PAD

Inhibitory Selectivity

PAD Products

All (2) PAD Inhibitors (2)

Catalog No.	Information	Product Use Citations	Product Validations
S7803^New	GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.	Hum Exp Toxicol, 2020, 960327120979028
S8141	Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.	Ecotoxicol Environ Saf, 2021, 211:111900 Cancer Cell, 2020, S1535-6108(20)30660-7 Int Immunopharmacol, 2020, 13;84:106583

Catalog No.

Information

Product Use Citations

Product Validations

S7803^New

GSK484 HCl

GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.

Hum Exp Toxicol, 2020, 960327120979028

S8141

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.

Ecotoxicol Environ Saf, 2021, 211:111900

Cancer Cell, 2020, S1535-6108(20)30660-7

Int Immunopharmacol, 2020, 13;84:106583

Catalog No.	Information	Product Use Citations	Product Validations
S7803^New	GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.	Hum Exp Toxicol, 2020, 960327120979028
S8141	Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.	Ecotoxicol Environ Saf, 2021, 211:111900 Cancer Cell, 2020, S1535-6108(20)30660-7 Int Immunopharmacol, 2020, 13;84:106583