PRMT6 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8112 MS023

MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively.

Pan PRMT6, IC50: 4 nM
s8147 MS049

MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively.

Pan PRMT6, IC50: 43 nM
S8858 GSK3368715 (EPZ019997) 3HCl

GSK3368715 is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.

Pan