Home Biosimilar Antibodies Protein Tyrosine Kinase ROR Zilovertamab vedotin
For research use only. Not for use in humans.

Zilovertamab vedotin

Synonyms: VLS-101, MK-2140

Zilovertamab vedotin (VLS-101, MK-2140) is an antibody-drug conjugate (ADC) composed of a humanised monoclonal antibody targeting ROR1 and the anti-mitotic cytotoxic agent monomethyl auristatin E (MMAE). It has potential for the treatment of lymphoid malignancies.

Zilovertamab vedotin

CAS No. 2376463-48-6

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Quality Control

Batch: D401301 Purity: 99% Protein concentration: 5.27mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation RORγ
S18-000003 0
TMP778 0
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Zilovertamab vedotin (VLS-101, MK-2140) is an antibody-drug conjugate (ADC) composed of a humanised monoclonal antibody targeting ROR1 and the anti-mitotic cytotoxic agent monomethyl auristatin E (MMAE). It has potential for the treatment of lymphoid malignancies.
References

Product Details

CAS No. 2376463-48-6
ADC antiody Zilovertamab
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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