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Taste Receptor Inhibitors/Activators | Agonists

Isoform-selective Products

Taste Receptor Products

  • All (3)
  • Taste Receptor Inhibitor (1)
  • Taste Receptor Activator (1)
  • Taste Receptor Agonist (1)
  • New Taste Receptor Products
Cat.No. Product Name Information Product Use Citations Product Validations
S4022 Probenecid Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. This compound is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.
BMC Vet Res, 2025, 21(1):237
Mil Med Res, 2024, 11(1):41
Front Immunol, 2022, 13:992505
S9006 Perillartine Perillartine (Perilla sugar, Peryllartine) is a sweetener. This compound can activation of the Tas1r2 monomeric receptors of human, rhesus monkey and squirrel monkey but not mouse in a species-dependent manner.
S1273 Amarogentin

Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. This compound is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. It induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. This chemical interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.
S4022 Probenecid Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. This compound is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.
BMC Vet Res, 2025, 21(1):237
Mil Med Res, 2024, 11(1):41
Front Immunol, 2022, 13:992505
S9006 Perillartine Perillartine (Perilla sugar, Peryllartine) is a sweetener. This compound can activation of the Tas1r2 monomeric receptors of human, rhesus monkey and squirrel monkey but not mouse in a species-dependent manner.
S1273 Amarogentin

Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. This compound is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. It induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. This chemical interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.