Home Methylation -Epigenetics PRMT PRMT4 Selective Inhibitors

PRMT4 Selective Inhibitors

  • PRMT5
  • PRMT4
  • PRMT6
  • PRMT1
  • PRMT8
  • PRMT3
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8340 SGC2085 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >100-fold selective over other PRMTs. Selective CARM1, IC50: 50 nM
s8147 MS049 MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. Pan PRMT4, IC50: 34 nM
S8112 MS023 MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. Pan PRMT4, IC50: 83 nM
S8858 GSK3368715 3HCl GSK3368715 3HCl is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. Pan