• PAD1
  • PAD3
  • PAD4

PAD4 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium. Selective PAD4, IC50: 50 nM
S8141 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis. Pan PAD4, IC50: 5.9 μM