FAAH

Signaling Pathway Map

Research Area

Inhibitory Selectivity

FAAH Products

New FAAH Products
Catalog No. Information Product Use Citations Product Validations
S2631

URB597

URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.

S2666

PF-3845

PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.

S5329New

FAAH-IN-2

FAAH-IN-2 is an inhibitor of fatty acid amide hydrolase (FAAH).

S2377

Biochanin A

Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.

S2828

JNJ-1661010

JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.

S5932New

BIA 10-2474

BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor, with a potent inhibitory effect upon FAAH and prolonged action in vivo.

Catalog No. Information Product Use Citations Product Validations
S2631

URB597

URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.

S2666

PF-3845

PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.

S5329New

FAAH-IN-2

FAAH-IN-2 is an inhibitor of fatty acid amide hydrolase (FAAH).

S2377

Biochanin A

Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.

S2828

JNJ-1661010

JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.

S5932New

BIA 10-2474

BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor, with a potent inhibitory effect upon FAAH and prolonged action in vivo.

Tags: FAAH inhibition | FAAH activity | FAAH assay | FAAH inhibitors clinical trials | FAAH inhibitor review