catalog No.S1691

2 publications

Praziquantel Chemical Structure

CAS No. 55268-74-1

Praziquantel is an anthelmintic effective against flatworms.

Selleck's Praziquantel has been cited by 2 publications

1 Customer Review

  • Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.

    PLoS Negl Trop Dis, 2015, 9(3):e00035.. Praziquantel purchased from Selleck.

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Biological Activity

Description Praziquantel is an anthelmintic effective against flatworms.



Solubility (25°C)

In vitro DMSO 63 mg/mL (201.65 mM)
Water Insoluble
Ethanol '63 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 312.41


CAS No. 55268-74-1
Storage powder
in solvent
Synonyms N/A
Smiles C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

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The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04635553 Recruiting Drug: Praziquantel 600 milligram Schistosomiasis Institut de Recherche pour le Developpement August 11 2020 --
NCT04314037 Completed Drug: Cesol (Test)|Drug: Biltricide (Reference) Healthy Merck Healthcare KGaA Darmstadt Germany an affiliate of Merck KGaA Darmstadt Germany June 17 2020 Phase 1
NCT03870204 Active not recruiting Diagnostic Test: POC-CCA rapid urine test Aged ≥2 Years in Schistosomiasis Affected Areas Ina-Respond|National Institute of Health Research and Development Ministry of Health Republic of Indonesia|The National Institute of Allergy and Infectious Diseases United States September 4 2019 --
NCT03437447 Completed Drug: Cisticid|Drug: Biltricide Healthy Merck KGaA Darmstadt Germany June 18 2018 Phase 1
NCT02194712 Completed Other: Urine CAA detection Schistosomiasis Meta Roestenberg|Leiden University Medical Center January 2015 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID