| S7365 |
AdipoRon
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AdipoRon (SC-396658) is a novel, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively.
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Aging Cell, 2025, 24(2):e14390
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Sci Adv, 2025, 11(29):eadv6642
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Environ Health Perspect, 2024, 132(11):117003
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| S3822 |
Schisandrin A
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Schisandrin A (Sch A, Deoxyschizandrin, Wuweizisu A) is an active component of Schisandrae Fructus with liver-protective, antitumor, and antioxidant activities. It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM.
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| S4738 |
Arctiin
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Arctiin (Arctigenin-4-Glucoside, NSC 315527) acts on an agonists of the adiponectin receptor 1 with anti-cancer effects.
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| S2304 |
Gramine
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Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. This compound is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist.
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