FAAH

All (8) FAAH Inhibitors (8) New FAAH Products

Catalog No.	Information	Product Use Citations
S2631	URB597 URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.
S2666	PF-3845 PF-3845 is a potent, selective and irreversible FAAH inhibitor with K_i of 230 nM, showing negligible activity against FAAH2.
S5329	FAAH-IN-2 FAAH-IN-2 is an inhibitor of fatty acid amide hydrolase (FAAH).
S6609^New	JZL195 JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.
S2377	Biochanin A Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.	Cytotechnology, 2016, 68(4):1633-40
S2421^New	PF-04457845 PF-04457845 is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
S2828	JNJ-1661010 JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
S5932	BIA 10-2474 BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor, with a potent inhibitory effect upon FAAH and prolonged action in vivo.

Catalog No.	Information	Product Use Citations
S2631	URB597 URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.
S2666	PF-3845 PF-3845 is a potent, selective and irreversible FAAH inhibitor with K_i of 230 nM, showing negligible activity against FAAH2.
S5329	FAAH-IN-2 FAAH-IN-2 is an inhibitor of fatty acid amide hydrolase (FAAH).
S6609^New	JZL195 JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.
S2377	Biochanin A Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.	Cytotechnology, 2016, 68(4):1633-40
S2421^New	PF-04457845 PF-04457845 is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
S2828	JNJ-1661010 JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
S5932	BIA 10-2474 BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor, with a potent inhibitory effect upon FAAH and prolonged action in vivo.