• TRPA
  • TRPC
  • TRPM

TRPM Selective Inhibitors | Agonists | Antagonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S0174 TRPM8 antagonist 2 TRPM8 antagonist 2 (TRPM8 Antagonist) is a potent and selective antagonist of TRPM8 with IC50 of 0.2 nM that can be used for the pharmacological treatment of neuropathic pain syndromes. Selective TRPM8, IC50: 0.2 nM
S6638 AMG-333 AMG-333 is a potent and highly selective antagonist of TRPM8 with IC50 values of 13 nM and 30 nM for human TRPM8 and rat TRPM8. Selective rat TRPM8, IC50: 30 nM
S2963 WS-12 WS-12 is a potent TRPM8 agonist with an EC50 of 39 nM. Selective TRPM8, EC50: 39 nM
S6122 Cyclohexanecarboxamide Cyclohexanecarboxamide (Ethyl menthane carboxamide, WS3, Hexahydrobenzamide) is a cooling agent and an agonist at TRPM8 receptors (EC50 = 3.7 μM). Selective TRPM8, EC50: 3.7 μM
S6070 CBA (TRPM4-IN-5) CBA (TRPM4-IN-5, Compound 5) is a highly selective blocker of the TRPM4 ion channel with an IC50 of 1.5μM. Selective TRPM4, IC50: 1.5µM
S3605 Borneol Borneol is a bicyclic monoterpenoid compound extracted from medicinal plants such as Blumea balsamifera, and Dryobalanops aromatica. It is a TRPM8 agonist that increases ocular surface wetness. Selective TRPM8, EC50: 65 μM