Home Proteases -Epigenetics -Metabolism PAD

PAD

Choose Selective PAD Inhibitors
Isoform-selective Inhibitors

PAD Products

  • All (3)
  • PAD Inhibitors (3)
  • New PAD Products
Catalog No. Product Name Information Product Use Citations Product Validations
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Phytomedicine, 2021, 90:153635
Hum Exp Toxicol, 2020, 960327120979028
S8141 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Cell Mol Immunol, 2022, 10.1038/s41423-022-00845-6
Theranostics, 2021, 11(19):9431-9451
Int J Mol Sci, 2021, 22(23)12852
S9644 BMS-P5 BMS-P5, a potent selective pharmacological inhibitor of PAD4, is used to evaluate the effect of PAD4 inhibition on multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation.
S7803 GSK484 HCl GSK484 HCl, a benzoimidazole derivative, is a selective and reversible inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 50 nM in the absence of Calcium.
Phytomedicine, 2021, 90:153635
Hum Exp Toxicol, 2020, 960327120979028
S8141 Cl-amidine Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Cell Mol Immunol, 2022, 10.1038/s41423-022-00845-6
Theranostics, 2021, 11(19):9431-9451
Int J Mol Sci, 2021, 22(23)12852
S9644 BMS-P5 BMS-P5, a potent selective pharmacological inhibitor of PAD4, is used to evaluate the effect of PAD4 inhibition on multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation.
Tags: PAD inhibitor|PAD agonist|PAD activator|PAD inducer|PAD antagonist|PAD signaling pathway|PAD assay kit