MALT1 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8898 MLT-748 MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state. Selective MALT1, IC50: 5 nM
S7429 MI-2 (MALT1 inhibitor) MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM. Selective MALT1, IC50: 5.84 μM
S9896 JNJ-67856633

JNJ-67856633 (JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease.