Praziquantel

For research use only.

Catalog No.S1691

2 publications

Praziquantel Chemical Structure

CAS No. 55268-74-1

Praziquantel is an anthelmintic effective against flatworms.

Size Price Stock Quantity  
10mM (1mL in DMSO) EUR 127 In stock
EUR 95 In stock
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Selleck's Praziquantel has been cited by 2 publications

1 Customer Review

  • Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.

    PLoS Negl Trop Dis, 2015, 9(3):e00035.. Praziquantel purchased from Selleck.

Purity & Quality Control

Choose Selective Anti-infection Inhibitors

Biological Activity

Description Praziquantel is an anthelmintic effective against flatworms.

Protocol

References

Solubility (25°C)

In vitro DMSO 63 mg/mL (201.65 mM)
Water Insoluble
Ethanol '63 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 312.41
Formula

C19H24N2O2

CAS No. 55268-74-1
Storage powder
in solvent
Synonyms N/A
Smiles C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

  • C1=C0/X C1: LOG(C1):
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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04314037 Completed Drug: Cesol (Test)|Drug: Biltricide (Reference) Healthy Merck Healthcare KGaA Darmstadt Germany an affiliate of Merck KGaA Darmstadt Germany June 17 2020 Phase 1
NCT03870204 Recruiting Diagnostic Test: POC-CCA rapid urine test Aged ≥2 Years in Schistosomiasis Affected Areas Ina-Respond|National Institute of Health Research and Development Ministry of Health Republic of Indonesia|The National Institute of Allergy and Infectious Diseases United States September 4 2019 --
NCT03437447 Completed Drug: Cisticid|Drug: Biltricide Healthy Merck KGaA Darmstadt Germany June 18 2018 Phase 1
NCT02194712 Completed Other: Urine CAA detection Schistosomiasis Meta Roestenberg|Leiden University Medical Center January 2015 --
NCT02271984 Completed Drug: MSC2499550A|Drug: Cysticide Healthy Merck KGaA Darmstadt Germany October 31 2014 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID