PAD

Inhibitory Selectivity

Isoform-specific Inhibitors

PAD Products

Catalog No. Information Product Use Citations Product Validations
S7803

GSK484 HCl

GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Phytomedicine, 2021, 90:153635
Hum Exp Toxicol, 2020, 960327120979028
S8141

Cl-amidine

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Phytomedicine, 2021, 90:153635
Ecotoxicol Environ Saf, 2021, 211:111900
Cancer Cell, 2020, S1535-6108(20)30660-7
Catalog No. Information Product Use Citations Product Validations
S7803

GSK484 HCl

GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Phytomedicine, 2021, 90:153635
Hum Exp Toxicol, 2020, 960327120979028
S8141

Cl-amidine

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Phytomedicine, 2021, 90:153635
Ecotoxicol Environ Saf, 2021, 211:111900
Cancer Cell, 2020, S1535-6108(20)30660-7